Basic Information

Insect: Anopheles arabiensis
Gene Symbol: -
Assembly: GCA_016920715.1
Location: NC:68631130-68636393[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.29 14 5.9 8.5 1 20 295 314 295 317 0.94

2 16 7.7e-05 0.0037 17.1 2.2 1 23 323 345 323 345 0.97

3 16 2.8e-06 0.00013 21.7 2.6 1 23 351 373 351 373 0.95

4 16 0.00039 0.019 14.9 2.4 2 23 380 401 379 401 0.97

5 16 0.0002 0.0095 15.8 2.4 1 23 407 429 407 429 0.98

6 16 7.6e-05 0.0036 17.1 5.6 1 23 435 457 435 457 0.99

7 16 1.3e-06 6.3e-05 22.7 2.9 1 23 463 485 463 485 0.99

8 16 0.0018 0.084 12.8 1.0 1 23 491 513 491 513 0.98

9 16 0.015 0.73 9.9 3.3 2 20 894 912 893 915 0.94

10 16 3.1e-05 0.0015 18.4 1.0 1 23 921 943 921 943 0.97

11 16 1.7e-06 7.9e-05 22.4 1.3 1 23 949 971 949 971 0.95

12 16 0.00024 0.012 15.5 0.1 3 23 979 999 977 999 0.96

13 16 0.0049 0.24 11.4 2.5 1 23 1005 1027 1005 1027 0.95

14 16 1.6e-05 0.00074 19.3 1.1 1 23 1033 1055 1033 1055 0.98

15 16 0.003 0.15 12.1 5.1 1 23 1061 1083 1061 1083 0.98

16 16 0.073 3.5 7.8 0.1 1 23 1087 1109 1087 1109 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.29	14	5.9	8.5	1	20	295	314	295	317	0.94
2	16	7.7e-05	0.0037	17.1	2.2	1	23	323	345	323	345	0.97
3	16	2.8e-06	0.00013	21.7	2.6	1	23	351	373	351	373	0.95
4	16	0.00039	0.019	14.9	2.4	2	23	380	401	379	401	0.97
5	16	0.0002	0.0095	15.8	2.4	1	23	407	429	407	429	0.98
6	16	7.6e-05	0.0036	17.1	5.6	1	23	435	457	435	457	0.99
7	16	1.3e-06	6.3e-05	22.7	2.9	1	23	463	485	463	485	0.99
8	16	0.0018	0.084	12.8	1.0	1	23	491	513	491	513	0.98
9	16	0.015	0.73	9.9	3.3	2	20	894	912	893	915	0.94
10	16	3.1e-05	0.0015	18.4	1.0	1	23	921	943	921	943	0.97
11	16	1.7e-06	7.9e-05	22.4	1.3	1	23	949	971	949	971	0.95
12	16	0.00024	0.012	15.5	0.1	3	23	979	999	977	999	0.96
13	16	0.0049	0.24	11.4	2.5	1	23	1005	1027	1005	1027	0.95
14	16	1.6e-05	0.00074	19.3	1.1	1	23	1033	1055	1033	1055	0.98
15	16	0.003	0.15	12.1	5.1	1	23	1061	1083	1061	1083	0.98
16	16	0.073	3.5	7.8	0.1	1	23	1087	1109	1087	1109	0.96

Sequence Information

Coding Sequence: ATGGAGGAAgagtttttgattttaaacCTAAAACCGACGACCTGCCGTATCTGTGCGACGGTCAGCGTCGAACAGTACTGCATCTACGAAACGATCTACAAGGACGGTACGCTTAGCATGCACGCGATGATGGAAAAGCTGGTTCCCTCGGTGTTCAACCCGGAGCAGATGAAGGTGGACGAGTACATGTGCTGGCCGCGGAAGGTGTGCGAAGACTGCCGGGCCAAGGTGCTGGAGGCGTACGCACTGTACGAGCAGTGCATGCGGAGTGGCGATCTGCTGCGCGAATGCTTGTCGCGCAAACCGGGTGCGCTGGTCATTGAAAACACGTACGACGATGAGCTGAAGCAGGACTATGCGATCGAAACGACGGTGGAGGAGACAGTGTCGGACTTTGTCGATCACGACGAACCGATCGTGCTGGATCAGAGCACGGAGAGTAGCGTCGGCACTGCCACCGGCCGGCGGGTTAGAAAACAAATCTCGAAAGAGCCAAAATCGGGCAAGAAACAAAAGCCAGATTTGGTGGAACCGCGTACCCCATCGCCGACCGATGACTTTGGCTGTGATTCGGAGGAACAGGACGAAAAACCGCTCAGCAGCTTGGTGGGGAGCGAAAAAGTGGCACGCAAATCGCGATCGGCACGAAACGCAAGCGCTAAGCGCAACAGTTCGGCTACCGGAAAAAGCAACGAGCAACGAACGCGTGGAAAGAAGGGACCTGGCAGGAAGCCAAAGCAACCAAAGGAGGAAAGTGACAACGATACGGAGGAACCGAAAACGAAGGTCGACCTGTACCGCTGTCTGCTGTGCGATGCACCGACCTACACCTCGCCGAAGGAGCACACCGACCATCTGCTGAAGGAACATCCGGACCAGATACATTGCTGCAAGCAGTGCCCGAAGGTGTTCATGACCAAGGCGGCCTTCGAGCATCACCAGTACTGTCACGCGACGGGGCGTTCGTTTTTCTGCATGTTTTGCGACAAAGGCTTTCAGACGGAGCAGCTGCTGAAGAACCACATGCGGACGCATACGCACGGGACCGGGTTCCTGTGCTCGCACTGTGGGCAGGAGTTTAGTAATCGGAGCAATCTACGCCAGCACCTGATACGGCACACGGGTGAGAAGCCGTGGCAATGTAATCTGTGCCCGAGTCGTTTCAGTATGAAGAGTTACCTGGACAGACATATGCACACCCACACGAAAGCCAAGTTTTTCAGCTGCGACACGTGTGGGTCACAATTTAGCCGACACTATTCGCTGGTGAAGCATCAACTAATCCACACAGGAGATCGTCACTTTACCTGTGAGGTTTGCAGTATGCGATTCACCTCGAGCCACCACGTTAAACGGCACATGCTTACACACACCGGCGAGAAACCGTTCAAGTGTACGTACTGTGAGCGCAGCTTCACGCAAAGCAACGACATGGTGAAGCACATGAAAACGCACGTGGGTGAAAATCCGTACCAGTGCGATCGGTGTGAAGCATCGTTCCGGCTGCTCACCGACCTGCGCAACCACTACAAGGACCACTATCTGCCGGGCGGCAAGGATGCACTGTCCGGTGAGGAGGACAAGGGTACGATACGGTTTACCAGCACGAATATACTGAAAATTCGGtacgaaaaggaaagaaacagTGGTCGGCCGGTTAAGCAGGAGGTACGGGCGGCTGGGCACAATCAAACGATGATTCCGGAATGTAAACAACCCACAGCTGTAGCGCAGCTGCTTCGCCTTACCCACCACAGTGTCGCAAAACTTTCTCTGCCGCCGCCTCCAGCTACGATGGAGAAGGAACAGCCCCAAGACCAAACCATGACGATACAGCTAACGTTCTGTCGCATCTGTGCCGTCCTCAGCACGGAGGAGCATTGCATCTACGAAGTGGCGTACAGTGCCGGCACACTCAGCATGCACGCGATGATGGAAAAGCTAGTTCCCTCGGTGTTCAACGCGGAGCAGGTAAAGGTGGACGAGTTTATGTCCTTTCCCACGAAAGTGTGCGGCAGTTGCAAAGCCAAAGTGCTCGAGGCGTACGGGCTGTACGAGCAGTGCGTGAGGAGTGGCGATCTGCTGCGCGACTGTTTAGCGCGTAAGAAAAACGCAACGTTCATCGTGAACATTaccggtgctggtggtggtggtggtagtggcggGGCGGATAGTTCCGAGGGCAAACTGATTGTCCCGCTGGCGTACGAAACGGAGGAAGTGTCGGTAGGTGGCAAACCTCACACTACAACGGTGGTTGAGATAACGACGGAAGAAATCGGCCCACACCGTAAGGTGGAAAGTGAAGGCGAAAGTGAGATAGTGGAGTTGGTTCCTAGCCTTATTGATGAAGATGCCGCTGAACATGTTGCCTCGGAACAGGGAGATCATCCGACGTGTTCCGAGGGGGAAACTGTAACGATACCTGCTGCCAAGGTAAAGCACGAAACGAGTAGAGCAAAACATGCACGAACACGTGCGACAACGAAAAGAAACgtaaagcaagcaaaaacgaCGAAAAGAAAGCAGGACGACACTGCCGACGTGCTGTTGGAAACAACGGAACAACCAAAACTGAATCCCGTTCAATTGCGCTGCCTACTGTGCAATCGACCAGCGTTTGCCGCACCGGCGGAACTTACGCAGCACCTGCACAGCGAGCATGCGGATCAAATTTTGCGCTGCAACCTCTGCCCGAAAGTGTTCATGACCAAGGTGGCCTTCGAGCATCACCAGTACTGTCACGCGACGGGGCGATCGTTCTTTTGCGCGCTGTGTGATAAAGGCTTTCAGTCGGAGCAGCTGCTGAAGAACCACATGCGGACGCACACGCACGGGACCGGGTTCCTGTGCTCGCAGTGTGGCAAAGAGTTTAGCGATCGAAGCAACCTGCGCCAGCACGAGCAGCGCCACACCGGCGAGAAACCCTGGGCATGCAGCATGTGTCCAAGCCGGTTTAGCACGAAGGGCTATCTGACGGTACATTTGGCCACCCATACAAAAACGAAAGCATTCAGCTGCGACACGTGCGGATCACAGTTTAACCGGCACTACTCACTGGTGAAGCATAAGGTCATCCACACAGGAGAGCGTCACTATGCCTGCGAAGTTTGCAAGATGAGGTTCGCGTCGGCGTACCATGTGAAAATACACATGCGAACGCACACCGGTGAAAAGCCGCACAAATGTGGCTACTGTGCCCGTGGCTTTGCGCAGAAGAACTGCATGCTGAAGCATATGAAAACGCACGGCAAACCGTACCCGTGCGACCGGTGCGATGCATCGTTTCATGCGATAGCGGATTTGCGGGTACACGCGAAGGAGCACGATCGGGTACGGAAGCAGGAAGAGGTTGATGCCCCTGCGGAACAATAA
Protein Sequence: MEEEFLILNLKPTTCRICATVSVEQYCIYETIYKDGTLSMHAMMEKLVPSVFNPEQMKVDEYMCWPRKVCEDCRAKVLEAYALYEQCMRSGDLLRECLSRKPGALVIENTYDDELKQDYAIETTVEETVSDFVDHDEPIVLDQSTESSVGTATGRRVRKQISKEPKSGKKQKPDLVEPRTPSPTDDFGCDSEEQDEKPLSSLVGSEKVARKSRSARNASAKRNSSATGKSNEQRTRGKKGPGRKPKQPKEESDNDTEEPKTKVDLYRCLLCDAPTYTSPKEHTDHLLKEHPDQIHCCKQCPKVFMTKAAFEHHQYCHATGRSFFCMFCDKGFQTEQLLKNHMRTHTHGTGFLCSHCGQEFSNRSNLRQHLIRHTGEKPWQCNLCPSRFSMKSYLDRHMHTHTKAKFFSCDTCGSQFSRHYSLVKHQLIHTGDRHFTCEVCSMRFTSSHHVKRHMLTHTGEKPFKCTYCERSFTQSNDMVKHMKTHVGENPYQCDRCEASFRLLTDLRNHYKDHYLPGGKDALSGEEDKGTIRFTSTNILKIRYEKERNSGRPVKQEVRAAGHNQTMIPECKQPTAVAQLLRLTHHSVAKLSLPPPPATMEKEQPQDQTMTIQLTFCRICAVLSTEEHCIYEVAYSAGTLSMHAMMEKLVPSVFNAEQVKVDEFMSFPTKVCGSCKAKVLEAYGLYEQCVRSGDLLRDCLARKKNATFIVNITGAGGGGGSGGADSSEGKLIVPLAYETEEVSVGGKPHTTTVVEITTEEIGPHRKVESEGESEIVELVPSLIDEDAAEHVASEQGDHPTCSEGETVTIPAAKVKHETSRAKHARTRATTKRNVKQAKTTKRKQDDTADVLLETTEQPKLNPVQLRCLLCNRPAFAAPAELTQHLHSEHADQILRCNLCPKVFMTKVAFEHHQYCHATGRSFFCALCDKGFQSEQLLKNHMRTHTHGTGFLCSQCGKEFSDRSNLRQHEQRHTGEKPWACSMCPSRFSTKGYLTVHLATHTKTKAFSCDTCGSQFNRHYSLVKHKVIHTGERHYACEVCKMRFASAYHVKIHMRTHTGEKPHKCGYCARGFAQKNCMLKHMKTHGKPYPCDRCDASFHAIADLRVHAKEHDRVRKQEEVDAPAEQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -