Basic Information

Insect: Anopheles albimanus
Gene Symbol: mecom-b_1
Assembly: GCA_013758885.1
Location: NC:73517601-73618642[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00042 0.02 14.7 0.1 1 23 401 424 401 424 0.96

2 8 0.00012 0.0055 16.5 0.3 8 23 473 488 472 489 0.92

3 8 2e-06 9.5e-05 22.0 1.7 1 23 495 517 495 517 0.95

4 8 4.1e-05 0.0019 17.9 6.0 1 23 523 545 523 545 0.99

5 8 0.0093 0.44 10.5 0.6 2 21 553 572 552 573 0.95

6 8 3.4e-08 1.6e-06 27.6 1.2 1 23 1296 1318 1296 1318 0.99

7 8 2.2e-06 0.0001 21.9 1.6 1 23 1324 1347 1324 1347 0.97

8 8 0.00019 0.0089 15.8 6.7 1 23 1353 1375 1353 1375 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00042	0.02	14.7	0.1	1	23	401	424	401	424	0.96
2	8	0.00012	0.0055	16.5	0.3	8	23	473	488	472	489	0.92
3	8	2e-06	9.5e-05	22.0	1.7	1	23	495	517	495	517	0.95
4	8	4.1e-05	0.0019	17.9	6.0	1	23	523	545	523	545	0.99
5	8	0.0093	0.44	10.5	0.6	2	21	553	572	552	573	0.95
6	8	3.4e-08	1.6e-06	27.6	1.2	1	23	1296	1318	1296	1318	0.99
7	8	2.2e-06	0.0001	21.9	1.6	1	23	1324	1347	1324	1347	0.97
8	8	0.00019	0.0089	15.8	6.7	1	23	1353	1375	1353	1375	0.99

Sequence Information

Coding Sequence: ATGCGTTCCAAATCTGTTGCCAGGCGGTTCGCTCAAGGCATCAGTGGTGACGACGCAGTGAGCGCATCCCGTGGACTTCCAGCAAAACTTGAGGTGCCTCCGGGGCTGCAGGTGATACCGATGGGCAAACACCACGAGCACGGTGCACCGGAGCTCGGTCTATCGTTCGGccaccacctgcaccatcATAACCTCCAcaaccaacatcatcaatACCTTCCATCGACGGAGGAGGACATCTGTGAAAGGTTAAAGAACACACaggagctactgctgcagatggCCCGGCTACAGTGTCCACCGCCGGATCTGGACGTGCAGACCGGCTCGGTCGTCGCGCTCAAGACAATCCCGAAGGGCACCCAGTACGGACCGTTCGTTGGGAAGCTGGTGCgggaaccgatcgatcggcggtACGCCTGGGAGGTCATTGGCTTTGACATGCATCGCTGGTTGGATGCGACGCTGGATCCGACGAACTGGATGAAGAACATACGCTCGATATCGAACTTGGCGGAAGTGAACTTGCAGCACTTTCTGAACGATGGTCATCTGTGGTACGAAGTGATATGTGACATCAGCCCCGGCCGGGAGCTACTGTTACGCCCGAAGGTTCCTCTGCATCCGCGCGACGGTCAGGACGAGCGCAGCGACCGTGGCTCCGGCGGTTCACAGCACAGCGAAAACTACGAGGACGAGTACAACACATCGAACGATCTagacgccagccagcatcagcaccagaaggagcatcagcagcagcagcagcagcatcacaaggAGCACCTTAACAGTAGcgtcaacagcagcggcagcagcagcagcaacaacagccgaagcagcagcagcagcctcggtGGACGCCCATCGAACCGGGGTACCGTGGACGGTGCCTCCGGCAGTCGtagccggagcagcagtagcaacggtCCGGTACGCCGCCAGCGGGCCAGTAGCCGGACGAGTAacgcggcggctgctgctgcggcaccgAACGGTGCAGCATCGAGCGGAGCGGACCAGCAGGACGAGCACTGCGACGGCAAGAACGGtggtgacggcggtggtgaggacccggaggaggacgacgaagacgtcGAGGGTATCAACACACGGTGCATCGTCTGCGAACGTCAGTGTCACGATATCGAACTCCTCGACGAACATCTGGTAAATGCGCATCACTACCAGAAGGACGCGTACCGGTGCGATCTTTGTCCGCGAGCCTACAGCTACCGGCCCTCGCTGCTACGCCACCGAGCGATCGTCCACGGTGAGCTACGGCGCTTTCACTGCGAAAACTGTCCCAAGCACGAAGAGACCGAGGCGGcgagcactggcactggtcTGCCGCCATCGGGCGCTTCCGCATCAGGCGAACTGTTCAGTTACCTTCTGCAGCACGCTCACGATCCTAGGGTTTTCACTGATCCGTCGAACCTTCAGCGTCACATCCGGACGCACCACGTGGGCGCACGGAGTCACGCATGCCCGGAGTGTGGCAAAACGTTCGCAACCTCGTCGGGGCTgaagcagcacacgcacatccACTCGTCGGTGAAACCGTTCCAGTGTGAGGTGTGCTTCAAGTCGTACACGCAGTTCTCGAATCTGTGCCGCCACAAGCGCATGCACGCCGACTGCCGGATGCAGATCAAGTGCGACAAGTGCGGCGACAGCTTCAGCACCGTTACGTCACTGTCCAAGCACAAGCGCTTCTGTGACTCGACCGCCGTGACCCGGGCCGGTCTCCATCCGAACGCTCTGCACcttcctcaccatcaccatcatccgaatcatcatcagcaacagcatcagcagcagcaccagcagcagcagcatcaccatcatcaggcaattgctgccgctgcggccgccgctgctgctgcatcgcagcatcatcatccgctggCGCcacatcatccgcatcatcgaCAACAACCGGGTGGTGGATCTGGCCAGCCCACCGTCACTGGAGgaccagcaggaggaggaggagtcgCACCGCCCATCCCTAGCCTGCCACCCAGCATGACGACGCCACCGAACCCGTTTCTGATGTTCCCGGGCTCACCGTTCTTTGCGCCCGGCTTCCGACCACATCCCGGTCTGCCGGGCATCTTtccaccggccggtgccggtggccaggtGTCCCCGTTTCCACTGTCCTTCTTCCCGAAGCTACCGAcactcggtgctggtggtctcgTCGGTGGACTGATGGGCGAGGCGGAACGCAAGacaccgtcgccgccactgAAGCGAATCCTCGACACCGCGTCCGGTGCTGATCGTGGATACGGTGGCCAGCAATCGATGAAGATCTCGCCACCGACGGCACAGGAAGCGACGAGCCCACAGCGACCGTCACCGGCGCGACCGACCGCGATGACGGCCACCAATCCGGTTGACTTTCGGTTGCATGACGCACCGTCCGCCTTGCTATCGGGATCGTCATCCTCGGGCGGTGGATCACCGCGTGGCATGAATGGTGGAGAGGGGCAATCGGAGGccccgaacagcagcaacagcatcaccaccaccaccaccaccaccaccaccaacaacaacaatcacatTAAGGAGAACAACAATCACGCCGGTACGAATGgacgcagcaggagcagcagtagcagcaacagaagccgCAACGGTTCGCCCTATCCTCAGCAACCGTCGCGCTTGACGAACGCTagaagcagccgcagcagtacgggcagtagcagcaggggCAGTTCGGTTGGGCGTGCGGAAGAGACTCCGGtcgccggtgacgatggtgccgCTCGTTCGACGTCCATTCGCGTTAAGAACTTTTCGCTCCGTTCCTCGAGCAAGGCCATCGACGTCGAAGACGAACAGGTGCGGCGTCGTCGCACTCCAATGAAGTCGCCCATTGACCAGCCAGCCGTTTCACCGGTTTCCTCGACGACGCGACGTCGAAGCCATACCGTGCACGAAgggcagcaggatgatgatataTCCGATACGGAGGAGCACTTCGAGAGTGGCGGCAGTTCGGCGAAGAAGatcaaaaaggaagaggaagcgacggtcgctggcgttggcgctggtggtgagcaGCCGTTGGATTTGAGTCTCTCGAAAAAGTCCTCGAGTGAGGCCGGGGATtcgaccggcggtggtgctgccggtggactGGAGCAGGATgtggatgatgaggaggataaTCGCTCGGGCCGCAGCGCGACACCGATCGAGGTAACGAGTCCGGCACTGACACCGACACCATCCGTACCGACACCGAGCTCATCGTCCGAGGCGAACgatcaccagcatcgccatcaccaccaccaccgaagccgTGGTGAGCGTGGCCCTGGACGGAAGACGGCTTCCGCTTCTCCGGCGTTTGTACTGCCGAGTCCATCACCGTCATTGTCACCGCGgccatcaccttcaccgtcgtcaccgggcagtcagcagcatcaccttcatcaacagcagcagcagcagcagcaacatctccagcaacaacagcagcagcagttgcaatcacatcatcagcagcagcagcaaccacatcAACCCATCCCGTATCCTCAGCCAATCTATCCGACGCTGCTGGATGTGTGGAAGATGTACCGTGGTCCGGAAGCGATGGCCGGTTACCAGCGGCCTGCCTTTAACTTTGGCGACTCGAGCTCATTCGACTCGAATCCACTCAGTGATCTGCTGAAGCGTAGCCGTCCGTACGGTGCAGCGGCCAAGTCCTTTCATCACGCGATGGGTCTCggtcctggtggtggcgctggtgccgtCGGTACTGGTGGACTTCCAGCTGGattcggtgttggtggtagccTTGGACCGaatggtgccaccggtggtggtgcagggcTCGTTGGGAAGGTGAAGGATCGGTACTCGTGCAAGTTCTGCGGGAAGATCTTCCCCCGGTCGGCCAATCTGACGCGCCATctgcgcacgcacaccggcgaGCAGCCGTACAAGTGTCGGTACTGCGAGCGttcgttctcgatctcgagcaaCCTGCAGCGCCACGTGCGGAACATCCACAACAAGGAGCGCCCGTTCAAGTGCCATCTGTGCGAGCGGTGCTTCGGCCAGCAGACGAACCTCGATCGCCACCTGAAGAagcacgatgccgatgcgtCAGGGTTGGGTATTGGGCTGGGCGATTCACCTTCCTCGAACGAGGCCGAACGGGGGGACGATGTGTTCTTCGATGAGATTCGCTCGTTCATGGGCAAGGTGACGTACTCGGGACCGAGCGCGCTGCTAGCGGCCAGCGCTAACGGATTGATCGGGTCGGATAAGGCCGGGCTGGGGCTTGgcctcggcatcggtggcggtggtggcgttgttggagaggacgatgatgatgagatcgGTGGCAGGCATTCGGCGTTCGCGACGACACCGATCGATGTGACGCGGCTCGATGCCGGTGAGGAGGACGGTATGgtggatgaggaagaggacgaggagggACGCGAGGAGATGGAGGATGGAGGTGAGAGGGCCGGAAGCTGCGATCGGGACAGTGATCTCATCAACATCGAATCGGACAAGGAGCTGGGCGCTAGCACCAATGATGCGATCGATGTTTAG
Protein Sequence: MRSKSVARRFAQGISGDDAVSASRGLPAKLEVPPGLQVIPMGKHHEHGAPELGLSFGHHLHHHNLHNQHHQYLPSTEEDICERLKNTQELLLQMARLQCPPPDLDVQTGSVVALKTIPKGTQYGPFVGKLVREPIDRRYAWEVIGFDMHRWLDATLDPTNWMKNIRSISNLAEVNLQHFLNDGHLWYEVICDISPGRELLLRPKVPLHPRDGQDERSDRGSGGSQHSENYEDEYNTSNDLDASQHQHQKEHQQQQQQHHKEHLNSSVNSSGSSSSNNSRSSSSSLGGRPSNRGTVDGASGSRSRSSSSNGPVRRQRASSRTSNAAAAAAAPNGAASSGADQQDEHCDGKNGGDGGGEDPEEDDEDVEGINTRCIVCERQCHDIELLDEHLVNAHHYQKDAYRCDLCPRAYSYRPSLLRHRAIVHGELRRFHCENCPKHEETEAASTGTGLPPSGASASGELFSYLLQHAHDPRVFTDPSNLQRHIRTHHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKSYTQFSNLCRHKRMHADCRMQIKCDKCGDSFSTVTSLSKHKRFCDSTAVTRAGLHPNALHLPHHHHHPNHHQQQHQQQHQQQQHHHHQAIAAAAAAAAAASQHHHPLAPHHPHHRQQPGGGSGQPTVTGGPAGGGGVAPPIPSLPPSMTTPPNPFLMFPGSPFFAPGFRPHPGLPGIFPPAGAGGQVSPFPLSFFPKLPTLGAGGLVGGLMGEAERKTPSPPLKRILDTASGADRGYGGQQSMKISPPTAQEATSPQRPSPARPTAMTATNPVDFRLHDAPSALLSGSSSSGGGSPRGMNGGEGQSEAPNSSNSITTTTTTTTTNNNNHIKENNNHAGTNGRSRSSSSSNRSRNGSPYPQQPSRLTNARSSRSSTGSSSRGSSVGRAEETPVAGDDGAARSTSIRVKNFSLRSSSKAIDVEDEQVRRRRTPMKSPIDQPAVSPVSSTTRRRSHTVHEGQQDDDISDTEEHFESGGSSAKKIKKEEEATVAGVGAGGEQPLDLSLSKKSSSEAGDSTGGGAAGGLEQDVDDEEDNRSGRSATPIEVTSPALTPTPSVPTPSSSSEANDHQHRHHHHHRSRGERGPGRKTASASPAFVLPSPSPSLSPRPSPSPSSPGSQQHHLHQQQQQQQQHLQQQQQQQLQSHHQQQQQPHQPIPYPQPIYPTLLDVWKMYRGPEAMAGYQRPAFNFGDSSSFDSNPLSDLLKRSRPYGAAAKSFHHAMGLGPGGGAGAVGTGGLPAGFGVGGSLGPNGATGGGAGLVGKVKDRYSCKFCGKIFPRSANLTRHLRTHTGEQPYKCRYCERSFSISSNLQRHVRNIHNKERPFKCHLCERCFGQQTNLDRHLKKHDADASGLGIGLGDSPSSNEAERGDDVFFDEIRSFMGKVTYSGPSALLAASANGLIGSDKAGLGLGLGIGGGGGVVGEDDDDEIGGRHSAFATTPIDVTRLDAGEEDGMVDEEEDEEGREEMEDGGERAGSCDRDSDLINIESDKELGASTNDAIDV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -