Apra027456.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Andrena praecox
Gene Symbol
ZNF496
Assembly
GCA_963932275.1
Location
OZ010731.1:56630523-56636293[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 29 1.2e-06 0.00018 22.8 3.2 1 23 333 355 333 355 0.99
2 29 4e-06 0.00058 21.2 1.1 1 23 361 384 361 384 0.95
3 29 3.8e-05 0.0055 18.1 0.9 1 23 390 412 390 412 0.99
4 29 6.9e-05 0.01 17.3 0.9 1 23 418 440 418 440 0.96
5 29 0.00064 0.093 14.3 2.9 1 23 446 468 446 468 0.97
6 29 0.00017 0.024 16.1 0.5 3 23 476 496 474 496 0.97
7 29 0.007 1 11.0 3.7 1 19 602 620 602 621 0.95
8 29 0.011 1.6 10.4 0.9 1 23 678 701 678 701 0.92
9 29 0.0017 0.24 13.0 1.5 1 23 733 755 733 755 0.98
10 29 2.5e-05 0.0036 18.7 1.5 1 23 761 784 761 784 0.96
11 29 6.6e-06 0.00096 20.5 0.3 1 23 790 812 790 812 0.98
12 29 2.5e-07 3.7e-05 25.0 1.0 1 23 818 840 818 840 0.99
13 29 3.5e-05 0.0051 18.2 0.7 1 23 846 868 846 868 0.98
14 29 9.9e-06 0.0014 20.0 1.4 1 23 874 896 874 896 0.96
15 29 3.8e-06 0.00055 21.3 0.9 1 23 1009 1031 1009 1031 0.99
16 29 3.3e-06 0.00048 21.5 2.4 2 23 1038 1060 1037 1060 0.95
17 29 0.0055 0.8 11.3 0.9 1 23 1066 1088 1066 1088 0.97
18 29 0.00023 0.033 15.7 4.4 1 23 1094 1116 1094 1116 0.94
19 29 0.00018 0.027 16.0 2.3 1 23 1122 1144 1122 1144 0.97
20 29 1.4e-05 0.002 19.5 2.4 1 23 1150 1172 1150 1172 0.98
21 29 0.011 1.5 10.4 0.1 2 23 1206 1228 1205 1228 0.95
22 29 1.2e-05 0.0017 19.8 1.7 1 21 1297 1317 1297 1318 0.95
23 29 1.1 1.6e+02 4.1 1.0 1 23 1347 1369 1347 1369 0.95
24 29 0.00022 0.032 15.7 0.6 2 23 1376 1398 1375 1398 0.94
25 29 0.00071 0.1 14.1 0.0 1 23 1404 1426 1404 1426 0.97
26 29 0.00097 0.14 13.7 1.4 1 23 1432 1454 1432 1454 0.97
27 29 0.0097 1.4 10.5 10.2 1 23 1460 1482 1460 1482 0.97
28 29 7.7e-05 0.011 17.2 0.0 1 23 1488 1510 1488 1510 0.96
29 29 0.024 3.5 9.3 3.1 5 23 1519 1537 1517 1538 0.93

Sequence Information

Coding Sequence
ATGGAACCCGAGAGTCCCGTTATGTTAGACTCGTGCGCGGACGATTGCATTTTAATTCAAACCGTGAAGAGCATGGTCACGCAGAACACGCACACCGATTTGGAAAGCGACGAAGAATTCTTCCTTGTATCGGACGACGTTCAGGAGGAACAACAAAATGTAACGGAGGCGTCGAACCAGGAGGCCGTGGCCGTTCAGTCCGAAGAGCGATTGCCGTGGTCCGCTTTGTGCCGAGTGTGCGCTAACACCAGCGATCATTTAATTCCGATATTTGACGGAGAAGGTTTGCAGCATGATTTATGCAATAAACTACACAAGTATCTACCTATACGCGTATCCGAAAGCGACGCGCTTCCGTTACAATTATGCTATCACTGTGCCGCTACGTTGCTAGCGTGGCACGAGCTCTTAGAAGGATGTCTGAGCGCCGAAAGACGCCTCCTACAAATGCAAGTCGCGTCGCAAGAAAGACAGGGTTCGGATGGACTAGAGGCTTCTATGCAAGACACATCGGTGTCTAATGTTCCAGAATCTCCTCATCGACGGCAGGAAACTGTAAAGGATGAGAGTTGCGAAGAATTGGCTGTTAACGATTCGAACAGGTCCAGTAATATGCGAACACCGTTTAAGGTGTTCCTAGACACGCAGAATATATTTCGGAAGCCATACAGAAAAAAGTGCCAGCTAGAAGAAAGAAAGCCTGCGGACAGTGGAGATTGCGATTCAATGTGGATCACTGCCATGAACTCGACGCTCGATCCAGCGGCAGTAACGTCTGATCCCCTGCTAATTAACGATATGAATGAGAGAGCAGAGGTTTCCCAACTGTACAGATCGAACGGCGTAGATAATGAAACGGGCAGGCCGACAGACGTTGCGGATGCGAGAGACGGCAATGAAAGAACGAACGGAGAGGTTCGTGTCAGCGATATAAGAAGCTCTATAGAGCCTGGCGAGCATGCGAAGCACAAAGCTACCAGCGACGCTCCAGAAACTTATCAATGCGTAGAGTGCGGAAAGTGTTTTAAGTTAAAGGACTCGTTTCTGAGGCACATGAGAATTCATAGGGACGAAAGGCCGTTCACTTGCCACGTGTGCGGGAAACAGTTTCGAGATTCCGGTGGCCTATCCAGGCACTTGAAAGACGTGCACGCGAAGGTGAAGAACTTCACGTGCGACATCTGCGAGAAATCGTTCGCGTCGAAGGCCACGAGAGAGGACCATCGTAGGACCCATACAGGAGAGAGACCCTATATATGCGACTCGTGCGGAAAGACGTTCAAGTCGAAAGCTTCCCTGTATATTCACAGTAAACTACATACAGACGAGTTCCCCCATCCGTGTTCCTACTGTAGCAAAAAGTTCCGTAGAAGGCAAGAGATGCTGGCCCACGTGACCACTCACACGGGGGAAAAGAATTACGGCTGCGACGTGTGCTCGAAAAGATTTCGGGTGAAGTCGGAGCTGGTTAGGCATAAGCTAATTCACTCGGAAAGCAAGCCgTTTGGTCTACCTCAGAAGAAATCCTTCGCGGCATACTGTTCGCGGCATGTGACAGCGAAGTGTGCAAATAGTATAATACAGACCGATATTAAATGTAGAGTTCCCCGGAATCGCGACAGAGCGAATGCCGAGGAGAGCGCGAGGGAGAAAGCTAACAGCGACGACAGCACGAACTACTCCGCCAACTCTGACAGCGCGGACTTAGATATGACAGAAACGATGAGAGCCATGCTATCTCCTAAAGAGCGCTCCAATGAAACTGCATCTTCGGCAAAAACAAGTGCTAGCTCGCCAAAGAAACACATATGCGAGAATTGTCAGCGAACTTTTAAAAGAGAATGCCACTTAATGCGGCACGCGCCCAAATGCAAGACAAAAGCGGGAGATAGTACCAAGACGATTGACGCGCGCTGTAAAGACGAACGCATATCGAGTGATTCCGATAAAAGCAAGGAGGAAAGCACAAAGGACGAAGGcagaaggaattggaagctgtACCAGGCGTGTAAAAGAAAAAGGCACGAAACGCATCCTTGCATGTATTGCGACTACACcagcaagaagaagaagctgTTGGAGATTCACATAGCGGAGTCGCATCCAGAATTCACGCGGAAGAAAGACAAGAAGCTTCGATGCATCGATAGAGAGCTGGTGATGCGTGCTAAGATGGAGGTAGATGGAAAGATCTATTATCACTGCAACGAATGCGGCAAGAACCTCTATTCGCCGTACACGTTCTACTGGCACGCGCGGATCCACACCGGAGAACGTCCCTACACTTGCCACTTGTGCGGCAAGCAATTTCGCGTGAACCAGGGCCTGGCGAGGCACTTGAGGGACACTCACGCGGGCATCAAGAACTTCCCCTGCGACATCTGCGGCCGAATGTTCACCACGAAACGGAACGCGGAGGATCACAGGCGGATCCATACCGGCGAGCGGCCCTACGTATGCAACGTTTGCGGGAAATCGTTCAAGCAGAAGGCCTCTCTGTTCGTGCACAATCGCACGCACTCGGACGTGTTCCCTTTCAAGTGCAACTACTGCGACCAGAGTTTCCGTACGCGGCCGCCGCTCGTCGTTCACATAACGAAGCACACGGGCGAGAAGCCGCACGCGTGCGACATATGCGGCCGTTCCTTCCGCATAAAGTACGAGCTGAAGCGTCACCGTCTGATACACTTCGACGAGAAACCATGGCAGTGCACCGAGTGCGATCTCTCGTCTAGAGCTCGTGCCGATCTCGACGCGAAACGCGACTCGGGCGACTCGCTAGACGACCAGCATTCGGAAAGACGAGATAACGATTCGCGACCGCTTACAAAGACTGATACGAAGAAACGTATACCCTCCAACGGTGACGTCGATAGTCCCGGAGAAGAGAAGATCCAGCGGAGAGAGAATCTGGAAACAGCCTCCGAGAAATGTGCGAAGCGCGTGGCGTCTTCGTCGAAACGAAGCCTGGAGCAACGGGACGAACTGGCCCGCTCGAAACTCACGGTGAATGGGTCCGCGCACTATCAGTGTAACGATTGCGGGAAAATACTGTCCACTTCGTACAACTTTCTGGTCCATCGTAACACTCACACCGGGGAGAGGCCGTGCACGTGCCACGTGTGCGGCAAGGGCTTCCGTTCTGCGTCCGGTTTGAATAGGCACGTGCGGAATGTTCACGCGGGGATGAAACAGTTCGCCTGCGACATATGCGGCCGTTGCTTGGCCTCGAAGGCCTCGCGGGACGAGCACAGGCGCACCCACACGGGGGAGAGGCCGCACGTGTGCGAGACCTGCGGGAAATCGTTCAAACAGAAGGCATCTCTGCACGTTCACAAGTCGTTCCACTCGAACCGATTCCCTCACAAATGCCCGCGATGCGAGCAAAGCTTCCGGCGGAAGCAGGAGCTAGACAAGCACGTTTCCGTGCATACCGAGCAAAGGCCGTACCCTTGCGACGTGTGCGGGAAACGGTTCCGTACCAAGGGCTGTATCAATCGTCACAAGCGCGTCCACAGCGGCGATCGTGGGTCGTTGAAGACCGAGCCGGGAGGCGTCGCGCGTACACCCACGGCCGATAATGATAGTACAAACGACGAGGAGGCAGAGTACGTCCAGTGCGCTCAGTGCGATATCGTTTTCGTCAGCATGAAGTATTTCATAGATCACATGAACGCCGAGCACGAGGCTCAGATGCATTATTGTCAATATTGTAAGCTGATGTATCACGGCAGAGACAGGGACTTCGTGGAGCACATGACGATTCACAGTTTCGACATCGAGGAGTCGAAAGAAGCCGTGAGAGATGTGATTGCCATTAGCGGGAACGACGTGCGGAAAGAAGACTTGCATGCCGAGGATGCTGCCGGTGACGTGACAGAAGAGTCCTTCACTTGCAACTTGTGCAGCCGAAGCTTCACGAAAAAGTCCGAGTTGAAGAAGCACATAAGCAGGTACTCGTACATGCACCGGGTCCAAAATTCCGACGAAATGGAACTGTTGGACAAAGCGAAGCAGACGATCAACGCTCGGGTCTCCTACAAGTGCATCACTTGTAAGAAAGTTATACTCACGAAGCGCGGCTTTCTGCGTCACATTCGCGTTCATTCCGACAAGCGGCCGTGCAAGTGCGACATATGCGGCAAGTCGTATCGAATCGAGCAGGACCTGGCTAGGCACGTGAGGGACGTTCACGAAGGCTTGAAGAAGTACGCCTGCGATATCTGCGGCCGCGCGTTCGCGAACAAAGGCGCCAAAGATGACCATCGGAGGATTCACACGGGGGAACGACCGTACGCGTGCGAACATTGCCCTAAAACCTTTCGCACGCTGAATTCCATTTACATTCACAATCGCGTGCACACGGACTACAAGCCGCACAAGTGCTCCTACTGCGACAAGCACTTCAGGAGCAAGCAGAGGCTGACCCACCACGAGACCACGCACACGCGCGTCAAAGCTTTCGCCTGCGAGATCTGCGGCAAATCGTTCTCCGTCAAGGGGGAAGTTGTCCGGCACAAAGCGATACACAACGAGGAGAAGCCGTTCGATTGTAAATGCGGCATGAAATTCGGGCAGAAGAGATACTTGAGGAATCATATAAAACAGCACCACAAAGAGGCGTCCTCGTGGTTGATAGAGGAATTACTGGGGGATAATAACTGA
Protein Sequence
MEPESPVMLDSCADDCILIQTVKSMVTQNTHTDLESDEEFFLVSDDVQEEQQNVTEASNQEAVAVQSEERLPWSALCRVCANTSDHLIPIFDGEGLQHDLCNKLHKYLPIRVSESDALPLQLCYHCAATLLAWHELLEGCLSAERRLLQMQVASQERQGSDGLEASMQDTSVSNVPESPHRRQETVKDESCEELAVNDSNRSSNMRTPFKVFLDTQNIFRKPYRKKCQLEERKPADSGDCDSMWITAMNSTLDPAAVTSDPLLINDMNERAEVSQLYRSNGVDNETGRPTDVADARDGNERTNGEVRVSDIRSSIEPGEHAKHKATSDAPETYQCVECGKCFKLKDSFLRHMRIHRDERPFTCHVCGKQFRDSGGLSRHLKDVHAKVKNFTCDICEKSFASKATREDHRRTHTGERPYICDSCGKTFKSKASLYIHSKLHTDEFPHPCSYCSKKFRRRQEMLAHVTTHTGEKNYGCDVCSKRFRVKSELVRHKLIHSESKPFGLPQKKSFAAYCSRHVTAKCANSIIQTDIKCRVPRNRDRANAEESAREKANSDDSTNYSANSDSADLDMTETMRAMLSPKERSNETASSAKTSASSPKKHICENCQRTFKRECHLMRHAPKCKTKAGDSTKTIDARCKDERISSDSDKSKEESTKDEGRRNWKLYQACKRKRHETHPCMYCDYTSKKKKLLEIHIAESHPEFTRKKDKKLRCIDRELVMRAKMEVDGKIYYHCNECGKNLYSPYTFYWHARIHTGERPYTCHLCGKQFRVNQGLARHLRDTHAGIKNFPCDICGRMFTTKRNAEDHRRIHTGERPYVCNVCGKSFKQKASLFVHNRTHSDVFPFKCNYCDQSFRTRPPLVVHITKHTGEKPHACDICGRSFRIKYELKRHRLIHFDEKPWQCTECDLSSRARADLDAKRDSGDSLDDQHSERRDNDSRPLTKTDTKKRIPSNGDVDSPGEEKIQRRENLETASEKCAKRVASSSKRSLEQRDELARSKLTVNGSAHYQCNDCGKILSTSYNFLVHRNTHTGERPCTCHVCGKGFRSASGLNRHVRNVHAGMKQFACDICGRCLASKASRDEHRRTHTGERPHVCETCGKSFKQKASLHVHKSFHSNRFPHKCPRCEQSFRRKQELDKHVSVHTEQRPYPCDVCGKRFRTKGCINRHKRVHSGDRGSLKTEPGGVARTPTADNDSTNDEEAEYVQCAQCDIVFVSMKYFIDHMNAEHEAQMHYCQYCKLMYHGRDRDFVEHMTIHSFDIEESKEAVRDVIAISGNDVRKEDLHAEDAAGDVTEESFTCNLCSRSFTKKSELKKHISRYSYMHRVQNSDEMELLDKAKQTINARVSYKCITCKKVILTKRGFLRHIRVHSDKRPCKCDICGKSYRIEQDLARHVRDVHEGLKKYACDICGRAFANKGAKDDHRRIHTGERPYACEHCPKTFRTLNSIYIHNRVHTDYKPHKCSYCDKHFRSKQRLTHHETTHTRVKAFACEICGKSFSVKGEVVRHKAIHNEEKPFDCKCGMKFGQKRYLRNHIKQHHKEASSWLIEELLGDNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00085599;
90% Identity
iTF_00085599;
80% Identity
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