Basic Information

Insect: Anopheles arabiensis
Gene Symbol: -
Assembly: GCA_016920715.1
Location: NC:68644910-68650171[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.2 57 3.9 0.3 1 23 345 369 345 369 0.91

2 18 0.035 1.7 8.8 2.8 2 20 375 393 375 396 0.94

3 18 0.0035 0.17 11.9 2.3 1 23 402 424 402 424 0.97

4 18 2.4e-06 0.00012 21.9 1.9 1 23 430 452 430 452 0.94

5 18 0.00019 0.0092 15.9 1.5 3 23 460 480 458 480 0.97

6 18 0.00019 0.0093 15.9 1.9 1 23 486 508 486 508 0.98

7 18 7.5e-05 0.0036 17.2 2.2 1 23 514 536 514 536 0.98

8 18 2e-06 9.7e-05 22.1 2.0 1 23 542 564 542 564 0.99

9 18 0.0075 0.36 10.9 0.4 1 21 570 590 570 591 0.96

10 18 0.74 35 4.6 0.0 1 23 929 953 929 953 0.92

11 18 0.026 1.2 9.2 3.5 3 20 960 977 959 980 0.94

12 18 0.00053 0.025 14.5 1.2 1 23 986 1008 986 1008 0.97

13 18 6e-07 2.9e-05 23.8 2.3 1 23 1014 1036 1014 1036 0.93

14 18 0.003 0.15 12.1 5.8 2 23 1043 1064 1042 1064 0.96

15 18 0.00056 0.027 14.4 1.3 1 23 1070 1092 1070 1092 0.98

16 18 8.5e-06 0.00041 20.1 0.9 1 23 1098 1120 1098 1120 0.98

17 18 2.4e-06 0.00011 21.9 1.5 1 23 1126 1148 1126 1148 0.99

18 18 0.00044 0.021 14.7 0.9 1 23 1154 1176 1154 1176 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.2	57	3.9	0.3	1	23	345	369	345	369	0.91
2	18	0.035	1.7	8.8	2.8	2	20	375	393	375	396	0.94
3	18	0.0035	0.17	11.9	2.3	1	23	402	424	402	424	0.97
4	18	2.4e-06	0.00012	21.9	1.9	1	23	430	452	430	452	0.94
5	18	0.00019	0.0092	15.9	1.5	3	23	460	480	458	480	0.97
6	18	0.00019	0.0093	15.9	1.9	1	23	486	508	486	508	0.98
7	18	7.5e-05	0.0036	17.2	2.2	1	23	514	536	514	536	0.98
8	18	2e-06	9.7e-05	22.1	2.0	1	23	542	564	542	564	0.99
9	18	0.0075	0.36	10.9	0.4	1	21	570	590	570	591	0.96
10	18	0.74	35	4.6	0.0	1	23	929	953	929	953	0.92
11	18	0.026	1.2	9.2	3.5	3	20	960	977	959	980	0.94
12	18	0.00053	0.025	14.5	1.2	1	23	986	1008	986	1008	0.97
13	18	6e-07	2.9e-05	23.8	2.3	1	23	1014	1036	1014	1036	0.93
14	18	0.003	0.15	12.1	5.8	2	23	1043	1064	1042	1064	0.96
15	18	0.00056	0.027	14.4	1.3	1	23	1070	1092	1070	1092	0.98
16	18	8.5e-06	0.00041	20.1	0.9	1	23	1098	1120	1098	1120	0.98
17	18	2.4e-06	0.00011	21.9	1.5	1	23	1126	1148	1126	1148	0.99
18	18	0.00044	0.021	14.7	0.9	1	23	1154	1176	1154	1176	0.98

Sequence Information

Coding Sequence: ATGGACATGAAGGATGAGGAATATCCTTCCACAGCGGCGCTCGAGCCGGAGTGGTGCCGGGTCTGCGTGTCCGAGCCGGAGGCGATACACGGCATGGACGAGATGATAGACGCCGACCATTCGGTAAGCCTTAACATGATGCTGGAGGCAATGTTTCCCATGTTTGCCAGTCCGGAAGGGAAAGATTCACAAACCACCCAGCAACACTTGCCAACGAAAGCGTGCGATAGCTGCAAGCACAAGATCATGATCGCGTACGGGCTGTACCTGCTGCTGATAGAGAGCGAAGAGCGGCTGCAGCGCTATCTAGGGGAAGCTCCACGGTCCTGCACGGACGATGAGAAGGCGGAACAATCCTGTGCACCGTACGAGGTGCTGATCGAGTGTAGCTTTGACGATGGCGAGACAGCACTGTCGAGGGAGGAGGAACCACCCGCCTTGCGGCCGTTGGAAGCGTTGGACGAGGAAAGTGTACCGCGGAAAAGAGGCAGACCACGAACCCGGCCACTACCACAGACCACCACCGTGCTCTTGGAGGAGGACAAGCGACCGAAGCGAATGAGTAAACAGGACCGGACCAACGAGAGCGTCACGGAAGAGGAGCAAATGGTGCTGGAAGAAGATATCGTTCTGCTGGATGAATTCACGGGAGAACAAACCTCCCAACCAGTGGCAAAGAAACGGGGTCGAAAGCCCAAAGTTCGGGCAGATAGTACCGATCAGCTGCATGAATCCACCACGGAACAAGCAATCGAACCACCGGTGGCAAAGAAACGGGGTCGAAAGCCCAAAATTCGGGCAGAAAGTACCGATCAGCTGGATGACTCCACGGCAGAACAAACCGTCGAACCACCGGTGGCAAAGAAACGGGGTCGGAAGCCCAAAATTAAATCCGAACCAGCTGAAGGCGATGAAAGCAGCACGGAAGGCAGGAAGGAACGGAAGCAAAGCGCAACGATCAAGGTGGAAGCGGCCGAATATTTGTCGGATCAGGGTGGCAGTGGCGTTGAGCTAGAGTCTAAGGTGGACGTGTACAACTGTCAGCTGTGCGAGGGGCACACGTATGGGTCGCCCACCGAGCTGACGGAGCATCTGAAGGCGGAACATCCGGACCTGATACGCACGTGCGACAAGTGTCcgaaggtgttcatgacggAGGCAGCGTACCAGCATCACCAGTACTGCCATGCGACGCTGCGCTCCTACTTCTGCATGTTCTGCGACAAGGGTTTCCAGACGGAGAATCTGCTGAAAAGCCATACCAAGTCGCACACGGAGATGGCCGAGTTTTTGTGCTCGCTGTGTGGGAAGAAGTTCAACAACAAGAGCAACCTGCGGCAGCATCTGGTGCGCCACACGGGCGTGAAACCGTGGGCCTGTACGCAGTGCCCGAGCCGGTTCTGTACGAAGGGTGCATTAAACTTACACCAGAGAACACACTCGAAGCTAAGACCGTTCAGTTGCGATATTTGTGGCTCACAGTTCCACACACGATACTCCCTGATCAAGCACCAGCTAATCCATACAGGTGAACGTCCGTACAGTTGCGATCTCTGCCCGATGAGATTCGTCTCGACCTACCACGTGAAGCGGCACATGCTTACGCACACCGGTGAAAAGCCGTTCAAATGCACGTACTGTGAGCGCAGCTTCGCGCAAAGCAACGACATGGTGAAGCACATGAAAACGCACGTGGGCGAAAACCCGTACCAGTGCGATCGGTGTGAAGCATCGTTCCGGCTGCTCACCGATCTGCGCAACCACTACAAGGAGACGTGCACGCCGGTCGATAAAGGGGCCGGTTCGTCCGCGGACGAGGGGAAAGCGATACGGTTCACAAGCACAAGCATTTTGAAGATGCGATACGAGAAAGAGATGGGCCAGTACAGCGAGCAGCGGTACGAGGAAAGCGCTGGCCAGCGGAAAGTTATGGCAGAGGCGACCGAGTTTCCTGCAATGGAATCCGCGATGGACGTGGACGTGGTATGGCCATCGACCGACGCAACGGCGTGCTGCCGCATCTGCGTGCTAGAGACGGAGGCGGCGGACGCGTGCCGCATGCACGAACCGCTGGAGGAAAATGGGTCCCAGAGCCTGCAGATCGTGCTGGAGAAGCTGTTCCCGGGCGTGTTCAACGAGGAGCAGGTGCAGCACGACTACACCATGAACTGGCCGATGGTGGTGTGCCGGGAGTGCAAGCGCAAGGTGCAGGAAGCGCACGAGCTGTACGAGACCTGTCTCGATAGCCGCGGCCGGCTGCAGAAACGTTCCGCCAAGGAGGAAATGCACGCAGACGAAGAGATCGTGCCGGTGGACTGTGTGGTGGACGAGCAGGCGCAAGAGTTCCTGGAGTGCGATCTCATCCCGGAAACGGAGCTCGAGCCGGAGCTCGAACCACTGCCCGCCTCATCGCGCCGACGTACGGCGAAGGCGCGTAAAAGCGAACCCGCACCGAAGGGCTCGAGGACGAAGAAAGCGCACACCGCACCTGCGGAGGTGATGGAAATCAAGAAGGAGCTGGAGGACCCACAGGAGCAACTGCAGGAGGAGCAGCAACCGGAGGTGGAAATGCTCGAAGAGGAGGAGTTAGAGTTTGCCGAGGAAAGCAACAGCGCAGAGCCGGAATGGACACCACCGTCGTCCGCCGGCAGGGCCAAGAAAGCGAGAGGCGCACCGAAAGCGAAGCCGACCGACGAGAAGGTGCCGAAGGAAAGGAAGAAGCGCGAGCGTAAGCCAAAGGTCGAGCCGGGCGCGGAGGGAAAGCTCGAATCCAAGACGGAGCTGTACCGGTGCCAGCTGTGCTCGGGGCCAACCTACGAGACGCCCGGCGAGCTGACGGAGCATCTGAAGGCGGAACATCCGGCCCAGATACGGCCGTGCGACAAGTGCCCGAAGGTGTTCGTCAGCGAGCAAACGTTCCAGCACCACCAGTACTGTCACGCGACCGGTCGGTCGTTCTTCTGCGACTTCTGCGACAAGGGCTTCCAGACGGAGGGGCTGCTGACGAGCCACACCAAGTCGCACACGCGCGGTCCCAAGTTCCTGTGCTCGTACTGCGGCAAGGGGTTCACCACCAAGAGCAGCCTGCAGAAGCATATGACATTCCATACGGACAGCAAATCGTGGCCGTGCCGTCTGTGCCCCTGTCGGTTCAATACGAAAGCCTGCCTGCACGTGCATATGCGtacgcacacaaaaacgaaGATCTATACCTGCCCAATCTGTGGCTCGCAGTTTAACAAACACTACTCGATGGTGAAGCATCAGATCATTCACACAGGAGAACGCCCATTTGTCTGTGAGCTTTGTCCCATGAGGTTTGTCTCGCCGTACCACGTGAAACGGCACATGCTAACGCACACCGGGGAAAAGCCCTACAAATGTACGTACTGTGAGCGCAGCTTCGCGCAAAGCAACGTGCTGGTGAAGCACATGAAAACGCACGTCGGCGACCATCCGTACCAGTGCGATCGGTGTGACGCGTCCTTCCGGCTGCTGAAGGACCTGCGCAACCACTACCAGGAGCACTACGTGGAGAGCGAGAACGGTATCGGGCCGTCGCCGGTCGTGGACGATAAGGATATACGCTTTACCAGCACGGAAATCTTGAAGCTGCGATACCAAAAAGAGATGGGCCAGTACAGCCAAAAGTATGAGGGCAGCGGTGGTGACGATTGA
Protein Sequence: MDMKDEEYPSTAALEPEWCRVCVSEPEAIHGMDEMIDADHSVSLNMMLEAMFPMFASPEGKDSQTTQQHLPTKACDSCKHKIMIAYGLYLLLIESEERLQRYLGEAPRSCTDDEKAEQSCAPYEVLIECSFDDGETALSREEEPPALRPLEALDEESVPRKRGRPRTRPLPQTTTVLLEEDKRPKRMSKQDRTNESVTEEEQMVLEEDIVLLDEFTGEQTSQPVAKKRGRKPKVRADSTDQLHESTTEQAIEPPVAKKRGRKPKIRAESTDQLDDSTAEQTVEPPVAKKRGRKPKIKSEPAEGDESSTEGRKERKQSATIKVEAAEYLSDQGGSGVELESKVDVYNCQLCEGHTYGSPTELTEHLKAEHPDLIRTCDKCPKVFMTEAAYQHHQYCHATLRSYFCMFCDKGFQTENLLKSHTKSHTEMAEFLCSLCGKKFNNKSNLRQHLVRHTGVKPWACTQCPSRFCTKGALNLHQRTHSKLRPFSCDICGSQFHTRYSLIKHQLIHTGERPYSCDLCPMRFVSTYHVKRHMLTHTGEKPFKCTYCERSFAQSNDMVKHMKTHVGENPYQCDRCEASFRLLTDLRNHYKETCTPVDKGAGSSADEGKAIRFTSTSILKMRYEKEMGQYSEQRYEESAGQRKVMAEATEFPAMESAMDVDVVWPSTDATACCRICVLETEAADACRMHEPLEENGSQSLQIVLEKLFPGVFNEEQVQHDYTMNWPMVVCRECKRKVQEAHELYETCLDSRGRLQKRSAKEEMHADEEIVPVDCVVDEQAQEFLECDLIPETELEPELEPLPASSRRRTAKARKSEPAPKGSRTKKAHTAPAEVMEIKKELEDPQEQLQEEQQPEVEMLEEEELEFAEESNSAEPEWTPPSSAGRAKKARGAPKAKPTDEKVPKERKKRERKPKVEPGAEGKLESKTELYRCQLCSGPTYETPGELTEHLKAEHPAQIRPCDKCPKVFVSEQTFQHHQYCHATGRSFFCDFCDKGFQTEGLLTSHTKSHTRGPKFLCSYCGKGFTTKSSLQKHMTFHTDSKSWPCRLCPCRFNTKACLHVHMRTHTKTKIYTCPICGSQFNKHYSMVKHQIIHTGERPFVCELCPMRFVSPYHVKRHMLTHTGEKPYKCTYCERSFAQSNVLVKHMKTHVGDHPYQCDRCDASFRLLKDLRNHYQEHYVESENGIGPSPVVDDKDIRFTSTEILKLRYQKEMGQYSQKYEGSGGDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -