Basic Information

Insect: Anastrepha fraterculus
Gene Symbol: lola
Assembly: GCA_037575425.1
Location: JAYXIM010055515.1:86217-133112[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.00015 0.021 16.5 1.9 1 21 503 523 503 524 0.96

2 5 0.00092 0.13 14.1 3.9 2 23 533 555 532 555 0.96

3 5 0.0092 1.3 10.9 3.9 1 23 945 968 945 968 0.95

4 5 0.0017 0.23 13.2 1.3 1 21 1653 1673 1653 1674 0.94

5 5 0.017 2.3 10.1 3.8 1 23 1683 1705 1683 1706 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.00015	0.021	16.5	1.9	1	21	503	523	503	524	0.96
2	5	0.00092	0.13	14.1	3.9	2	23	533	555	532	555	0.96
3	5	0.0092	1.3	10.9	3.9	1	23	945	968	945	968	0.95
4	5	0.0017	0.23	13.2	1.3	1	21	1653	1673	1653	1674	0.94
5	5	0.017	2.3	10.1	3.8	1	23	1683	1705	1683	1706	0.95

Sequence Information

Coding Sequence: ATGGAGGATGATCAGCAGTTTTGTCTCCGATGGAATAACCACCAGAGTACGCTGATTAGTGTGTTTGACACATTATTAGAGAACCAAACTCTCGTCGACTGTACATTAGCTGCGGAAGGGCAATTCCTAAAAGCTCATAAAGTGGTACTGTCTGCATGCAGTCCATTTTTTGCTGATTTGCTTCAACAGCAGTATGATAAACATCCGATATTCATATTGAAAGATGTGAAATACCAAGAATTGCGTGCCATGATGGACTACATGTACCGTGGAGAAGTGAATATTTCACAGGATCAATTGGCTGCATTGTTAAAAACTGCAGAGTCGCTGCAAATAAAAGGCCTGTCAGACAATCGCAGTGGTAGCACGCCGAAAACAGAACAACATCGTGGTTTAAATGTACATGGAAGTGGTAGTGGCGGTAAACTGAGCGTATATACACTCGAGCAGACGCAACCTAAACGTCCTCGCGTTGGGCCGTCTCCTATGGAGACTACAGATATATCAGGCTCTCGGGAGGGTTCATCTAGTCCATCTAGACGTCGAAAGAAAGCTAGACGCAAGAGTGCCGAAAATGCTATGTCTGcaGACGTTCATGACAATTCCAACTCATCTCAAATTAACCAATCGTCACTTCAGCCacatcaacaacaaccacaagcCAATGCAAGTCTAACTGGGGTTGGAGCCATAACGGCAGCCACGTCTTCACTTCCAGTCTCAGCATCCGCATTATCGACCGGTACAAGTGGTGTTTTAGCAGCAACTGGTTCAATAGTTAGCACACAAGGAACTACTCAGCAAATGACCACAAACATTACCAAAAAGACTGAAAGCGTTAAAGGAGCAAGCGATGCCATGCATACAGAAAATATACAGGCTGTGGGTGTGGTTGGTACCGGGGACGAACAAAACGTAGAGCATGTTAAGGGTGAAAAATCTAATCATAAACAAAAGCCGTCGACAGCCGGAGTTACTGGTAAAGAAACTGCCGATTTGGTAATCGAACCGAAAAGTGAATATGAAGAAGAAGGCAATGAGGAAACTGTTGAAGATCTGACTCTAGACGACGAGGAAATGGGGATAGAGGATTTAGATCATAATGCCGGTACAAGCCAAGCCGGCGAAGGATCTAGTCAAGGGTATGCACCGTGGCAACATGACAGATCTCAGGACGAGTTATTATTGGCGCCACAAGAGACACAGCAACGGGATCCACAAGGATATTTCCCCTCCTTCGCACATTCAACTAATAGTACTATCATCGCCACCAACTCCAATTCAAATACTCGTCCATCCGGCGCTACATTTACGAGACCACCACTATCACCACCACAACAACAATCGTTAACAGCGAATATACTTATAGATAACAAAAATAGTAACGCATTTCAAAATAATCCTCAAGAAAGCCATGACATCACAATTGAAAGCACTGAATCGATATTCTCAGGCAGCATTGCTATAAGTTCACGTTACCAGATTCTCGATAATTCCGAAGAGAACTATGAGTGTCCACAATGCTATCGAACCTATAGGCGCCATGGCACCCTGCGTCGTCATCTGCGTCAAGAGTGTGGTAAGGGTAAAAGCATGGTGTGCTCGGTGTGTGGGCACAGGACAAAACGTGCCGATCATTTACGCCAACATGTTCGGAAAAAGCATCCTGAAATGGCGATGCGCTCTTTGTTTCGGCGGCCAACAAGTGCCGCTGGTAGTAGTAATCATGGCATCCGAACACATGGGTTTGGACATCGCCTACCGCCCCAACAACGCATGCAACAACTCTTGCAGCGATCATTATCACCGCCAATCTTGCCGTATTCTGAAATACACGGCCAGCAGTTGCAAGAGCCGTTAGTTGCAACAAAAACGCTTCCATTCAATACGACTTCTACGTCAGATGCAGCCAGTTTTATGGGTGTTGATGTGGTCGATTTGGACGCGGAAGGTGATAATAATGGCGACGACAATAAGAAAAGTGATTCCGACAAGTTAGATTTAGAGCACGACAAAGTCAAACAACAGTCGCGTGCGGATTTATTAGGAGTTACAAACGTGCACAGGGGGAAAGTAGATTTACGGACATTGTACAATATTGCTACAGCAGCGGCAGTCGTCGTCGCAGCAGCTTCTGCAACGAATGCGGTCAACattcacaacaataacaacagccaaACAGTGGTGGTTCATAACAAGCAGCGGCACAATATTGATGTAGATCGAAATGATGGCAATCAAAATCATCACAGTCCAAGTGAAATTGTTGCCAATAATTCCCAGCACAATCTAAAGATGGCTGGTATAGGATTGGAGGCTGGTCCTTCTACAGTTCTTCCTTCTTACACGGCTGCTGGTACATTGTCAGACACATCAACTCCTACGCAAACTCCAGTGCCTCCATCTATGCCACTGTCAACTGCCACGAATTTGTTGTGCGAGGTTCTTGAACCGGAAGTGTCCATTCGCACAATGTACAAATGTTGTAGAAGCCATTTTTTTCAGCAGTCTCAGCGCCAAGCGCAACACCAACATCAGCATTTACAAGTTATACCGCCGCATAATATGACAAATacgtcaacaacaacagcaccatCACCACCAGCATCAATCGCCGATCATGTGTCGACTTGCATGCCAGCCTCATCAACACCCGCAGCACATCATGGCAAGTGTAGTGGTTGTCAAATATCAACTGCTGCTTCAATCCAATTAGCAAATTTAATCGGTACCTCAATGCTCATGCCACAAACAGCAGTGACTGCCGCAACAGTGCAAGATGTCGCATCCAAACGTCACACGCGCGATGAATGTGTTGGCATCCCACCACGCTTTAACTGTGACCTCTGCCCTTCACGTTTCCGACGTAAGTACCACATGGTACGACATTTGACATCGAAACACGGCATTCTTCCGGATATAGCTCAGCAGACGACAAGCAGTAGTGGAAACCGCACCTGTAATGAAAATAACTATGCCGGCTTCAATACCACCAATGATTGTATTGGTCCATTGCCTGAAAATTTGTCACTGAAAAAAAGTCACTATGAGGTAGACAATGTATCACTTAATCGCCATGGAGAAGTTGGTGCCGCTTATGCTCTAAATGTGGGTAAAGCAATGACGACGGATGTTAAGCCAGCATTTGATATAGTTGGAGCTATCGCAACTGTGCCAGCATCAACGACTATAGGCAACAACATCGGCAACAGCAAAATGACAAATTCAATGAAACGCGAAATCGCTCACTCGTTGCCTGGTAGCgttgataataataaaacttcCGAACAAATGGCGACGGACGAAGCTTTGAATACATTTGAAGAAGATTGGAAAATGAAACTAGGCATACAGCTTATATCAAATTCATTACTAAAAGAGCGTCTCTTAAATAGCATGCCATATACTTACAACAATGAGCTGTTACAGAGAAGGGAGCGGGAGCTTGCGGTAGTGAATGTGGTCAATGTAGCTGATTTCTCGTCCGATGTCCACTATCTGGGTTCCATTACAGATAATTATTGGGCAATTTCCATAAAATCCGTGACATCATTGAATAGCATTGCTTGGAAAGAGAAACGTCACAGGCATTCAAATGAATCTACAGGCTATATTACGCCTATCAAAGCTCCAAATAGTGACGGTTGTACTGGAGAAACAGACGATTTAATCCATGATGCGGCACTTTCGACAATTTCTGATCCGCATATATTGAAACATGACAAATCGGAACAAACGGATATCACCCCGGAAGAGTTTGAACTCGATGATTGTCTGCTGGAAAGCAACGATATTGTCATTACTCAGAACAAGGATGGATTCGTGTTGCATGTGAAGAAGTTAGGCAATATTACGACCGCGAAGATTGCCCCAACAGATGAAGATCCAGCAGTCGCAACCAATGTTGCTGATCTTAACGCCCACGCCCACATAACCGATGTGCAACATATTACCGATGTCAAACCTACTCTGACCACTTTGACCACCAGTCAAATAAAGCTACCTTCCTCCGAATGTGagctaataaatttaaagaagatTATACCTGCGACAACAACGATTGCTTCTCATCAGCCTGCAGCGACGATTATTCAACCGCATCAATTTAGTCAGCAACCGCATCCATCGCAACATCATCAACAACATGGTCATGGGTTGGAccaacagcaacaccaacaacagcatcaaatacaacaactgcaatcacATCCTCAAGTACAAAGCATCGTAACGACACATCCCCCACACACCCAGACAATCAACTTGATGGGTCTGCGGAATGTACAAATAGCTGACCAAAAACCAGTTACATCCCGAATTAAGTATTCACgtggaaaaattataactccACAGAGTACAACCGCCGCCAGTGTACAGATCGCAGAGACACATGAGGTGGAGCCGCAACACCATCAACAATTGACCGAAGGTACTAAATATGAGATAAGCGAAATCGATCTAAACAATCCATCAGcttctgcggccatcatcaGTGATTTGGTGAAATATGCCGAGATTGACGATATTGAATTGCCAGACGGTACAAAAATTGGCATAGGGTTTGCACCAACCGAAATTACGGAGCATATACAATCTACAGCCCCGCCTACTACCCAAGTTGGAAGTGTCGATGAAGACTCGCAGCAAGGTGtccaccatcatcatcatcacgtCCAGCATTTGCAAGTAACTCAATTGCATCAAATGCATCCGCAGACACATCATACTCAATTACAGTTACAGGAGCAGGATGATGCCACTACGAGCGTTGAAGCTACTATCCTTCCCGATGGCATTACGCTTCATGAACAGCCGACCATCACAAAGAGTTACACTATACTAACTACACGGCCCATTAAACAAGAAGGATCGGCAAGCGTCGATGGCACCACAACAACCACATATGAACTATCCCTAAGCGATTCATCAATGCATCCTGACGATGGTGAGTCCAAGTATGTGTGCCGTCATTGCGGCAAGAAATACCGTTGGAAATCTACTTTGCGACGACACGAAAACGTCGAATGTGGCGGCAAAGAACCCTGCCACCCTTGCCCGCACTGCTCGTACAAAGCAAAGCAACGTGGAAATCTAGGAGTACATGTGCGAAAGCATCATCCCGATAAACCGGCGTTAGAAAGTAAGCGCGGTCGCAAATAA
Protein Sequence: MEDDQQFCLRWNNHQSTLISVFDTLLENQTLVDCTLAAEGQFLKAHKVVLSACSPFFADLLQQQYDKHPIFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKTAESLQIKGLSDNRSGSTPKTEQHRGLNVHGSGSGGKLSVYTLEQTQPKRPRVGPSPMETTDISGSREGSSSPSRRRKKARRKSAENAMSADVHDNSNSSQINQSSLQPHQQQPQANASLTGVGAITAATSSLPVSASALSTGTSGVLAATGSIVSTQGTTQQMTTNITKKTESVKGASDAMHTENIQAVGVVGTGDEQNVEHVKGEKSNHKQKPSTAGVTGKETADLVIEPKSEYEEEGNEETVEDLTLDDEEMGIEDLDHNAGTSQAGEGSSQGYAPWQHDRSQDELLLAPQETQQRDPQGYFPSFAHSTNSTIIATNSNSNTRPSGATFTRPPLSPPQQQSLTANILIDNKNSNAFQNNPQESHDITIESTESIFSGSIAISSRYQILDNSEENYECPQCYRTYRRHGTLRRHLRQECGKGKSMVCSVCGHRTKRADHLRQHVRKKHPEMAMRSLFRRPTSAAGSSNHGIRTHGFGHRLPPQQRMQQLLQRSLSPPILPYSEIHGQQLQEPLVATKTLPFNTTSTSDAASFMGVDVVDLDAEGDNNGDDNKKSDSDKLDLEHDKVKQQSRADLLGVTNVHRGKVDLRTLYNIATAAAVVVAAASATNAVNIHNNNNSQTVVVHNKQRHNIDVDRNDGNQNHHSPSEIVANNSQHNLKMAGIGLEAGPSTVLPSYTAAGTLSDTSTPTQTPVPPSMPLSTATNLLCEVLEPEVSIRTMYKCCRSHFFQQSQRQAQHQHQHLQVIPPHNMTNTSTTTAPSPPASIADHVSTCMPASSTPAAHHGKCSGCQISTAASIQLANLIGTSMLMPQTAVTAATVQDVASKRHTRDECVGIPPRFNCDLCPSRFRRKYHMVRHLTSKHGILPDIAQQTTSSSGNRTCNENNYAGFNTTNDCIGPLPENLSLKKSHYEVDNVSLNRHGEVGAAYALNVGKAMTTDVKPAFDIVGAIATVPASTTIGNNIGNSKMTNSMKREIAHSLPGSVDNNKTSEQMATDEALNTFEEDWKMKLGIQLISNSLLKERLLNSMPYTYNNELLQRRERELAVVNVVNVADFSSDVHYLGSITDNYWAISIKSVTSLNSIAWKEKRHRHSNESTGYITPIKAPNSDGCTGETDDLIHDAALSTISDPHILKHDKSEQTDITPEEFELDDCLLESNDIVITQNKDGFVLHVKKLGNITTAKIAPTDEDPAVATNVADLNAHAHITDVQHITDVKPTLTTLTTSQIKLPSSECELINLKKIIPATTTIASHQPAATIIQPHQFSQQPHPSQHHQQHGHGLDQQQHQQQHQIQQLQSHPQVQSIVTTHPPHTQTINLMGLRNVQIADQKPVTSRIKYSRGKIITPQSTTAASVQIAETHEVEPQHHQQLTEGTKYEISEIDLNNPSASAAIISDLVKYAEIDDIELPDGTKIGIGFAPTEITEHIQSTAPPTTQVGSVDEDSQQGVHHHHHHVQHLQVTQLHQMHPQTHHTQLQLQEQDDATTSVEATILPDGITLHEQPTITKSYTILTTRPIKQEGSASVDGTTTTTYELSLSDSSMHPDDGESKYVCRHCGKKYRWKSTLRRHENVECGGKEPCHPCPHCSYKAKQRGNLGVHVRKHHPDKPALESKRGRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00081343;
90% Identity: iTF_00081343;
80% Identity: iTF_00081343;