Basic Information

Insect: Anopheles arabiensis
Gene Symbol: -
Assembly: GCA_016920715.1
Location: NC:2493246-2495502[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 2.4e-05 0.0012 18.7 0.7 3 23 30 50 28 50 0.96

2 17 0.63 30 4.8 9.9 1 23 56 78 56 78 0.97

3 17 0.0013 0.064 13.2 4.5 1 23 84 106 84 106 0.94

4 17 0.0027 0.13 12.2 0.2 2 23 112 134 112 134 0.95

5 17 0.00022 0.011 15.7 1.9 2 23 141 162 141 162 0.97

6 17 0.0098 0.47 10.5 1.3 3 23 167 188 166 188 0.95

7 17 0.0002 0.0095 15.8 0.4 1 21 195 215 195 216 0.94

8 17 0.048 2.3 8.3 8.9 1 23 221 244 221 244 0.98

9 17 0.22 10 6.3 0.1 2 23 380 401 379 402 0.93

10 17 4e-05 0.0019 18.0 3.6 1 23 407 430 407 430 0.98

11 17 5.1e-05 0.0024 17.7 0.1 2 23 436 457 435 457 0.96

12 17 0.0025 0.12 12.4 1.1 1 23 463 485 463 485 0.97

13 17 0.00025 0.012 15.5 1.4 1 23 491 513 491 513 0.98

14 17 3.9e-06 0.00019 21.2 0.1 1 23 519 541 519 541 0.98

15 17 0.00043 0.021 14.8 0.0 3 23 549 570 547 570 0.95

16 17 4.6e-07 2.2e-05 24.1 1.2 1 23 583 605 583 605 0.96

17 17 2.8e-06 0.00013 21.7 0.8 1 23 611 634 611 634 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	2.4e-05	0.0012	18.7	0.7	3	23	30	50	28	50	0.96
2	17	0.63	30	4.8	9.9	1	23	56	78	56	78	0.97
3	17	0.0013	0.064	13.2	4.5	1	23	84	106	84	106	0.94
4	17	0.0027	0.13	12.2	0.2	2	23	112	134	112	134	0.95
5	17	0.00022	0.011	15.7	1.9	2	23	141	162	141	162	0.97
6	17	0.0098	0.47	10.5	1.3	3	23	167	188	166	188	0.95
7	17	0.0002	0.0095	15.8	0.4	1	21	195	215	195	216	0.94
8	17	0.048	2.3	8.3	8.9	1	23	221	244	221	244	0.98
9	17	0.22	10	6.3	0.1	2	23	380	401	379	402	0.93
10	17	4e-05	0.0019	18.0	3.6	1	23	407	430	407	430	0.98
11	17	5.1e-05	0.0024	17.7	0.1	2	23	436	457	435	457	0.96
12	17	0.0025	0.12	12.4	1.1	1	23	463	485	463	485	0.97
13	17	0.00025	0.012	15.5	1.4	1	23	491	513	491	513	0.98
14	17	3.9e-06	0.00019	21.2	0.1	1	23	519	541	519	541	0.98
15	17	0.00043	0.021	14.8	0.0	3	23	549	570	547	570	0.95
16	17	4.6e-07	2.2e-05	24.1	1.2	1	23	583	605	583	605	0.96
17	17	2.8e-06	0.00013	21.7	0.8	1	23	611	634	611	634	0.95

Sequence Information

Coding Sequence: atgCAACCCACCGAAGAAAATGGGGAAGGAATTGAACCAACACCGACAGAACACCCAGCCGAGAGCGAAAGCAAAGCTCCCATTATCTGCAGTTTTTGCGATAAGACGTTCAAATACCCCACGATGTTGCGACAGCACGAAAAGATTCACTACGGCATCAAGCAGCACGAATGCGAGGTGTGCCATCGCCGTTTTCTGCACAAAAGCACCCTAACGTGCCACATGCGGCTGCACACGGGCGAAAAGCCGTACAAGTGTCCGCACTGTCCGAAAACATTCCGTGGCCAAACGGCACTCAACTGTCACGTCTTCCGGCACACGAACGAGGGTGCCAAATGTCCCGTATGCTCCAAAGTCTTTGCCACCGGTTCGGTTGTGAAACAGCATCTGAAGCAGGTGCACACCGACGAGCGGCAAAATGTGTGCAATCTTTGCGGTGTGACTTACAAGCATCTGAAGAGCTTGAGGCTGCATCTACGCAACCACCAGAAGCGGATGTGCCCGGAGTGTGGCGTGGGATTTGACAATGTGCATTCCATGCTGAAGCACCGCAAGCACGCGCATGTCAAAGAGAACCTTCCATTCAGATGCGATCACTGCGATCGAGCGTTTGAGCAACGTGCCAAACTCGCTTCCCACGAAAAGCTGCGAGGCCGACCGTTCCAGTGTGAGCTATGTTGCCATAGCTTTAACAAGCAACACTACCTAACGAACCACCAGCGGCGTGCTCACTGGCAGGAGATGGGACTGGAGCGGTTGAAAGTGGCCGAACCACAGAATGGGTGGAATCGGAAGGGAATTCCAAAGCCAAAGCGTAGGAAGAAACTTGCGGAATCGCATGAACCGGAATGTCTTCCGAACGAGAATAATGGAACGCAATCTACAGTGATCGATCAACTTCCAAACAAGCCGGAAACCGGCACACATGAGACTGTGAATAAGAGCATACAATGCGAGGATGGATCTTTTGATCCCCAGATACAACCATCGGAAAATAGAACCGATGAAATGACGATACACGAAGAAGAGATGCTACTCATGaaCTCTTCTAATAACCATACCGAACCGTTggaaattttaaacaatagtCATCATACGACTTCTTCTGGAGAGGAAAACAAAGGCTCAAAGGCGTTAATCTGCGAACTCTGCGGAAACTGGTACGCATCCGCATCAACCCTTGCCATACATCGTGCCAAACACCATCGAGCTGCTCGCTTCCAGTGCGACCAGTGTCCCAAAACGTTCGTTTTTCGGTGCTTCCTTGAGAAGCACATCAAAACCGATCATCAACACGAGCGCGTTTCGTGTGAGCTTTGCGGGAAAGCGTTCAAATACGGACAAGATTTGAAGGTGCACATGCTGCAACACGAGGATCCCAAACCGTACAAATGCGACCAGTGCTCTTCCGCCTTTCGGTTTCGCGGGGCATTGAGATCGCACAAACTGCTGCACCAGAAAGACCTGCCGTTCCGATGTGATATTTGTGCGAAATATTTTCGCTTCGCCAACAGTCTGCGGGTGCACAAACGGCTGCACAGTGGTGTTAAACAATTCATGTGTGAGGTTTGTGATCGAGAGTTTGCCACAAAAGCGCCACTGTTACGACACATGAAGGTTCACGATGCTGGCAGGGAGTTGGCTTGCGGAGTTTGCGGGGCAGtgttttacaaaaaggttGATCTCCAGATACACCAAAGCAAGGAACATTCCGCCCACCAGGCGTTGGGGAAGGTGAAACCCATCTACAGCTGTGACCACTGCGGGAGAGAATTTATCCGGAAAAGTAACCTGAAAGCGCATGCGTACATTCACGAGGAAGTGTACCGGTTTGCATGTGATCTGTGTGGTCAATCGTTCAAGCAACATTCCGGTCTACGAAATCACATGATCAACATTCACAAGCAAGTGCCTGGGTCGTTGGAAACTCCGAACGAACCGTACGAAGATGTGCACCAAGGTgcataa
Protein Sequence: MQPTEENGEGIEPTPTEHPAESESKAPIICSFCDKTFKYPTMLRQHEKIHYGIKQHECEVCHRRFLHKSTLTCHMRLHTGEKPYKCPHCPKTFRGQTALNCHVFRHTNEGAKCPVCSKVFATGSVVKQHLKQVHTDERQNVCNLCGVTYKHLKSLRLHLRNHQKRMCPECGVGFDNVHSMLKHRKHAHVKENLPFRCDHCDRAFEQRAKLASHEKLRGRPFQCELCCHSFNKQHYLTNHQRRAHWQEMGLERLKVAEPQNGWNRKGIPKPKRRKKLAESHEPECLPNENNGTQSTVIDQLPNKPETGTHETVNKSIQCEDGSFDPQIQPSENRTDEMTIHEEEMLLMNSSNNHTEPLEILNNSHHTTSSGEENKGSKALICELCGNWYASASTLAIHRAKHHRAARFQCDQCPKTFVFRCFLEKHIKTDHQHERVSCELCGKAFKYGQDLKVHMLQHEDPKPYKCDQCSSAFRFRGALRSHKLLHQKDLPFRCDICAKYFRFANSLRVHKRLHSGVKQFMCEVCDREFATKAPLLRHMKVHDAGRELACGVCGAVFYKKVDLQIHQSKEHSAHQALGKVKPIYSCDHCGREFIRKSNLKAHAYIHEEVYRFACDLCGQSFKQHSGLRNHMINIHKQVPGSLETPNEPYEDVHQGA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104552;
90% Identity: iTF_00095778;
80% Identity: -