Basic Information

Insect: Anisolabis maritima
Gene Symbol: ZNF646
Assembly: GCA_010014785.1
Location: JAAAKE010000941.1:2965-18562[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0074 2.4 10.6 0.3 2 23 528 550 527 550 0.92

2 16 7.1e-05 0.024 16.9 0.4 2 23 654 675 653 675 0.95

3 16 0.0036 1.2 11.6 2.2 3 23 682 702 680 702 0.96

4 16 3.6e-06 0.0012 21.0 1.5 1 23 708 730 708 730 0.97

5 16 2.9e-06 0.00097 21.3 1.1 1 23 737 759 737 759 0.98

6 16 9.7e-06 0.0032 19.6 2.6 1 23 765 787 765 787 0.95

7 16 0.00044 0.14 14.4 4.4 1 23 796 818 796 818 0.98

8 16 0.0028 0.92 11.9 4.3 1 23 824 846 824 846 0.97

9 16 1.7e-05 0.0055 18.9 3.5 1 23 852 874 852 874 0.98

10 16 8.9e-05 0.029 16.6 1.0 2 23 880 901 879 901 0.96

11 16 8.9e-05 0.03 16.6 0.4 1 23 922 944 922 944 0.98

12 16 0.0004 0.13 14.6 0.1 1 23 950 972 950 972 0.97

13 16 0.00014 0.047 16.0 1.5 1 23 978 1000 978 1000 0.98

14 16 0.00024 0.079 15.3 0.5 1 23 1006 1028 1006 1028 0.97

15 16 1.7e-08 5.6e-06 28.3 5.0 1 23 1034 1056 1034 1056 0.99

16 16 9.2e-06 0.003 19.7 1.1 1 23 1062 1084 1062 1084 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0074	2.4	10.6	0.3	2	23	528	550	527	550	0.92
2	16	7.1e-05	0.024	16.9	0.4	2	23	654	675	653	675	0.95
3	16	0.0036	1.2	11.6	2.2	3	23	682	702	680	702	0.96
4	16	3.6e-06	0.0012	21.0	1.5	1	23	708	730	708	730	0.97
5	16	2.9e-06	0.00097	21.3	1.1	1	23	737	759	737	759	0.98
6	16	9.7e-06	0.0032	19.6	2.6	1	23	765	787	765	787	0.95
7	16	0.00044	0.14	14.4	4.4	1	23	796	818	796	818	0.98
8	16	0.0028	0.92	11.9	4.3	1	23	824	846	824	846	0.97
9	16	1.7e-05	0.0055	18.9	3.5	1	23	852	874	852	874	0.98
10	16	8.9e-05	0.029	16.6	1.0	2	23	880	901	879	901	0.96
11	16	8.9e-05	0.03	16.6	0.4	1	23	922	944	922	944	0.98
12	16	0.0004	0.13	14.6	0.1	1	23	950	972	950	972	0.97
13	16	0.00014	0.047	16.0	1.5	1	23	978	1000	978	1000	0.98
14	16	0.00024	0.079	15.3	0.5	1	23	1006	1028	1006	1028	0.97
15	16	1.7e-08	5.6e-06	28.3	5.0	1	23	1034	1056	1034	1056	0.99
16	16	9.2e-06	0.003	19.7	1.1	1	23	1062	1084	1062	1084	0.98

