Aara009623.1
Basic Information
- Insect
- Anopheles arabiensis
- Gene Symbol
- -
- Assembly
- GCA_016920715.1
- Location
- NC:78292478-78304360[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 26 0.029 1.4 9.0 0.5 2 23 299 321 298 321 0.95 2 26 0.031 1.5 8.9 1.6 1 23 361 384 361 384 0.93 3 26 0.0014 0.069 13.1 1.2 2 23 391 413 390 413 0.96 4 26 0.0013 0.062 13.3 0.5 1 23 419 442 419 442 0.98 5 26 7.8e-06 0.00037 20.2 3.3 1 23 448 471 448 471 0.96 6 26 1.3 60 3.9 0.2 1 23 477 499 477 499 0.84 7 26 0.0022 0.1 12.6 1.7 1 23 504 527 504 527 0.92 8 26 2.7e-05 0.0013 18.6 2.0 1 23 835 858 835 858 0.96 9 26 0.01 0.49 10.4 0.6 2 23 865 887 864 887 0.94 10 26 0.0021 0.099 12.6 2.3 1 23 893 916 893 916 0.95 11 26 0.023 1.1 9.4 0.6 2 23 923 944 922 944 0.94 12 26 0.00027 0.013 15.4 1.2 3 23 952 972 950 972 0.96 13 26 3.3e-05 0.0016 18.3 6.4 1 23 977 1000 977 1000 0.97 14 26 0.0014 0.068 13.1 3.2 1 23 1248 1271 1248 1271 0.90 15 26 0.00016 0.0076 16.1 0.4 2 23 1278 1300 1277 1300 0.96 16 26 0.0021 0.099 12.6 2.3 1 23 1306 1329 1306 1329 0.95 17 26 0.00033 0.016 15.1 0.9 2 23 1336 1357 1335 1357 0.96 18 26 0.11 5.1 7.2 1.6 1 23 1363 1385 1363 1385 0.91 19 26 9.8e-05 0.0047 16.8 3.8 1 23 1390 1413 1390 1413 0.97 20 26 3.1 1.5e+02 2.6 0.5 3 23 1701 1718 1699 1718 0.77 21 26 0.0016 0.075 13.0 0.3 1 23 1724 1747 1724 1747 0.95 22 26 0.00027 0.013 15.4 0.4 2 23 1754 1776 1754 1776 0.96 23 26 0.00018 0.0086 16.0 2.9 1 23 1782 1805 1782 1805 0.97 24 26 0.0079 0.38 10.8 2.8 2 23 1812 1833 1811 1833 0.96 25 26 0.0069 0.33 11.0 2.0 1 23 1839 1861 1839 1861 0.96 26 26 0.00022 0.011 15.7 2.3 1 23 1866 1888 1866 1888 0.98
Sequence Information
- Coding Sequence
- ATGGAGGCCATCGTACCAAATCTAAACGAAATTTGTCGGCTATGCCTGTGCGAGGACATAAGGTTTCTCATTCCCGCCTCGAAATTGCTCGATGATTCACTTTCCCTGCagcacattgaacggttcaccGGTATTCGGATTCCTCCGAACGACTGTGAATTGTATGCGCTCTGCATGGAATGTGGCAACAAGCTGACCACCAGTGTGGCGTTTCTTGTCTGCTGCAAAAACAACGATACCGTGTTTAGGAATCTGTTCGATCTGCCTGCTCTGGACGCCGCGGGGGAGGATCGAATATTGGTCGATTTTTCGACCGAAGTCAAACAGTCTCCGGAGATCGAAGTATTAGAGGAAGCATGCACAGAGCCAGAGGCGCAAGAGACCCAGGAGGTCCAAGAACTCCCTCataatacaacaacaacggtaTGTACAAAGCCACCGGATGCGACGGAGGACGATCGAGTATCTTCCAATTTTTCATCTCAGCTCAAAAAGTCTCCGGAGATCGAAGTATTACAGGAGCCATGCACTGAGTTAGAGGCGAAAGAGACCCGCGCGGTGCAAAGCCTCTCTCATAATACAACATCAACATGTACAGAGCCACCATCAGCAGCGGGCGAATTTACCATCGATCCGAACGATTTCATAATCGAATCGCTAGACAGCATGATAGACGACGTAATTGTTCACCACGATGGAGGAGCGGAGAGTTTGGACGGCATTGAGCACGCGGTGGCGGAAGACGAACCTCCTGACGATGCGGGAGTGTATTGCTACAATACTTCATCTTCCGACCAGCGCGATGAACGATCGGCGAAACAGGAACTATCTGCAAGCGTCTCTAGCGCATCTCAAATCGAACGGAAACCACCGCTCCACATCCCCACCGACTTGGAATGTTCGGCTTGTGAGATTAAGTTCGTCGACGAAATTACCTTCAAGCGGCATTACCGGCGGTACCACGTGAGCGAGTTGCAGAAAAGTCGCGAGCACCGCAAGAAACGGCAGCTGTGCGTCGAATGCGGCAAGATGGTGCTGCAGCTCTCCGCCCACCGGTTAACCCACACGCAGGAGAAACAGTTTTCCTGTCCCCACTGTCCGATGAAGATGAAAAGCAAGGGCAACATATGCCGGCACATCGAGGCGGTGCACTTGAAGAAGCCGGCGAAAACGTGCGAAACGTGTGGGAGGGAGTTTGTGCACGCCAACATGTACAAGTACCATATGCTTTCCGTTCACGGCATTGGCAAGGCGTACGAGTGTgctatttgtttgaaaaagttCAATGCACTTTCGTCGCTcaaatcacacaaacaaacagcgcaCGAGAAAAGGTCGGCTTTTGAATGCGAAACGTGTGGAAAGAAGTTTAAACGCAGACATACCCTTCAAATGCACATTAAACAAGGACATTCTAACGACAAGCTGTACAGTTGTAGCCTGTGCCCGAAACGGCTCAAAACGCTGCTTGGTAAGCAAGCGCACGAGCTGGCACACAGTGGAGCTGTGTTTGCCTGCACGCTGTGCGACAAAGTGTTCCGGTACAAATGTTTACTGCAAGGGCACGTCAGTCAGGATCACGTAAAAGCGGAAGGCAGGGAAAAGCTTCAAAAAGAGCTTATCATTcaatgtttacaaacaaacacatcagCTTCGCGGTGCGCGATGGCGGCAATTCCACGCGAAATAAATGAAGTCTGTCGGCTTTGCCTGTGCCGGGATGAGAATATTCTCTTTCCTGCGACCAAATTCATCGACTCCCAGCTGACCCTGGACGATGTGGAACGAGTAGCCGGTGTACGGATCGTGGAACAGGAAAGCATGCGCTGCGTGTTGTGTGTCGATTGTAACAACAAACTACGGCACATCAAAGCCTTTAAGGCCTCCTGCATCAGCAATGATGAGACGTTTAGAAAGTGGTTTACAGTGGCCGATAAAGATTGTTCGCGAGACGACACTCATCCACTGAAATTGAATGCTGCAGCGCAAGCATTGAACGGTGCGGCGCGCGAAACTGACCAGTGTAACGATTCGGCGAATGAGTTCGATGAGGCAACATTTTTCGACAACAACATTGAAGTCATCAAGGAAGAAGAAATTGACGACCTGGCGGTCAAATACATCGTTCAAGAAATGTATGAAGACATGGAAGTACTCACGGAAGATGTTGTTGACttcgatgttgatgatgatgatgaagatgctGAAGAATTTGCCGAGGACATGAAAACAGAAGGGAGCCAAACATCGATAGATGATTTCGTTACCAGCGATGATCCGGGCGAGGCGTCCGTACCGTACGAACCGTACGAACGGCAGCCAACAACGCCAAACGAAACTTTCGCACCAGCGATACCAGCGGACCATCAAACAGTAACTGCCGCCGCCAGTGAGGAAAcgggcaagaagaagaatccaCAAAAGAAAACCCTTTGCCCGCTGTGCGGTAAATTAATACTCTCGCTAAAAGACCACATGTTGAGTCACAcgggggagaaaaaatatCGCTGCAAGTACTGCCCCAAGACCTGCGGTCGGAAAGGATCGCTGCGGCTGCACATGCAAGCCGTCCACCTGAAAAAGATTGTAAAGAGCTGTGAAATATGCGGCAAAGGCTTTACTTACGTGGAGTCGCACGAAGCGCACATGcgcGCCAAACACGGCTTCGGTGAACCATTTGAATGTACCATatgcaacattaaatttcGCCATAAAGGCGGTTTGCGGGGTCACAACAATCGCAAGCACAACGATGAAAGCAACTGTGAGTGCCCAACTTGTGGCATGAAATTTCTCGACAAgaAAGGATTACGAGCGCACAGCATAGTGCACTCGGACGAGCGACCGTTTGGCTGCCGCTATTGTCCAAAGATGTTCAAAACTGCTAAAACGCTGAAAAACCACGAAAACCTCCACGAAGGTGTAACATTTTCCTGTACGATGTGCGGAAAAAGCTATAAGCATCAATCGCTGCTATACGTGCACATGAAAAAATGTCATGACGAGGGTAAAAATGACAAATTGAAATTGGAAAATGAGTCTACGAAACTGATCGACTCCACGCTGACCGTGGACGATATCGAGCGATTTACCGGTGTGCGGatcTGCGAACAGGAACGATTGCCGTACGTCGTGTGCATCGATTGTAATAACAAGCTAAGGAAGTTCATCGCCTATCGTGCTTTCTGCACAAGCAATGATGTTCGGTTTAGGAAATGGTTTGCGGTAACTCTTTCGGACGATTTGAGCGACCCGGATCGGACTAGTTCATCGCTCAAAGCCCTCATAAAGGAGGAATTGGCCGCTGATCAACGCGAAACCACCAAACATTACAGTCCTATCGATGATTGTAACGATCAAGCGTTCGATAGTAAGCAGAAAGTTCAAGAAATTGAACAGGGCGAACAAAGGATAGAAGATGCTACTGCCCTAGAGGGTACGGACAATATCGCCATAGATGATGAGGATCTGGGTCTTGAGCATGTACTTTTGAGCGATGAGTTGACGCCTGATCCAATCGAGACAAGCAATACCCTGCCATCCAGCCACCAAAGCGAGCAGCAACGGAAGCAACGGCGAAGGGTGACAGCATCGCCCGCTGCCAAAGACAAACACGCAACACGGGACAGCCAGGAGCAGGACAGCAAAAAGCATGTACCGGCCAAGCAGCTGTGCCCGCTGTGTGGCAAACTGGTGCACTCCATGGCAGACCACATGCTGTCTCATACGAAGGAACCGAAGTTTTCCTGCCAGCACTGCCCGATGACGTGCAGCCGCAAATCGTACCTCAAGCTGCACGTGGACGCCGTGCACAAGAAGCGCATCATAAAGAGCTGCGAAATGTGCGACAAAGGGTTCAGCTATATCGAATCGTATGAGGCTCATATGCGATCGAAGCACAACTACGGAGAATCATTTGAATGTACCATatgcaacattaaatttcGCCATAAAGGCGGATTGCGGGGTCACAACAATCGCAAGCACAACGATCAAACCAACTGCTCCTGCGATATTTGTGGCATGAAGTTTCAGGACAAGAGAGGGCTACGCGCACATGGTAGGGTACATTCGGACGAGAAACCCTTTGCCTGCCAGTTCTGCCCGAAGCGCTTCAAGAGTCCAAACGCACACAGAACGCATGAGCTGATCCACAAGGGCGTTGTATTTCCGTGCACGATGTGCGATAAAACGTACACGTACAAATCGTTGCTCAATATGCACGTGAAAAAATGTCACATTAAGCAGGAGGAGGgtcgcATCGAGATGGCGATAATTTTACGCAATATCAGCAACATTTGTCGACTTTGTCTAAACGACGACGAGGTACTGTTTCCCGCCACGAATATCCTAGATGCAGGACTAACCAGCGAAGATGTGGAGCGGTGCACCGGAGTTCAGCTATTTGACGAGTCGAACATTTTCTACGCGATTTGCATCGAATGCCACAACAAGGTGCAAAAGTTTACAGCGTATCGAAGCTGCTGCATGAACAACGATGTGCGATTTCGTCGCCTGTATCCGATGATATTCGAGAAGCTGGTCTGGGACGAAGAAACGGGCCCGGAGGAGTGTTTGAAAGCGGACACCGTTGACCATAGCTACTGTGTGGAGTCGTACGAAAATCCACCGGAAGAGGAAAGCGTAACGGAAGAGGAAAGCGCTGCACCAGTTGATCTACCGGAAGAAATAGATCCAGAATATGAAGAGCTGGTAGAGCTGTATGCGGCTGACGACACCAAAGTTGATGTTGATGACATTATAGAAGAGATCGTACTCGAAACGAACGCCGACATCGAAATCATCCCTCAAGAGAGCGGTGAAGAAACATTCTTGCCAGAGTTGCCTCCGGTGCAGGAAGCAACGGTGGAGGAAGTGGAGCATCAGGAAGACAACGCGTGTGTAATCGAATCAAATGCATGCTTACAGGGAGTTGTAGAACTCAGCGAACCTAGCCAACAACAGCACTCCACAGACGAACCGCAGATTGCGCACCAAAGCACTGAAGAGGAGAGTGATTACGAGTGGATGGAAGCACCGAAGGCGGCTAAAGAAAGCACTGCCAAGGATGCCAAAGGAAGCAGACCCAAACAGCAGCTTTGTACGCTGTGCGGGAAGCTGGTTAGCTATCTGCGGGACCACATGATAACGCACACGAAGGAACAGAAGTACGCGTGCGACCGGTGCCCGTTCGTATCGAGCCGCAAGGCGAATTTAAAAACGCACGTGCAAAACGTACACCTCAAGCGGGTGATAAGGAGGTGTGAAAAATGTGACCGCGGTTTCAGCTACGTCGACTCGTACAACGCTCACATGCGCGCCAAACACAACCTGGGAGAGTATTTTGAGTGTAAAATATGTTCGAAGAAATTTCGCCACCGTGGCGGACTGAATGGCCACCTGAACCGCAAGCACAACGAGGAGAGCAACTGTACCTGTCCGGTTTGTGGATTCGTGTGCCAGGACAAAAAAGGGTTGAAGGACCATAGCAGAGTGCATTCCAACGAGAAGCCGTTTGTGTGCCGGCACTGTCCGAAGGCTTTCAAGAGCACGTACGCACGCCGAACGCACGAGCTGATCCACaagggtgttgttttttcgtgCACGGTGTGCGAAAAATCCTATCGCTACAAGTCGCAACTGGTGCTGCATTCGAAAAAACACAACGCGCAGCCAAATACGCAGCAGCAAGAAAATGAGCGATAA
- Protein Sequence
- MEAIVPNLNEICRLCLCEDIRFLIPASKLLDDSLSLQHIERFTGIRIPPNDCELYALCMECGNKLTTSVAFLVCCKNNDTVFRNLFDLPALDAAGEDRILVDFSTEVKQSPEIEVLEEACTEPEAQETQEVQELPHNTTTTVCTKPPDATEDDRVSSNFSSQLKKSPEIEVLQEPCTELEAKETRAVQSLSHNTTSTCTEPPSAAGEFTIDPNDFIIESLDSMIDDVIVHHDGGAESLDGIEHAVAEDEPPDDAGVYCYNTSSSDQRDERSAKQELSASVSSASQIERKPPLHIPTDLECSACEIKFVDEITFKRHYRRYHVSELQKSREHRKKRQLCVECGKMVLQLSAHRLTHTQEKQFSCPHCPMKMKSKGNICRHIEAVHLKKPAKTCETCGREFVHANMYKYHMLSVHGIGKAYECAICLKKFNALSSLKSHKQTAHEKRSAFECETCGKKFKRRHTLQMHIKQGHSNDKLYSCSLCPKRLKTLLGKQAHELAHSGAVFACTLCDKVFRYKCLLQGHVSQDHVKAEGREKLQKELIIQCLQTNTSASRCAMAAIPREINEVCRLCLCRDENILFPATKFIDSQLTLDDVERVAGVRIVEQESMRCVLCVDCNNKLRHIKAFKASCISNDETFRKWFTVADKDCSRDDTHPLKLNAAAQALNGAARETDQCNDSANEFDEATFFDNNIEVIKEEEIDDLAVKYIVQEMYEDMEVLTEDVVDFDVDDDDEDAEEFAEDMKTEGSQTSIDDFVTSDDPGEASVPYEPYERQPTTPNETFAPAIPADHQTVTAAASEETGKKKNPQKKTLCPLCGKLILSLKDHMLSHTGEKKYRCKYCPKTCGRKGSLRLHMQAVHLKKIVKSCEICGKGFTYVESHEAHMRAKHGFGEPFECTICNIKFRHKGGLRGHNNRKHNDESNCECPTCGMKFLDKKGLRAHSIVHSDERPFGCRYCPKMFKTAKTLKNHENLHEGVTFSCTMCGKSYKHQSLLYVHMKKCHDEGKNDKLKLENESTKLIDSTLTVDDIERFTGVRICEQERLPYVVCIDCNNKLRKFIAYRAFCTSNDVRFRKWFAVTLSDDLSDPDRTSSSLKALIKEELAADQRETTKHYSPIDDCNDQAFDSKQKVQEIEQGEQRIEDATALEGTDNIAIDDEDLGLEHVLLSDELTPDPIETSNTLPSSHQSEQQRKQRRRVTASPAAKDKHATRDSQEQDSKKHVPAKQLCPLCGKLVHSMADHMLSHTKEPKFSCQHCPMTCSRKSYLKLHVDAVHKKRIIKSCEMCDKGFSYIESYEAHMRSKHNYGESFECTICNIKFRHKGGLRGHNNRKHNDQTNCSCDICGMKFQDKRGLRAHGRVHSDEKPFACQFCPKRFKSPNAHRTHELIHKGVVFPCTMCDKTYTYKSLLNMHVKKCHIKQEEGRIEMAIILRNISNICRLCLNDDEVLFPATNILDAGLTSEDVERCTGVQLFDESNIFYAICIECHNKVQKFTAYRSCCMNNDVRFRRLYPMIFEKLVWDEETGPEECLKADTVDHSYCVESYENPPEEESVTEEESAAPVDLPEEIDPEYEELVELYAADDTKVDVDDIIEEIVLETNADIEIIPQESGEETFLPELPPVQEATVEEVEHQEDNACVIESNACLQGVVELSEPSQQQHSTDEPQIAHQSTEEESDYEWMEAPKAAKESTAKDAKGSRPKQQLCTLCGKLVSYLRDHMITHTKEQKYACDRCPFVSSRKANLKTHVQNVHLKRVIRRCEKCDRGFSYVDSYNAHMRAKHNLGEYFECKICSKKFRHRGGLNGHLNRKHNEESNCTCPVCGFVCQDKKGLKDHSRVHSNEKPFVCRHCPKAFKSTYARRTHELIHKGVVFSCTVCEKSYRYKSQLVLHSKKHNAQPNTQQQENER
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -