Basic Information

Gene Symbol
-
Assembly
GCA_002846955.1
Location
NJHH01002950.1:110169-117279[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 4.4e-05 0.0027 17.6 0.3 1 23 103 126 103 126 0.97
2 14 0.07 4.4 7.5 0.3 1 23 132 155 132 155 0.90
3 14 1.7e-07 1.1e-05 25.1 1.6 2 23 163 184 162 184 0.97
4 14 0.02 1.3 9.2 1.4 1 23 215 238 215 238 0.97
5 14 0.26 16 5.7 0.1 1 23 245 271 245 271 0.89
6 14 0.014 0.86 9.7 0.3 1 23 389 413 389 413 0.93
7 14 5.6e-05 0.0035 17.2 0.3 2 23 419 440 418 440 0.96
8 14 0.0023 0.14 12.2 3.6 1 19 480 498 480 501 0.95
9 14 0.24 15 5.8 4.4 2 23 517 538 516 538 0.97
10 14 2.7e-05 0.0017 18.2 1.6 2 23 547 568 546 568 0.97
11 14 2e-07 1.3e-05 24.9 0.4 1 23 574 597 574 597 0.97
12 14 1.1e-06 6.8e-05 22.6 1.4 3 23 605 626 603 626 0.97
13 14 5.6e-05 0.0035 17.2 1.4 1 23 632 655 632 655 0.91
14 14 0.00019 0.012 15.5 0.5 1 23 660 683 660 683 0.97

Sequence Information

Coding Sequence
ATGCAGCCAACTCTGGGTGCAGTTTTGTGTAAATGCTGCGGTGAGACGGCGAACAAATTGCAAAGCTTACACCGGAACGTGTCGGTGAACGGAAAGGAGCTGACGGTGCGCAAAATGTTTGAGATATTCCTCATTCCTTCGGAGATTTGCTTGCTTGAAGAGGATGTTGTGTGCGAACACTGTTTGGAACAGCTAAAGTTTAGCTACCAATTTTACGATAAATTTCTCGAGGCTCTCGCAGCAGCCACTAGCAAAGCATCTGCGCACAAACTCGATATACTCGAGCAGACTCTAGACGAAGTACCGTTCACTTGCAGCTTGTGTGATGCCTCTTTTGCCAACAATTTAGATTTGGAGAAGCATACGAAAATAATGCACTCCCCCGGGAAGCACTACTATTGTGCGGCGTGTGAAAAGCATTTCATTACCCAGCGAGGCATGGTGCAGCATACGGCAGCGATTCACCGTGATGCAAGCGAAACGGTTTCGTGCGACATTTGCCAAAGATCGTTCACTACGAGAAGTAACTACCAGAATCACATGCGATATCACAAGGATTATGTGTGCAATTTCTGTAACACCGGTTGGTTATCCGAGGCCAGCTTGCTCCAGCATGTCAGCGCAAATCACGCCGATCgcctgtttgtgtgtccgttcTGCGATCGCAAAGATCGATTGCGGAAAACGCTCAACCGCCACGTGCGATCCAATCATCAGCGACAAAGCTGTGGTTTCTTCTGTGGCTACTGCGGTGTCGGTAGTACGGGCTACGATAATTTAGAATCACTAAACGACCATCTAAAGCAGCTGCATGAAGATGAGAACGCACCAGCGAGCGCATACGAGCACCTGTTGAACGACAGCTTGTTCGTGAAGGAGCTGCCAGCACTAGAATCTGTAGACAAAGAACAGGAAGCTTTTCTACAAAATGTTAATCTCACCCGCACCACCCAACCCAGCGAAAGCAACAAAGTAAAGCCGGATGGGGTCGGATTGGCTGAAACGAGGTTCGATCAAAAGACTGTGCTGGAAGACTTTCTGGATGAGGCGTTCGAGAACAACGAAATATGGGAAAAGTACCTCGAGAATGGCGAAGAGTATCTGATCGATGATTACGATTTCTACCTGAGAAGGATAGAGGAACCGCAGCAGGAATCGGGCAAATACCCCTGCCCGCACTGTAGTGATCGTGCTTTTCCGAAGCAGTTTCAATTGATGATTCATCTGGCGGAACAGCACGATATCGCCAGTCTGGTGTGCAATGATTGTGGTGCGAGCTTTGCTAGTCTTCAGAGCTACCGCACGCATCGGCGAGAGCACATGAAGGAAAACGTTCGTTTCCGGGAGAGCAACATTCCGGAAGTGGAGGAGGCGCTATCGCTTGTGCATAGCACCGCACTGGACTATACTGTGCGCGAGGAGGAAAGCTGTTACCGATTCACCTGTAGCCTGTGTGATCGATCATTTCTGCGAAAGCACAACTTAGAAAAACACTCGTGTGCCTTCTATAAACGCCATCAACAGGAAACGGGCGAAAGACCGACAATCCGATGCCAGTACTGTGATTTCCATTCCCACCAAGCGAAGGAGGTGTTCGTCCATCAGCGAAAGCATCAAGAGGAAGGTCAGGAAAGTATCTATTGTACGCTGTGTGACCGTCGCTTTAGCTCTACGTCTGGACTGAAGTATCACCTAAAGCGGCACACAGGCATCAAAGCGTTTACGTGCCTGTACTGTGGGAAGAACTTTACCGCCAACTCGAACCTGAACGCACATATAAGGAATGTACACAGTGATCATAAATCGTTTGGTTGTCCAGAGTGTGAGGAAACGTTTGCATCGAAGGACCACCTGAACAAGCACCAACGATCACGCCATCGCCAGGAACGCTCGTTTGTGTGCGGTGAGTGCGGGAAGGCTTACTTCCAGCGTTCACATCTCAATGAACACGTAGCTGCCTGTCATCGAGAATATCGGTATCGGTGTAACGTTTGCAACAATTCATACGCTGCTCCGGGTTCCCTGAAAAggcaccaacagcagaagcatcgtATAGAATAG
Protein Sequence
MQPTLGAVLCKCCGETANKLQSLHRNVSVNGKELTVRKMFEIFLIPSEICLLEEDVVCEHCLEQLKFSYQFYDKFLEALAAATSKASAHKLDILEQTLDEVPFTCSLCDASFANNLDLEKHTKIMHSPGKHYYCAACEKHFITQRGMVQHTAAIHRDASETVSCDICQRSFTTRSNYQNHMRYHKDYVCNFCNTGWLSEASLLQHVSANHADRLFVCPFCDRKDRLRKTLNRHVRSNHQRQSCGFFCGYCGVGSTGYDNLESLNDHLKQLHEDENAPASAYEHLLNDSLFVKELPALESVDKEQEAFLQNVNLTRTTQPSESNKVKPDGVGLAETRFDQKTVLEDFLDEAFENNEIWEKYLENGEEYLIDDYDFYLRRIEEPQQESGKYPCPHCSDRAFPKQFQLMIHLAEQHDIASLVCNDCGASFASLQSYRTHRREHMKENVRFRESNIPEVEEALSLVHSTALDYTVREEESCYRFTCSLCDRSFLRKHNLEKHSCAFYKRHQQETGERPTIRCQYCDFHSHQAKEVFVHQRKHQEEGQESIYCTLCDRRFSSTSGLKYHLKRHTGIKAFTCLYCGKNFTANSNLNAHIRNVHSDHKSFGCPECEETFASKDHLNKHQRSRHRQERSFVCGECGKAYFQRSHLNEHVAACHREYRYRCNVCNNSYAAPGSLKRHQQQKHRIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00092300;
90% Identity
iTF_00092300;
80% Identity
-