Aara008330.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles arabiensis
Gene Symbol
-
Assembly
GCA_016920715.1
Location
NC:17715065-17724187[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 30 0.037 1.8 8.7 5.6 1 20 344 363 344 367 0.95
2 30 0.0015 0.071 13.1 0.8 2 23 375 396 374 396 0.97
3 30 1.5e-05 0.00071 19.4 0.3 1 23 404 426 404 426 0.98
4 30 0.00088 0.042 13.8 5.6 1 23 432 454 432 454 0.98
5 30 3.1e-06 0.00015 21.5 3.7 1 23 460 483 460 483 0.97
6 30 1.2 56 4.0 4.3 1 23 508 532 508 532 0.98
7 30 0.00014 0.0067 16.3 1.1 2 23 537 559 536 559 0.94
8 30 4.4 2.1e+02 2.2 1.3 2 23 917 938 916 938 0.93
9 30 5.3 2.6e+02 1.9 0.2 12 23 968 979 964 979 0.86
10 30 0.05 2.4 8.3 5.1 2 23 984 1006 983 1006 0.95
11 30 0.062 3 8.0 0.4 1 23 1015 1037 1015 1037 0.98
12 30 6e-05 0.0029 17.5 0.7 1 23 1045 1067 1045 1067 0.98
13 30 2.1e-05 0.001 18.9 0.8 1 23 1073 1095 1073 1095 0.97
14 30 1.1e-05 0.00054 19.7 2.2 1 23 1101 1123 1101 1123 0.98
15 30 1.8e-05 0.00086 19.1 4.1 1 23 1168 1191 1168 1191 0.97
16 30 0.022 1.1 9.4 0.8 1 23 1197 1219 1197 1219 0.97
17 30 3.7e-06 0.00018 21.3 1.0 1 23 1225 1247 1225 1247 0.98
18 30 0.00099 0.048 13.6 3.4 1 23 1253 1277 1253 1277 0.95
19 30 0.71 34 4.7 0.1 2 23 1689 1710 1688 1710 0.95
20 30 0.33 16 5.7 0.4 1 23 1716 1744 1716 1745 0.93
21 30 0.0018 0.086 12.8 1.8 3 23 1750 1770 1748 1770 0.97
22 30 0.00025 0.012 15.5 2.5 2 23 1776 1797 1775 1797 0.97
23 30 0.00033 0.016 15.1 0.5 1 23 1805 1827 1805 1827 0.99
24 30 0.0039 0.19 11.8 4.6 3 23 1835 1855 1833 1855 0.97
25 30 1.2 57 3.9 1.0 2 14 1862 1874 1861 1884 0.76
26 30 1.8 85 3.4 0.1 2 23 1913 1937 1912 1937 0.96
27 30 0.00033 0.016 15.1 1.3 1 23 1941 1963 1941 1963 0.97
28 30 4.4e-06 0.00021 21.0 1.0 1 23 1969 1991 1969 1991 0.99
29 30 6.7e-07 3.2e-05 23.6 0.9 1 23 1997 2019 1997 2019 0.98
30 30 0.00029 0.014 15.3 3.4 1 23 2025 2048 2025 2048 0.96

Sequence Information

Coding Sequence
ATGTCTGCGGAATGCTCTGACGCGTCCACCGACCCGAGGCTGCTGCAGTATCGGGACCTGTTTTGTCGAATATGCCTCCAGTACAGCAAAGGGGCGCTGATCCCGATTGGGGCGGAGATAAAGAAAACCACCCTGCTGGACATGTTTATACAGCTCACCACATTTGAGCTGGATCACAATGACGCGTTTCCAAGGTTCATGTGCGAGCAGTGCGTCAGCAAGCTGACGCTGGCGTACAGCATCCGGGAGGAGTTCATCTCGCAGACCGATCTGCTGCTGAAGCTGGTGGTGCAGAAGCAAATCATTAAGTACTACGAGCAATTTCCGCTGGAACCGAAGGTTCAGGCACCGCCCAAGGTAATACAGCCGAGCGTCCATGCACCGTTCCGGGAGCTAAAGCCCACCCGGGTGGCGAAGCCAACCGGCGGAGTGCCGGTGGTGAAACCGCAGCAGATGTTAATTCAGGAAAGCATCAAAGATGAAACGGTAGAGGAATTGGATGTGGATGAGGAGGTAATTCAGGAGGAAATCCTTaacgacaccaccaccaacaccgtgcCGCTGGACGAGTCCAGTCTCGCGGTTGATTTCAAAGACGACTGGGATTCGTCCAGCACGGCCACCTCGCTCGATGAGGATGACTGGAGCTACACGCTCAACCCGATCACGCCCCAGAAGCTGGAGGAGCTGAATGCGGCCCGGCCCGTGCGGATGAAGAACCCGAGCGGCTCGCGCAAGCGCCCGAAACCGGCGGAGGAGAAACAGGACAAGAAGGAGCGGAAAAACCAAtactccaccaccacctgctACATCTGTGATACGCACCACGAGTCGATCGCGCAGCGGGACGACCACTTCCGCAACCACATCCACATGCTGCCGTACGAGTGCACGGAGTGTTTGGCCGATCCGCCCCCGGAGGACGCCGATTCGCCGCGGAAGGACCAGCCAGCGGCGGAACATCCCACCCACATCGTGCTGCGCAGCGTCATCCAGCTGAACAGCCACATGATGATGCACGGTTTTCCGCACAAGTGTGAGCACTGCTACCGGCGCTTCACGACCGTGTATCTGCTGAATCACCACCTGTGGAACTACCACCAGCACTCGAAGGAGGGGCTGACGTGCGAGTGGTGCGGCAAGCGGTACTACTCCCGTCGCCCGTTCCAGGAGCACGTGCGGCGCCACAAGCACTCCGTCACGGAGCGGTTCAAGTGCACGACGTGCGGGCGTGCGTTCGGCTCGAACGCGCTGCTGCGCCGCCACGAGATGGTGCACACGGGCGAGCGCAGCCACAAGTGCACCTACTGTCCGCGCCTGTTCAGCCGCCGGTGCAATCTGCTCGACCATCTGCGGCTGCACACGGGCGAACGGTGCCACAAGTGCAGCGAGTGTCCGCAATCGTTCAACACGAAATCGTCGCTCGAGAAGCACCAGCGCAACTACCACAGCGATCTGGCGGTGGTGCCGCCTCGGGGCGACCGCAACATCTACACGCTCCAGTCGGACGGGTCGCGGCTGTACCGGTGCAAGCACGAGGGCTGCACGTTCACCAGCACCTCGAGCACGACGATGACGCAGCACCGGTTGCGCCACAACAAGCCGTGCGTTTGCGAGGAGTGCGGCCAGCGCTTCGTCTCGCCCAAGTACGTGCGCAAGCACATGAACCTGATGCATTCCGGCAAGCCGCGCAAACCGCAGGGTAAGGGAGGCGCCGGCGGTGGTACGAAGAAGGTGAAGGAGGAAATTTCCGACGCGAGCAGCGCCACCATCCTGCCCGCGGACAACACGACGGAGCTGATCAGTGCGGACGAATCGCTGCTGGAAACGaagctggaggaggaggaggagataCAGCCGGACGATGAGGCGTGGGTCAAGATGAAGGACGGCATCATACGCACCGAGTGGAACGCGGGTGATCTGAACGTGGTGCGCGAGTACGTCGTCGAGTTTGTGGAGGATTCGAAGGAGATTGAAATAACCTTGCACACCTTTGACAGCTGCACTGTTTCGgcaatgtttgtttacaaaacaatGGAGCAGCTGCAGCGCGAAGATGCTGCTACCACGTCCTGTCCAATGGAGTCGTACTCGACCGCACCGCAGACGGCCGTCCTGCAACGCTTCTGCCGACTGTGCATGCGAGAGTTCCCCTTTCTGCTGCCGTTCAATGCTACGCTCAAAGAAATCGCGCTAGCCGACATGCTGGAACGACTGCTGGGTTCGTTCAAGCTAAAGCAAGCGCCCAATCTGCCGAACGGCGTCTGCTCGCACTGTGTCGCGAAGCTGGACTACGCGTACCACGTACAGAAGGAGTTGGTGCGGAACGAGCAGCGCTTGCGGCATTTCCAGCAGGAGGGAAATTTGTTGCagaaattgtttgaatatCAAGCTAACATTACAGTGACCAAAGAGGATGGGGGCGGCGATCGAATGGTGGCGGGGTATGGCAGTGGACTGCTGCCGGAGACGATCCAGCTAGATCCGAAGCAGGACGTACCGGATATGGCCGATGCGGAGCAGCGCGCGGCAGCTGCGTACAAAACGCTGATACCCCCGGGCGGCTGGGTTGTAATGGAGTGCGATTGTCCGGAGAAATCGATGGCCGCATCCACCCGGCGAGCTCCGCGGTCCATGAAACCCGCGCGTCCGCAGCAGCGAACTTTGCGCAATCGCCACGTGCTCCGGCAAGCAATTGATGCAGAAAATCCAACCGCTTTAAATGCAACTGCTATTGATCCCTGCAAATGCTACATATGTAATACCGTGCTGGAGTCGGAAGAAGACTGTCGGGCTCATTTGGCCGTGCATGTGGACATGTTGCCGCACGTTTGCCCCGAGTGTAGCACGCCGAATGCGTCGGAGGAGGATGACGACGCGCCGAGTACCCCAATCACCTCGCTGGCAATGTTACAGCGCCACTACCGCATGCACTCCTACCCACTGAAATGTCCGCACTGTCCGCAACGGTTCCGGAAGCACACATCCGTGTACACGCATGTGCGCTATCGGCACGAAATGTTCGACAATCCAGAGGGTTTCACGTGTGATGTGTGCGGCGTTACGATGCAGTACCGTCCCTCCTTCATGTACCACATGCGCATCCACTACCACGAACAGATGGGCACGTTCCGGTGCCAGTACTGTGATCGTGTGTTTGGAACACGGGCCCGCCTAGAgcgtcacgaacgggcacacaCGGGCGAGCGACCGTTCGCTTGCCATCTGTGCCCGAAAACGTTTGTGCACGCGGGCCAGCTGGCAACGCACATCGCGCGGCACAATAACGAGCGCGGCCACCGGTGCTCGCAGTGCGGCAAAGCGTTCTACAGCAAAGCGATGCTGCGGCAGCACCTGGAAACGCACGAAACGCACGAAACGCGCAAAGCGAGCAACGCGGCGAAAGTGCGCCAACGGCCCTGCGCGTATGCGGGCTGTACGCACGTGGCGCGCACGTATCAGGCGTACTACATGCACCGGCtgcggcacgagatggcgcACCGGTGTGAGGAGTGTGGCCGGCGGTTTGCTCGAGCGTGCGAGCTGAGACGGCACCGGCGCATCTATCACTCCTCGGAACATCCGTTTCGGTGTGAGCCGTGCGGCAAAACGTTCCTTAGCTCGCAGAGCTACCGCGAGCACATGGACTCGCACGCCAATGTGCGCCGGTTCGAGTGCGAAGTGTGCGACAAAAAGTTTGTGCGCCGGCGCAACCTGGTCAACCATCGGATGTCGCACACGAACCAGCGGCCGTATCGGTGCGAGTATTGTGACAGTACCACGTTCAAGTATAAGAGCGACTTGAACCGGCACCGGAAGGACAAGCATGGCCAGGCGGAGCACGGCGAGCAGACGTCGGCGTTGGCGCAAGAGGACGAAGACGGAGCGGACGGGGAAAAGATTGTGCTGATGAATGCGGACGATCCCATCATGGATGTGATACTGGAGGAAAGTGCTCCGCAGGGCATACTGATCAACGAGAACATTGAGCTGGACGGGACATACGGGGAGGAAATTGAGACGGTCGAAGAGTCGATCGTCGTTGAGCAGCCGATCGTTAGCATCGGTATCGATGAGGTGACCAAGGAGGAGTACATAATAGAGTACATAAACCATGTCACGTCCGACGCGTTTTGTCGAATATGTTTGCTGAAGCGGCCCCACCTGAAGTCGCTGATGGAGCGGGTCGATGGCGTGATGATACCGGAAATGCTGTACAAAGTGTGCGGCCGCCAGATCGAGGTGCAGGAGGGCTACCCGCGCAGCATCTGCCAACGGTGTCTGTGCCAGTTGGACTGTGCGTTTAAATTTTTGAACGAGTTCCACCAGCAGGACGAACGTTTGCGCAGCTTCTACTGGAGCGGTTCCGTGGTGAAACGGCTGCAGGAATACCAGAAGGAAGGGAGTGAAACGGTAGAAAAACGGTTTGCCGAACTGGTCACCCGTAATGCGAAAATGCTGAGCCCGCCAACTAAGCACATGTGCCACCGGGAGACGAACACCAGCCAACGCCCCAAACTGGTCGATGCTAGTACGCTGACAGACAAGGAGGCGGTGGCGGATCTAGCGCTGGTCAAAACGGAGGACGGAAGCGTAGTGTCCGACGATTTGGTGGTGGAGGACGAGGAAGGAGTGTATCTCGAGTATGCAGACGATTTCGATGCATCCATCAAGGACGAGCAGCTGGTGTCGATGAAAATCGATGTGCTGCAATCGGGCGACGAGGCGGAATCGGACGCCGAACCCAAGGAGCGCAGGAAGCGAGCTCCACATACGGCCACCAAAAGCACCCCGTCGTCGCGTTGGTCGACTCGGACAAGCCAACCTTTGCCGACGAAGCAGCAGGAAGACAGCGATACGGATGATCCggctacggaggaagatttcAAGGAGCTGTTCGAGGAAAGCGAACCAGACACTGTGTTAGAGATCgacgaggatgaggaggacgaTGATTTTGACgaagaggatgaggaggaggatgaagaGGAAGATGACGAGACTGAGGAGGGGAAGCACATGGTAGAGGAGCAGACGCCGCCGGTGCAGCTCGATCCGCTGCGCTGCTACATCTGCGACCGAAACGAGGAATCGAAAGCGATGCTGGAGCAACATCTCGATATGCACAGCCTGATGCTGCCGTACGAATGTAGAATTTGCCAGGTGGAGGGTGGACCCGCCCGCACGCTCAAAACCATCTCCTCCCTACAGAACCACTTCCGCTCGCACCACTACCCGTTCGGGTGCGGCACTTGCGGCAAGCGGTTCCTGCGCAAAGCGCACCTGATGACGCACATGGACAGCCACAACGAGGAGCACCTGGAGTGTGGCGAGTGCGGGCGACAGTTTACGCACCGCAAAACGTGGCAGAACCACCTGAAGCGCCACGTGGCCTTGCGGACTGGCGCGTTCAAGTGCGGCACCTGCGACCGGGCGTTCGGCAACCGGGCCCGGTTGGATCGGCACGTGCGCTCGCACACCGGCGAGCGGCCGTTCGGGTGCAAGTACTGCGACAAGCGGTTCTACgaccgccaccagcagcagcgccacaCCGAGCGGCACTTCCGCGACCAGGAGTGCAGCTGCGAGATTTGTGGCGAAACGTTCCCGGGCGCCAAGAAGCGCGACCAGCACAAGGTCGAGCAGCATCTGCACGGCCCGGAGCTGGAGGCGTTTTTGGCGCGCAAATCCAGACAGCGGTCGTACAAGAAGCCGGCCGTACTGAAGGATAAGAAGTGCCCGTTCGCGGGGTGCGATTACGTCGCCAACACGTACGGCGCGATGTACGTGCACAAGCGCTCCAAGCATCAGCCGGTGCACAAGTGCGAGCTGTGCAACAAATCGTACGCCTTCCTCAACCAGCTGCGGGTGCACATGGCGCTGCACACGGGCGAGAAACCGTACCAGTGTGAGATTTGCGGGCGCAGCTTCCGCCGCGTATTCAGCTACAAGGAGCACATGGAGATGCACAACCCGGAGGCGAGCTACAACTGTCCGACGTGCAACAAAAGCTTCAAGCGGCCCCGGTACCTGCAGGCGCACGTGCTGACCCACACCGCGGCGCGCAAGTTTTCGTGCGAAATCTGTGGCAGCTGCTACAAGACGAACGGGGAGCTGAAGAAGCACACCAAGAACAAGCACGGGCTGGACATtgtggaggaggaggtgcgcgAGATAGTCATCGATGCGGAGGATACGGATATATCGTCGTTCGTTGTGGAGTACGTTTGA
Protein Sequence
MSAECSDASTDPRLLQYRDLFCRICLQYSKGALIPIGAEIKKTTLLDMFIQLTTFELDHNDAFPRFMCEQCVSKLTLAYSIREEFISQTDLLLKLVVQKQIIKYYEQFPLEPKVQAPPKVIQPSVHAPFRELKPTRVAKPTGGVPVVKPQQMLIQESIKDETVEELDVDEEVIQEEILNDTTTNTVPLDESSLAVDFKDDWDSSSTATSLDEDDWSYTLNPITPQKLEELNAARPVRMKNPSGSRKRPKPAEEKQDKKERKNQYSTTTCYICDTHHESIAQRDDHFRNHIHMLPYECTECLADPPPEDADSPRKDQPAAEHPTHIVLRSVIQLNSHMMMHGFPHKCEHCYRRFTTVYLLNHHLWNYHQHSKEGLTCEWCGKRYYSRRPFQEHVRRHKHSVTERFKCTTCGRAFGSNALLRRHEMVHTGERSHKCTYCPRLFSRRCNLLDHLRLHTGERCHKCSECPQSFNTKSSLEKHQRNYHSDLAVVPPRGDRNIYTLQSDGSRLYRCKHEGCTFTSTSSTTMTQHRLRHNKPCVCEECGQRFVSPKYVRKHMNLMHSGKPRKPQGKGGAGGGTKKVKEEISDASSATILPADNTTELISADESLLETKLEEEEEIQPDDEAWVKMKDGIIRTEWNAGDLNVVREYVVEFVEDSKEIEITLHTFDSCTVSAMFVYKTMEQLQREDAATTSCPMESYSTAPQTAVLQRFCRLCMREFPFLLPFNATLKEIALADMLERLLGSFKLKQAPNLPNGVCSHCVAKLDYAYHVQKELVRNEQRLRHFQQEGNLLQKLFEYQANITVTKEDGGGDRMVAGYGSGLLPETIQLDPKQDVPDMADAEQRAAAAYKTLIPPGGWVVMECDCPEKSMAASTRRAPRSMKPARPQQRTLRNRHVLRQAIDAENPTALNATAIDPCKCYICNTVLESEEDCRAHLAVHVDMLPHVCPECSTPNASEEDDDAPSTPITSLAMLQRHYRMHSYPLKCPHCPQRFRKHTSVYTHVRYRHEMFDNPEGFTCDVCGVTMQYRPSFMYHMRIHYHEQMGTFRCQYCDRVFGTRARLERHERAHTGERPFACHLCPKTFVHAGQLATHIARHNNERGHRCSQCGKAFYSKAMLRQHLETHETHETRKASNAAKVRQRPCAYAGCTHVARTYQAYYMHRLRHEMAHRCEECGRRFARACELRRHRRIYHSSEHPFRCEPCGKTFLSSQSYREHMDSHANVRRFECEVCDKKFVRRRNLVNHRMSHTNQRPYRCEYCDSTTFKYKSDLNRHRKDKHGQAEHGEQTSALAQEDEDGADGEKIVLMNADDPIMDVILEESAPQGILINENIELDGTYGEEIETVEESIVVEQPIVSIGIDEVTKEEYIIEYINHVTSDAFCRICLLKRPHLKSLMERVDGVMIPEMLYKVCGRQIEVQEGYPRSICQRCLCQLDCAFKFLNEFHQQDERLRSFYWSGSVVKRLQEYQKEGSETVEKRFAELVTRNAKMLSPPTKHMCHRETNTSQRPKLVDASTLTDKEAVADLALVKTEDGSVVSDDLVVEDEEGVYLEYADDFDASIKDEQLVSMKIDVLQSGDEAESDAEPKERRKRAPHTATKSTPSSRWSTRTSQPLPTKQQEDSDTDDPATEEDFKELFEESEPDTVLEIDEDEEDDDFDEEDEEEDEEEDDETEEGKHMVEEQTPPVQLDPLRCYICDRNEESKAMLEQHLDMHSLMLPYECRICQVEGGPARTLKTISSLQNHFRSHHYPFGCGTCGKRFLRKAHLMTHMDSHNEEHLECGECGRQFTHRKTWQNHLKRHVALRTGAFKCGTCDRAFGNRARLDRHVRSHTGERPFGCKYCDKRFYDRHQQQRHTERHFRDQECSCEICGETFPGAKKRDQHKVEQHLHGPELEAFLARKSRQRSYKKPAVLKDKKCPFAGCDYVANTYGAMYVHKRSKHQPVHKCELCNKSYAFLNQLRVHMALHTGEKPYQCEICGRSFRRVFSYKEHMEMHNPEASYNCPTCNKSFKRPRYLQAHVLTHTAARKFSCEICGSCYKTNGELKKHTKNKHGLDIVEEEVREIVIDAEDTDISSFVVEYV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-