Basic Information

Insect: Anomoia purmunda
Gene Symbol: topi
Assembly: GCA_951828415.1
Location: OX639993.1:147072986-147075760[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 5e-05 0.011 18.0 2.6 1 23 295 317 295 317 0.97

2 10 0.46 99 5.5 1.2 2 23 352 373 351 373 0.91

3 10 0.055 12 8.4 0.1 2 19 435 452 434 454 0.94

4 10 0.074 16 8.0 2.2 1 22 503 524 503 527 0.90

5 10 1.2 2.6e+02 4.2 0.3 2 20 542 560 541 564 0.78

6 10 1.6e-06 0.00034 22.7 2.3 1 23 584 606 584 606 0.95

7 10 0.0037 0.79 12.1 1.1 1 23 612 637 612 637 0.95

8 10 0.55 1.2e+02 5.3 1.7 1 23 643 665 643 665 0.88

9 10 4.7e-08 1e-05 27.5 0.4 1 23 671 693 671 693 0.99

10 10 0.053 11 8.5 1.4 3 23 701 722 699 722 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	5e-05	0.011	18.0	2.6	1	23	295	317	295	317	0.97
2	10	0.46	99	5.5	1.2	2	23	352	373	351	373	0.91
3	10	0.055	12	8.4	0.1	2	19	435	452	434	454	0.94
4	10	0.074	16	8.0	2.2	1	22	503	524	503	527	0.90
5	10	1.2	2.6e+02	4.2	0.3	2	20	542	560	541	564	0.78
6	10	1.6e-06	0.00034	22.7	2.3	1	23	584	606	584	606	0.95
7	10	0.0037	0.79	12.1	1.1	1	23	612	637	612	637	0.95
8	10	0.55	1.2e+02	5.3	1.7	1	23	643	665	643	665	0.88
9	10	4.7e-08	1e-05	27.5	0.4	1	23	671	693	671	693	0.99
10	10	0.053	11	8.5	1.4	3	23	701	722	699	722	0.95

Sequence Information

Coding Sequence: ATGATGAATCCAACTGAGGAAGAATTCGCTAATTCCGATGCATGGCTATCAGAGCAACTATTCGCTCAgctaaaagaatttaattcagaCTTTAGGGATAAGTCGGTAACGGATACATCGGCAGCATTTGTATTTCCGTCTGGAAGCCTCAATTGCTTATCTGAAGATGAACCGCAAGATTTAACTAAAACTAGgatggaaaattttgaatcagTCTTTAAGCTTTCTACACCCACGAATATGACTTCTTTCGATATGAATGACGTACTCGATTTAAGCAATATTGCTGGTAGAGGCCCCGATGCAACTCTATTGGATTTCGTTGGAACAGTTCCACTGGCACCATTTGGGCCACCCGTTGTGGAAGCTCCTATAATGGCAACTGAACCGGTAAAGCAAGAAATAGCACATTTTAATGCCACAGAAGAGGAGCTGAAACTTCTGAAATTTCTTGAATCGCAACCACAAGTCAATCAATTTGattcaaaaatctgtatgcCGCCTGATTTGAGCTCGACAGCATATCGCATCGTGAAATGCTCAAATTGTAACTGTCTCTTTGATATAATATCATTTCAATCTCATGTTTGTGATTACGATGAACAACACAATCTCATTATTCCTCCGACAATCACATCAACACCCATTAGCAAACCAATAAAGGAAGAGCCGATATTACCAATAGAGCCGGCATGCATTCGGTTGTTGCGCGAAAATCAAATTCGAATTCGTCGATTTCTTAAGGATGAACTTAAATATGACGTCAATGCATTAATTAACAACAATATGAGTAATTCGAATAATACTATTGGCAGTAGTACTTCCAACATATCTACCGGTTCTAGTTCATCAgctaataattcaaaaaaacaagATGGACCCCATGAGTGCACCTTGTGTGAGCGAAAATTTGTGCATGCTTCAGGTTTATTGCGCCATATGGAGAAACATGCAATGGATTTAATTCCAACGCCTGGTGCCACTACTGGTGGAAAGACAACCACAACACAAGGTAGTTCACTGCAAAGCGTTAATGGGCTTCGTGTGGTCATTAAGTGTACTTTGTGTGGACGTATTTTCTTTGAACCAAACGCTGGATTCAAGCATTTATGTTCTCATTTTCCTGGAAGCATCCAGGACGAAAAAGAATTCGATAATTGCGCTGAAATACCGTATGAGTCGTATGTGGATGATGCAACGAATTTTTTGAGAATCGAGGCGAAAAGCTGCTCTGGTGCATTAACTATTCATGAAGATAAACCTCCAGTGTATCTTAAAATGGTTATACTCAGTTGCATTTTACAATGCGAGTTTTGCGATTTTGTGTTCTCAGAGGTTTCATATCTCTTCGTTCATTCTGCTTGCCATTTACCAGAACGGCGCTTTGAATGTTTCTCATGCGACATTCATATGCGTACGTCCAAAGAGATTTGCGCGCATTGGCAAGCCGAGTGTGTATTCATGCGAGAAAATTTAAAGGTTCATCAAGCTACCACTCAACGCTATTTCGTTTGTAATGTTTGTGAGAATAAGTTTCAGTCCCTTGACCAATTGCATGAGCATCGATACACATCATATCACTTTTTCCCGCGCTTGAATAAATGTATCGGTGCATTACAATTACCCTGTGAGTATTGTGATGTAGTTTTCGAATATGCACAAGAGTGTGTGGCTCATTATGAAGATAAGCATTATAAAAAGTATAAGCGTGACAAGGATGGGACGGGTTCTTCAAGTAAAACACGTCAGTACTTGTGTGATATGTGCGGGAAGTCCTATACACAATCAAGTCACTTATGGCAGCATTTGCGTTTTCATCAAGGAGTAAAACCATTTGCATGCAAAGAACCCGGCTGTACCCGCAAATTTACCATTCGTCCTGACTTAAATGATCATATCCGCAAATGCCATACTGGTGAGCGCCCATATCATTGTTTGGTGTGTGGCAAACGCTTCCTAACCGGTTCAGTTTTCTATCAACACCGTCTCATACATCGTGGTGAGCGGCGCTATGAATGCGAAGAGTGTGGTAAAAGGTTTTATCGTGCGGATGCACTTAAAAATCATCAACGTATTCACACTGGCGAGAAACCATttggttgtttgttttgtaCGAAAAACTTTCGTCAGCGCGGTGACCGCGACAAACATATCCGAGCTCGACATTCTCACTTAGATGCCAATGCCCGTTTGATgatgcaaatgcaaaaattacaactcgaagcagcagcagcagctgctgCCTCACAAGTTTCAGTCCAGCAGCCGCAAGCAACCAATGCAGATATAATAAGCGGAATACCTACTGTAGCACCACCTCTTTTGAATATGCCATCTGTTAGCAATGATATAATTGAAGGGCTAGAACCTCCATTAGATCCCAACGAAGTTGTCATGATTGGAAATGTGGCCTTTCCGAAAAGTATGTTTGAATCTATAATACCAGATATAGACGAAGAATCTGCACTAAGGGCTATGGAACAGTTGCAATAg
Protein Sequence: MMNPTEEEFANSDAWLSEQLFAQLKEFNSDFRDKSVTDTSAAFVFPSGSLNCLSEDEPQDLTKTRMENFESVFKLSTPTNMTSFDMNDVLDLSNIAGRGPDATLLDFVGTVPLAPFGPPVVEAPIMATEPVKQEIAHFNATEEELKLLKFLESQPQVNQFDSKICMPPDLSSTAYRIVKCSNCNCLFDIISFQSHVCDYDEQHNLIIPPTITSTPISKPIKEEPILPIEPACIRLLRENQIRIRRFLKDELKYDVNALINNNMSNSNNTIGSSTSNISTGSSSSANNSKKQDGPHECTLCERKFVHASGLLRHMEKHAMDLIPTPGATTGGKTTTTQGSSLQSVNGLRVVIKCTLCGRIFFEPNAGFKHLCSHFPGSIQDEKEFDNCAEIPYESYVDDATNFLRIEAKSCSGALTIHEDKPPVYLKMVILSCILQCEFCDFVFSEVSYLFVHSACHLPERRFECFSCDIHMRTSKEICAHWQAECVFMRENLKVHQATTQRYFVCNVCENKFQSLDQLHEHRYTSYHFFPRLNKCIGALQLPCEYCDVVFEYAQECVAHYEDKHYKKYKRDKDGTGSSSKTRQYLCDMCGKSYTQSSHLWQHLRFHQGVKPFACKEPGCTRKFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPFGCLFCTKNFRQRGDRDKHIRARHSHLDANARLMMQMQKLQLEAAAAAAASQVSVQQPQATNADIISGIPTVAPPLLNMPSVSNDIIEGLEPPLDPNEVVMIGNVAFPKSMFESIIPDIDEESALRAMEQLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00081676;
90% Identity: -
80% Identity: -