Basic Information

Insect: Anastrepha fraterculus
Gene Symbol: wek
Assembly: GCA_037575425.1
Location: JAYXIM010054367.1:112940-114918[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0019 0.26 13.1 3.3 1 23 260 283 260 283 0.97

2 8 2e-05 0.0028 19.3 1.5 2 23 291 312 290 312 0.97

3 8 0.0003 0.041 15.6 2.1 1 23 321 344 321 344 0.95

4 8 0.00011 0.015 17.0 0.1 1 23 350 372 350 372 0.97

5 8 5e-06 0.00069 21.2 2.8 1 23 378 400 378 400 0.98

6 8 0.00066 0.091 14.5 0.6 1 23 405 427 405 427 0.96

7 8 2.3e-06 0.00032 22.2 2.2 1 23 433 455 433 455 0.97

8 8 0.005 0.69 11.8 2.2 1 23 461 484 461 484 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0019	0.26	13.1	3.3	1	23	260	283	260	283	0.97
2	8	2e-05	0.0028	19.3	1.5	2	23	291	312	290	312	0.97
3	8	0.0003	0.041	15.6	2.1	1	23	321	344	321	344	0.95
4	8	0.00011	0.015	17.0	0.1	1	23	350	372	350	372	0.97
5	8	5e-06	0.00069	21.2	2.8	1	23	378	400	378	400	0.98
6	8	0.00066	0.091	14.5	0.6	1	23	405	427	405	427	0.96
7	8	2.3e-06	0.00032	22.2	2.2	1	23	433	455	433	455	0.97
8	8	0.005	0.69	11.8	2.2	1	23	461	484	461	484	0.96

Sequence Information

Coding Sequence: atggaagctTATGGAGGCTACAATTCCTCTTCCACATCCAAAGATTGGCACTATTGGTGTCGACTTTGCTCGAAGATTGATATacatagtaaaaatatattctatgAACATCAACCACTAATAACTTCTGGTGGAAATACTGACGATAAAAGGAGTACAGTGGCCGTtgcaattggaaaatatttttacgtacaaGTTAAACACGATGATGATCTGCCTCAATTGTTATGCACGGAGTGCACTTCATTGGTGTCAAATATTGCGAATTTCAATGAACGTGTTGCTAAAGTGCAAGAAATGTATACTGCCCTGCAAAGTGGTCACTACAGTAAGGATACAGATTTTCAGTCAATTCGGTTGAAATATGGAATTTTGAAGGAAGATCCAACTCAGTTGTATACGCACCAATATGAAGAAGACTGTTTCACTGAGAATACTGATCAAgcagttatggaaaatttgaataaatttgagATCATATTGAAAAGAGAAAATCCACGAGATGGTATTCAATCCGATGAAGATGAGAGAGATGATAATGAAGATCCTTTTGCCAGCGATTTTGGTGGTGAGACCGCTGAGAACAAGCCTTTTTGTGCAATAAAAGAATGTGATGGAGAAAGTAATGATAGTAAATATCCTCCTGAGGTGCCTTCGAAAGAACaacaaggaaaattaaaaaccagAATAAACATAAGTACAAAAGAAGGTTTAAAAGGGCAAGATAAGTCCGCAAAGTGTCTTATCCGCACCGAGAAAGAGCCAAAAGATGACAAATACTTTTGTGGCGACTGTTCGCTTCATTTTCAACGTCTTGGCAATTATCGTATacatatgaagaaaagacaTGGAATGGCATTAGAACCGTTGACATGTTCCCAATGCTCCAAATCCTTCAAGAATATTTTTGATCTgaatttgcatataaaaacaCATCGACCCCTCTCTGAGAAACGAATATTTCCATGCCCACAATGTGACAgaaaattttcgcaaaaatgtTATGTTGCCAgccatataaaatttgttcatgaaGATATTCGTCCATTTATTTGTGAAGAATGTGGAGAAGGAACACGAACCGAAACTACGCTGCGTGAACATATGCTTATACACACTGACCTGGCACCTTTTGAATGTGAAGTATGTaagaagtttttcaaaaagcaGTCGCGTTTAAAGAGTCATATGCAGATACACAGTTCCAGTAAGCACATCTGCAGAGAATGTGGCTTGCAATTAAATACTCTTGAAACTCTAAATCGTCATATGCTTGTACATTCTGATATTATGCGTCATAAGTGTGATTATTGTGGGCGAGCATTTAAGCGTGCGAAAACGTTAAAGAGCCATTTAATACTCCATAGTGGTCTAAAACCCTATGCATGTGACTTCTGCGATAAAACCTTTGCCAACGGGGCTAATTGTCGTGCgcacaaaagaaaaactcaTCCGGAGGAATTAGCAGCGTTAGAGGCTTCAGGTGAAAAAACATATacgaaaaatataccaaaattggCTGTACTGAAAGCGGtAACAAAATCTGCCGAAAATCTTATCCCAGTTGTCTCCAAACAGAGTGGCAATTTTTCTTTAGGTAGAAAGCCGAAACCTCCACTGGATTATACTGTTGACAGAAAACACTCCAATCCGTTGACAGGAGAAGATGCGTCTGCTGAAACAGTGTTATCGGGgagccaaacattttttaaagaaaacagtTTAGACATGACTAGTCTTACGGAGAGGAATAACATACCATCGTCGTTTTGGTaa
Protein Sequence: MEAYGGYNSSSTSKDWHYWCRLCSKIDIHSKNIFYEHQPLITSGGNTDDKRSTVAVAIGKYFYVQVKHDDDLPQLLCTECTSLVSNIANFNERVAKVQEMYTALQSGHYSKDTDFQSIRLKYGILKEDPTQLYTHQYEEDCFTENTDQAVMENLNKFEIILKRENPRDGIQSDEDERDDNEDPFASDFGGETAENKPFCAIKECDGESNDSKYPPEVPSKEQQGKLKTRINISTKEGLKGQDKSAKCLIRTEKEPKDDKYFCGDCSLHFQRLGNYRIHMKKRHGMALEPLTCSQCSKSFKNIFDLNLHIKTHRPLSEKRIFPCPQCDRKFSQKCYVASHIKFVHEDIRPFICEECGEGTRTETTLREHMLIHTDLAPFECEVCKKFFKKQSRLKSHMQIHSSSKHICRECGLQLNTLETLNRHMLVHSDIMRHKCDYCGRAFKRAKTLKSHLILHSGLKPYACDFCDKTFANGANCRAHKRKTHPEELAALEASGEKTYTKNIPKLAVLKAVTKSAENLIPVVSKQSGNFSLGRKPKPPLDYTVDRKHSNPLTGEDASAETVLSGSQTFFKENSLDMTSLTERNNIPSSFW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00083406;
90% Identity: iTF_00083306; iTF_00083300; iTF_00083310; iTF_00081565;
80% Identity: -