Basic Information

Insect: Anopheles albimanus
Gene Symbol: ush
Assembly: GCA_013758885.1
Location: NC:64725352-64784630[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0047 0.22 11.4 0.0 1 20 370 389 370 391 0.93

2 9 0.00039 0.019 14.8 0.7 1 23 459 481 459 481 0.98

3 9 0.024 1.1 9.2 1.4 2 21 549 568 549 569 0.92

4 9 0.065 3.1 7.8 3.3 2 21 1026 1045 1025 1046 0.94

5 9 0.003 0.14 12.0 0.0 3 21 1108 1126 1106 1127 0.91

6 9 0.0068 0.32 10.9 0.1 1 23 1178 1200 1178 1200 0.99

7 9 0.016 0.75 9.7 1.4 1 23 1206 1228 1206 1228 0.99

8 9 0.0097 0.46 10.4 2.4 1 23 1310 1333 1310 1333 0.95

9 9 0.13 6.3 6.8 0.7 2 20 1485 1503 1484 1505 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0047	0.22	11.4	0.0	1	20	370	389	370	391	0.93
2	9	0.00039	0.019	14.8	0.7	1	23	459	481	459	481	0.98
3	9	0.024	1.1	9.2	1.4	2	21	549	568	549	569	0.92
4	9	0.065	3.1	7.8	3.3	2	21	1026	1045	1025	1046	0.94
5	9	0.003	0.14	12.0	0.0	3	21	1108	1126	1106	1127	0.91
6	9	0.0068	0.32	10.9	0.1	1	23	1178	1200	1178	1200	0.99
7	9	0.016	0.75	9.7	1.4	1	23	1206	1228	1206	1228	0.99
8	9	0.0097	0.46	10.4	2.4	1	23	1310	1333	1310	1333	0.95
9	9	0.13	6.3	6.8	0.7	2	20	1485	1503	1484	1505	0.92

Sequence Information

Coding Sequence: atgctGCTCATCGGTATGGCCATCGAAtgccacgcagcagcatcagcagcagtcgtcgCATCAACCATGGGGGACGATGAGGATGCGGCagatgagcaacagcagcagcagcagcagcagcaaggacaGCAACATACAGTAGCGGATGCAGAAAACGGTGGCTCAACAGCTCAGGATGCAGTAGTCGGCAACGGTGacagtggcagtagtagtagcagtagtaatagtagcagtagtagtagtagcagcagcagtagcagcagcagcaacagcactcgCAGCAcgcccaacaacagcaatacAGTggtgaacaacaacagcagtcggtgtagcagcaggagtagcgcCAGTGGATGCGCTGGaatgaacggaacggatgctgTCAGTGGGTCCGCCGACCGTGCAACactcgacgaggaggaggagcaggaggaagaaggaCAAATGAGTCCAACACCATCTCGGGTGGCCAGCGGGAGTGGCGAGCAGGAAGCACACAGCGCGCGTATCCCCGGAAGACCGACATCCGATGGTGAGCGTGACGAAGAGGAAAGGGAACGGGATttagaagaggaggaggtgggCCGTGCGACGCCCTTCAATCCGTCGTTGCGTGAGATCAAGCTTGAGCCAAACGTTGACTCTAGCGCACCGGACGTCGATCCGGTCCTTGGTAGCGACCTGAGCAAGTCATCCATCACCCGGGACGCGACCCCCCGGCCGTCGACGGCCAACTCGAACGCCTCGTCCGATGCAACGACCTCGCCGACCCCAATACCGATGCTCCGGCTGAACGTGGCGCTCGCTTCGGATCCGGCCACCAATCCGGACGCCAAGGATCTCAAGGTGAACATGAACGAGGTGGAAGCGGTGGCCGCCGAgtacgcccagcagcagcagcaacagcaactagcTCTAAATATGGCAattggaccaccaccaccagccctaCAGTCAGCGCTGGTAGCGGCGgcgaccgcggcagcgactgCTTCGCGCAAAACGGCCACCGGTGTcgccggtggcgttggtggaaTGAAAGGCCCGGAAGTGATCACCGGTCCGCTGGCGATGCCACCGGTCGAGCTGCCACCCCGGTTGCCCATGTTCGTCTGTGGTCCCTGTGGTATCCGCTTCTCGTCCGCTTCGACGCTGGAAGCGCACCAGACCTACTACTGCTCCCATCGGAAGGACACGGATgaggccggtggtggtggcggtggctctgGCGGAGGATCAAACAGTGGCACGACCAGCGCAAACACGACCGGAAGCGGGCCCGGTACTGCCGCTGGTGGCACCAAGAATGCTCATCCCGGCGGAGACGGTACGACCGGTGAGCCTCCGGCCAAAGCACCCAAAACCGGTAAACAGTACGCCTGCTCCCAGTGTTCGTACAGTGCCGATAAGAAGGTCTCGCTGAACCGCCATATGCGAATGCATCAATCGTCACCGGCCACCTCCTCGGTGAACGGGGACGATGGATCGCTTCCTAGTCGCCATCAcgcccaacagcaacagcagcagcagcagcagcagcagcaactcttACAAGCACAATGCGTCGCGGTAGCGGCCGCCGCCGTACTCCGGTTACATCAACCGCAGCAATCGCAAACCCCGGTACCGGCGCAGGTCGATCGGTACTGTTCCGATTGTGACATTCGGTTCTCGAGCACCAAAACCTATCGAGCGCACAAGCAGCACTACTGCAGTTCCCGGCATCGCGAAGGCCAGCAATCCAACAACTCGACACCGAAACCCTCGGCGACGCAGAAATCGGGTTCCCAGAGTCCACCGGAAGTGCCGAAGAcaccaccggttgcggccTCACAGCAACCCTTTCTGGCCCTGCCCACCAATCCGATCATCGTGATACCTTACTCGTTAATTCGTGGTGCTAGCGTGATACCGGGCCTGCTATCCTCACTGGCACCGGGCATCACCAATCCCGAGTCGGCGTGCTTCATCTTTCAAAACGGAACCCTGCAACCGATCGCGATGTCGCTGGCATCACAAGTGCAAGCACAATCGAATGCGACCGGTACGATCGTTCCCGGGCTCGAAGGACCGCTCGGAGGATCGCAACCACAtccagcaacacaacaccaacagcagcagcagcagcaaccgcagcaaagGTCCGCTTCAAGTGGAGGCAATCAACGACCGCAGTCCCGCGATACGACACCGAATGCTTCGAACGAAAACAGTTCCCACAGCATGGCTGGTGGGGCAGCTGCCTCTTCGACGGGTGAAGTGCTTAAGGCAATCAACAAGCGGGACAACACAGCCAACAGGGATGGTACGGGATTGACTTCCACTCCACTGGATCTATCGGTGAGGCGGTTCTCGCCGCACGGTGCCATGGCGAGCTTACGCGAacgttcgctctcgctctcgtcggCCATCTCCGGCGATCAGCGGATCGACTATGACAGCCTGATGGAGGGTAAGGAGAACCTGTCCGTCAGCGGTGATTCGATAACGCCGGAACAGATTGTCTGTGCACCGTCGTTGCCGGGGAGTCCACCGCTAACGCCGTCCCCGAAGCGTCGCTCCAATAGCCCTCGTGCCGCCGGTCCAATGGCATCCAGCGCGGCAATGGCAGCTGCAGCGGTTGCTAATCAGCAatcggcagctgcagcagcagcagcagcggcggcagcccTTGGCGGGCcagtcgctgctggtggcgtagGAGGTGGACTATCGATCTCACCATTgacgctccagcagcagctgatgcggCCACTACTGCCAGCCGATATCGCGCTGCGCCTCTCGGCCGTCGGTGATCCTGGCGTTAATCTGAACCTGAATCTGCTGCCCAGCGCACATCCACTGCTAACGAAGCAGGGTGTGGAGTTGGCGCTGCGGCTATCGTCCGGTACACCGAACGCCTCGAATGCCATCGATAAAGGGTCGCTACAACCACAGATGTCACCGCTGCTGAACAGTATCTCTCCGACGGCGGCTGGTCCAGGTGCTACAGGTGCTGGGGGTGCCACCGGTGTAGGAGCGTCCGTATTGggttcaccagcaccgcagATCTTCGTCAAGCAGGGTGACTCCAAGTGCAAGGAATGTAACATCGTGTTCTGCAAGTACGAGAACTATCTCGCGCACAAGAAGCACTACTGCTCCGCCCGAAATCAGGATCAGGAGGGGGGTGATGGTGCGGCCAAGGTTAGTCCGCCCATCTCACCACAGGCTGGTACGGCAGCGGGTGCCAGTCCATCGGCAGcggtcgcagcagcaggcccggGATCGAGGGTacccggtggtgccggcaaTCAACCTCCGTATCATCAGCTGATCTGTGCCGCCTGTGGCATCAAGTTCACCTCGCTCGACAACCTTACCGCCCATCAGATGTACTACTGTCCGAAGCGCATCGACATCAATCTGCCTGTGAGTGCTCCATCAGCAACGAtcgctccggcaccggcaccacacaAGGAACGGTGTTCCAAATGTAAAAGTATGCACGAACCCGGTCAACCATGCACGGTCGCTGGACATGGGGCGTACAAGTGTCCCCTGTGCGAGGTGATTAGTCCCAACTCCACTGAAGCTCGGCGTCATATGGATACACACGGTGGTGTGAAAGCGTTCCGCTGCACCATCTGCCGGTACAAAGGCAATACACTGCGTGGTATGCGTACACATATTCGGATGCACTTCGATAAGAAAACGAACGAGTTCAATGAGGAGAACTACATCACGTGTATCCTGGAGGAGGATGGTATCGAGATTCCGCCAGCTGGTGGTCAGAATGCTGCagccgtggcagcagcggccgcagcgcTTGCCTCACCAAACCACACGTTTCTCGCCCAGGATGcggctgccgttgccggtgtAGTGACAGAGGGCTCAAGGACTTCACCACCTTCGGCTGGTAATGGTGGTCCAGCGGTCAGACATCACTGTGAGCTGTGCTCGTACTCTACGAGCGATCGAGGCAACATGGCTAAACATATCAAACAAGCTCACGGAGGCGTGCGACGCTCACTTGGAGTGAATTCTAATGATGGGTCTCTGGTGTACAATGGGATGGTAGAGTCGAGGCCTCCGATCGTTAGCACACCTGGGCCGATTGCGGGCAATAGTCACATCAAAACGGAACCAGTTGATGATCatgaggcagcagcaaactcaGCTGTAGACGACCAGGACACGGTCGATATCAATGTCGATGTCATCATGGAGGAACCGAGAGTGCCGGCCATTAAGACGGAAGTCATGGATCCGCATATGCCATTACTCAACTCCCCGCTAGCCTCCccagcaccgccatcaccTGCTTCTCAGAATCTGAAAACGAAAtctcaaaaccaaaccgaaccgatggaaCCAATGTCGTCGCCACCGGCTAGAACGGTCACAAAGACTccgtcaccaccgtcggtggacctccagcaccatccgATGCTGGCGGGCCCAAAATACTGCGACACTTGTGACATCACCTTCAACTATACCAAAACATTCATCGCGCACAAAAACTTCTACTGTAAGGCACTCACTAGCGGTGCCActggggctggtgctggtcccgGAGggatgattgctgctgctgctggtggtggtgtagctTCAGTGAGCGGTGGTGGCATTCGTCGAAGTACATCAGCTTCACCTAATCGGGCGGCCACTGCGGGGGGAGCTACAAGTCCAGTCGTCACGGTAGCCGTTAACCGTGCAACGGAAACGTCCGTTTAG
Protein Sequence: MLLIGMAIECHAAASAAVVASTMGDDEDAADEQQQQQQQQQGQQHTVADAENGGSTAQDAVVGNGDSGSSSSSSNSSSSSSSSSSSSSSNSTRSTPNNSNTVVNNNSSRCSSRSSASGCAGMNGTDAVSGSADRATLDEEEEQEEEGQMSPTPSRVASGSGEQEAHSARIPGRPTSDGERDEEERERDLEEEEVGRATPFNPSLREIKLEPNVDSSAPDVDPVLGSDLSKSSITRDATPRPSTANSNASSDATTSPTPIPMLRLNVALASDPATNPDAKDLKVNMNEVEAVAAEYAQQQQQQQLALNMAIGPPPPALQSALVAAATAAATASRKTATGVAGGVGGMKGPEVITGPLAMPPVELPPRLPMFVCGPCGIRFSSASTLEAHQTYYCSHRKDTDEAGGGGGGSGGGSNSGTTSANTTGSGPGTAAGGTKNAHPGGDGTTGEPPAKAPKTGKQYACSQCSYSADKKVSLNRHMRMHQSSPATSSVNGDDGSLPSRHHAQQQQQQQQQQQQLLQAQCVAVAAAAVLRLHQPQQSQTPVPAQVDRYCSDCDIRFSSTKTYRAHKQHYCSSRHREGQQSNNSTPKPSATQKSGSQSPPEVPKTPPVAASQQPFLALPTNPIIVIPYSLIRGASVIPGLLSSLAPGITNPESACFIFQNGTLQPIAMSLASQVQAQSNATGTIVPGLEGPLGGSQPHPATQHQQQQQQQPQQRSASSGGNQRPQSRDTTPNASNENSSHSMAGGAAASSTGEVLKAINKRDNTANRDGTGLTSTPLDLSVRRFSPHGAMASLRERSLSLSSAISGDQRIDYDSLMEGKENLSVSGDSITPEQIVCAPSLPGSPPLTPSPKRRSNSPRAAGPMASSAAMAAAAVANQQSAAAAAAAAAAALGGPVAAGGVGGGLSISPLTLQQQLMRPLLPADIALRLSAVGDPGVNLNLNLLPSAHPLLTKQGVELALRLSSGTPNASNAIDKGSLQPQMSPLLNSISPTAAGPGATGAGGATGVGASVLGSPAPQIFVKQGDSKCKECNIVFCKYENYLAHKKHYCSARNQDQEGGDGAAKVSPPISPQAGTAAGASPSAAVAAAGPGSRVPGGAGNQPPYHQLICAACGIKFTSLDNLTAHQMYYCPKRIDINLPVSAPSATIAPAPAPHKERCSKCKSMHEPGQPCTVAGHGAYKCPLCEVISPNSTEARRHMDTHGGVKAFRCTICRYKGNTLRGMRTHIRMHFDKKTNEFNEENYITCILEEDGIEIPPAGGQNAAAVAAAAAALASPNHTFLAQDAAAVAGVVTEGSRTSPPSAGNGGPAVRHHCELCSYSTSDRGNMAKHIKQAHGGVRRSLGVNSNDGSLVYNGMVESRPPIVSTPGPIAGNSHIKTEPVDDHEAAANSAVDDQDTVDINVDVIMEEPRVPAIKTEVMDPHMPLLNSPLASPAPPSPASQNLKTKSQNQTEPMEPMSSPPARTVTKTPSPPSVDLQHHPMLAGPKYCDTCDITFNYTKTFIAHKNFYCKALTSGATGAGAGPGGMIAAAAGGGVASVSGGGIRRSTSASPNRAATAGGATSPVVTVAVNRATETSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00098620;
90% Identity: iTF_00098620;
80% Identity: -