Aaqu005087.1
Basic Information
- Insect
- Anopheles aquasalis
- Gene Symbol
- Rreb1
- Assembly
- GCA_002846955.1
- Location
- NJHH01004288.1:16954-28446[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0034 0.21 11.6 1.1 2 23 111 132 111 133 0.96 2 13 0.00012 0.0073 16.2 0.1 1 23 162 184 162 184 0.97 3 13 0.0017 0.11 12.6 7.8 1 23 190 212 190 212 0.98 4 13 0.11 6.8 6.9 4.9 2 20 425 443 425 444 0.95 5 13 7.4 4.7e+02 1.1 0.4 1 19 490 508 490 510 0.86 6 13 0.01 0.64 10.1 0.1 1 23 705 727 705 727 0.97 7 13 5.1e-06 0.00032 20.5 0.3 1 23 736 758 736 758 0.99 8 13 0.0016 0.1 12.6 2.3 1 23 764 787 764 787 0.97 9 13 0.00093 0.058 13.4 2.1 1 23 1343 1366 1343 1366 0.95 10 13 8.4e-05 0.0053 16.7 0.3 2 23 1862 1883 1861 1883 0.97 11 13 0.43 27 5.0 5.4 1 23 1889 1912 1889 1912 0.96 12 13 0.019 1.2 9.3 0.4 3 23 2257 2277 2255 2277 0.93 13 13 0.0038 0.24 11.4 5.6 1 23 2283 2305 2283 2305 0.99
Sequence Information
- Coding Sequence
- ATGGATGCTGGCAGTCGGTTACCAGTAGCAGCGGAGGGGACCGGTACGGCGGACACAATCACCGCCACGATcaaggtggaggtggtggatgcggcggaacagaagcagcagaagcaacagccgagcgatcagcaccaccacagtgTTGGCcaacggCGCCAGGCTCAGCTTGTTGGCCAACAGGCGGACACCATTTCGGCCTTCGATAAAGGTGCTGATGGgtacgagcaacagcagcaatcgcatGCCGCATcattgccgccaccgccgccacttGCCGATGAAGCTgatcagcaacaccaccaccaccaccacagccaatGGCGTCGCAAGTGTCCGATTTGCGACGAGCTGCTGGCAAGCAACCACGATCTGACCGAGCACGTCCGTTCGCATCATgccgtggagcagcagcagcagcaggcctcGTCCGGGCGGGAATCGGCGCAGAGTGTCGGCGCtgccagcggcaccaccagtACCTTTGTCTGCAAAATCTGCTCGAAGGTACTGTCGTCGGCTTCGTCGCTCGATCGCCACGTCCTGGTGCACACCGGCGAACGACCGTTCCACTGTAAGCACTGTGCGCTCACCTTCACCACGAACGGGAACATGCATCGGCATATGCGCCTGCACAAGAACTCGCCCGGGCGCGACAGTATcgagcagcacagcagcagcggcgacggtggtgccACCGGTAGCGAAGGTGGCGTACTGCCACCGGCGGCTTcttccgatggtggtggtggtacctcctcctcctcctccgccaccgctgGCGGCAAGGTTCGCCGGCGGAAGCGTGCCgagccgcagcaacaacagcaggaccAGTTGATCGTAgcggccaccgcagcagcagcagcagcagcatcgcaccgGTCCAGATTCGAAGCGGGGGAGCAGGAAGAGCAGGAAGACCGTAAGCAGCTAAACCAGCAGTTAATGGAGGAGATgaagccgcagcagcagcagcaattggaGAGCGGtgatgacgaggaagaggaggaaccacatcctggtggtgatggtggtgggcgtcgtcgccgtcgtcgccgtcgacgccGTACCGCCATTATTGCCCACTGCGTGCgcacgatcaacaacaacctgcTGGAGGGTTCGGTGGTTGAGactggtggcgacggtggtggtgacggtggcggtggtggccagcgctTCTGTTgtccggtgtgcgtgcgcaaCGACTTCGGCagcatgctgatgctggagaACCACCTGGACCGGGAGCATCCGTCCATACCGGCCAAGTGTCGCCACTGTGAGACCGTGTTCCGCAGCCACAAAGCGCTGAATGCGCACCggtgctgcaacaacaactaccAGAACATCACGCCCGGCTTCAAGGATCTCACCTTCGTCGACTTCTCGAGCGAGAAGTTTCCGCTGATTGCGAAAAACTTGTGCGAACAGAGCATCCGGACGCCGGTGACGAACCAGAAGTACGAGTGCGGCCGCTGCTACCGTGCCTTCCCGTGCTCGCAGACGCTGACCATGCACGCCGCCGAgtgtggcgtcggtggcggtaaGAAGCGCAAGCGCGCCCCGAGTGACTCCGATGCGTCCGATGTGCCGTCCGAGAACCGCTCGATCGGTGGACTGTCGGAAGCACCGACCACACCGTCCTCGCTAGAGAAGTCGTTCTCTTCCCCGATGGTCAAACTCGAACCACTCGATTCACCGACCGGCGGTGGGGACGGCGGTAGTGCGTCCACCATGCACACGTTGTACTATCACCACTCCAGCCCAGTGGCCGGTGGTACGGCTCTGttccaacaccatcaccaccagcagcagcatcttcaggATGGTGGCAAGGATCTGGCCGATATCCAGAGCATTATCAACGTGGCATCGTCGGGCGGGCTGTttgggcggcagcagctggacGGTGTGACCACCGACAGCAGCCACACCACGCCCCTGTCCGGGCTGGGCGGCGGACTGGGCGATGGGCTGATGGGCAAGGACTGTGgcggtagcaccagcagcgtgtaCGCCCATTCGACCGGTTCCCGCGGTGATGACGGGGAGGAGGCCCAGGACGCGTTTACGGCCGAGTTCCGGCGCATGAAGCTACGGGGCCAGTTCCCGTGCCGGATCTGTACCGCGGTCTTCCCGAACCTGCGGGCACTCAAGGGCCACAACCGGTCGCACGTGACGGCGGCCGGACCGGGACCGTACCAGTGCAACATGTGCCCGTACGTCATCAACGATAAGGCCACCCTGATCCGCCACATGCGCACCCATAACGGGGACCGGCCGTACGAGTGTGCCCTGTGTAACTACGCGTTCACGACGAAAGCGAACTGCGAGCGGCACCTGCGGAACCGGCACGGGCGGACGACGCGGGACGACGTGAAGCGGGCCATCATCTATCACCCATCGGAGGACTCGTCGTGTGAGGATCCGCTGAAGAAGCTGCACCTGTTCAATACACCGCCCGCCGACTATGAGCCGACCGGGGcgaccaccggccagcgccatcatcaccaccaccaccaccaccaccaccaccatgccgCCCTGCTCGGTGGctacgatgagcagcagcagctgaaggaccacttacaccaccagcagcagcaacagcagcgcagcagcacaccactgTCATCGACTTCGTCGCACTTGAAGGATAtgctggtgccaccggtggcactaCCGCCGCTGGGTTACgtttccggcaccaccaccaccaacccactGCTCGACACTAGCCTACTGCTGCAGACACCtcctggcggtggcggtggcggtggtggtggttgtgacGGTGGTAGTGTGGCTTTTGGAGCGGCAGCCATCGGGGCGAAGATTCAGGTGAAGAGCCTGGAGAAACTGAACCAGCTGACACCaccacaggaggaggaggaggaggaggaggaactgcAGGAGAGCTACGGACCGCTCAACGATACGAGTGGCGAACTAacaccgataccaccaccaccacaccgtccaAAGCAGCAACCtacggtggtagcagcagcagcagcagcagcagcaaccgtaccGACCCAGCGTCCCATCGATCTGAGCATGGACGCGCTCGATTTGAGCAAGAAACCGTCGAGCTCGAGCAGGAAGGtggctgccaccaccaccgacgaagatgatgacaacgaggacgatgaggtggacgacgaggagcacgatgaacagcagcagcactacgaGAAGGGATCGGTGGTTGAAGCTCGACTGAACGGGGATAGGAAGTGTAATGGGGAAGCCGCTCCCACTGCCACTGGTTCTGATTCTGCTGAACGGCGGCGCCGtccccaccaccgccatggtGCAGATGTGGAGGAGCTGTATCAGCTCTGCACCCAGCTCAACTCGCTACAGTTACCCTCGTTCCCGTCGCCGCTACAcacggccgccgccgccgccgccgccccatTCCTGCAGAACTCGATGCtggcggccgccgctgccggtggcccACTGGGCGATCTGTTCGGCAAAGACTTTGGCCTTGGTACGTTGCCAAATTtagcggctgctgcggctgcagcagcagcggcagcggccgcttCTACCGGTCGCAACACCGGTGGGCACTCctcgcgtggtggtggtggcaatacCAACCCATACGCCTCACTACTGTCCATGAGTAACCCGTTCCACTCTGGCGCCGCTGAAGCATCGGTGAAAGGGACCGGAGCATCATCGGCCAACCTGATTGCCGCTCCAtcatcgaccagcagcagctcctcaGCGTCGTCACTACTCCGCCAGTCATCACCGATTTCATCGTTGGCATCGCCCGGCACCAAGACaaccacacatcatcatcatcatcaccattcccaggcggcggctgcagcggccgcagcagcagcagcagctgcggcagcCGCTGGCTACGGtgtcccaccaccaccaccaccaccacccggtgggACCACTAGTGGTGGTCCGGTCAAAATGGTCATCAAGAACGGGGTGCTCATGCCGAAGCAGAAACAGCGACGGTATCGCACCGAGCGCCCGTTTGCCTGCGAGCACTGTTCCGCTCGGTTCACGCTCCGCTCGAATATGGAGCGCcacatcaagcagcagcatccccagTTCTGGTCACAGCGccagcgtggtggtggccatcaccTGATGCGCCGTGGCAGTGGGGGACCGTCGGGTGCGGCGGCAGGAgcagctgcggcggccgctgcagcagcagcagcagccgccactgCTGCAGCCGGTGGCTCACTGGCCGCCGCTCTGCAAGGTGGCGTGTTCGGTGgaccaggaacaggaacaggaggacTATctagtggcagcagcggcggtggtCAGGCTATCTCGGAGCAGGTCAAGTATGCGATCTTGGCGCAGCAATCGGGCAAGGGAGGACCTGGAGTTGGTGGGCTCGGTTTGCACCCGCTACTACAGAACATGATcacgcatcagcagcagggtggtggtagtcAAGGTGGTGCCGCATCCGACCATTGGAATGCCTCGAATGGAGCTGGTGTcgtgcagcaggagcagcagcatctgtcGCAGGTGATCACACcgatacaccaccaccgttccaaTCTGACGCTCAGCGAGCGTCGTAGCTATCAGGACAAGACATCGGTTTTGCAcaatcacaaccaccaccacgcccatcaccgccagcatcggcatcgtcgccgttgtctGCAGCCCGAGCTCGATGAGCTCGATGAGGAactgcatcaccagcaacagcagcagcagcagcagcaactggaacAGGAACGCCACGACGCCAATCGCCATGATAGCGCCGTTTCACCTTTTCCCTCCGACGGCACACTAGCGGAGCGGCCGAAGCACCACGCGGCCAACGAGCGGCGGGAGCAGGACGAAGAAGAGGCGGAGGACGACTCGACCCAGCAGCTCGTAatcgacgaggaagaggatgtggaggaggatgagcaagaggagagggaaaaagaggaaagagaaggtGCCGGGTCGAAATCTGACTCGGAGCGTCGTGACGGTGGAACAGAGGTGATCCCGCaagccaacaacagcaccagcggtggtgAGCATaatggcggcggcagtggcgtcGTTGCAGCCATCACGAACCGCATACTCAAACAGAAGCTGGAACAAGGTCTCAACCTGGGCTCGAGTGCTTcctccgagcagcagcagcagcagcagcaggttgctgCTCAAGCGGTGGCCAAAGATATCCTCGAGCAGgcaaagcaacaacaggagcagcagcagcagcagcagcagcagcagcagcagaaacaatcaccaccagcgcaatCCAGCGCTAGCGTTATCGATGAGGGCATCAGCAACAGTGACCTGGTGCCGGTTGCCAAACTGCTCGACAATGCGACACACAACAATGCGGCGCTGGAAAGTTACTTCAGCAGACCCGAAGTGGTGCCACTGGCACACGATCACAGCGACGAGGAGGGCCTGGTGGCGTCCGGGTCCGCGTCCGAGAGTAACAACTCCGGCACCGACGATCCGTACCCATCGGCGGTcgcgctgctgcaccagcagcagaagaaaaagtccGCGTACAGCCTGGCACCGAACCGGGTCAGCTGCCCGTACTGTCAGCGCATGTTCCCGTGGTCGAGCTCGCTGCGGCGTCACATCCTCACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCAGTGTACGCTACTGTTCACCACCAAGTCGAACTGCGACCGGCATCTGCTGCGCAAGCACGGTGACGTCGAGTCGGCCGTTTCGATACCGGTACCGATCGACGATCTGCTCGatccgaaaccggaaccgatcCCGGTAGCCGTGGCCGAGGCGATGAACAAACGGTCGTCCGgtggtaagcagcagcagccgtccaGCAAGGGTGGCACTGTCTCAGCTGCTGCGGGTACCGGCAGCGGGCCGGCGGCGGCAGGCTTACCGGGCCTGGCGCCCACCGAGCTAGAGCCCCtggacggtggcggcggtctGTCAGCAACAGTGGAACAGCAGggccaagaagaagaggacAATGAAGACGAGGATGATACgcctggtgatgatgctactgcGACGCACGTGGTGCGACGGAAGGAACTGCCGGATGGCGTGACGGAGAGGGTCGAGAAGCCGAACAGTGGGGGGAGAAGCAGCCCCCTATCAGCTGCTCTAGTAACCAATGGTAGCACCGCGAGTAGTGACGCTGAATCGTCAGGTGGTAGTCCCGATGGGCACAACCTCCGCCAGGATGCTAGCGGGCGAGTCACCAAGGCACCTGCGCCGGTTCTGAATGATCTCGAGGCGAAGCAAGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNgaggaggaggaggaggaggaggagtacgGCGAAGACGAAGCAGCTGTTGGCGGTACCGCCGGCGATCGCAGCACCGGTCTGGCGGATCTACCGTTCAAGTGTCATCTGTGCGAAAGCTCGGCTGCGAACCGGGGCGCCTGTCTCGAGCACATGCGCCAGTGTCATCCGCAGGACTTTGAAGCGCTACGGTCGAAGGTGGCACTAGAcgcggctggtggtggtggtggtggtggtgctagtggcgGTGACAGTGACGGCCAGACAGTGACCACCAACTCGccggatgaggaggatgagagCGGCAACAATGATACGGCTACGTGCAGTCCCAGGCTccatagcaacaacaacaacaacaacaacaacaacaacaacaacaacaacggtggcaaGTATCCCGACTATGCCAACAGGAAGGTTATCTGCGCCTTCTGTATGCGTCGCTTCTGGTCGGCGGAAGACCTGAGACGCCATATGCGGACACACTCCGGTGAGCGACCGTTCCAGTGTGACGTTTGCAGTCGCCGCTTCACCCTCAAACACAGCATGCTGCGCCACCGGAAGAAACATGCCATCAacggctgcggcggcggcggcggcgctcCTCACCATGACCGGCATTCGTCTCGGCGAGTTTCCACCGGCCCCAACCCCTCCAATGGCTACCGCTACCACGaccgtgacgacgatgatgaccaCAGTGGTCGATCCGACCTCAGCGACGAAGACTACTCGTCTTCCTCCGCCTCGGCCTCACCCAGTCCGTCCACTCCGGCGCTCCCAACGGCAGGCCGGCTCGTCAGGAAgcaaaggaagcagcagcagcaccaccagctgcactACAACAACTCGGAACTGATTGGCAATCTGCTCGGCATCAGCGACCAGGGCATCCTTAGCCGGGTGCTGCTCTCGTCCGCATCCGAAGCGGCCAAGCTGTTGGGTGTACacaagtag
- Protein Sequence
- MDAGSRLPVAAEGTGTADTITATIKVEVVDAAEQKQQKQQPSDQHHHSVGQRRQAQLVGQQADTISAFDKGADGYEQQQQSHAASLPPPPPLADEADQQHHHHHHSQWRRKCPICDELLASNHDLTEHVRSHHAVEQQQQQASSGRESAQSVGAASGTTSTFVCKICSKVLSSASSLDRHVLVHTGERPFHCKHCALTFTTNGNMHRHMRLHKNSPGRDSIEQHSSSGDGGATGSEGGVLPPAASSDGGGGTSSSSSATAGGKVRRRKRAEPQQQQQDQLIVAATAAAAAAASHRSRFEAGEQEEQEDRKQLNQQLMEEMKPQQQQQLESGDDEEEEEPHPGGDGGGRRRRRRRRRRTAIIAHCVRTINNNLLEGSVVETGGDGGGDGGGGGQRFCCPVCVRNDFGSMLMLENHLDREHPSIPAKCRHCETVFRSHKALNAHRCCNNNYQNITPGFKDLTFVDFSSEKFPLIAKNLCEQSIRTPVTNQKYECGRCYRAFPCSQTLTMHAAECGVGGGKKRKRAPSDSDASDVPSENRSIGGLSEAPTTPSSLEKSFSSPMVKLEPLDSPTGGGDGGSASTMHTLYYHHSSPVAGGTALFQHHHHQQQHLQDGGKDLADIQSIINVASSGGLFGRQQLDGVTTDSSHTTPLSGLGGGLGDGLMGKDCGGSTSSVYAHSTGSRGDDGEEAQDAFTAEFRRMKLRGQFPCRICTAVFPNLRALKGHNRSHVTAAGPGPYQCNMCPYVINDKATLIRHMRTHNGDRPYECALCNYAFTTKANCERHLRNRHGRTTRDDVKRAIIYHPSEDSSCEDPLKKLHLFNTPPADYEPTGATTGQRHHHHHHHHHHHHAALLGGYDEQQQLKDHLHHQQQQQQRSSTPLSSTSSHLKDMLVPPVALPPLGYVSGTTTTNPLLDTSLLLQTPPGGGGGGGGGCDGGSVAFGAAAIGAKIQVKSLEKLNQLTPPQEEEEEEEELQESYGPLNDTSGELTPIPPPPHRPKQQPTVVAAAAAAAATVPTQRPIDLSMDALDLSKKPSSSSRKVAATTTDEDDDNEDDEVDDEEHDEQQQHYEKGSVVEARLNGDRKCNGEAAPTATGSDSAERRRRPHHRHGADVEELYQLCTQLNSLQLPSFPSPLHTAAAAAAAPFLQNSMLAAAAAGGPLGDLFGKDFGLGTLPNLAAAAAAAAAAAAASTGRNTGGHSSRGGGGNTNPYASLLSMSNPFHSGAAEASVKGTGASSANLIAAPSSTSSSSSASSLLRQSSPISSLASPGTKTTTHHHHHHHSQAAAAAAAAAAAAAAAAGYGVPPPPPPPPGGTTSGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQFWSQRQRGGGHHLMRRGSGGPSGAAAGAAAAAAAAAAAAATAAAGGSLAAALQGGVFGGPGTGTGGLSSGSSGGGQAISEQVKYAILAQQSGKGGPGVGGLGLHPLLQNMITHQQQGGGSQGGAASDHWNASNGAGVVQQEQQHLSQVITPIHHHRSNLTLSERRSYQDKTSVLHNHNHHHAHHRQHRHRRRCLQPELDELDEELHHQQQQQQQQQLEQERHDANRHDSAVSPFPSDGTLAERPKHHAANERREQDEEEAEDDSTQQLVIDEEEDVEEDEQEEREKEEREGAGSKSDSERRDGGTEVIPQANNSTSGGEHNGGGSGVVAAITNRILKQKLEQGLNLGSSASSEQQQQQQQVAAQAVAKDILEQAKQQQEQQQQQQQQQQQKQSPPAQSSASVIDEGISNSDLVPVAKLLDNATHNNAALESYFSRPEVVPLAHDHSDEEGLVASGSASESNNSGTDDPYPSAVALLHQQQKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSQCTLLFTTKSNCDRHLLRKHGDVESAVSIPVPIDDLLDPKPEPIPVAVAEAMNKRSSGGKQQQPSSKGGTVSAAAGTGSGPAAAGLPGLAPTELEPLDGGGGLSATVEQQGQEEEDNEDEDDTPGDDATATHVVRRKELPDGVTERVEKPNSGGRSSPLSAALVTNGSTASSDAESSGGSPDGHNLRQDASGRVTKAPAPVLNDLEAKQEXXXXXXXXXXXXXEEEEEEEEYGEDEAAVGGTAGDRSTGLADLPFKCHLCESSAANRGACLEHMRQCHPQDFEALRSKVALDAAGGGGGGGASGGDSDGQTVTTNSPDEEDESGNNDTATCSPRLHSNNNNNNNNNNNNNNGGKYPDYANRKVICAFCMRRFWSAEDLRRHMRTHSGERPFQCDVCSRRFTLKHSMLRHRKKHAINGCGGGGGAPHHDRHSSRRVSTGPNPSNGYRYHDRDDDDDHSGRSDLSDEDYSSSSASASPSPSTPALPTAGRLVRKQRKQQQHHQLHYNNSELIGNLLGISDQGILSRVLLSSASEAAKLLGVHK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -