Basic Information

Insect: Andrena marginata
Gene Symbol: Bcl11b
Assembly: GCA_963932335.1
Location: OZ010659.1:19612562-19615491[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0021 0.18 12.6 0.2 2 23 67 89 66 89 0.96

2 6 1.5e-07 1.2e-05 25.7 1.7 1 23 404 426 404 426 0.99

3 6 0.0031 0.25 12.2 0.2 2 23 447 469 446 469 0.96

4 6 1.2e-07 9.9e-06 26.0 2.9 2 23 672 693 671 693 0.97

5 6 8.6e-06 0.00071 20.2 3.3 1 23 699 721 699 721 0.99

6 6 3.9e-05 0.0032 18.1 0.4 1 22 729 750 729 750 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0021	0.18	12.6	0.2	2	23	67	89	66	89	0.96
2	6	1.5e-07	1.2e-05	25.7	1.7	1	23	404	426	404	426	0.99
3	6	0.0031	0.25	12.2	0.2	2	23	447	469	446	469	0.96
4	6	1.2e-07	9.9e-06	26.0	2.9	2	23	672	693	671	693	0.97
5	6	8.6e-06	0.00071	20.2	3.3	1	23	699	721	699	721	0.99
6	6	3.9e-05	0.0032	18.1	0.4	1	22	729	750	729	750	0.97

Sequence Information

Coding Sequence: ATGCTCTCGAGGTTAGGTCCGACGGTGTTTCCAAGCCGCGAAGTAAGGGTGCTTGTTGCGGAGGCAGATGCCCAGCGCCTGTCCTTTTCTCCAGGCTCTTGTTCACCGCTCGCCTCGGAGGGTGGCCTCGAATTAATAAAATCCCACGGTCACCCCCCGACCCCGCGGTGGAGTGGCGTCTCTGAACCCAGATGGCTGCAGTGCTCGCAGTGCTCCAGAAGACTGTCCTCCGCGTGGGAGCTGCTGCAGCACATCCAGAGCGTGCACGGCGCCAGGCTGTACACCTCCCCGTCGTCGTCGACCAACTCCTCGTCGAACACGCCTGCACCGAGCCCGCCGACGCCCACCCCGACTCACGCCCACCACCTGAGCCCGCCGAACCACCTGAACCTCAGCGGCAAGTCCACCGGGAGCTCCTCGGCGGCGAACTCCTCTGGCGGCACGAACTCGAGCGGCAGCAGCGGCGGCCGACAGCAGCTGCAGTCGTCAGCCTCCCTCGTCGGTGACCCGCTTCACAGTTTCCTCAGGCTACCGCAACACCTGGAACGAAGCTTCCCGCCGATGTTCAGGCCCGACTTCCTAGCCCTGAATCCGCTGGCCGGGTACAGAGGGCTGCAGGAGCTGCAGACCGCTACCAGGAACCTGCAGAACCTGGGGGACCCTTTGCGGGGCATGGACGGCTTGAACCTCGGTGATCCGCTGGTTCGCAGCTCGTTGGACTCCCTGAACAACGCCCGCAACCTAGCGAATCTGGCCGAGTTGTCGCATGGCCGTGGCCTAGCGGGGCAACCGCATCCACCACCACTAGAGGCCAACCTGGATTTTTACTCGGCGCGCCTAAGGAGCCTCGCTAATCCGTCCTTAGGCGCGGCTCCACCCAGTAACGGTAACACTACAACGAGCTCCAACCCCCCGGCCTCGGTACCGCCTGTACCAGTGCCAAGCACCgtccagcagcagcagcagcaacagcagcaacagcaacagcagcagcccGTGCAGAACCACAGCCAACCCGTAGAGCCTCCCAGCCCGGCGCCCAACAACGCCACCATCCTGACGCACGGGAATCATCAGAAAGAGAACTCCCCGCCGTGCTACAATCAGAGTCCAGTTGggcacaacaacaacaactcgACCGACAGCGAGAAGACCAGCCCGCCGGTCGCCTCCACGCCGATCATCGCTGATTCTGCGTCGGAGATCATCTACACGTGCGAAGTGTGCGACAAGAAGTTTCGGTTCCAGTCGAACCTCATCGTGCACCGCCGGAGCCATCGAGACAAGGAGAGGCAGTACCAGCAAGACGGCCCGCAGGACCACCAAACGACGCCCACCAGGTGCGAAGTCTGCGAGGTGGAGGTGGCCAGTTTCACGGAGCTGAGGAAGCACATGAGGAAGGAGCACCAGGAGAACCTCAGCGCCGCTAGCCCTCAGGGTAGCGTGGAGACCGTTCCCGATGACGGTTCCAGCTGCGACGAGAATATGGACCTCGACGAGGCGGACGAGAACGAGCAGAAGACGGAGCGAGAGGACACCGAGGAGAACACGCCCGAGGATCTGAGCACCACCCAAGGTCAGAGCGGGGAAGAGAGCGGCGGCAGAGTGGACCAGAAGCCGGCCAGCCTGGTCGGCGATCTGATGGAGAAGTTCGGGTTGAGCAACATAGCGCAGTACTCGGAGGCGTACAGGCAGGCACTGCAGGAGAACCATCGCGGCGGATTCATCAAGACGGAATCCCCGTCGAACCTAACCAACTCTCTGAATAACAACAAAGAGAAAGACAGCGCTCTGTCGCCCACGAACTTCAATTCCTCGACCACACCCAACATATTCTCCGGTCAGGGTTTTCCCAGGTCCTCGGGGCCGGACTTCGGCGGCCTGTGGCTGCCCAGCCCCCATTACCTGGAGAACAACGAGTTCCGGAAGGCGACCAAGGCCACCACGTCGAGCCTGGCCCTCCAGGGCCTGCCGAGCCCGATGCTGAAGAAGGAGCGCAGCGGTAGGAACGACACGTGCGAGTACTGCGGCAAGGTGTTCAAGAACTGCTCGAACCTGACGGTACACAGGCGGTCCCACACCGGCGAGAAGCCGTACAAATGCGAGCTGTGCTCGTACGCATGCGCCCAGAGCTCCAAGCTCACCAGGCACATGAAGACCCACGGCAGACACGGCAAGGACACGTACAAGTGCCGTTTCTGCGAGATGCCGTTCTCGGTGCCCAGCACCCTCGAGAAGCACATGAGGAAGTGCGTGGTGGTGGTGCAGCAGGGCCCCAAGCTGGGCATGCCGTACCCGGGCAGCCAGGACGAGGACTCGTCGCTCAGTACCAAGGACACTTGA
Protein Sequence: MLSRLGPTVFPSREVRVLVAEADAQRLSFSPGSCSPLASEGGLELIKSHGHPPTPRWSGVSEPRWLQCSQCSRRLSSAWELLQHIQSVHGARLYTSPSSSTNSSSNTPAPSPPTPTPTHAHHLSPPNHLNLSGKSTGSSSAANSSGGTNSSGSSGGRQQLQSSASLVGDPLHSFLRLPQHLERSFPPMFRPDFLALNPLAGYRGLQELQTATRNLQNLGDPLRGMDGLNLGDPLVRSSLDSLNNARNLANLAELSHGRGLAGQPHPPPLEANLDFYSARLRSLANPSLGAAPPSNGNTTTSSNPPASVPPVPVPSTVQQQQQQQQQQQQQQPVQNHSQPVEPPSPAPNNATILTHGNHQKENSPPCYNQSPVGHNNNNSTDSEKTSPPVASTPIIADSASEIIYTCEVCDKKFRFQSNLIVHRRSHRDKERQYQQDGPQDHQTTPTRCEVCEVEVASFTELRKHMRKEHQENLSAASPQGSVETVPDDGSSCDENMDLDEADENEQKTEREDTEENTPEDLSTTQGQSGEESGGRVDQKPASLVGDLMEKFGLSNIAQYSEAYRQALQENHRGGFIKTESPSNLTNSLNNNKEKDSALSPTNFNSSTTPNIFSGQGFPRSSGPDFGGLWLPSPHYLENNEFRKATKATTSSLALQGLPSPMLKKERSGRNDTCEYCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRHGKDTYKCRFCEMPFSVPSTLEKHMRKCVVVVQQGPKLGMPYPGSQDEDSSLSTKDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00086621;
90% Identity: iTF_00088302;
80% Identity: -