Basic Information

Insect: Anopheles arabiensis
Gene Symbol: ZNF219
Assembly: GCA_016920715.1
Location: NC:95491355-95500581[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 3.5e-05 0.0017 18.2 0.6 1 23 128 150 128 150 0.99

2 11 9.5e-05 0.0046 16.8 2.8 1 23 156 179 156 179 0.96

3 11 2.1e-06 0.0001 22.0 0.4 1 23 185 207 185 207 0.99

4 11 6e-06 0.00029 20.6 0.2 1 23 213 235 213 235 0.98

5 11 0.0083 0.4 10.7 3.0 1 23 241 263 241 263 0.98

6 11 9.2e-06 0.00044 20.0 3.1 1 20 269 288 269 292 0.95

7 11 0.04 1.9 8.6 5.4 1 23 298 318 298 318 0.97

8 11 1.1e-05 0.00054 19.7 0.1 3 23 326 346 325 346 0.98

9 11 1.6e-05 0.00075 19.3 1.1 1 23 352 374 352 374 0.99

10 11 1e-05 0.00049 19.9 1.0 1 23 380 403 380 403 0.97

11 11 0.016 0.75 9.9 1.2 1 20 409 428 409 429 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	3.5e-05	0.0017	18.2	0.6	1	23	128	150	128	150	0.99
2	11	9.5e-05	0.0046	16.8	2.8	1	23	156	179	156	179	0.96
3	11	2.1e-06	0.0001	22.0	0.4	1	23	185	207	185	207	0.99
4	11	6e-06	0.00029	20.6	0.2	1	23	213	235	213	235	0.98
5	11	0.0083	0.4	10.7	3.0	1	23	241	263	241	263	0.98
6	11	9.2e-06	0.00044	20.0	3.1	1	20	269	288	269	292	0.95
7	11	0.04	1.9	8.6	5.4	1	23	298	318	298	318	0.97
8	11	1.1e-05	0.00054	19.7	0.1	3	23	326	346	325	346	0.98
9	11	1.6e-05	0.00075	19.3	1.1	1	23	352	374	352	374	0.99
10	11	1e-05	0.00049	19.9	1.0	1	23	380	403	380	403	0.97
11	11	0.016	0.75	9.9	1.2	1	20	409	428	409	429	0.92

Sequence Information

Coding Sequence: ATGAAGAAATCAACGCGACAAACTCGAATGTCCCGATACGTGGGGAAGCATTCGCCCAAAATCGCATCTCCAGAAGAAAGCAACAATaatatcaacaacagcaagaacCCGATCGAAACCGTCCCGAAGGTAATCAGCGGTGATGAAGTGATGAGCGATCTCCCTTCGTACATTGTGGAAAAACCGATTGGATACGACGAATCATCCGCGGATGATGAGGAGGATGACAAGTCGATAGTGAAGAAACTAGTAAATGCGTCTGTTGATGCCGGCGAGGGACGAGACGGCGCAGAGTCCGGTAGTGGCACTGATGCGTCCGCATCATCGACCGGTGGGTCTTCGTCATCGAAACGTGGCCGAAAACGTCGTGAACGGAAGCTGTATCAGTGCGAGGTGTGTCAAAAGGACTTCATGGGCACCAACGATTTGCGCAAACATTTGCGAATACATAACGACGAACGGCCGTACCCGTGTCCACACTGCAAGAACCGCTTCCGGCAGGCGGGATGCCTGAAGAATCACATCGCCTCGCAACACGGCACGGACGAGCAGTATACTTGCGACCTGTGCGGCAAATCATTCCCGATCAAGGAGCGTCTACGGTTGCACATGCGTATCCACACCGGCGAAAAACCATACAGCTGCTCGCTATGCCCAAAAACTTTCGCACGTGGTGGTCAATTGACCCAACATCTTGCTACACACAATGGTGTGAAGAAGCACAAATGTGACCAGTGCACGGCAGCTTTCTCCTGTGCGGCTAATCTGAAGATGCATCTTAAAAGCCACATGGATATTCGTGACTATACGTGCCATATCTGTGGCCGCGGATTCTATAGGCCAGATGCTTTGAAAAAACATCTGCTTTGCTATCATGCCAACCTGAAGGCATTTCACTGCAgcatttgcaataaaatgtttaagGGCCATTTACCACAGCACATGCGAACGCATCTAAAGGTTCGTCCTCACGGTTGTGCTGTATGCGGTTCGGTGTTTTCTCAGCGATCACAGTTGATCGTTCACCAGCGAATTCATAGCGGTGAACGTCCCTATCGTTGCCAGGTTTGCTGGCAGGCGTTTGCACACTCAAGTGTGCTGAAGCTGCACATCCGTAAACACACTGGCGAAAAACCGTTTGAATGTCCGCTTTGTTCATCAAGCTTTTCGCAGCTACCACATTTAAAGAAGCATATGCTGTCTATACATCAGCAGGACAAATCGTACCTATGTCAAAAGTGCAAagaatttttcaaaaccaaGATGGATTACCAATTACACGTTACGGCGTGTTACAAGGATCCGGCAGCTGTGAAGAATCTCGACAATATGATGGACCCAATGTATCGACCGACCGAAAACAATGGCGTTGATCCACCAATGACTATTTCTAGAATGCGTTTTCTAGTGGCCATTTTGCTGAAGAAAATTTCTAATGAGGATCGGCTGAAGGAGCTGGGCTTCGATAAGCGATTGATTGACAATGTTCTAATTGATTCCTTAAAATGTGCTGGCCGAAAGGTTTGCGATGACAAATCGTATGATCCTTTGGAACGATTGAAGCTAAACGTGCAGGAGCTTCTCGAATGGACAGTGCCGCCCAATTACATGGAAGAGTTTCGTGGTGCCAATCGTAGTACGGAGGAGTTGCTTGAGGAACTAACAAACTAA
Protein Sequence: MKKSTRQTRMSRYVGKHSPKIASPEESNNNINNSKNPIETVPKVISGDEVMSDLPSYIVEKPIGYDESSADDEEDDKSIVKKLVNASVDAGEGRDGAESGSGTDASASSTGGSSSSKRGRKRRERKLYQCEVCQKDFMGTNDLRKHLRIHNDERPYPCPHCKNRFRQAGCLKNHIASQHGTDEQYTCDLCGKSFPIKERLRLHMRIHTGEKPYSCSLCPKTFARGGQLTQHLATHNGVKKHKCDQCTAAFSCAANLKMHLKSHMDIRDYTCHICGRGFYRPDALKKHLLCYHANLKAFHCSICNKMFKGHLPQHMRTHLKVRPHGCAVCGSVFSQRSQLIVHQRIHSGERPYRCQVCWQAFAHSSVLKLHIRKHTGEKPFECPLCSSSFSQLPHLKKHMLSIHQQDKSYLCQKCKEFFKTKMDYQLHVTACYKDPAAVKNLDNMMDPMYRPTENNGVDPPMTISRMRFLVAILLKKISNEDRLKELGFDKRLIDNVLIDSLKCAGRKVCDDKSYDPLERLKLNVQELLEWTVPPNYMEEFRGANRSTEELLEELTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100454;
90% Identity: iTF_00105288;
80% Identity: iTF_00095787;