Aaqu009251.1
Basic Information
- Insect
- Anopheles aquasalis
- Gene Symbol
- -
- Assembly
- GCA_002846955.1
- Location
- NJHH01000868.1:24344-29675[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0037 0.23 11.5 3.8 1 23 352 374 352 374 0.95 2 15 4.8 3e+02 1.7 0.1 3 8 378 383 377 400 0.87 3 15 5.2e-05 0.0033 17.3 2.4 1 23 405 427 405 427 0.95 4 15 7.6e-05 0.0048 16.8 1.8 1 23 445 469 445 469 0.92 5 15 0.003 0.19 11.8 0.5 2 23 475 497 474 497 0.94 6 15 0.0081 0.51 10.4 0.1 1 23 523 546 523 546 0.97 7 15 0.02 1.3 9.2 4.8 1 20 553 572 553 575 0.94 8 15 1.1e-05 0.00067 19.5 4.1 1 23 581 606 581 607 0.97 9 15 0.052 3.2 7.9 0.8 1 23 813 836 813 836 0.95 10 15 0.016 1 9.5 0.3 2 23 854 877 853 877 0.90 11 15 0.17 11 6.2 0.1 3 23 884 905 882 905 0.95 12 15 0.00049 0.031 14.3 0.2 1 23 911 933 911 933 0.97 13 15 0.067 4.2 7.5 0.2 3 23 943 964 941 964 0.95 14 15 0.0082 0.52 10.4 3.7 1 20 970 989 970 992 0.95 15 15 3.8e-05 0.0024 17.7 0.1 1 23 998 1023 998 1023 0.97
Sequence Information
- Coding Sequence
- ATGGAAGTGAAAATGCAGCACAGATCTCGAGTTCACGTGTTCCAGATACAGGTCAAAGCTTTGATCAAAGCGCTCAAATGTCTACAGTCCGACGACAAATATCAGGCGCTCCTGTTTCTCATCTCGGCGATCAAGCTGTACGTGAAGATACTATATACCGACTGCCAGGAGCGCATCTATAAACCAGCAATACTCAGAGAGCTGCACAACATCGAGAATGTGATTCTGGTGAACCTGCTCAAGACGCGCGGCAGCGCCGCCGCGTCCGGGTCGTCCTCCGTAGGCACGGGTCACAGTATGCTCTCGCCGTCGTACGGCGGCACGGAAGGCAAAGTTTCCTGTCtcgacatcagcagcaccagcgtgcgAAGTGCGGATCTATCGATCGGGGccgatgggctgctgctgatgatgcgacaacagcagcagaactcgAGCAGTGCTCCGCTGGCGCCGTGGGATTTGCGTGGCAAACTGCTGCGGGGCAACCTATTTGATGGGTTGCTAGCGGCAACGGCGAGAACGAGTAATTCGTCCGTAACAGTGCAACGCCCTCCTCGAAAGTGGTTGGGTAATTGGCGAATGAACCGATCGCTGGTGCGCCTGATAGCGAACCACGATTTCAAGCTGCTGTTCAACATGTTCGAACAGAGCATCTTCCCGACGTGGAAAATCTACAAAAACGAACAGATCTTCGTCCGGAAGCGACCCGCCCTGACGACGGTAACCGTGCGTACCTCGCTACCTGCCCTATGCTACGGCGAAGGACTTTCGCATTCGCCTCCTGCGACCTACATCAAGAAGGAGGACTACGATTTCGATCCACCGTACTCGCTCACGGACGATCACTGCTTCGAGGACGTcaaggacgaggaggaagatgacATGATTCTAAGAATGAAAGATGAAGATTCCATCGATAATTCGAACGAAATCTTCTCCGAGGAAGAATCGTCAACCAACAACACCTCGCTCATGCTTTCCTCCGACACCAACACGCTCGATACGAACGACTCGAGTATGGTTTCACACGAGCGCAACAAGGATCAGGTTTATCAGTGCTTACTGTGTGATAAAAGTTATAGGAAAAGGAAATCTCTCGTCGTCCACTTTAGCCATCATCCCGGATTTTGTCCAGATTGTGGCAAACAGCGTGGCGTCACGTCGGAGGAAATTGTTGAACACAATCGGATATACCACAAAAACCGGCCACACATATGCGAGCACTGCGGCGAAACGTTCACCCGCAACCAACAGTATCAGATACATGTGCAGGGCCACTTCATCAGCAAGGACCAGGTTGCGGTGCAAAATTGTAAAAaaacacacaagTACAGCTGCAAGACATGCAGCATCGTTTTCAACAATCAAAAGTATCTCGAGAAGCACATCCAAAAGACCAACCACCAGGCGGAGGGTTTGGTGTGCGACATTTGTGGTGCAATATTCTGTAACAGTATCAAGCTCAGCCAGCACGTCACCCGAACGCACAACGATGTGTTTACTCAAAAGACGACGCTGGAGCGAAGCTTACTACTTCAGGGCGCGAGTGTAACGGAGAAAAACTATCCCTGCGATCAATGTGGTGCTTCATTTCTATCTCAGCTCTCGCTACGAGAGCACGTAAAAATTTCTCATCCCGTTCCGGAAAATAAGTTTGAGTGCAACATTTGCCACAAACTGTTCGCTGCCAAGCGGTCCCTAAAACGCCATAAACTTTGCCATTCGGACGAGCGTGCTTTCCGCTGCACCGTAGAGAACTGCAAGGAATCGTACAAAAACCAATCGCATCTGGCGCGTCACATGAAAACGGCGCATCACATTGATCCACCCTCGAAGCGACTGCAGAAGGCGAAGGCTGCCGCAGCGGCGTTggcctcttcctcgtcctctttAACCGGCACGGATCCTACAGCAAGTGGCGAGCTGTTTGCTGGCCACACTGCCGACGCTCAGATGGGAGGCTCGTGTGATTCGCTCAAGGTGACCGGAGCACTGAAGAAATCACTTGGTAGCAGCGAGAAGTCACTTGGCGACAGTAGCACCAACTTTAGTGACAATATGTCCGCCTTTAACTACGAGTTTTCCGATACAACTGGAGGCACATCGACACCGGCTATGCCGGTGCACGAGCAAAACTTACTTCCCACAACCGGTAGTGCACTGATGCCGAacaacggtggtgctggtggtccctcatcgatcatcggtAACAGGACAGCGGCTCTCACGTGTGCGGTAGGCCCAGGGCAAGGTCCGACAGGTGCTTTCAACGATCCGACGATAGGCTTCGGGAACAATAATGGTGCCAGCAAGCAGCCACATCTACCACATCAACAGCAGTCGCTACCACACCCACAGCAACcggtgcagcaacaacacatgGGATGGCAGAATCTCGACGGTGCTAGGCGATTTAATCTCCCGGAAAACAGCTTTATCTGCGAGCATTGCGATGAAACCAACTTCATCAACGCCCAACAGTTCCAGTTACACATTCAGGATCACTTTGCTGGCAAGGAGGGCAAAGAGCATCCCAGCAAAAAACTACAACGATTGAATTGTAAAACGTGCAGCCTGGTGTTTGCCACTGGAGCCCAGCTCGATCGGCACATCCAGAAGACGAACCATCACACCGAGTGCATAGCGTGTGAGATTTGTAGTGCAATATTCAACTCTAATTTAAAGGTTTACCAGCACATGCTGAAAGCACATAAGAACGataTTTGGTACGCTTGTGAACAGTGCTCAAAAGTGTTTATCGTGAAGGAGGAGTACGACAAGCATCAGCTAGTGCACCAAACGATCACGGACCGGTCCATCATCTGTGAGCACTGTGCATCATCCTTCCTCACGCAAGAAGCCCTGAAGGAACATATCAAAATAGCGCACTCGATGGATAAAAAATACAAGTGCACCATCTGCAACAAGCTGTTCGCCGCACGGCGTTCGCTGAAGCGCCACAAACTTtgccacgaagaagaagcagcctTCCGCTGTTCCATCGATGGTTGCAACGAAGCGTTCCGTACGGCCGGTAATTTAGCGAAGCACAAAAAGATGGCCCATCCAGCTGGAGCACcgtcttcggtggtggcagctaACGCCGCAGCTGCGGCTATTGCCAACGCCGCTGTTGATCCACTGAACGACAAAATGACCACCAGTGGGACAGGTCTGGTTGGTCAACAGGGAAGTAAACACCCAAATGCGATGGTTGTATCGAATGCAAGCGGAGGCGTAGCGATGGGCCCAATGAAGCTACCGGACAAGTCGCATTCGCAAGACATGATGGGCAGGAGTCTAAGCAGTCAGGGATCCGGCATCATGTCACCGGCAGGTCCGGGCGGAAATGTTGGCATGATGAACTTGGCATCCGGCGGTATgatgagtggtggtggtggtgctggtggtccagGACACAGTAAGAGTGACCGATCAGCCGCTGGCGGATTGATGGTACCACCTTCGAGAACCCCCAGTGCCGGGAGTAGTGTCGGAGGCAACCAAACCATGCCTTACAGCCCCTACGATGGGACCAATGCCGCCATGCATTACAACATGGGACTGTACCGAATGCTTCCAATCTGCCTTACGCCTATGGTCAGCAGGTACAGAACCAGTTCGATTGGCAAACCATGGAACaactcggtggtggccaaatcGGTACCGCTGAATCGGGTGTAA
- Protein Sequence
- MEVKMQHRSRVHVFQIQVKALIKALKCLQSDDKYQALLFLISAIKLYVKILYTDCQERIYKPAILRELHNIENVILVNLLKTRGSAAASGSSSVGTGHSMLSPSYGGTEGKVSCLDISSTSVRSADLSIGADGLLLMMRQQQQNSSSAPLAPWDLRGKLLRGNLFDGLLAATARTSNSSVTVQRPPRKWLGNWRMNRSLVRLIANHDFKLLFNMFEQSIFPTWKIYKNEQIFVRKRPALTTVTVRTSLPALCYGEGLSHSPPATYIKKEDYDFDPPYSLTDDHCFEDVKDEEEDDMILRMKDEDSIDNSNEIFSEEESSTNNTSLMLSSDTNTLDTNDSSMVSHERNKDQVYQCLLCDKSYRKRKSLVVHFSHHPGFCPDCGKQRGVTSEEIVEHNRIYHKNRPHICEHCGETFTRNQQYQIHVQGHFISKDQVAVQNCKKTHKYSCKTCSIVFNNQKYLEKHIQKTNHQAEGLVCDICGAIFCNSIKLSQHVTRTHNDVFTQKTTLERSLLLQGASVTEKNYPCDQCGASFLSQLSLREHVKISHPVPENKFECNICHKLFAAKRSLKRHKLCHSDERAFRCTVENCKESYKNQSHLARHMKTAHHIDPPSKRLQKAKAAAAALASSSSSLTGTDPTASGELFAGHTADAQMGGSCDSLKVTGALKKSLGSSEKSLGDSSTNFSDNMSAFNYEFSDTTGGTSTPAMPVHEQNLLPTTGSALMPNNGGAGGPSSIIGNRTAALTCAVGPGQGPTGAFNDPTIGFGNNNGASKQPHLPHQQQSLPHPQQPVQQQHMGWQNLDGARRFNLPENSFICEHCDETNFINAQQFQLHIQDHFAGKEGKEHPSKKLQRLNCKTCSLVFATGAQLDRHIQKTNHHTECIACEICSAIFNSNLKVYQHMLKAHKNDIWYACEQCSKVFIVKEEYDKHQLVHQTITDRSIICEHCASSFLTQEALKEHIKIAHSMDKKYKCTICNKLFAARRSLKRHKLCHEEEAAFRCSIDGCNEAFRTAGNLAKHKKMAHPAGAPSSVVAANAAAAAIANAAVDPLNDKMTTSGTGLVGQQGSKHPNAMVVSNASGGVAMGPMKLPDKSHSQDMMGRSLSSQGSGIMSPAGPGGNVGMMNLASGGMMSGGGGAGGPGHSKSDRSAAGGLMVPPSRTPSAGSSVGGNQTMPYSPYDGTNAAMHYNMGLYRMLPICLTPMVSRYRTSSIGKPWNNSVVAKSVPLNRV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -