Basic Information

Gene Symbol
-
Assembly
GCA_002846955.1
Location
NJHH01000658.1:4631-7812[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0033 0.21 11.6 0.3 1 23 40 62 40 62 0.98
2 16 0.25 16 5.7 0.2 1 23 68 91 68 91 0.88
3 16 0.0088 0.55 10.3 2.0 1 23 94 117 94 117 0.98
4 16 0.0084 0.53 10.4 1.0 2 21 130 149 129 150 0.92
5 16 0.0016 0.1 12.6 0.3 1 23 158 180 158 180 0.94
6 16 5.3e-05 0.0033 17.3 0.8 3 23 188 208 186 208 0.95
7 16 3.2e-05 0.002 18.0 2.9 1 23 214 236 214 236 0.94
8 16 0.08 5 7.3 2.9 1 21 242 262 242 263 0.95
9 16 2 1.2e+02 2.9 0.6 1 23 618 641 618 641 0.90
10 16 6.7e-06 0.00042 20.1 2.2 1 23 665 687 665 687 0.98
11 16 0.00013 0.0084 16.0 0.5 2 23 723 745 722 745 0.95
12 16 0.00019 0.012 15.6 0.4 1 21 756 776 756 777 0.94
13 16 0.00047 0.03 14.3 1.4 1 23 785 807 785 807 0.96
14 16 5.3e-05 0.0033 17.3 2.6 1 23 813 835 813 835 0.98
15 16 1.6e-05 0.001 18.9 0.9 1 23 841 863 841 863 0.97
16 16 0.00034 0.021 14.8 5.2 1 23 869 891 869 892 0.96

Sequence Information

Coding Sequence
atgttttcctccAAAGAAAGCTCAGTTTTTAAGGAAAATTCCTCCAGCCAACCGCCCAGACAACCCAGGAAACGTGGACGTCCTCGCCAGGAAACGTTGAAGCATGACGCGACTCGGTTCACGTGCCGGATCTGCAATTATGAGCTGGTGGACACGATCGGGCTTGAGCGGCACCAACAGAAGCACGAACCACCGGGAGGATTTCTGTGTTCCGTGTGCAAGGCACCGTTCACGTCGCCCCAGGCAAGGAATGAACACAAAAGCCAGGCTCATCCCGTGTATCGGTGTCGGCTGTGCAAGGAATCCTTTCTCGATGAGGCACAGTTCCAGGCGCACCACAAAACGGTACATGTGGAACCAACCGAAGGAAGTAATGGCGATACTCTTTCTTGCCGCTCTTGTGGGACACATTTCCGGACGACATTCCAGTTGCGTGTCCACCTCGAGTCCAAGTGTGGAACGAAGAAGCACTTCCAGTGTGATATCTGCCAGCGGTACTATTCTTCGCAAGCATCCTTAGGTGTGCACCGGGGGCTACACCAGGCCAAGAAGAGCCATTTGTGTGATACCTGTGGAGCCAGCTTCTACAACCGTGGGCAGCTGAAGGTGCACGAACGGGTGCACACAGGCGACAAACCCTTCAAGTGTAATaAATGTGACAAAGCTTTCTCCCACCGTGAGAGTCTTGTGACGCACTCCTCCCTGCATAGTGGTATCAAACCGTACGTGTGCACGCATTGCAACGATCAATTTTCATGTAAAGGAAATCTCATCAAACATCTTCAACGGAGACCTCTAACTTGTGGGAGAAAGGAACAAGAAGTTAAAACCGTTTCCGATGACCCATCGAGTGCTGAGGGTGTGGTGGAAGAAGCGATACCCCTTCCGATCGTAAAGAGCGGCAAACGGGTACTCATTTCACGGACGAAATTAGACGACGAGAATGATGGTGATACGGAACACTTTGAGGTACAGGAAGTATCTGGATCTGAAAGTGAAGATACAGGACACCTTCTGAcaagtgaagaaaaaatggaaattattcCTGCGGGAGAGCACATAACGCTATTGGAAGTGGATCTCAATGCGCAAGGCCAGTCTGCAATAgatcaaaatgaaatggagGTTACTGTTCCTTGCtggaggatggaaaatgagGATGCTATTCCTACAATGAAGCACAGCGTCAATAAGCAGCATCTTCCTGACGCTGGCGTCGAGAACGAGATTGAGATGCTCGAACCATCCGGAATATCACTAACCGAAGAATGCGGCAAATCGTCTCCCGGTAGAGGCTCAGACGGTGAAGATTCGTACCTTTGTGTAATAGTCAACAATGGGCACGAAATAACTGGCGATGACGCAGAACAACACCATTGGTACACGATTGTCGCTTCAGAGACTGAAACGCGAGTTGAACCATGTCTTCCTGTGAAggaagataaaataaataatcagcAAACGACAACACTGAATGTATCTGCCACTAAGGAAGCCCTTGTCAGTCCTCCACCGACGGATTATGAACGGAAGGAATTGGAGAATGAATCTACCATCTCATCATCTGGCGACGAAAGCTTGTGGTTCGAAGAGAATATTTCGAATGCAAACGGTAGATCAGCTAGAAAGTCAAAGAAAAGTACAAACCCGAAACTAGTACGaaacatcaaaagcaaacTGAAAGATGAAATACCAACAAAAGAAACTTCAGCAGAGTCATCGAAGAAGCCGTCCAGAGCAGAACTTTCTCAAGATGAGATCGATGAAATGACGATTAGCCTAGAAGTGGAAGAGGTGGAGAAACAGTTGCGAACCTTGAAGGAAAACTACAAGATAGTAAGCGGTGCGGATTATCAGTGTAATCTGTGCCCAGTACAGCACACGTCGGAATATCTGATCGCCAGGCACCTCGATCGAATGCACGGTATTCAGCTGACCCCAGCTATTGAAATGCTGCATCTCATAAAAAAGCCCCCCTGGCCGGACATCCTCTATCGCTGCAAGTACTGCGGGCGGATGTACAGCAATCCGGCGCGATTGAAAGTGCATGTGCGGCATCACGGACCGCATGGTACGTTACTGCACAAGTGTACTTGCTGCAGCCGGTACTTCGAGACGGCAGAAGATAGCCGACAGCATGCGCTGGCTACGCACCGTGACCGATTGGTGTGTAACATTTGCCAGAAACAGTTTCAGGATCCAGATTGCTTGCAAGGCCACATTCGTTACGCGCATCGTGGTGTGAAGGAAAAACGTCGTTTAAACTTTGTATGCCTTCGGTGCGGTAAACGGTTTACTTCACGCTCCGTACTGACCGACCACGAACGATCCGATTGTGGTGATTCACCGATTTACAAGTGTGAGACATGCGGCAAGCATTATTCCAGTTACGGTGCATGGAAGGTTCACAAGGAGTTGCACAAAGATCAGCTACAGTTTATGTGTAGCTATTGCATGAAACGTTTTCGCACCAAGGGGCAGCTTAAGATTCACGAACGATCGCATACGGGTGAGAAACCGTTCCGCTGTGAGTACTGTCCGAAGGCGTTCCCATACCGGGAATCGCTCATGACGCATCACGCGATCCATACCGGAAACAAGCGGTTCAAGTGTGCGGACTGTAGCCAAGCGTTCACTTGTGCAAGCAATCTAAAGTCTCATCGTCGAACACACCATCCAAGCTAA
Protein Sequence
MFSSKESSVFKENSSSQPPRQPRKRGRPRQETLKHDATRFTCRICNYELVDTIGLERHQQKHEPPGGFLCSVCKAPFTSPQARNEHKSQAHPVYRCRLCKESFLDEAQFQAHHKTVHVEPTEGSNGDTLSCRSCGTHFRTTFQLRVHLESKCGTKKHFQCDICQRYYSSQASLGVHRGLHQAKKSHLCDTCGASFYNRGQLKVHERVHTGDKPFKCNKCDKAFSHRESLVTHSSLHSGIKPYVCTHCNDQFSCKGNLIKHLQRRPLTCGRKEQEVKTVSDDPSSAEGVVEEAIPLPIVKSGKRVLISRTKLDDENDGDTEHFEVQEVSGSESEDTGHLLTSEEKMEIIPAGEHITLLEVDLNAQGQSAIDQNEMEVTVPCWRMENEDAIPTMKHSVNKQHLPDAGVENEIEMLEPSGISLTEECGKSSPGRGSDGEDSYLCVIVNNGHEITGDDAEQHHWYTIVASETETRVEPCLPVKEDKINNQQTTTLNVSATKEALVSPPPTDYERKELENESTISSSGDESLWFEENISNANGRSARKSKKSTNPKLVRNIKSKLKDEIPTKETSAESSKKPSRAELSQDEIDEMTISLEVEEVEKQLRTLKENYKIVSGADYQCNLCPVQHTSEYLIARHLDRMHGIQLTPAIEMLHLIKKPPWPDILYRCKYCGRMYSNPARLKVHVRHHGPHGTLLHKCTCCSRYFETAEDSRQHALATHRDRLVCNICQKQFQDPDCLQGHIRYAHRGVKEKRRLNFVCLRCGKRFTSRSVLTDHERSDCGDSPIYKCETCGKHYSSYGAWKVHKELHKDQLQFMCSYCMKRFRTKGQLKIHERSHTGEKPFRCEYCPKAFPYRESLMTHHAIHTGNKRFKCADCSQAFTCASNLKSHRRTHHPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-