Sequence Information

Coding Sequence: ATGTCGCTGCAGCAGCATCAACAGAAACGTTTAAAATGTGCAGCAACTCACTGTACGAATCCAACACAAATGGTCCATGCCTTCCCCAAAGATCCCAagagatttgtcATCTGGGCAGACCGGGCAGGTATTATAGGAAAcctttcaaataaagtttttgtccAAGAATATGGATTATGTAGCAACCATTTCCCTGATGTATACTTTCTACCACCTGATTATAAAACATTGGTCGATTATGCAGTCccagaaattttccaaaatgaaaatgGTGacgttgttttatataaaagagatgaaTACCAAGAAAATTTGGTAGAACAGCAGGCTGAAATCATAATTGAAGACCACACTAATGTGGGGGGAGATGATGAGGAtgaagtaatttatattaaaaaattacataatacatatgaatCATCCTATGTACCTGATATTACAAAcattttagaattgaattatGGATTGAATGCTAACGAGGTGAATATAGTACAAGAAAATATCGACGGAGATAATATAACTCAAGAAAATAATGAAGGATTATCTAATGAAAATTGGAATGGAATTAATCAAGAACGTTATTCACTTATTTCTGAATTATGCCGAGTGTGTGCAAAGCCCGGGATCAATATGATTTCTGTCTTCGAGGCcaaaggaaagaaattaaatcttttagagaaaatacaCTCGGTTCTACCAATTCtggttACTGAAGAGGATATTCTCCCTTCCCATTTATGCGGTTCTTGCATAACACAATTAGATATCAGTCACCGGCTTTACAATAGATGTCTTGAAGCTGATGCtaaactaaaaacaattttaggataTGTGCCACCACCTCAAAGAGAAGACTTTTCCGATAATTTCACCTTTGAGCACGTCTCTGATGACAATTATACAATTCATATCAAAGAAGAGCCACTCGAGGAAGAGATGCTCGACAACCCACTCATTTCCAATGACAATGAAATTGATTCTGAGATCATCGTTATCGAAAACCCAAATTCTATGATTGACGatgaaattgaattcatttcaactccgccaccaccaccaccaccaccaccgcccCCGCCCCCACCACCACCCCCTCCACCCACTCAGAACGAAATTGctgaatttgagaaaaagacaaaagaaaaatcatccCCAACTATCAAGAAATCGGCAACCACTCACTTGCCTGatgttgttaaagaaaaattagaaaagatcaATaaaaagaaaaatccaaatgcGAAAGTCGttgttgttaaattaaaaaatattaaaaatttacctccAGAAGCTCAAATTAAAAAGGCTTTGAAATTAGTGAATAAAGCCAAACAAgatcctgaaaaagaaaaagaagagagacaagcCTTTAAAGCTGATGGATTCTTGTCTGGTATTCAAAATGAATTGTATGCTGAAAATGAAAGAATCGACTCGACAATGGATAGTCCAGgtccttcttcttctacttctttaCTGAAAAACCCACGGGAATATGAAAAGGAAGCTTGCGAAAAAATTATGGCTTGTGATACAGAAGGAGTTCCTCATGTCATAACTCGATTCAAGGAAGCACTTTTTTTATGCATGTTTTGCAATAAAACAGTAGCAGGCAAAGATAATCTAGTCCAACATCAAAAAGATATACATCCTGATCGGGTGACAACTTGCGAAGTATGTCATACCGTTGTCTATGGTGGTCAAGCCCAACAACTAGCACACGCTCAGACACACATGCTTATGAATTCGTCAGCAATTTCAACAGGATCGGTCACCCAGCCAGTCCCATATATCCAAATCTCGGCTGGAGAAGCCAATTTGGAAAATAGCGACATAATTGCGACTACACCCACACAATTAGTCGCGACTAGTCAAGCTAAAAACGCTTCAGTACCACGAGGTCGAAAAATGCGACGTGAAAACAATTCTAGCACTGGCAAAAAGAAACGTCGAGGGTGGCGTTGCCGAATTTGTGATGAAATTTTCCCCACTAAAGAAGAGTTGAAAAAACACAAGGACTCGCACCCTCCTCGGGTTTGGGCTTGCAATTACTGCCCcaaacaatttaataacaaatgcaCGCGCGAACAACACGAACGCATTCATACTAACGTCAAGCCCTTTATTTGCGAATATTGTGGCAAGAGTTTCAGGATGAATCAAATGTTGAGAAATCATCTCTATACTCACGATGTGCTAGAGAAGAAATATGAGTGCAAACAATGCAATAAGAAATTTAGTTCCAAGAGTGGCTGGAATGCACATCAAATTTCACATTCAAGTGAAGCCAAATTCCTCTGTGATCTATGTGGAAAAAGTTTTCGACATGAGGGAAATTTACGCTTACATAAACGAAATCATCAAGATCCAATGTCATTATATAAACATACGTGTGAAGTATGTGGCAAATCATATCAAACCAAaTTCCGACTTCGAGAACATTTCCGAACTCATACAAATGAAAGACCCTTTGAATGCACCTCATGTGATAAGAAATTCCacaaattcaatcaattaaaacagCATCAGGCGATTCATATTAATGCAAGAAAACATAAATGTCATATTTGCGGTAAGGGCTTTAACCGGAGAGGCAACATGGTCATCCATACACAAAGACATCTCAAGAATAAGCTCGTCTGCAAAATCTGTGGGCACATGTTCACCTCCTTAAAGGAGTTGCTTGCTCATAGAACTTCACACCCTAAAGGAGAGATCGATGCAGTTCTCAAGGAATTGAGTGAAAAGggcaatgaaaatgtatttgaatGCCTTGAGTGTGGAAAGTATCTTTCAAGTAAAGTGTCATTCAAGGCACACATGATGTTGCATAGTGGCGAACGTCCATTCGCCTGTACTCTATGTGAAAAAAGTTTTGCTGTGAAGGCAGTCCTTGATAAGCACATGTTAAGTCACACGGGAGAGAAACCGTTCACATGCAAATTCTGTTCGGAAGGATTTACCACAAGAACGAGTTTAGTGGTCCATGAACGAAGACACACCGGAgaaaaaccttataaatgtTCGCAGTGTGTTATGGCATTCCGTTCACGAATGAATCTTACACAGCATGAAATCGTTCATTCTGATAAACGGCCTTTCAAGTGCGACCATTGTGATAAAACTTTTCGGAGAAGAGATGCTCTTAAGACGCATATGAGAACACATACTGGTGAACGACCATATGCCTGTGGGATCTGCGGAAGAGCTTTCAGACAGAAGGGCGATTGTAACAAGCATATTAGGACGCATTATAAGGGACAATGTCCTATATCATTCGAGGTCTTGAAACCAGACATCTTCGCAGAGAAGGCCTTGGTGTCTTCTAAGATGTTCAAATCCAGACGTCCACCATCAAAAGAGCCAAATATGATATGGAGGCCATCCCGGGATGATAATTATGGAAATCCTGGATTGAGGACATTCTCGTCTGGTCTCACGGGACTCCACCCCACCGTGGATCAAGCTCTCAATGCTTTCCTTTGA
Protein Sequence: MSLQQHQQKRLKCAATHCTNPTQMVHAFPKDPKRFVIWADRAGIIGNLSNKVFVQEYGLCSNHFPDVYFLPPDYKTLVDYAVPEIFQNENGDVVLYKRDEYQENLVEQQAEIIIEDHTNVGGDDEDEVIYIKKLHNTYESSYVPDITNILELNYGLNANEVNIVQENIDGDNITQENNEGLSNENWNGINQERYSLISELCRVCAKPGINMISVFEAKGKKLNLLEKIHSVLPILVTEEDILPSHLCGSCITQLDISHRLYNRCLEADAKLKTILGYVPPPQREDFSDNFTFEHVSDDNYTIHIKEEPLEEEMLDNPLISNDNEIDSEIIVIENPNSMIDDEIEFISTPPPPPPPPPPPPPPPPPPPTQNEIAEFEKKTKEKSSPTIKKSATTHLPDVVKEKLEKINKKKNPNAKVVVVKLKNIKNLPPEAQIKKALKLVNKAKQDPEKEKEERQAFKADGFLSGIQNELYAENERIDSTMDSPGPSSSTSLLKNPREYEKEACEKIMACDTEGVPHVITRFKEALFLCMFCNKTVAGKDNLVQHQKDIHPDRVTTCEVCHTVVYGGQAQQLAHAQTHMLMNSSAISTGSVTQPVPYIQISAGEANLENSDIIATTPTQLVATSQAKNASVPRGRKMRRENNSSTGKKKRRGWRCRICDEIFPTKEELKKHKDSHPPRVWACNYCPKQFNNKCTREQHERIHTNVKPFICEYCGKSFRMNQMLRNHLYTHDVLEKKYECKQCNKKFSSKSGWNAHQISHSSEAKFLCDLCGKSFRHEGNLRLHKRNHQDPMSLYKHTCEVCGKSYQTKFRLREHFRTHTNERPFECTSCDKKFHKFNQLKQHQAIHINARKHKCHICGKGFNRRGNMVIHTQRHLKNKLVCKICGHMFTSLKELLAHRTSHPKGEIDAVLKELSEKGNENVFECLECGKYLSSKVSFKAHMMLHSGERPFACTLCEKSFAVKAVLDKHMLSHTGEKPFTCKFCSEGFTTRTSLVVHERRHTGEKPYKCSQCVMAFRSRMNLTQHEIVHSDKRPFKCDHCDKTFRRRDALKTHMRTHTGERPYACGICGRAFRQKGDCNKHIRTHYKGQCPISFEVLKPDIFAEKALVSSKMFKSRRPPSKEPNMIWRPSRDDNYGNPGLRTFSSGLTGLHPTVDQALNAFL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -