Basic Information

Insect: Anopheles albimanus
Gene Symbol: ZFY
Assembly: GCA_013758885.1
Location: NC:56195139-56200365[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.0063 0.3 11.0 0.0 2 23 237 258 236 258 0.97

2 22 0.51 24 5.0 0.3 1 23 264 291 264 291 0.90

3 22 0.0008 0.038 13.8 0.3 2 23 296 318 295 318 0.95

4 22 0.0046 0.22 11.4 0.9 1 23 327 349 327 349 0.98

5 22 5e-05 0.0024 17.6 1.9 1 23 357 379 357 379 0.98

6 22 1.5e-05 0.0007 19.3 1.3 1 23 385 407 385 407 0.97

7 22 4.7e-06 0.00022 20.8 3.0 1 23 413 435 413 435 0.98

8 22 2.4e-06 0.00012 21.7 1.0 1 23 484 507 484 507 0.96

9 22 0.0023 0.11 12.3 0.8 1 23 513 535 513 535 0.96

10 22 3.9e-06 0.00019 21.1 0.9 1 23 541 563 541 563 0.97

11 22 0.00056 0.026 14.3 2.4 1 23 569 592 569 592 0.96

12 22 0.019 0.91 9.5 0.1 2 23 1050 1071 1049 1071 0.97

13 22 7.1e-06 0.00034 20.3 1.9 1 23 1109 1132 1109 1132 0.97

14 22 0.00021 0.0099 15.7 0.6 2 23 1137 1158 1136 1158 0.97

15 22 7.8e-06 0.00037 20.1 0.7 1 23 1166 1188 1166 1188 0.99

16 22 0.017 0.83 9.6 4.9 1 23 1194 1217 1194 1217 0.97

17 22 0.0033 0.16 11.9 2.6 1 23 1226 1249 1226 1249 0.93

18 22 0.79 38 4.4 0.3 3 23 1278 1301 1276 1301 0.92

19 22 1.6e-05 0.00076 19.2 1.7 1 23 1305 1327 1305 1327 0.97

20 22 2.5e-05 0.0012 18.6 0.8 1 23 1333 1355 1333 1355 0.96

21 22 2.9e-07 1.4e-05 24.7 0.6 1 23 1361 1383 1361 1383 0.98

22 22 0.013 0.6 10.0 3.1 1 22 1389 1410 1389 1412 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.0063	0.3	11.0	0.0	2	23	237	258	236	258	0.97
2	22	0.51	24	5.0	0.3	1	23	264	291	264	291	0.90
3	22	0.0008	0.038	13.8	0.3	2	23	296	318	295	318	0.95
4	22	0.0046	0.22	11.4	0.9	1	23	327	349	327	349	0.98
5	22	5e-05	0.0024	17.6	1.9	1	23	357	379	357	379	0.98
6	22	1.5e-05	0.0007	19.3	1.3	1	23	385	407	385	407	0.97
7	22	4.7e-06	0.00022	20.8	3.0	1	23	413	435	413	435	0.98
8	22	2.4e-06	0.00012	21.7	1.0	1	23	484	507	484	507	0.96
9	22	0.0023	0.11	12.3	0.8	1	23	513	535	513	535	0.96
10	22	3.9e-06	0.00019	21.1	0.9	1	23	541	563	541	563	0.97
11	22	0.00056	0.026	14.3	2.4	1	23	569	592	569	592	0.96
12	22	0.019	0.91	9.5	0.1	2	23	1050	1071	1049	1071	0.97
13	22	7.1e-06	0.00034	20.3	1.9	1	23	1109	1132	1109	1132	0.97
14	22	0.00021	0.0099	15.7	0.6	2	23	1137	1158	1136	1158	0.97
15	22	7.8e-06	0.00037	20.1	0.7	1	23	1166	1188	1166	1188	0.99
16	22	0.017	0.83	9.6	4.9	1	23	1194	1217	1194	1217	0.97
17	22	0.0033	0.16	11.9	2.6	1	23	1226	1249	1226	1249	0.93
18	22	0.79	38	4.4	0.3	3	23	1278	1301	1276	1301	0.92
19	22	1.6e-05	0.00076	19.2	1.7	1	23	1305	1327	1305	1327	0.97
20	22	2.5e-05	0.0012	18.6	0.8	1	23	1333	1355	1333	1355	0.96
21	22	2.9e-07	1.4e-05	24.7	0.6	1	23	1361	1383	1361	1383	0.98
22	22	0.013	0.6	10.0	3.1	1	22	1389	1410	1389	1412	0.89

Sequence Information

Coding Sequence: ATGGAGTTTCTACGAAAAGAAGCAATATTAACGGACCTTCCCGGGTATCTGAACTCGGATAGTGCCGCTATGGGGTCTCAGAAATCGCTGTTGCAACGGTTTTGCCGGTTGTGCCTGCGTGAGTTTCCGTTTCTGCTACCTTTTAAAGCGACTCTGCATGGTACAACCCTCGCCGCCATGCTGGAGAGATTGCTTGGGGGATTCCAGGTGGCCCAAACGCACGATCTACCGAATCACATTTGCACCCGCTGTGTAACGAAACTAGATTTTGCGTACCACGTACAACTGGAGCTGGTCCGGAACGAGCACAGACTAAAACACTTCCTCAAGAATGGCCACCTAGTACAACAGctgtttgattttcaaaatattCATTCGGCGGTTCGGGAAAGCCACGCGGACAAGCTACTGGCATTACACGGTACCACGTTGCTCGGTGAAAGGGTTGTGGTATCTGAAGGAAAAGAAGTGCCAGGCATGCAGCTAGCAGAGATGGAAGCAGCAAAACTTTACAAACCAGAATTACCTTCCTGCACGACTCCATGCGAATGTCGCACAATACCCAAGGCCCCCACGCCACATTCTTATTCGCGATCTGCTGCAGAGCTACAGCTGCCGAAACGGACACTACGCAACCGACAAACCCTACGGGAGGCAATTAAGCGCGGCAGTACGGGTGGAATGAAAGTAATGCCTGTCGATATGACGAAATGCTACATTTGTGATACAGCGACGGCGAGTGAAGCCGATCTGCGGgatcacatcgcatcgcacgtgGATATGCTGCCTCACAGCTGCCCGGAGTGCAGTAAAGAGACCGAGGTAAAACCGATCACCTCGTTGGTGACCCTGCTGCGCCATTACCGGATGCACTCGTATCCCCTCAAATGCCCCAACTGTCCGCAGCGCTTTGTGCGATATGGCAATGTGTACGCACACGTCCGCTATCGGCACGAACTGTTTGATAATCCGGAGGGTTACACCTGCGAAGTCTGTGGACTGAAGATCAAGTATCGACCCACATTTATGTACCACATGCGAAACCATTACCACGAACAGATGGGCACGTTTAGATGCAGCTTTTGCGATCGCACCTTCGGAACTAAGGCGCGTCTCGAGCGCCACGAGAGATCCCACACGGGCGAACGACCGTTCGCTTGTCGCTTGTGCCCGAAAACGTTCGCACATCCTAGCCAGCTGACGGTGCACCGATCGCGGCACATAAACGAGCGTGGCCACCGATGCGATGAGTGTGGTAAAGCCTTTTACACTCGAACCTTGCtaaagcagcaccagcaatctCATAATCGGGAAGCGGGCGAATCACACCAGGATGCGGAAAAACGATCCTCACGGGCCGAGCCGCGTCCATGTACTTACCCCGGCTGTCAGCATGTGGGGGCCACTTATCAGGCGTACTACTTACACCGATTGCGCCACATAATGGCTCACGAGTGCGAGGAATGCGGTCGTCGGTTTGCACGCATGAGTGAGCTGCAGCGCCATGAAAGGATCTACCATACGACCGAGCATCCGTACCGGTGCGAACAGTGTGATAAGGTATTTCTGAGCAGACAAACCTATCGGGAACACATGGACGCGCACGCGAACATCCGGCGCTATGCGTGCGAAATGTGTGACAAGAAATTTGTGAGACGCCGGAATCTGTTAAATCACCAGAAGGCACATACGAATCAGCGGCCGTTTAAGTGTGAGCTATGTGAAAGCGCCTTCAAGTACAAAAGCGATTACAATCGGCATCAAAAGGACAGGCATAGGATGGAGCCACcggtggaagaggaagaagacgaggaACAGCGGGACGGAACATCCGGCGTGAGCAACATCGTTCTCATAGCGGACCACTCGATGGATAAAGGGGAAATTCTGAGGAGGGCACTCGAACAGCAAATTTTAGTGGAAGGGGATGTGCACGGTCAGGTATCCTACATCGGAGAAGAGGACGTTACAAAGTACGAAGAGATTGAAACCGTCGAGGAGTCGATCGTATTTGAACAACCGGGCGGGGCGCTGGAAATAGAGGATGTGCCAAAGCGGGAGTATATCATTGAATACATCCAGCAGAACTTATCCGTCTGGACGCACCGTATATGTTTTGCGACTCGTCTAGCCGTCGCTGAAGCTGTCATAGTTGCAAGAAGCTTGGTCAAAAGTGCGCCTCAAAATAAATTTCTGAACCGTGGATCGGCGGTTCAAAAAATGGGTTTGATAAAACAGGAAGTCGTTGAGGAAAGTGTAATTGAGGGCGTAGGAGCAGTGCGTGCCACCAGCGTCGACGATTTCTGCCGAATTTGTTTGCTGAAGCGGCCCAAGCTGATATCGTTGATGGACCGGGTGGATGGCGTGATGATACCGGAAATGCTGTACAAGCTGTGCGGAACGCAGATCGAAGTAATCGATCGGTATCCCCGTCGTATCTGCGAACACTGTCTCGACACGCTAGACACGGCCTATAGCTTCTTGAGCCAGTTCCGGCAGCAAGATGAGCGGTTGCGCAGTTTCTACTGGAATGGATCGGTGGTGGCCCAGTTGGAAACCTACCAACCCGAAGGTGAACTCGATTTCACCAAGCGCCTGCAAGAGCTATTGTCACGCAACAATAGTATCACGGCAGCGAGAAGCGCATCAAACGCGAAGGAGTACTCTTCAAAGGGGACCGAAACAGATCCAATTGTACCGGTGGAAACGACGGATGTGGCTACCAACACCGAAGATCGTGTAAATGTTGGGCAACTGCTACTCCCGAAACAAGAGCAAGATGATCAGACTGCATGGGAAGTGTGCGAAGGAGTTGAATATGACGAGATCGAGATTGAAGAGGATTCCGCCCATGAAGTCATTGACGAATCGCAAACGGCCGAGCAAGGCGATTCGGGCGACGCGTTGGTATCTATGGAGATCGATTTGTTGCCCGCTTCGAAAGGTCAGCATGACGGCGTGGAAAAGGAGGAGCACAATGAGCAACTTCAATCTTCGAGCAGGCATCAGCGAGTTGCTGTAGAAAGCATAGACGATCCGAGAGGAATAACCTATGAGGTTGAAATGATCAGCGACTCTGAAAGTCTCCACACTATCGAGGCTGAGCAGGGTCAAGATGTGCACGAAGAGACCATAGACCATCGGGTAGTGTGCCATATTTGCGAGTTCATGGGaacagacgatgatgatctgcAGGAGCACCTGAAAGTGCATGCTGATTTGTTGCCCTACACATGCCAGCAATGCGTAAAGGCGGGCAGTAATTTGGAACCGCTGACGACACTGGAGACTCTGTGTAATCATCTGCTGTGGCACAGCCGGGGCTACGAGTGCAAGGAATGTGGCAAACGGTTTACCTCCGAGAAGGCATATACCAAGCATCGCGACACGCAGCACAGCGGCGATCTAGTTTGCGAGGAATGTGGAAAGCAGTTTCGGATCCGGAAAAGCTGGAGCAATCACATGCAGCGCCATGCGGCCGTACGGCGCCAGAAGTACAAGTGCGAACTGTGCCAGAAAACGTTCGCCAATCGGCCCCGTTTGGTGCGCCATTTGCGCGTCCATACGGGTGAAAAACCGTACTCATGTATGCAATGCGATCGGCGATTTATTGACCATCATCAGAGGCAGCGACATGTCCAAAGAATTCACGAATCGGAGGAAACGGGTAGCAGCTTCCAGTGTGAGTGTTGTGGCACCAGCTTCAAAACTTCTCGACAACTAGAGAGCCACAGTGTCACCGAACATATGAGCCCGGAGGAGCAACAGGAGTATCGCGAGCTGCGCAAACAGCGGTACATGAATCGGTTGGACCAATTGACAGAGGACCATTGCCCGTTCCCTGGCTGTGATTACAAGGCTAGAACTTACGGTGCACTGTACGTGCACAAACGTGCGAAGcacttcctgctgcaccaGTGTGAGGTGTGCGGTAAAAATTTCCCCTTCCAGAACCAACTGAACACACATATGACCCTGCATACGGGTGAGAAACCGTACGAGTGCGAAGACTGTGGCCGCAGCTTCCGGCGACTTTTCAGCTATCGGGAGCATGTAGAGCAACATCGGTCCGATAAAACTTACCCCTGCTCGCTTTGTGATAAGACCTTCCGGAGACCACGATATCTGCAGGCACACCTCCTGACGCATTCCTCCGAGAAGCCGTTTAGCTGCGAAGAATGTCCCAATCGGTACAAGACGCGGGGCGAGCTCAAGAAACACTGCCGAGCGAAGCATCAGGTCGAGGAGCTTGTTCCATTGCAAGGTATCCAAGTGCGGGAGGAGCTAATCGAAGAAGAGTACGTCGATGGATTTGAATAG
Protein Sequence: MEFLRKEAILTDLPGYLNSDSAAMGSQKSLLQRFCRLCLREFPFLLPFKATLHGTTLAAMLERLLGGFQVAQTHDLPNHICTRCVTKLDFAYHVQLELVRNEHRLKHFLKNGHLVQQLFDFQNIHSAVRESHADKLLALHGTTLLGERVVVSEGKEVPGMQLAEMEAAKLYKPELPSCTTPCECRTIPKAPTPHSYSRSAAELQLPKRTLRNRQTLREAIKRGSTGGMKVMPVDMTKCYICDTATASEADLRDHIASHVDMLPHSCPECSKETEVKPITSLVTLLRHYRMHSYPLKCPNCPQRFVRYGNVYAHVRYRHELFDNPEGYTCEVCGLKIKYRPTFMYHMRNHYHEQMGTFRCSFCDRTFGTKARLERHERSHTGERPFACRLCPKTFAHPSQLTVHRSRHINERGHRCDECGKAFYTRTLLKQHQQSHNREAGESHQDAEKRSSRAEPRPCTYPGCQHVGATYQAYYLHRLRHIMAHECEECGRRFARMSELQRHERIYHTTEHPYRCEQCDKVFLSRQTYREHMDAHANIRRYACEMCDKKFVRRRNLLNHQKAHTNQRPFKCELCESAFKYKSDYNRHQKDRHRMEPPVEEEEDEEQRDGTSGVSNIVLIADHSMDKGEILRRALEQQILVEGDVHGQVSYIGEEDVTKYEEIETVEESIVFEQPGGALEIEDVPKREYIIEYIQQNLSVWTHRICFATRLAVAEAVIVARSLVKSAPQNKFLNRGSAVQKMGLIKQEVVEESVIEGVGAVRATSVDDFCRICLLKRPKLISLMDRVDGVMIPEMLYKLCGTQIEVIDRYPRRICEHCLDTLDTAYSFLSQFRQQDERLRSFYWNGSVVAQLETYQPEGELDFTKRLQELLSRNNSITAARSASNAKEYSSKGTETDPIVPVETTDVATNTEDRVNVGQLLLPKQEQDDQTAWEVCEGVEYDEIEIEEDSAHEVIDESQTAEQGDSGDALVSMEIDLLPASKGQHDGVEKEEHNEQLQSSSRHQRVAVESIDDPRGITYEVEMISDSESLHTIEAEQGQDVHEETIDHRVVCHICEFMGTDDDDLQEHLKVHADLLPYTCQQCVKAGSNLEPLTTLETLCNHLLWHSRGYECKECGKRFTSEKAYTKHRDTQHSGDLVCEECGKQFRIRKSWSNHMQRHAAVRRQKYKCELCQKTFANRPRLVRHLRVHTGEKPYSCMQCDRRFIDHHQRQRHVQRIHESEETGSSFQCECCGTSFKTSRQLESHSVTEHMSPEEQQEYRELRKQRYMNRLDQLTEDHCPFPGCDYKARTYGALYVHKRAKHFLLHQCEVCGKNFPFQNQLNTHMTLHTGEKPYECEDCGRSFRRLFSYREHVEQHRSDKTYPCSLCDKTFRRPRYLQAHLLTHSSEKPFSCEECPNRYKTRGELKKHCRAKHQVEELVPLQGIQVREELIEEEYVDGFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -