Aali000680.1
Basic Information
- Insect
- Anopheles albimanus
- Gene Symbol
- ttk
- Assembly
- GCA_013758885.1
- Location
- NC:2624537-2751010[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.00018 0.0087 15.8 3.5 2 23 1474 1495 1473 1495 0.96 2 9 0.0053 0.25 11.2 0.1 3 20 1607 1624 1606 1627 0.93 3 9 0.017 0.8 9.6 8.2 1 23 1633 1655 1633 1655 0.95 4 9 3.9e-05 0.0018 18.0 1.0 1 23 1661 1683 1661 1683 0.98 5 9 9.8 4.6e+02 1.0 0.7 2 21 2162 2181 2161 2184 0.86 6 9 0.00095 0.045 13.6 2.7 1 23 2249 2271 2249 2271 0.97 7 9 1.1e-05 0.00051 19.7 2.1 1 23 2560 2582 2560 2582 0.97 8 9 1.4e-05 0.00064 19.4 0.2 1 23 2588 2610 2588 2610 0.98 9 9 8.4e-05 0.004 16.9 3.3 1 23 2616 2638 2616 2638 0.98
Sequence Information
- Coding Sequence
- ATGGGCAGTGATCATTACTGCTTGAGGTGGAACAATCATCAATCCAACCTTCTCGGGGTGTTCAGCCAGTTGCTTCAGGACGAGAGTCTGGTGGATGTCACACTCGCCTGCTCCGACGGTGCCACCATCCGAGCCCACAAGGTGGTCCTATCGGCCTGCTCCTCGTACTTCCAGACGCTGTTTCTCGACCATCCGGCCCGACACCCGATCGTCATCCTGAAGGACGTTCGCCTAACCGAGCTGCGCACGCTGATCGATTTCATGTACAAGGGCGAGGTCAATGTCGAGTACTGTCAGCTATCGACACTGCTAAAGACGGCCAAATCGCTCAAGGTGAAGGGTTTGACGGAGATGACCAACCAGAGCAGCCCGCTGACGGAGCCGAAGCTAGAACCCGAGCGACTGagagcacacagcagcagcagcagtagcggcagtaaccatcaccatcacctgcaccaccaccatggtggGAACGGTGCCAGcgccggtagcagcggcagcggggCAGCACTCGCTGCGTCCGAAGCGATACTACCGACCAACCTGTCCCGGTCGTCGCCGACAATGGCGGCGGCCGTCACcgcgaccagcaccaccatcgctgctgctgctgctgctgctgccctaaCTGCCTCGAGCGGGCTCCTCGATagtggcggaggtggtggcagtagtagcatcATCCCGAACGATAACAGTTCCTTCTCCGCTACGCCGGTCAGTAGCGCAAGCACTATCACAAGCAGCATCACgacctgcaccagcaccagcaccggcagcagtggcgcaacagtagcagcgacgacgacgacgacgacgacagcagcaacagcaacagcatcatcagctagTGAGGGTCGCGCAGTGACAACGACCGCCCAGTCGTCtcaacagccacagcatcaccagcagcagcagcagcaccctctGCTACAGCAACATCCGCATCttccacatcaccaccacacgaCGCATCACCAGCCGGCCGTCGGTGAGGTCGCTCACCATCAGTCGCAGCGTCGATCCACCAGCGCCACAAGCACGGTAGCAACCGGGCTCACCTCACCACCggccactaccagcagcagcagcagcaaccccagCAGAGCCAGCAGTAGTGGTCCCGGTGCGGACGTTGTAACGGACCTCTCAACGACGGCACCCGGCAGAAGCCGTTTGCTGGACGATAatgacggcggtggtggaccgATCGCGGCCACCTGTAGCACCAGCCGGAACAGCGGGAGTCCAGGCAGTGCTAGCGTCACCGACAGTCGGCTCACCTCACCAAACACCTGCTCAAAagccgcacagcagcagcagcagcaatcgctggCCGCGGAGAGCACTAGCACATCGACAGCTCTGCACGCCACCGCGCCCCTATCGTTGACGCGGAAGGCGCCACGTGATaccaccaccttctcctcctcctcctcagtGTCGTCTGGTAGCGGCAGTAGCATCGCTACCACCACAAACTgcaacactaccaccagcagcagcagcagcagcagcacgacggcTAGGACGTCCCCGTCGGTCGGGAGCATCTCATCGTTTCTGTCGATCGCGGCTCTAgcgaccggcagcagtagtggaGCGGCAGCGGATGAAGGCCATCCGAGGCCCCGACCGGTGATACAGAGTCCGCTTCTCCTGCAGCAGGATACGGAAGGTGAGGCGGCCAGTGTGCTGTCGTCCCAGCTGGCAGCCgcggccatcagcagcgatTCGCTAcaggaggtggtggcgggtggtggtggtggtgcccatcatcactaccatcaccatcaccaccatcatcaccaccaaccgacgCGGCATCACACGCTGCAGCGCCAGGAGGAGCAACGAAAGGACGAACTCACCTCCGACGCACTCGGTCGGCATGCAGAGGATGCAGAGGCGGAATCGGGCCTGGCCGTGGGTAGCGAAGCGACCGACCCTGGCTCACACCATTCACGGGCGACCGGTGCGAAGGGTGAGCTCGGTGCtggcggcagcaccagcaccagcaccagcaccagcaccataaGCAATAATCTCGTCCTGACGATAGATGGGCGCGTGAGTGATCCACGGCACGGGCCACCggaacggttgctgcagcaggacgaagaagacgacgacgacgatgatgatgatgatgaggaggacgacgggagagagcgaaatgaGGCAGCGGATGAAGGGCAGCGTCAGGCGCATCGTATGATTGCTgccagctccaccaccaccaccacgaccagcagTGCGCTTATCGGCGAGctaccggaccgaccggagacagccagcaccaccgaccatcatcatccactaGCGGGTAGCCCTACCGGACGGCGAAGCGGTAGCGAGCTGAGAAGTCCAACATCGAGCAGCGCGGCGCTGCGACTGTCCAGCAGCGATCTCCTGCGCGATATCGAGCAGCGGGGCGAGGAGCAGCATGGTGGACCACCAGCAACGCATCCGCTGGTGTTGCGCgatgtggtgatggcggcCGGTGCGGCTTCCGGTGCTGCGGCCGGTGCTGCGGCCaactacgacgatgacgacgacgatgaggacgaggacgagcacaACCTGcatgaggacgaggaggatgaggaagaggaagaggaggaggaggatgaggatgcgGTGGATGGGGAAACAGCGACCGCTACCGatatgctgatggtggcggctgCAGCCGCCCACGATGCGGCGACGAGTGGTAGACGGCCGCGGCGCACTGataccactaccaccaccagcagcagggaccgagaggaagaggaggtcGAGGAGCTGTTGGAGGGTGGCCGTCGGCGTGGCCACGGCCccgacgaagatgacgatgatgatgatgacgaggaggaagaggaagatgatgggCCGCACGATCTGCAcatcggtagcagcggtggccCCAGCATACTCGGTCACAGCCGTCATCTGCTGCAACtgtcgcaccatcaccaccaccaccaccatcactcacatcatcatcatcagcagcagcagcagcagctggcggccGCCGTGGCACAAACCAGTAGCGAGATGGCCGCCGAATTGCTGCGGACGGCtgaacagcaccatcagcaccgacagcagcagcagcgacaacagcatCGCCGACGGCGATCCTCCGATGAAGAAGCGGACCTACACCAACGGCGAAGAAGCGAgggtggtgtcggtgccggaaGCCGgcccggtggcagcagcagcaacaacaacagcttcagcaacaACTCCGAGGACGAGTATGAACCGCCGATGAAGATCAAGAGTGAAGTTGACTTTTCGGCCTTTTCCGGGCTAAACATGAGCCTCGCGGCGTCCGGTGGCAGCGGCTCAacgacggcaacagcagcggctgcagcagccgccgcagccgcaacaCTTTCCGCGGCCTTAAACGCTTCCgccgcatcgtcatcgtcgccgacGAGCGCCAgtgcgctgctgatgcccaCGGACCTGCGGCCCGTCTCGCGCGGTGGCAGCCTAACGGCGGACGCGCTACTAGCGGCCACCGGCAACAACACTAACTCCTCCTCGGTGGCCGCCGCCTCGTCCGGCACCaccacgtcgacgacgacaagcagcagcagcagcagcaacactaacaatagtagtagcagcaacagcggcactAACACCGGAAGCAGCGGCAAGAACGGTGACCgtgagcaccagcagcagcagcagcagcagcaagcagctcgTGGCTCACCGCAGCACCTGcatccgcaccaccatcatcaccaccatctgcagcatcaccagcggagtgcggcggctgctgcggcggccgccctGGCCGTCTTCAACTCGGGGCTCGCTAGCccgctggccaccagcgagcCGATCGCGGGCCCCTCCGGCATCATGGCACCGGTCCAGCAGGTCCCACTGTCACTGAAGAAGGAGATCGATTGGGACCGGAGCGACGACAAGTCGTCCGGTGACAGCTCGCTCGATTTCCGCCATCCGCACGACTCGGAAGCATCGGAGATGCTGCACGGAAGCGTTGGTggtatcggtgtcggtggcggcggtagtACCGGCAGCGCAGGCGGTGGTTTGGGTTTGAGTGGCACCAGTGGCGGAagcggtggtagtggcggaACTGCTactagtggtagtggtggtagtagtggaggtggtggtggtggtggtagtagtggtggtggtggtagtggtgtacTCGGTGGTAGCCTACTTGGGCTCTGTGTGCACGGGTCCGGCAGTAACGCAGCCGCCGAGGGACGGCTcgcggtcagcagcagcagtggcggtggtggtagcggtggtggtagtggtggtggcagtggcggcaacagcggtagcggtggtatCGGCCCACCCGGTCTGCTGGCCGATCATCACTCGCCGTCGAGTCTGTCGGCCGGTATGCCCATCCTGACCTGCGTCTACTGTGGCGTCACGTTCCACCACCAGAGCAAGCTGACGCGGCACATCCTATCGCACTCGCTCGAGTCGCTCAAGTACCGCGAGGCTACCCATCTGATGCACCACCACGGCCATCTGGCGCTGCATCACGAGCTGGCGCAGGTGGCGTTAGCGGCGCAGCAAGCCCagtcaccgtcgccatcgcagcAGCTACCGTCGCCGCACTATGGGCATCACCGGAGCGGAGCGCCACCGTCGCTGGAGCATCTGCTCGAGCAGACCGAGGGCATGTCGGATCTCGAGCTGGCCGCAGTACTAGCCGCACAGccggctgggctgggcatCGTTGGGccagtcggtgtcggtggcaacCCGGGCGCCGCTGGGGACCAGGGCAACAACGTGGTGCTGTGCAAGTTCTGTGGCAAGAGTTTCCCGGACGTGGCGTCGCTGATCACGCACCTACCGGTGCACACCGGTGACCGTCCATTCAAGTGCGAGTACTGCGGCAAAGCATTCAAGCTGCGGCATCACATGAAGGACCACTGCCGCGTACACACAGGCGAGCGCCCGTTCCGTTGTGGCATGTGCGGAAAGACTTTCTCTCGCTCGACTATCTTGAAGGCGCACGAGAAGACGCACTATCCAAAGTACACCCGCAAGTACTTTGCTACCTCACCGCAGCCCATCGATGGCAAAGACGATTTGCCCCAATAGTGCGACGATTTGCATCTGCTGAACTTTCTCCTCCTGTacaatctgcagcagcagcaactgcaacaacagcagcagcagcaacagcagcaccagcagcagcagcaccaacagcaacagcaacagcaacaacaactacagCATGACAATTTGCTGCGAAATCAGCAATTAAACGATCACCACAATCGTTACCAACGTCATCTGGAGCTAACCCCAAATCAGCTGtatcaacagcagccgcagttgCTGCTattacaacagcagcagcatcaactgcACACTGAGCGGTACtcactgctgcagcaacattcaccacaacagcaacagtaccagcagcaggcgcagcaacagccatcagcaaaccaacagcaacagcaaccgcagcagcaaaaggataaGGCAGATCACACTAAAAAGAAATCGCTTTCGCGCGGTTGCTGGTTCACTATTGTACAATGCCTGCTCTGGGCGCGTTTTGAGCGATCGCGTTCCACGATCGCTGCCATTTCTCCTGATGACAACCTCacgagggagggagggagggaggaagtaACCCAGTTTTTGCCAACCACCGTACCAACCACCGTTACCACCCAGCTAACACGTTTTCATTCCTtctccgtctctctttctctctttgttctgctctgctccccGTTTGCTCCACAGAATCTgagccggctgctggtgggagGAGGCGTAGGTGGGACACCGGGTGGACCACCGTACCCGCGATCCGGCATGAAATCGGCcccaccggcggcaccggccggCACCATCGGGTTCGGCTTTCCGGGGGCGGCCGTCGGTGCGATCCCGTTCGTCTTTCCCTTTGCACCGCTCGGGCTCGGTCTGTTCGATGCGGATCCGCAGCgtctgctgacgctgctgcagcaccagtcGGCGCTGGCGGAGGAAGCGCTGCGCTACCGGAACCTGCTGTTCGGTACGGTCGGTTCGGCGCCACCGCCATCCTcgtcaccaccaacggcagcatcgcTAGCATCGGGCCCGGAGGATTGTAAGGaggtgcagcatcagcagcagcatcagcagcagcagcagaaagcaacGACGGTAGCTGCAAGtaccgccaacagcagcagcagcaccggagcagGTCCACCGAGCACGATCCGCGTCCGGGATGGGCTAACGAAGGAAGGCTACCGCAACGGGATGGGCGGAGaggagctgttgctgctgcggaagcTACCGAACACggcatcaccgccaccggccggtggcacGAACCGCCGTCCGTCCTCCTGCGCATCGGACGTGGTGTGCGACGAGTCGCTGGCGCTGTTCCGCGAGACACCGGGTGCCGGTACCGAGCGCGAGCTACCACCAGGTACCACCAAGTGCCACATCTGCATGGCCCACTTTCCGTCGGTCTGGTTGCTGGAGCAGCACTCGGCCCTCCAGCATCCGCACCTTACGCTCCACGACGACAAACCGTACCAGTGCGGGCTGTGCGGCCAGAAGAGCCGCTACTCGTGCTGCCGCTACCGGACGGTGCTGGGcaagcatcaacagcaccgtGCCGGGCCCCCGCTCGACACTGGGGCGGctgcggttggtggtgcgaCGAGCCGGAGCCGGGTGCCGGCCGACAAGCTGTTCACCTGCGACGTGTGCGGCATGCAGTTCCGCTACCTCAAGTCCTTCAAGAAGCACCGGCTAAACCACGCGCTCGAGCGTCTGCACGGCAAGAAGGGAACGGTCGGTGCGCTAGTCAGCGGTCCAGggtcagcggcagcaacggtagcggctgcaccaccagcagcagcagcagcagcagcagcaaccgtcgcaGACAGCGAACCGGCCGTCTCGAGCACGAACGAACAGCCGGACACCGGTCTGGCGATGACGGCGGATGCGATTGCAGCGGATTTGCGCGGTTTGCTGCGTGATGCGGATGCGCTCGAGTCAGCGGACGATGGCGAGCAGCGGGGGGACGAGCAGGACGATACGGTGTCCGATTCGGTGGCACCGGAGCAGCCGCACACGCTCGAAGGCCCCACGAGTGCGGTTGACGTCGAGGCGCAACcgaagatcagcagcagcacgagcgccaccagcagcagcaacagcagcaacagtagcagcagcagcaccagcagcagtagcagcagtagcaacggcagcaccaccaacgggggCAAtgccagtagcaccagcatcactaGCAGCGGTGCCAAGCCGGACGATGCGActgcggagcagcagaagctccGGTACCATCCGTCGCATCAcgcgcatcagcatcacgcataccagcagcagcaccagcggcagcaccagcaccagcacctaaCCGGTTCATCGTCGCTACCGACCGTTCACTCGATGGAAGCGGAATCAAGcagtgcgcagcagcagcaccagcagcagcagcagcagcaacacaagtCCCATAGTCATACGCTCAACAGTTTGATCAACGCCGAGACGATACCGCACCATCGGCTGCTGGGGCTCGATCCGCAGGAGGCCTCGATTCTTAACTTTCTGCGCGTGGACGCGGCGGAGAAGCAGCGGGACCGCCGGTTCGCCTGCCCGTTCTGCGGCAAGTGCGTGCGGTCGAAGGAAAACCTGAAGCTGCACGTGCGCAAGCACACCGGCGAGCGGCcatttgtgtgtctgttctgTGGCCGGGCGTTCGGTGGGAAGTCGGACCTGACGCGCCACCTGCGTATCCACACCGGCGAGCGGCCGTACCACTGCGAGGCGTGCGGCAAGTGCTTCGCCCGGGCCGACTACCTCTCCAAGCATCTGACCACGCACGTGCACCAGATGTCGCCCCGCCCGTGA
- Protein Sequence
- MGSDHYCLRWNNHQSNLLGVFSQLLQDESLVDVTLACSDGATIRAHKVVLSACSSYFQTLFLDHPARHPIVILKDVRLTELRTLIDFMYKGEVNVEYCQLSTLLKTAKSLKVKGLTEMTNQSSPLTEPKLEPERLRAHSSSSSSGSNHHHHLHHHHGGNGASAGSSGSGAALAASEAILPTNLSRSSPTMAAAVTATSTTIAAAAAAAALTASSGLLDSGGGGGSSSIIPNDNSSFSATPVSSASTITSSITTCTSTSTGSSGATVAATTTTTTTAATATASSASEGRAVTTTAQSSQQPQHHQQQQQHPLLQQHPHLPHHHHTTHHQPAVGEVAHHQSQRRSTSATSTVATGLTSPPATTSSSSSNPSRASSSGPGADVVTDLSTTAPGRSRLLDDNDGGGGPIAATCSTSRNSGSPGSASVTDSRLTSPNTCSKAAQQQQQQSLAAESTSTSTALHATAPLSLTRKAPRDTTTFSSSSSVSSGSGSSIATTTNCNTTTSSSSSSSTTARTSPSVGSISSFLSIAALATGSSSGAAADEGHPRPRPVIQSPLLLQQDTEGEAASVLSSQLAAAAISSDSLQEVVAGGGGGAHHHYHHHHHHHHHQPTRHHTLQRQEEQRKDELTSDALGRHAEDAEAESGLAVGSEATDPGSHHSRATGAKGELGAGGSTSTSTSTSTISNNLVLTIDGRVSDPRHGPPERLLQQDEEDDDDDDDDDEEDDGRERNEAADEGQRQAHRMIAASSTTTTTTSSALIGELPDRPETASTTDHHHPLAGSPTGRRSGSELRSPTSSSAALRLSSSDLLRDIEQRGEEQHGGPPATHPLVLRDVVMAAGAASGAAAGAAANYDDDDDDEDEDEHNLHEDEEDEEEEEEEEDEDAVDGETATATDMLMVAAAAAHDAATSGRRPRRTDTTTTTSSRDREEEEVEELLEGGRRRGHGPDEDDDDDDDEEEEEDDGPHDLHIGSSGGPSILGHSRHLLQLSHHHHHHHHHSHHHHQQQQQQLAAAVAQTSSEMAAELLRTAEQHHQHRQQQQRQQHRRRRSSDEEADLHQRRRSEGGVGAGSRPGGSSSNNNSFSNNSEDEYEPPMKIKSEVDFSAFSGLNMSLAASGGSGSTTATAAAAAAAAAATLSAALNASAASSSSPTSASALLMPTDLRPVSRGGSLTADALLAATGNNTNSSSVAAASSGTTTSTTTSSSSSSNTNNSSSSNSGTNTGSSGKNGDREHQQQQQQQQAARGSPQHLHPHHHHHHHLQHHQRSAAAAAAAALAVFNSGLASPLATSEPIAGPSGIMAPVQQVPLSLKKEIDWDRSDDKSSGDSSLDFRHPHDSEASEMLHGSVGGIGVGGGGSTGSAGGGLGLSGTSGGSGGSGGTATSGSGGSSGGGGGGGSSGGGGSGVLGGSLLGLCVHGSGSNAAAEGRLAVSSSSGGGGSGGGSGGGSGGNSGSGGIGPPGLLADHHSPSSLSAGMPILTCVYCGVTFHHQSKLTRHILSHSLESLKYREATHLMHHHGHLALHHELAQVALAAQQAQSPSPSQQLPSPHYGHHRSGAPPSLEHLLEQTEGMSDLELAAVLAAQPAGLGIVGPVGVGGNPGAAGDQGNNVVLCKFCGKSFPDVASLITHLPVHTGDRPFKCEYCGKAFKLRHHMKDHCRVHTGERPFRCGMCGKTFSRSTILKAHEKTHYPKYTRKYFATSPQPIDGKDDLPQ*CDDLHLLNFLLLYNLQQQQLQQQQQQQQQHQQQQHQQQQQQQQQLQHDNLLRNQQLNDHHNRYQRHLELTPNQLYQQQPQLLLLQQQQHQLHTERYSLLQQHSPQQQQYQQQAQQQPSANQQQQQPQQQKDKADHTKKKSLSRGCWFTIVQCLLWARFERSRSTIAAISPDDNLTREGGREEVTQFLPTTVPTTVTTQLTRFHSFSVSLSLFVLLCSPFAPQNLSRLLVGGGVGGTPGGPPYPRSGMKSAPPAAPAGTIGFGFPGAAVGAIPFVFPFAPLGLGLFDADPQRLLTLLQHQSALAEEALRYRNLLFGTVGSAPPPSSSPPTAASLASGPEDCKEVQHQQQHQQQQQKATTVAASTANSSSSTGAGPPSTIRVRDGLTKEGYRNGMGGEELLLLRKLPNTASPPPAGGTNRRPSSCASDVVCDESLALFRETPGAGTERELPPGTTKCHICMAHFPSVWLLEQHSALQHPHLTLHDDKPYQCGLCGQKSRYSCCRYRTVLGKHQQHRAGPPLDTGAAAVGGATSRSRVPADKLFTCDVCGMQFRYLKSFKKHRLNHALERLHGKKGTVGALVSGPGSAAATVAAAPPAAAAAAAATVADSEPAVSSTNEQPDTGLAMTADAIAADLRGLLRDADALESADDGEQRGDEQDDTVSDSVAPEQPHTLEGPTSAVDVEAQPKISSSTSATSSSNSSNSSSSSTSSSSSSSNGSTTNGGNASSTSITSSGAKPDDATAEQQKLRYHPSHHAHQHHAYQQQHQRQHQHQHLTGSSSLPTVHSMEAESSSAQQQHQQQQQQQHKSHSHTLNSLINAETIPHHRLLGLDPQEASILNFLRVDAAEKQRDRRFACPFCGKCVRSKENLKLHVRKHTGERPFVCLFCGRAFGGKSDLTRHLRIHTGERPYHCEACGKCFARADYLSKHLTTHVHQMSPRP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00092248;
- 90% Identity
- iTF_00092248;
- 80% Identity
- iTF_00092248;