Aali004461.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Anopheles albimanus
Gene Symbol
-
Assembly
GCA_013758885.1
Location
NC:15897515-15905268[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.9e-07 9.1e-06 25.2 0.3 1 23 291 313 291 313 0.99
2 15 0.058 2.7 8.0 0.5 1 23 319 342 319 342 0.98
3 15 6.6e-05 0.0031 17.2 0.3 3 23 364 385 362 385 0.93
4 15 0.04 1.9 8.5 3.0 1 23 391 414 391 414 0.91
5 15 8.4e-05 0.004 16.9 0.6 1 23 623 645 623 645 0.98
6 15 2.2e-05 0.0011 18.7 0.3 1 23 651 673 651 673 0.99
7 15 0.017 0.83 9.6 3.9 1 23 783 805 783 805 0.98
8 15 3.7e-05 0.0017 18.0 0.8 1 23 811 833 811 833 0.99
9 15 1.4e-05 0.00068 19.3 0.1 1 23 929 951 929 951 0.95
10 15 0.00069 0.033 14.0 1.5 1 22 957 978 957 981 0.90
11 15 6.6e-07 3.1e-05 23.5 0.8 1 23 1160 1182 1160 1182 0.99
12 15 8.3e-07 3.9e-05 23.2 1.8 1 23 1188 1210 1188 1210 0.99
13 15 0.00088 0.042 13.7 2.9 1 23 1495 1517 1495 1517 0.98
14 15 1.8e-06 8.5e-05 22.2 2.6 1 23 1523 1545 1523 1545 0.99
15 15 0.051 2.4 8.1 3.2 2 23 1561 1583 1560 1583 0.94

Sequence Information

Coding Sequence
atgaTGAGCCAAGCATCTAGTAGccgcagtggcagcggcaacagtaTCGAGCtgaaaacggaacgcaaagATAATGGCCTGGAgcgcgaagaggaggaggaagaggagggggAAGgcggcgacgaggacgatgctggtggtgtgaaggaggaggaggaggaggaggagcagcagcagcagcagcgcgagggTCACACGACCACCGACGACGCCCACCAGCTCGCGGATGCGGGCAACTCGTCGGATCTCGAGATAGTCGTCGGTATCGATGAGGATCACATCAAGTTCCTCACCAGTATGCACTCGGGCGACGACGAACCGGCCCACAATGGGCaccattccggtgccggtggtgataCGGTACGCGGGCCGGGCGCATCGACGATGGCAGTGGACCGGATCCGACGCCGTTCCGGTAGCGTTGGTGgcccgtctgctgctgctactactgcatcACAGAATGGCAGTGGCCGTCGACCGACCGCTCACAAGCTCACACAacgtaagcagcagcagtccgggttgctgctgcatcatcatcattcccatCGATTGAATGGCATTTTCAACGGAAATGGTAAAGCAGCACGGCGCCGGATGCCCGGAGGaggagcggtggtggtggtggagggacAGAAGACCGGTAACggagccggcagccggcagcagctcaCCTTCACCGATGACGATTCCGCCgccgatgacgaggacgatgaagatgaggacgatagcgatgaggaggacgacgacgatgacagcgatgacgacgatgaggacgatgacgatgaggacgtgATGGCGGAGGCTGCTACGATCCTTTCCAAGACGGCccagcaccgatcggtggccagtggTGCCGAGTCCCGCCGGTATCAGTGTGATTTGTGTCCGCGGGCGTTCGCCAGGCCCGACTACCTCCGCTACCATATGCGGACACACGAGAAGAGCAACTCGTTCGAGTGTAAGCTGTGCTTTAGCATCTTCGCCTCCGATCCGGCCTTCGCACATCACATCCGCACCGAGCACGCCGGTATGGGGCTGGCCGATGCTCTGCCGCCGGTGCCCGAATCGGAGGCAAGCCGCGTCATCTGTACGTACTGTGATCGGACGTTTGCGGATGCGGACCAGCTCGAGGAccatctgcaccagcagcatctcggAGTGCGGCCGTTCAAGTGCAACATGTGCCCGAAGGCGTTCATCCGGATGGACTTTCTGCAGTGCCACTACGCCAAGTATCACAACTTTCACCGGCTCAGCATGATGGGGctgggcgatggtggtggtattggtggtggtggtggcggaggcggaggcggtggtggaatgaaTCATCCCCTCGATCCGATTGATCGTGCCGTTCAGCGGGCGGCACTGTGGAACAGTGGATTCCTggccagcggcggtggtggtggcggcggcaacaCCCAGGGAACCCATGGACGCCAGGACACGTCGGCAGCACCGGGAGTGCCAAGGTTGGCGGTGCGGAAGATGGAAGATCTGCTCGATGGTCCCAGGAGAATcgctcccggtggtggtggtggtagtgtggcCCCCATGGGGCTTTATTCGCGCAGAACGTCGCACACGACGGGCACCACGATTGGTAGTAGCTCGAGCGACGataacgacgaggacgacgatgaggacgagctgAAGATGGTGGTCGTGTTGGGGGAtgaggatggcgatgatgagggTACGGGTGCGGAGAGTAATGGGCAGCGAAAGCGGAAGCTCACCAACGGCGCACACAGTGTGCGTTCatcagcgaagaagaagaagcgagcgaCGATCGGTGCGGAGGCTGCTCCgttaccggtggccaccgttcccgCCGCCCCCGAAGCAGAAACCGGCAAGCATCGGTGTCCGGTTTGTGAGCGACGGTTTGTCCACGAACCGGAACTGATGGTACACGTGCGCGTACACCCTGATCTACCCACCTACAAGTGTCCGCTGTGTGAGCTCACGTTCATCGGTTCGGATTACTTGAAGGCGCACCTTAAGAAGCACGTCGTCGGTGACGGCGAAGATCCGAATGCgcccggtgcgatcgatctgaAGGCGCCCGTGGAGACAGTTTCcacggcaacagcaccagcaccagcgccagcttCCTCTCGAACGTCCATTACTATGTCACCTGCACCGTCTGCCCTGATTGCTAGCAAATTCCCGAAGATTGTATCGAAGGTACCGTCGACGGGCATTTCACTGTTGAAGCCCCTGGAAGAGCGGAAACCACCGGatcagcagccacagcagcagcagcagcagcagcagcagcagcagcagcaccaaccatcCCAGGAGTACTGCACCAAAACTGCCGACGGCAAGTTCAAGTGTACCGTGTGTGAGCGGCTCTTCTCCCACCAGCAGACGGTACGCATCCACTTCCGGAACCACACGAACGAGAAGCCGTACAAGTGTGCGTTCTGCACGGAATCGTACATCCGGTCGGACTATCTGGAGCGCCACCTGAAGGTACACTTCAAGGATGGTGTACTGCCGGCGAACGCGATCGCCAGtatggcggcggccgctgctcgTGAAGCGGCAGCCGCCGTCGCCCTCTCGAACGGTACCGGCGGAGGAGGTCAACGGTTGTCGCTTCCATcgtcaccaacaccaccaccgctagtGACGGCTCCTGCGGTGAAGGAAGATGTGAAGCGCGAGGTAACGCCATCGACGACCCCGACCCCGAAGCCACTGATCGGGCGGGCTGGGCTCGCGCCGGAGAACTACCACTTTGCCGAGTCGAACGATGGGCAGTACGTGTGCAAGATCTGTGACAAGGTGTTTGCGCAGGTGGCATCGCTGCGGAAGCACGCCCTGGCACACAATGAGGAGAAACCGTTCTACTGTGAGGTATGCGATCGTTCGTTCATCCGGGTCGACTACCTGAAGGAGCACTTTAAATCCAAACGGCACCTGCAGCTGGTATCGGAAGGGTTGATCGGATTGCGGGAGGTCGAGGAAGACGATTCGACCATGGACGGTGGAGGATCATCCCGGTCGCGCACGGCACCGCCGAAGCGCCGTAGCAAACCGGGTGATAAGAGGAAGGCGACTGATGCGctgaccggtgctggtgaggCAACGGTCGATACAATCCACCCAACGCTACTAGCGGCGGCCAACTGTGGCAATAGCCGGTGCAGCAGTACCAGTAGCACCGGGagtagcggtggcagcagcagtagcagcagtagcggcagcagcagcggtggcagcataagccgcagcagtagcgcttGCGAGGTGGCCATCATCGAACACACGCCGACGAAGCTGGTcctgaacagcagcagcaacagcaacggtgcGGTACAAACGCCTCCATCGGCCGGCGAACAGCATCcccagcagctgcagttgcaaaaggcgacgacgacgacgcccggTTCGGCGGGGACGACACCCGAGTTCCATCGGTCCGATTACGAGCGCACCTCGGACGGGCGGTACAAGTGTAATCAGTGCGACAAAACGTTCGTCACGGCGGTCACGCTCAAGATGCACATCCGGCTGCACACGGGTGAGAAACCGTACAAGTGCGACAAGTGCGATAAGGCGTTCATACGCTCCGATTATCTGAAGACGCACGAGAAaacgcaccggcagcagtcgTTCCTCAGTTTGCTGGCGTTGACCTCGAAGGAACCGAGCACGGCCTCCGAGGCGGGCGATGATTCGGATGCCGGCGGGGAGGGTGCACGAACGCCCGCCCCGGgcaacgatcacgatcatcggCACGAGTCGGTGACGACGTCGGTCGGCGGGGGGCGATCCTCGCTGCTAGCGGACAATACTGCTGATGGGAGGGAGGCCATCAAGCGAGAAGGGCGACAGGGCAAAGGTgtggaagaaggagaagtgaTCGATGACGCAGAGGAGGATGctgaggaagaggaggacgatggaGAGGATGGTGATCCTTCGGAAGACAGCGAAGAAGGCGAAgcggaggacgaggaggaggaagaggaggatggGGCGCAgGTCATCAAAGTAATGGTCAAGGAGGCGAGCTGCGAGTCGGAGAGCGAAaatgaggacgaggaggaggaggaggaggtcgatgacgaggaggacgaggaagaggaggaagaggaagggacgggcgaggaggcggaggagcgGGCCAGCAAAAAGCATttcagcgccagcaacagtaCAATTGATCTTCCAGATCGCGAATCAGCCGCCACTGTCAGCCTGTTGCTGCAGCGTAATCGCGCACAGCCATCCGCGGGCCGCGAAGTAGCGGGAGCGAAGGAGGCACGGGCCGGTTTCCACAGTAACCGCGGCAGCATTGTCAGTGGCGGAGAAAGTAGCAACAATGGCTACGAtgatcacgacgacgatgacagtgCATCGCAGACGAGCGACGGGCAGCGACtggcgaatggtggtgctagtggtggtggtagctaTTGGGCGCAAGGAGGCGACCCTAGGCCGGACAAGCACAGCTGCCCCACCTGCCACAAGCTGTTTGCATGGCCGAAATCCCTGAAGATCCACATGCGTACCCACACCGGCGAGAAGCCGTACCGGTGCGACGTGTGCGGCAAGTGCTTTGGCCGATCGGATAGTTTGCGTGGGCACAAGCGCACGCACTCcgaggagcaccagcagcagcagcagcagcagcagcggattaTGCAGTGCCATCTGTGTGATTTGTGTTGTACGAACGGcgagcagctggtgcagcatcagctcgcGGCCCACGGTATTCAACCGCTAGAGTGCTAG
Protein Sequence
MMSQASSSRSGSGNSIELKTERKDNGLEREEEEEEEGEGGDEDDAGGVKEEEEEEEQQQQQREGHTTTDDAHQLADAGNSSDLEIVVGIDEDHIKFLTSMHSGDDEPAHNGHHSGAGGDTVRGPGASTMAVDRIRRRSGSVGGPSAAATTASQNGSGRRPTAHKLTQRKQQQSGLLLHHHHSHRLNGIFNGNGKAARRRMPGGGAVVVVEGQKTGNGAGSRQQLTFTDDDSAADDEDDEDEDDSDEEDDDDDSDDDDEDDDDEDVMAEAATILSKTAQHRSVASGAESRRYQCDLCPRAFARPDYLRYHMRTHEKSNSFECKLCFSIFASDPAFAHHIRTEHAGMGLADALPPVPESEASRVICTYCDRTFADADQLEDHLHQQHLGVRPFKCNMCPKAFIRMDFLQCHYAKYHNFHRLSMMGLGDGGGIGGGGGGGGGGGGMNHPLDPIDRAVQRAALWNSGFLASGGGGGGGNTQGTHGRQDTSAAPGVPRLAVRKMEDLLDGPRRIAPGGGGGSVAPMGLYSRRTSHTTGTTIGSSSSDDNDEDDDEDELKMVVVLGDEDGDDEGTGAESNGQRKRKLTNGAHSVRSSAKKKKRATIGAEAAPLPVATVPAAPEAETGKHRCPVCERRFVHEPELMVHVRVHPDLPTYKCPLCELTFIGSDYLKAHLKKHVVGDGEDPNAPGAIDLKAPVETVSTATAPAPAPASSRTSITMSPAPSALIASKFPKIVSKVPSTGISLLKPLEERKPPDQQPQQQQQQQQQQQQHQPSQEYCTKTADGKFKCTVCERLFSHQQTVRIHFRNHTNEKPYKCAFCTESYIRSDYLERHLKVHFKDGVLPANAIASMAAAAAREAAAAVALSNGTGGGGQRLSLPSSPTPPPLVTAPAVKEDVKREVTPSTTPTPKPLIGRAGLAPENYHFAESNDGQYVCKICDKVFAQVASLRKHALAHNEEKPFYCEVCDRSFIRVDYLKEHFKSKRHLQLVSEGLIGLREVEEDDSTMDGGGSSRSRTAPPKRRSKPGDKRKATDALTGAGEATVDTIHPTLLAAANCGNSRCSSTSSTGSSGGSSSSSSSGSSSGGSISRSSSACEVAIIEHTPTKLVLNSSSNSNGAVQTPPSAGEQHPQQLQLQKATTTTPGSAGTTPEFHRSDYERTSDGRYKCNQCDKTFVTAVTLKMHIRLHTGEKPYKCDKCDKAFIRSDYLKTHEKTHRQQSFLSLLALTSKEPSTASEAGDDSDAGGEGARTPAPGNDHDHRHESVTTSVGGGRSSLLADNTADGREAIKREGRQGKGVEEGEVIDDAEEDAEEEEDDGEDGDPSEDSEEGEAEDEEEEEEDGAQVIKVMVKEASCESESENEDEEEEEEVDDEEDEEEEEEEGTGEEAEERASKKHFSASNSTIDLPDRESAATVSLLLQRNRAQPSAGREVAGAKEARAGFHSNRGSIVSGGESSNNGYDDHDDDDSASQTSDGQRLANGGASGGGSYWAQGGDPRPDKHSCPTCHKLFAWPKSLKIHMRTHTGEKPYRCDVCGKCFGRSDSLRGHKRTHSEEHQQQQQQQQRIMQCHLCDLCCTNGEQLVQHQLAAHGIQPLEC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00092941;
90% Identity
-
80% Identity
-