Apra010916.1
Basic Information
- Insect
- Andrena praecox
- Gene Symbol
- -
- Assembly
- GCA_963932275.1
- Location
- OZ010728.1:12002235-12004569[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 8.2e-05 0.012 17.1 2.4 1 23 294 316 294 316 0.97 2 12 0.00017 0.025 16.0 2.5 1 23 320 342 320 342 0.98 3 12 0.0014 0.21 13.2 4.0 3 23 349 369 347 369 0.96 4 12 0.0003 0.044 15.3 2.5 1 23 421 443 421 443 0.98 5 12 0.0009 0.13 13.8 1.4 1 23 448 470 448 470 0.97 6 12 0.00025 0.036 15.6 1.5 1 23 519 541 519 541 0.98 7 12 0.00033 0.047 15.2 0.9 2 23 549 570 548 570 0.97 8 12 1.1e-06 0.00016 22.9 2.1 1 23 580 602 580 602 0.96 9 12 0.00025 0.037 15.5 1.6 1 23 608 630 608 630 0.97 10 12 0.00018 0.026 16.0 0.7 1 23 636 658 636 658 0.98 11 12 5.4e-06 0.00078 20.8 2.0 1 23 664 686 664 686 0.96 12 12 9.6e-05 0.014 16.9 0.3 1 22 692 713 692 713 0.96
Sequence Information
- Coding Sequence
- ATGACAGGATACTTTGATCTGCCTCTTAATATGGAAAGAATATGCAGAATTTGCCTTACAGAGGGTACAAATTTATCTCCTATTTTTTGTACCGATCAAGAAGTAAGCGACTTTTCGAGTCTTCCACAAAAAATACAAGTATGCGGATCAATAGAAATTCACGAACAAGACGGATTACCCTCATTAATTTGTGATCTTTGCATTTATAAAGCGAGCGTTGCTCATGAATTTAGGCAACAGTGTCAACACTCTGACGCCAAATTACGACTGTACTATAACAAGCCAGCGAAGGTTACGATCGTGGATACGTGCACGCAGACAGAATCAGAAACGAGGGCAGCGTTACCAAAAAAGCCGgtcggcgacgacgacgacgactattTTGTAAAAGAGGAGATGCGAGGGACGGCGAACTCTCAAGAATTCGTGCCGAGCAATTCGTATCCCAGGGACGAGCCTAGCTTGGGCGCCGGTCAGATCGACATGCAGAGCGAGAAGCTCTTCATATGCTCCATTGGGTTCGAGGGACCCAAGGAGATCGAGAAAGAGCCTTGCGCCGTAGAGAATAACATTCGTCAGACTTGCCTTGCGCGAGGAAGCGGCGGCGATATCTCCGAGACTACAGAGACGCCGATTAAGCCCGAAGACAGTCGAGCTATCGATCGAAATGCGGACGATAacgagaagaaagaagaagaggagtaTGTCGGCGAAACCGTATTAGCCGAGACCATCGCCGAGGAGGAAGAGCGAGTCCCGCAGAAGCGCACGTCCGCTAGGAAACTGAAGTCGCTGCCTCAGAAAACTTACAGCGAAGATGAGATCGACGATAATTATTACGATCCTAGTAGCGATAGTCAAGATTCCGGGGAATCGAAGTTTAAATGTAAGATATGCTTGAAACGTTACAGTACGCAGAAAGGCTTGAAGAAGCATTCGCTCGTTCACGAGAAGAAGTATAAATGCGACGTCTGCCTGAAGATGTTTTACAAACAAGAGAACATGAAGAATCATAAAAAGATACACTCGTCCAAGCCCCTCGCTTGTAAGTTGTGCCACGCGTGCTTCTCCAAGCCTCAGAGCTTCGCGCGCCATTTGAAGTCCCACACGGAGAAGCTGAACAATATGATCAAGCAGATTAACACGGACGATCAGAAGGACAGCAAGGAGGTGAGGAAGGAGGCGAAACCGGACGAAGATACGGACGACGAGAGCGGCACCGTGAACGAAGTGGACGAATTCGAGAATGCACCTGAATTGTACAAATGCGATATTTGTAGTCAGTATTGTTCTTCCTTGAAGAATCTGAAGAGACACGCTCTCGTGCACGGCGATAAGAAATATTCCTGCACCGTATGCAAGAAATGGTTCTTCAGACCGGACACATTAAAGAAACACGCCGAGAAGCATGGCCACGGATTGTTAGATAATTTAGTAGAGGACAACAAGTTCTTCGACTCCGACGACGACCCGTTCCCGAATACCGTCACTAATACCTCGCAGGAGAGCGAAAGCGTTAAGAAGGAAGAGAGCGACGAGGACGGCTCCGGCGAATACAAATGTCAGCATTGTGATAAAATCATGGCTACGAAGAAGGGCCTCAGACGTCACGTAGCGATGCATAAGCCTAAAGCTGAACCGGTCACATGCGAGATTTGCCGGAAAGTCTGCGCTAGTCAAGCCCGCCTCGTTCTTCATCAAAGGACACACAAGCCGAAGGAGAAGGTACCTAGGGAATACCTGTGTCATATTTGTAGTAAAGTGTATCCGAGTAATTCCTCCCTCACATATCACATGAGAACTCACACCGGCGTCAAGCCGCACGTGTGTAAGACTTGCAACAGCGGGTTCACGACGACGACCAGTCTGGCGAACCACATTAGGATCCACACGGGCGACAAGCCGTTCGTCTGCCACGTGTGTAGCGCAGCGTTCGCCGTAAGCTCGGCTTTCAGGCGGCACTTGACTCGGCATACGGGCGAAGCGAATTATCTTTGTAAGACTTGCGGCAAAGCGTTCAAACGACTTAGTACTTTAAAAGAACACACTTACACTCATTCCGGCGAGAAGCCGTATGTGTGCAAAACGTGTGGAGCTGCGTATAGCCACAGCGGAAGTTTGTTCGCGCATCAGAAGCGTTGTAGAGCTCAGTACGGCGAAATGGTCGTGGATGACCATCACCATCAGGTGGCTCACCACATTCATGTGAATAATGTACAGTCTGCAGTGCGGTCACTTGCTGTGATAGGACAAATGTTTTAA
- Protein Sequence
- MTGYFDLPLNMERICRICLTEGTNLSPIFCTDQEVSDFSSLPQKIQVCGSIEIHEQDGLPSLICDLCIYKASVAHEFRQQCQHSDAKLRLYYNKPAKVTIVDTCTQTESETRAALPKKPVGDDDDDYFVKEEMRGTANSQEFVPSNSYPRDEPSLGAGQIDMQSEKLFICSIGFEGPKEIEKEPCAVENNIRQTCLARGSGGDISETTETPIKPEDSRAIDRNADDNEKKEEEEYVGETVLAETIAEEEERVPQKRTSARKLKSLPQKTYSEDEIDDNYYDPSSDSQDSGESKFKCKICLKRYSTQKGLKKHSLVHEKKYKCDVCLKMFYKQENMKNHKKIHSSKPLACKLCHACFSKPQSFARHLKSHTEKLNNMIKQINTDDQKDSKEVRKEAKPDEDTDDESGTVNEVDEFENAPELYKCDICSQYCSSLKNLKRHALVHGDKKYSCTVCKKWFFRPDTLKKHAEKHGHGLLDNLVEDNKFFDSDDDPFPNTVTNTSQESESVKKEESDEDGSGEYKCQHCDKIMATKKGLRRHVAMHKPKAEPVTCEICRKVCASQARLVLHQRTHKPKEKVPREYLCHICSKVYPSNSSLTYHMRTHTGVKPHVCKTCNSGFTTTTSLANHIRIHTGDKPFVCHVCSAAFAVSSAFRRHLTRHTGEANYLCKTCGKAFKRLSTLKEHTYTHSGEKPYVCKTCGAAYSHSGSLFAHQKRCRAQYGEMVVDDHHHQVAHHIHVNNVQSAVRSLAVIGQMF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00962662;
- 90% Identity
- iTF_00085619;
- 80% Identity
- -