Basic Information

Insect: Anopheles arabiensis
Gene Symbol: tbpl1
Assembly: GCA_016920715.1
Location: NC:109676345-109686879[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 6.1 2.9e+02 1.7 0.1 3 23 268 291 266 291 0.79

2 21 5.1e-05 0.0025 17.7 0.4 2 23 299 320 298 320 0.96

3 21 9.7 4.6e+02 1.1 0.6 12 23 376 388 374 388 0.83

4 21 0.0078 0.37 10.8 0.6 2 23 396 417 395 417 0.98

5 21 0.21 10 6.3 0.1 9 23 505 520 503 520 0.90

6 21 0.017 0.8 9.8 0.9 2 23 528 549 527 549 0.96

7 21 3.9e-05 0.0019 18.0 0.3 1 23 580 603 580 603 0.96

8 21 0.011 0.53 10.3 0.5 3 23 610 630 608 630 0.95

9 21 2e-06 9.4e-05 22.1 0.4 1 23 636 658 636 658 0.96

10 21 0.0012 0.057 13.4 0.3 2 23 691 713 690 713 0.96

11 21 7.8e-05 0.0037 17.1 2.2 2 20 720 738 720 740 0.94

12 21 0.00017 0.0079 16.1 2.7 3 23 749 769 747 769 0.97

13 21 0.13 6.1 7.0 0.0 8 23 1484 1500 1467 1500 0.73

14 21 0.0001 0.0049 16.7 0.7 2 23 1509 1530 1508 1530 0.96

15 21 0.00014 0.0065 16.3 2.0 1 23 1561 1584 1561 1584 0.97

16 21 0.076 3.6 7.7 0.4 2 23 1590 1611 1589 1611 0.82

17 21 3e-05 0.0014 18.4 1.1 1 23 1615 1637 1615 1637 0.97

18 21 0.00026 0.012 15.5 0.6 2 23 1648 1670 1648 1670 0.97

19 21 2.2e-05 0.0011 18.8 0.5 3 20 1678 1695 1677 1697 0.93

20 21 5.4e-05 0.0026 17.6 0.7 1 23 1704 1726 1704 1726 0.98

21 21 1.4e-05 0.00069 19.4 1.7 1 23 1732 1755 1732 1755 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	6.1	2.9e+02	1.7	0.1	3	23	268	291	266	291	0.79
2	21	5.1e-05	0.0025	17.7	0.4	2	23	299	320	298	320	0.96
3	21	9.7	4.6e+02	1.1	0.6	12	23	376	388	374	388	0.83
4	21	0.0078	0.37	10.8	0.6	2	23	396	417	395	417	0.98
5	21	0.21	10	6.3	0.1	9	23	505	520	503	520	0.90
6	21	0.017	0.8	9.8	0.9	2	23	528	549	527	549	0.96
7	21	3.9e-05	0.0019	18.0	0.3	1	23	580	603	580	603	0.96
8	21	0.011	0.53	10.3	0.5	3	23	610	630	608	630	0.95
9	21	2e-06	9.4e-05	22.1	0.4	1	23	636	658	636	658	0.96
10	21	0.0012	0.057	13.4	0.3	2	23	691	713	690	713	0.96
11	21	7.8e-05	0.0037	17.1	2.2	2	20	720	738	720	740	0.94
12	21	0.00017	0.0079	16.1	2.7	3	23	749	769	747	769	0.97
13	21	0.13	6.1	7.0	0.0	8	23	1484	1500	1467	1500	0.73
14	21	0.0001	0.0049	16.7	0.7	2	23	1509	1530	1508	1530	0.96
15	21	0.00014	0.0065	16.3	2.0	1	23	1561	1584	1561	1584	0.97
16	21	0.076	3.6	7.7	0.4	2	23	1590	1611	1589	1611	0.82
17	21	3e-05	0.0014	18.4	1.1	1	23	1615	1637	1615	1637	0.97
18	21	0.00026	0.012	15.5	0.6	2	23	1648	1670	1648	1670	0.97
19	21	2.2e-05	0.0011	18.8	0.5	3	20	1678	1695	1677	1697	0.93
20	21	5.4e-05	0.0026	17.6	0.7	1	23	1704	1726	1704	1726	0.98
21	21	1.4e-05	0.00069	19.4	1.7	1	23	1732	1755	1732	1755	0.97

Sequence Information

Coding Sequence: ATGGATGCAGCGGCGGCTGtagcaccaccatcagcagcagcagcagcagcaccgccaccaccactaccaccgctGCCGCTAGCctcggctgcagcagcagcaccaccaccaccgaacaGTGTTTACGATGTCATCAATCAAAAGGAATGCGGACTGTGTCTCACGCTCCGGGCGGAGCAGATCTGCTTCGACATGTTCATGCCGCGGGAGGACGACCCGAAGGAGATGCCGTATCTGGTGTGGAAGCACGTCGGGCTGCAGTTTCCGCAGGAGGCAGGCAAACACTACGTCTGCCGGGACTGCGGGTTCGCGGTGTACGAGTTTAACCGATTCTACTTGATGGTGCAGAACGTACACCAGGAacggcaggcagcagcagcggcagcagtacTGCAACCGAAGCAAGAGCCGCCTATGCAGGAGCAGGTACAATATAATGCTGagcaggcggcggcggcggcggccgtgGTGGAAGGTGTCAATCAGAACGGTCATCATGGAGGCGAGCAAAAGTTTGACCCGTCGCCGCTGGTGGACGGGCCCGTACCGTTGCTGTCCGATGTTCCGGATTATGGGATGAATCACGAAGTGAACGGAATGCTACCATCCGGCGGATCCGGGGTAACGGCTGTCGGGGGCAACGGTACAGGGGCAGAGTGTCCGTCGGTGTACACGTCGCAGCACAACGATACGGAACCGGAAAGCAGCCGAATCCggccggtcacgggcaacacACCGAGCAGCCGGAAGCGCCGGAATCAAGAGATGGACGATGAGATTATCGACTTTTACAAGCTGGTCTGTGACGTGTGTGAGGAACGCATCGAGTACGGCACGATGAAGGAGCTGAACCAGCACATGAAGCTGATGCACGGGGAGGAGACGGGCCGGGTCAGCTGTCCGCAGTGTGGCAAGATGTTCCGCACGCGGGGGAAGCTGCTGGAGCACAAGAGCGTGCACCAGCGACAGGACGCCACGTCCGAGGACGACGCGGAGAAGCTGCAGTCCGAGCAGATGGACAAGGAGATACTGGAGTTTTACAAGCGCATCAGCTGCGATGTGTGCGACACGGCGGCCAGTGCTGCTGCCGGGGCCGGTCCACAGGCCAGCGCGATGCTGTACGCGACGGTGAAGGAGCTAAACCACCACATGCGGCTGGTGCACGGGCAGCAGGCCGGTACGGTAAAGTGTCCACTGTGTGAGAAGAAGATCCGTACGCGCCCGAAGCTGCTCGAGCACAAGCGCATGCATCAGCCAAACGcgctgctggaggaggatTCCGGCAAGTCGGGCAACCCGGGTGGCGAGCCGGGGCCCGAGCTGACCGAGGAGCAGAAGCAGACGCTAGATAGAGAAATATTCGATTTCTACAAACCCATCATATGTGAGATTTGCGATCCGGAAAAGGTCGCTGTGGCTGTCGCGGTGGCCGGCCCCGGCGGTGACCCGGGCGGTGTTGCCGCGGGAGCGGGCCAGTCggaagcggcagcagcagcaacgacccAGGAGGAGGAGTACCGGTCGCTGAAGCAGCTGAACCAGCACATGCGGACGGTGCACGGGCTCGAGTCGGGCACGGTCAAGTGTCAGCTGTGCGCGAAAAAGTTTCGCTCGCGCGTCAAGCTGGTCGAGCATAAGGATATGCACGAGAATCCGGAGCGGTTCCGGTGCGGCGTGTGCCAGGAGGTGCACCAGAACCTGGAGGAGCACATGCAGAACAAGCACCAGGAGTGGGAGTTTGCCTGCGAGGAGTGCGGCAAGCGGTTTCCTTTCAAGAACAGACTCACTGCCCACATGGCCAAGGTGCACATGAAGAAGGACATTATCTGTGAGGAATGTAACAAACCATTTACAAAGTTCAGCATCGAGAAACACAAGAAAACGGTCCACGGCCACGGTGGGACGTTCATCTGTGAAAACTGCCCGAAAACGTTCAAGACGCGCGTCTCGCTCGAACGACACATGGAGGGCCACAACAacggggagcagcagcagcagcagcagctgcagcaaccgCAACCGCTCCCACTGCCGCTACCGCAGCATCAACCGAGCTCTGCCCCGACCGTCAGTTGCTCCCTGTGCAACTCCGTCCTGAAGGACGAGTACAACCTGAAGGCCCACATGAAGCGCATCCACGCGGAGCAGACGCCGGCGACGTGCAACACGTGCGGCAAGACGTTCAAATCGAAGCACAGTCTCAACACGCACACCGCGAACGTGTGCACGACCCGGCTCTTTGGCTGCACGACCTGCGGCAAGCAGTTTAAGAAGCGGACAAAGTTGAAACAACACATGACGATTCACCCACGCGGCGCCGACTATGTTGGTGGCAAAGCCACGGTACTCGGTGTGAATTCGGCCACCGGACATAATGAGGTGGTGAGCGGTGCGAACGGGTTCCATCTACGGCAACatccgcaacagcagcagcagcagcaacagcagtcgaGCACTTCCGGTGTTGTTAGGCTTGCGAAGGGCAGCACTAGCAGCGTGATATCGCTTCCGAGCGACCACCAGTACCACCAGTCCATCGCAGGCGGAATGATTAATCACAGTTCCTTGATGTTCGCGACAACAAcgaccaccaaccaccaacagcagctgTCGGTTTTATCGAACGCATCACCAGTAGGCGACGGAGCAATCGGCGAAAAGAAGGCAGGCGCTAAGATCGGTGACAGTACCAGCTtgacaaccaccaccacaggcaacagcagcagcatcatcctGGCCAAAACGAGCCCGGACAATGAACCGCAGGAGGAGCAGCCGGAGATTGACATCGTGATCAACAACGTGGTCTGCTCGTTCAGCGTACGCTGTCATCTGAATCTGCACGACATCGCCCGCCATGGGCACAATGTCGAGTTCCGGAGGGAGCACGGGATGGTAACGATGAAGCTGCGCCGCCCCTACACGACTGCTTCGATTTGGTCGTCCGGAAAAATCACTTGCACCGGTGCTACATCAGAGCATCAGGCAAAAATAGCGGCACGACGCTACTCACGTTGCCTTCAGAAGTTAGGATTTAATGTTAGATTTAGGAACTTTCGTATCGTGAATGTACTCGGCACCTGCAGCATGCCGTTCGGCATCATGATTGTCAACTTCTCGGAGAAGTACAAAAAGGATGCCAGCTACGAGCCGGAGCTGCATCCGGGCGTCACCTACAAGCTGTACTCGCCGAAAGCGACCCTGAAAATATTCTCAACCGGAAGCATTACCGTCACCGCGGCTAGTGTGGCCTTTGTGCAAGCGGCAATTGAGCAAATATTCCCGCTCGTGTACGAGTTTCGCAAGAAGCGGACGCCGATCGAGAAGCAGGCGATGGCGAAGCAGCAGCCACCGCCGGACTTTGACCCGCACGATGTCGACCATCTGATCGAGGAGGACCGCGAGGGCGCGCTGGCGGAAGCGGAGGAGGGCCTCACGTACTGGAACGGCACGGCCGACGAACCGACGATGCAGCAGCCCGAGGAGGAGCAGCCGGACGACGAGCTCGAAACGTTCGGCGACGATGAAGACGTCCGCACGCGTAACAACACCAAAGCAATACACAAAATCAATAGTATTAGGCAGAACGGTAAGAAGCGCCGAATGCGCCAGCTGCGCCCATCGGGCCGGGCTGTAAACGACGGGGACAGCATGTCCGACGACGATCTGTGCTCCCTCCCGATTTGGGGgaaattgtttgcattttctcgCTGCAATAGATATCGCCAGCCCGTGTTCGCCATGGCGTCAGTGAAGGTGGAAAATAGTTCCAGGATCGTTGCCAACTCTACACGGGATCATCCACAGTGCGATGTGTGCCTGCGCTGGGAAAGTGTTTGCTTCGGCAGATCGGATCCCATCTTCATTGGGAAAGATGTGTTGGCCATGGTAACACAGTATCTCGACATGAACATCACCCTAACACTCGTCTGCGAACGCTGCTGGAGTATATTGAAGGAGTTCGATGAGTTCTACCGGATGGTCAGCGAGCAGCACACCAGCAAAGCGGATCTGCGGCCCCCAGACCGGAAGGAAGCTGACCCGGTCGAACAGCGCGTGGAGGGAGTCGTTTATGGAATGGAATTTGTCGACATAAAGTACGAACCGCTGGGTGAAGATGCGAATGTAACGAtaaaagaggaagaggaggaggaggaagcggaGGAGCATGAGAGAGAACCACTTCCGGACAGTGACGACTGTGACAAGCTGTTGCCCAGCCAGTCGATGGAGTTGGACGATGAGGAACGCCTGGCGGATGACGATACGAACTCGTTGTCCTCCGACGATAGTGACGATTCCTCGGTGCCGGATCGGGTGAAGCGCGGCGGCAAAGCATCGGCCATCGGCAAGAAAGAGCCCAAGGTGGATAAGGAGATATTGGAGTTTTACCAGCGGCTGGTGTGCGAGATTTGTGATGCGGAGCGGATGCTGGCCGGCGAACCGTCGATCGAGTACAGCAATCTGAGGGAGCTGAACAAGCACATGCGAAAGGTGCACGAGCAGGTCGGCGCTACGCGCATCAAGTGTCCGATGTGCGACAAAAAGTTCCGCTATCGGGCGAAGCTGCTCGAGCATCGGGACATGCATCAGAACCCGGACCGGTTCCGGTGCGTGGTGTGCGAGGAGGTGCACCAGAACATGGCGGAGCACATGAAGAACAAGCACCAGGAGCGCACGTACTGCTGCGAGGAGTGTGGCAAGCGGTTCCCGTTCAAGGCTCGGCTTACGGCGCACGTGAAGAAAATGCACACCTCCAAGGATGTCGTCTGTGACCAGTGTCAGAAAAGCTTCAGCAGATACACGATCGAGGACCACAAGCGGGCAGTTCACGAATCGCGCTACATCTGCGAACACTGTCCGCGCACGTTCAAGTCGCGTCTTGCCCTCACGCAACACATGGAGGAACACGTGGAGGGATTGCGGAAGACGGTTTCCGCCACCTGCGAAAAGTGTGGCGTAGTGCTGCGGGACAAGTACACGCTGCAGACGCACATCAAGCGCATGCACACGGAACATCCGCCCGCCAGCTGCGGCACGTGCGGGAAGGTGTTCAAGTCGAAGCACAATCTCAACGCGCACCTGGCCAACGTGTGCACGGAGCGTTCGTTCCCGTGCCCGATCTGTGCGAAGCAGTTTAAGAAGAAGATTAAGCTGACCGAACACATGACGACGCACACGAAGAGTGTGCTCTATCAGTGTCCGTACTGTCCGAAGACGTTCAGCTTCGAGACGCAGCTGTACACGCACCGGAAGCAGGCGCACTACGAGCAGTGGCTGGAGATGCAGCGGAAGCGCAAGGAGGGTGTACGGTTTAAGGTTAACCGCATCACGGATATGCCCTCTACCTGA
Protein Sequence: MDAAAAVAPPSAAAAAAPPPPLPPLPLASAAAAAPPPPNSVYDVINQKECGLCLTLRAEQICFDMFMPREDDPKEMPYLVWKHVGLQFPQEAGKHYVCRDCGFAVYEFNRFYLMVQNVHQERQAAAAAAVLQPKQEPPMQEQVQYNAEQAAAAAAVVEGVNQNGHHGGEQKFDPSPLVDGPVPLLSDVPDYGMNHEVNGMLPSGGSGVTAVGGNGTGAECPSVYTSQHNDTEPESSRIRPVTGNTPSSRKRRNQEMDDEIIDFYKLVCDVCEERIEYGTMKELNQHMKLMHGEETGRVSCPQCGKMFRTRGKLLEHKSVHQRQDATSEDDAEKLQSEQMDKEILEFYKRISCDVCDTAASAAAGAGPQASAMLYATVKELNHHMRLVHGQQAGTVKCPLCEKKIRTRPKLLEHKRMHQPNALLEEDSGKSGNPGGEPGPELTEEQKQTLDREIFDFYKPIICEICDPEKVAVAVAVAGPGGDPGGVAAGAGQSEAAAAATTQEEEYRSLKQLNQHMRTVHGLESGTVKCQLCAKKFRSRVKLVEHKDMHENPERFRCGVCQEVHQNLEEHMQNKHQEWEFACEECGKRFPFKNRLTAHMAKVHMKKDIICEECNKPFTKFSIEKHKKTVHGHGGTFICENCPKTFKTRVSLERHMEGHNNGEQQQQQQLQQPQPLPLPLPQHQPSSAPTVSCSLCNSVLKDEYNLKAHMKRIHAEQTPATCNTCGKTFKSKHSLNTHTANVCTTRLFGCTTCGKQFKKRTKLKQHMTIHPRGADYVGGKATVLGVNSATGHNEVVSGANGFHLRQHPQQQQQQQQQSSTSGVVRLAKGSTSSVISLPSDHQYHQSIAGGMINHSSLMFATTTTTNHQQQLSVLSNASPVGDGAIGEKKAGAKIGDSTSLTTTTTGNSSSIILAKTSPDNEPQEEQPEIDIVINNVVCSFSVRCHLNLHDIARHGHNVEFRREHGMVTMKLRRPYTTASIWSSGKITCTGATSEHQAKIAARRYSRCLQKLGFNVRFRNFRIVNVLGTCSMPFGIMIVNFSEKYKKDASYEPELHPGVTYKLYSPKATLKIFSTGSITVTAASVAFVQAAIEQIFPLVYEFRKKRTPIEKQAMAKQQPPPDFDPHDVDHLIEEDREGALAEAEEGLTYWNGTADEPTMQQPEEEQPDDELETFGDDEDVRTRNNTKAIHKINSIRQNGKKRRMRQLRPSGRAVNDGDSMSDDDLCSLPIWGKLFAFSRCNRYRQPVFAMASVKVENSSRIVANSTRDHPQCDVCLRWESVCFGRSDPIFIGKDVLAMVTQYLDMNITLTLVCERCWSILKEFDEFYRMVSEQHTSKADLRPPDRKEADPVEQRVEGVVYGMEFVDIKYEPLGEDANVTIKEEEEEEEAEEHEREPLPDSDDCDKLLPSQSMELDDEERLADDDTNSLSSDDSDDSSVPDRVKRGGKASAIGKKEPKVDKEILEFYQRLVCEICDAERMLAGEPSIEYSNLRELNKHMRKVHEQVGATRIKCPMCDKKFRYRAKLLEHRDMHQNPDRFRCVVCEEVHQNMAEHMKNKHQERTYCCEECGKRFPFKARLTAHVKKMHTSKDVVCDQCQKSFSRYTIEDHKRAVHESRYICEHCPRTFKSRLALTQHMEEHVEGLRKTVSATCEKCGVVLRDKYTLQTHIKRMHTEHPPASCGTCGKVFKSKHNLNAHLANVCTERSFPCPICAKQFKKKIKLTEHMTTHTKSVLYQCPYCPKTFSFETQLYTHRKQAHYEQWLEMQRKRKEGVRFKVNRITDMPST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -