Basic Information

Insect: Anastrepha obliqua
Gene Symbol: zfh2
Assembly: GCA_027943255.1
Location: JAPTHQ010000247.1:927617-933039[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.71 1e+02 5.0 0.2 1 21 112 132 112 135 0.88

2 5 0.0018 0.26 13.2 0.2 2 23 309 331 308 331 0.95

3 5 0.13 18 7.4 0.1 6 23 466 484 466 484 0.96

4 5 0.00031 0.043 15.6 3.9 1 23 497 519 497 519 0.98

5 5 0.00047 0.065 15.0 1.5 2 23 526 548 525 548 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.71	1e+02	5.0	0.2	1	21	112	132	112	135	0.88
2	5	0.0018	0.26	13.2	0.2	2	23	309	331	308	331	0.95
3	5	0.13	18	7.4	0.1	6	23	466	484	466	484	0.96
4	5	0.00031	0.043	15.6	3.9	1	23	497	519	497	519	0.98
5	5	0.00047	0.065	15.0	1.5	2	23	526	548	525	548	0.94

Sequence Information

Coding Sequence: ATGTATGTTCACAAAACTAATAATAACACCTTGTTTATTCCCGCAGATAACAGTAAGTTAGAAAATATCAGATCGGTTTCAGTTCCCGGCTATTTTTCTGTCCCCACGACGCGGTTAACTAATGAAGACAACGCATATAACATATCTGTAATTGATCACAACTCCTTCTCACCATCATCAAACTCCTCGATTGCATCAGGAAATACAAGTGTACGTAGCAAAGGATACCAACGTGTTAGTACACCAAATTTTCAGTCATCTATTGGGGATAGGGATGGTTTAACCACAACTTTGGGTTCGGCCATTAATACTACTGGCATACCATCTGTAATTTTTAAATGCAACAACTGTGATTTCTTTGCACAATCCAAAACAGAGATGGAAATACACCTAGGAGCAGTTCATCCCCAAACGGAACCAGACTACATCAGCATTCCAACGAACTCCGTGGCAATGCAAGCATTTCAAGCCGCAGTAGCAGCAGCTACAGCTGCAGCAGCGTGTGCAGTAACTGCTACACACTCTGGTAGTAGCAAATCCAATTTCGAAAATGATGCTATTGATGACGATTGTCCAACTTCAGTAAAGAGAGAACGTTTATTTTTGCCTGAAGATGAGGAGTTCGAAAATGGAGCGGACATGAGCAATACATTGGCTTTGCAAAATGCATCGACAATTTCTCCTTGGATCACAACAACAATAAACACGAATGAATTTTCACCATCAATAAATGAATCAAGATCAGGAAGTAATAATGTTATAAGTAGGGAACTTGAGGAAAATGAAAGTAATAATGTCATAAGTAGGGAACTTGAAGAAAAATTGCAGCAACATCAATCAGTGCTCAAAAGCATTAAGATAGTATCAAATGATATTGATGACAGTAGTCAGGTTGACCAAAGTAGCACAAATTATGCCAATGTTCAATGCCCATTATGCACTGGCACATTCGACCGTAAGCAAACACTAGAATCGCATTTGATGAATGTACACAGCGTAAATCGCGATGGATTAGCACGACTCTTACAACTGGTGGACACCAGCGTTTGGAAGCATTTTCACACAGAATCAGCAAGTGTCGATGCTGCCGAAACTGTCAGACCTGCCACCGAAACAAACACAATCAAAGATATAAATAATGCAGGTTCAACGGAATTAAACTTATCAACGATGGCAGTCTCAACCGATGCATCCATAAATCTCAATACTTCTAATCCAACAGCGTACATTCAATCACTGGAAGCCGTAAATAGTAGTGAACTATCATGTGAACAGTGTTGCATGCATTTTAAGCATGAACAACAATTGTTGCTACATGTACAAAAATTTCAACATTTTGTGGTCTTGCCAAATGGAGATCACCGTTGTTTGGCTGCTAGTCATCCCAGCCGACCTTGCCACGCGACATTTCCCTCGCAAGCTGCTTTGATCGCCCATTATAAAAATGTACACATAAGTTTAATTATATCAGAGCGTCATGTATACAAATATCGCTGCAAGCACTGCTCACTTGCATTCAAAACTCAAGAAAAATTGTCCACCCACTTGTTATATCACACGATGCGCGATGCTACCAAATGTACATTGTGCCAGCGAAATTTTCGCAGCACACAAGCGCTACAAAAACATATGGATCAGATACATAGCAAAAGTAACCAACACGTTTCTAGTTCACCAACATTATTAAGTTGCAGCAGCCGCGGGTCGCCAACTTTTCGTACAACAAACTCGCAAATAACTGAGGCAGTTCTGGATAATGCACCTAAAACTAACGACGGTGATGCTTGTCAGTCGCCACCCATATCACCACATAGCAAGGAACAAATGGATTCCAAGAACTTGAATGAAACATCACAAGCATCATCTTCCCCATTAACAGCTCACATATTGCAGGATCAGCAACAGCACGTCGCTGCATTCACCGCTGCACTACTAAATCAGTCTTCACAACAGCAACACTGCAGCAGTGATGAATTAGCAGTGATTACACAAGCTCATCTAATCCAACATTTACAAACTAAGCCCAGTGGATCGCTGTTGGCGCAGAAATACATTCAGCAACAACAACAAAAACTACAAAATATTCAACAATTACAACAGTTGCCGCAGCTGACAGGCGCTTCCACCGGTTTGCCACTGAATCCCGTCGAGATGCTAAATCTCATGCAATTTCACCACATAATGTCCATGAATTTCATGAATCTTGCTCCACCGCTTATATTTGGGGTTGGCGCTAATGCTAGCGCTAGCAACAATACAGAGTTGGTTACGTCTCCACACACACCTAAAGTAGCTCACAATTGCGGTGCCCATACGCTTCTCTGCGGAAGCGATTTGACTATACCAGGCACTCCAGTTCCAGTCGGGTCAACTGCGGATATTATTGGTACATTACCAAAGCAGCAACAATCTCAACAACAACAATCTGTAGCAACAAGCATTTCACAGATGGCGAGTAATCAAAAACGTGCACGAACGCGTATCACTGATGAACAGCTAAAAATCCTTCGTGCACACTTTGACATCAATAACTCTCCAAGTGAAGAAAGTATAATGGAAATGTCTCAAAAGGCAAATTTGCCTATGAAGGTACAAGTTCTTCTTATTCATCATACCGTGATGCTGTTAGATCAAGTCATTAGTGTGGAAATGCTGCTAGAGTGA
Protein Sequence: MYVHKTNNNTLFIPADNSKLENIRSVSVPGYFSVPTTRLTNEDNAYNISVIDHNSFSPSSNSSIASGNTSVRSKGYQRVSTPNFQSSIGDRDGLTTTLGSAINTTGIPSVIFKCNNCDFFAQSKTEMEIHLGAVHPQTEPDYISIPTNSVAMQAFQAAVAAATAAAACAVTATHSGSSKSNFENDAIDDDCPTSVKRERLFLPEDEEFENGADMSNTLALQNASTISPWITTTINTNEFSPSINESRSGSNNVISRELEENESNNVISRELEEKLQQHQSVLKSIKIVSNDIDDSSQVDQSSTNYANVQCPLCTGTFDRKQTLESHLMNVHSVNRDGLARLLQLVDTSVWKHFHTESASVDAAETVRPATETNTIKDINNAGSTELNLSTMAVSTDASINLNTSNPTAYIQSLEAVNSSELSCEQCCMHFKHEQQLLLHVQKFQHFVVLPNGDHRCLAASHPSRPCHATFPSQAALIAHYKNVHISLIISERHVYKYRCKHCSLAFKTQEKLSTHLLYHTMRDATKCTLCQRNFRSTQALQKHMDQIHSKSNQHVSSSPTLLSCSSRGSPTFRTTNSQITEAVLDNAPKTNDGDACQSPPISPHSKEQMDSKNLNETSQASSSPLTAHILQDQQQHVAAFTAALLNQSSQQQHCSSDELAVITQAHLIQHLQTKPSGSLLAQKYIQQQQQKLQNIQQLQQLPQLTGASTGLPLNPVEMLNLMQFHHIMSMNFMNLAPPLIFGVGANASASNNTELVTSPHTPKVAHNCGAHTLLCGSDLTIPGTPVPVGSTADIIGTLPKQQQSQQQQSVATSISQMASNQKRARTRITDEQLKILRAHFDINNSPSEESIMEMSQKANLPMKVQVLLIHHTVMLLDQVISVEMLLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00082828;
90% Identity: iTF_00081107;
80% Identity: iTF_00082828;