Basic Information

Insect: Anastrepha fraterculus
Gene Symbol: wek
Assembly: GCA_037575425.1
Location: JAYXIM010051641.1:5456-17602[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.0035 0.49 12.2 4.2 1 23 297 320 297 320 0.97

2 20 2.1e-05 0.0029 19.2 4.0 2 23 330 351 329 351 0.97

3 20 0.0005 0.07 14.9 0.7 1 23 360 383 360 383 0.95

4 20 6.8e-05 0.0093 17.6 0.1 1 23 389 411 389 411 0.97

5 20 2.9e-06 0.00039 22.0 0.8 1 23 417 439 417 439 0.98

6 20 0.001 0.14 13.9 0.9 1 23 444 466 444 466 0.96

7 20 5.2e-06 0.00072 21.1 2.2 1 23 472 494 472 494 0.97

8 20 0.049 6.8 8.6 3.9 1 23 500 523 500 523 0.97

9 20 0.0055 0.77 11.6 4.0 1 23 908 931 908 931 0.97

10 20 0.0069 0.95 11.3 4.0 2 23 939 960 938 960 0.97

11 20 0.00065 0.09 14.5 0.2 2 23 970 992 969 992 0.94

12 20 0.00035 0.048 15.4 0.1 1 23 998 1020 998 1020 0.97

13 20 3.4e-06 0.00047 21.7 3.4 1 23 1026 1048 1026 1048 0.98

14 20 0.001 0.14 13.9 0.9 1 23 1053 1075 1053 1075 0.96

15 20 7.4e-06 0.001 20.7 2.2 1 23 1081 1103 1081 1103 0.97

16 20 0.048 6.6 8.7 3.8 1 23 1109 1132 1109 1132 0.97

17 20 7.8e-06 0.0011 20.6 2.3 1 23 1441 1463 1441 1463 0.98

18 20 0.0027 0.38 12.6 0.5 1 23 1468 1490 1468 1490 0.96

19 20 5.2e-06 0.00072 21.1 2.2 1 23 1496 1518 1496 1518 0.97

20 20 0.084 12 7.9 4.1 1 23 1524 1547 1524 1547 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.0035	0.49	12.2	4.2	1	23	297	320	297	320	0.97
2	20	2.1e-05	0.0029	19.2	4.0	2	23	330	351	329	351	0.97
3	20	0.0005	0.07	14.9	0.7	1	23	360	383	360	383	0.95
4	20	6.8e-05	0.0093	17.6	0.1	1	23	389	411	389	411	0.97
5	20	2.9e-06	0.00039	22.0	0.8	1	23	417	439	417	439	0.98
6	20	0.001	0.14	13.9	0.9	1	23	444	466	444	466	0.96
7	20	5.2e-06	0.00072	21.1	2.2	1	23	472	494	472	494	0.97
8	20	0.049	6.8	8.6	3.9	1	23	500	523	500	523	0.97
9	20	0.0055	0.77	11.6	4.0	1	23	908	931	908	931	0.97
10	20	0.0069	0.95	11.3	4.0	2	23	939	960	938	960	0.97
11	20	0.00065	0.09	14.5	0.2	2	23	970	992	969	992	0.94
12	20	0.00035	0.048	15.4	0.1	1	23	998	1020	998	1020	0.97
13	20	3.4e-06	0.00047	21.7	3.4	1	23	1026	1048	1026	1048	0.98
14	20	0.001	0.14	13.9	0.9	1	23	1053	1075	1053	1075	0.96
15	20	7.4e-06	0.001	20.7	2.2	1	23	1081	1103	1081	1103	0.97
16	20	0.048	6.6	8.7	3.8	1	23	1109	1132	1109	1132	0.97
17	20	7.8e-06	0.0011	20.6	2.3	1	23	1441	1463	1441	1463	0.98
18	20	0.0027	0.38	12.6	0.5	1	23	1468	1490	1468	1490	0.96
19	20	5.2e-06	0.00072	21.1	2.2	1	23	1496	1518	1496	1518	0.97
20	20	0.084	12	7.9	4.1	1	23	1524	1547	1524	1547	0.96

Sequence Information

Coding Sequence: ATGCAGACAGGAAACGCATCAATCGGCGGAAAAGACTACAACTCCACTTCTACCTCCGCATCCGCATCCGCAGATTGGCACTATTGGTGTCGACTTTGCGCAAAGATTGATACACacagtgaaaatattttctatgaacaTCAACCACAAACAACTTACTCGGGGGGCAAAAGTGACGATAATAGATGTACAATGGCCGTAGcaataggaaaatatttttacgtacAAATAAAACACGATGACGATCTGCCCAAACTGTTATGCACAGAGTGCATTTCATTGGTGACAACCCTTCTAGATTTCAATGAACGTGTTGTAAAAGTGCAAGAAATGTATGCTGAACTGCAAAGTGCTCAATTCAGTAACGATACAGATTTTCAGTCTATTCGACTAAAATATGGAATTCTGAAGGAAGATCCAGCTCAATTATACAAGCACCAACATGAAGAAGATTGTTTTACTGAAAAGATTGATGAAACAAGTGTGGCAAACATGCacaattttgaaatcaaattaataacgGAAATTTCAACCGATTGTATGCAAACCAATGAAGTTAGTCATTCACTTGAATTTGAAGGCACGGAAGGTGAAGATCCATTTGCCAGCGGAGTTGTCGTTGAGACCTCTGAAAACCAGACTCTTCGTGCAATAAAAGAATGTGATGGAGAAAGTAATGATGGTAAATTATCTGATTTCATACCTTTGAATGCACAGAATAAGTTATTAAAAaccgaaataaaaacaaatgaaaagggAGGAGCTTCAAAAAAAGATAATGAATTGAAGTTAATGGATACTAATCGTAAACGATCTCATAAAAGTAGTTTTGGTATAAAGTTAGAAAAGTTTATTACTGGCTCCGAGGGAAAGTCAACTGATGACAAATACTTTTGTAGCACCTGTTCCCTTCATTTTCAACGTCCTGGCAATTTTCGTGTgcatatgaagaaaagacaTGACATCGTATATGAATTAGATCCTTTGACATGTCCTCAATgtcaaaaatctttcaaaacagAGTTCAAACTAAACCATCACATAAAAACGCATCGGCCACTGTCGGATAAGCGAATATTTCCATGCCCACAATGTGATCGAAAATTTCAGACAAAAGATTCTGTAAGCACacatataaaatttgttcatgaaGATATTCGTCCATTTATTTGTGAAGAATGTGGTAAAGGTACACGAACGGAAACAACACTACGAGAACATATGCTTATACACACTGACCTGGCACCTTTTGAATGTGAAATATGTAAGAAAGGTTTCAAAAATCAGGCGCGTTTAAAGAATCATATGCAGATACACAGTTCCAGTAAACACATCTGCAGAGAATGTGGCTTACAATTAAATACTCGTGAAACTCTAAATCGTCATATGCTTGTACATTCTGATATTATGCGTCATAAGTGTGATTATTGTGGGCGAGCATTTAAACGAGCCAAAACGCTGAAGAATCATTTAATACTCCATAGTGGTCTAAAGCCCTATACATGTGACTTCTGTGACAGAACTTTTGCAACTGGGGCCAATTGCCGGACTCACAAAAGAAAATCACATCCGGAAGAATTAGCTACATTAGAGGCTTCAGGAGAAAAAACTTACACGAAAAATATACCCAGATTGTCTGTGTTAAAAACagtAACGCAATCTGCCGAAAATCTAATTCCTGTTGTCTCCAAACAGAATGATGACCTTTTATTAGGAAGGAAATTGAAACTTCCGTCCGATTGTGCTATTGGTGCCAATCACTCCAGTTCCTTGACAACGATAAATTCATCGGCTGAAACAGTACTTTCAAGCACAGTGTACACAAACGGAGAGCAAAATATGCAGACAGGAAACGCATCAATCGGCGGAAAAGACTACAACTCCACTTCTACCTCCGCATCCGCATCCGCAGATTGGCACTATTGGTGCCGACTTTGCGCAAAGATTGATACACacagtgaaaatattttctatgaacaTCAACCACAAATAACTTACTCGGGGGGCAAAAGTGACGATAATAGATGTACAATGGCCGTAGcaataggaaaatatttttgcgtacaAATAAAACACGATGACGATCTGCCCAAACTGTTATGCACAGAGTGCATTTCATTGGTAACAACCCTTCTAGATTTCAATGAACGTGTTGTAAAAGTGCAAGAAATGTATGCTGAACTACAAAGTGCTCAATTCATTACCGATACAGATTTTCAGTCTATTCGACTAAAATATGGAATTTTGAAGGAAGATCCAGCTATACAGCACCAACATGAAGAAGAGTGTTTTACTGAGAAAATTGATCAAGCAAGTGTGGCAAACATGCACAAAtttgaaatcaaattaataacgGAAGTCTCAAGCGATGGTATCCAAACAGATGAAGTTAGTCATTCACTTGAATTTGAAGGCACGGAAGGTGAAGATCCATTTGCCAGCGGAGTTGTCGTTGAGACCTCTGAAAACCAGACTCTTCGTGCAATAAAAGAATGTGATCGAGAAAGTAATGATGGTAAATTATCTGATTTCATACCTCTGAATGCACAGAATAAGTTATTAAAAACCGAAATAAACACAAATGACAAGAGAGGATCGTCAAAGAAGGATAAGAAATTGAAGTTAATTGATACTAATCTTAAACGATCTTACAAAAGTAGTTTTGACAAAAAGGTAGAAAAGTGTATTACTGGCTCCGAGGAAAAGTCAACTGATGACAAATACTTTTGTAGCACCTGCTCTCTTCATTTCCAACGTCCTGGCAATTATCGTATacatatgaagaaaagacaTGGAATGGCACTAGAACCTTTGACATGCTCTCAATGTCATAAATCTTTCAAGACAGTATTCGAattgaattttcatataaaaacacATCGTCCACTATCAGAGAAACGAATTCTTCCATGCCCACAATGTGACCGAAAATTTCAGACAAAAGGTTCTGTAGCCAGGCATATAAAGTTTGTTCATGAAGATATTCGTCCATTTATTTGTGAAGAATGTGGAGAAGGAACACGAACCGAAACAACACTACGAGAACATATGCTTATACACACTGACCTGGCACCTTTTGAATGTGAAATATGTaagaaatgtttcaaaaatcaGGCGCGTTTAAAGAATCATATGCAGATACACAGTTCCAGTAAACACATCTGCAGAGAATGTGGCTTACAATTAAATACTCGTGAAACTCTAAATCGACATATGCTAGTACATTCTGATATTATGCGTCATAAGTGTGATTATTGTGGGCGAGCATTTAAGCGTGCGAAAACGCTAAAAAGCCATTTAATACTCCATAGTGGTCTAAAGCCCTATACATGTGACTTCTGTGACAGAACCTTTGCTAATGGGGCCAATTGTCGTACTCACAAAAGGAAATCACATCCGGAAGAATTAGCGGCATTAGAGGCTTCAGGAGAAAAAACATACACGAAAAATATACCCAGACTGGCCGCATTAAAAACAGTaACAAAGCCTATTTGTACTGTTGGCACAAAGGACTCCAATTCGGTGATAAAGATAGATGGATCTGCTGAAACAGGACTTTCTGAAAGTAAAACAATGTTTAATACTAATGATTCAGACACAGGCAACTTTCCAAATGGAATGAATATAGAAGAAGGGCAAGACATGCAAACGACAACGACATCAGTCGGCGAAAAAAGCTTCAACACCACCTCAGCATTCACAGATTGGCATTATTGGTGTCGACTTTGCGCAAAGATTGATACACacagtgaaaatattttctatgaacaTCAACCACAAATAACTTACTCGGGGGGCAAAAGTGACGATAATAGATGTACAATGGCCGTAGcaataggaaaatatttttgcgtacaAATAAAACACGATGACGATTTGCCCAAATTATTATGCACAGAGTGCATTTCATTGGTGACAACCCTTCTAGATTTTAATCAACGTGTTGATAAAGTGCAAGAAATGTATGCTGAACTGCAAAGTGCTCAATTCAGTAACGATACAGATTTCCAGTCTATTCGACTAAAATATGGAATTTTGAAGGAAGATCCAGCTCAATTATACAAGCACCAACATCAAGAAGATTATTTTACTGAGAGGATTGATCAAACAAGTATGGCTAACATGCACAATTTTGAAGTTAAACTAATAAAAGAAATCTCGAGGGATGGCATCCAAGACGATGAAGTTGACTATGCCAAAGAACCTGAGGGAGCTGGAAGTGATCCTTTTGTCAGCAAAATTGGCGTAGAGACCGCTGAGGGCCAGACATTTTGTGCAATAAAAGAATGTGATGAAGAAAGTAGTGACGACCTTGCACCTTTTGAGTGCGAAATATGTAAGAAAGGTTTTAAAAATCGTACCCGCCTTAAGAAACATATGGACACGCACAGTTCTAATAAACACATCTGCAGCGAGTGTGGTTTAAAACTAAATTCTCGTGTGACTTTAAACTTACATATGCTCGTACATTCTGATGTTATGCGCCACAAATGTGACTACTGTGGGCGGGCTTTCAAACGAGCCAAAACGctgaaaaatcatttaatacTCCATAGTGGACTAAAACCTTATTCATGCGATTTCTGCGATAAAACTTTTGCCAATGGGGCTAATTGTCgtacgcacaaaaaaaaaactcatccgGAGGAATTAGCAGCGTTAGAGGCTTCAGGcgaaaaaacacatacaaaaaatataccaaaattggCTGTACTGAAAACtgtAACAAAATCAGCCGAAAATCTTATCCCAGTTGTCTCCAAACAgagtggcaatttttttttaggtagaAAGCCGAAACCTCCACTAGATTATACTGTTGACAGAAAACACTCCAATTCGTTGACAGGAGTAGATGCGTCTGCTGAAACAGTGTTATCGGGGAGCCaaccattttttaaagaaaacagtTTAGACATGACTAGTCTTACGGAGAGGAATAACATACCATCGTCGTTTTGGTaa
Protein Sequence: MQTGNASIGGKDYNSTSTSASASADWHYWCRLCAKIDTHSENIFYEHQPQTTYSGGKSDDNRCTMAVAIGKYFYVQIKHDDDLPKLLCTECISLVTTLLDFNERVVKVQEMYAELQSAQFSNDTDFQSIRLKYGILKEDPAQLYKHQHEEDCFTEKIDETSVANMHNFEIKLITEISTDCMQTNEVSHSLEFEGTEGEDPFASGVVVETSENQTLRAIKECDGESNDGKLSDFIPLNAQNKLLKTEIKTNEKGGASKKDNELKLMDTNRKRSHKSSFGIKLEKFITGSEGKSTDDKYFCSTCSLHFQRPGNFRVHMKKRHDIVYELDPLTCPQCQKSFKTEFKLNHHIKTHRPLSDKRIFPCPQCDRKFQTKDSVSTHIKFVHEDIRPFICEECGKGTRTETTLREHMLIHTDLAPFECEICKKGFKNQARLKNHMQIHSSSKHICRECGLQLNTRETLNRHMLVHSDIMRHKCDYCGRAFKRAKTLKNHLILHSGLKPYTCDFCDRTFATGANCRTHKRKSHPEELATLEASGEKTYTKNIPRLSVLKTVTQSAENLIPVVSKQNDDLLLGRKLKLPSDCAIGANHSSSLTTINSSAETVLSSTVYTNGEQNMQTGNASIGGKDYNSTSTSASASADWHYWCRLCAKIDTHSENIFYEHQPQITYSGGKSDDNRCTMAVAIGKYFCVQIKHDDDLPKLLCTECISLVTTLLDFNERVVKVQEMYAELQSAQFITDTDFQSIRLKYGILKEDPAIQHQHEEECFTEKIDQASVANMHKFEIKLITEVSSDGIQTDEVSHSLEFEGTEGEDPFASGVVVETSENQTLRAIKECDRESNDGKLSDFIPLNAQNKLLKTEINTNDKRGSSKKDKKLKLIDTNLKRSYKSSFDKKVEKCITGSEEKSTDDKYFCSTCSLHFQRPGNYRIHMKKRHGMALEPLTCSQCHKSFKTVFELNFHIKTHRPLSEKRILPCPQCDRKFQTKGSVARHIKFVHEDIRPFICEECGEGTRTETTLREHMLIHTDLAPFECEICKKCFKNQARLKNHMQIHSSSKHICRECGLQLNTRETLNRHMLVHSDIMRHKCDYCGRAFKRAKTLKSHLILHSGLKPYTCDFCDRTFANGANCRTHKRKSHPEELAALEASGEKTYTKNIPRLAALKTVTKPICTVGTKDSNSVIKIDGSAETGLSESKTMFNTNDSDTGNFPNGMNIEEGQDMQTTTTSVGEKSFNTTSAFTDWHYWCRLCAKIDTHSENIFYEHQPQITYSGGKSDDNRCTMAVAIGKYFCVQIKHDDDLPKLLCTECISLVTTLLDFNQRVDKVQEMYAELQSAQFSNDTDFQSIRLKYGILKEDPAQLYKHQHQEDYFTERIDQTSMANMHNFEVKLIKEISRDGIQDDEVDYAKEPEGAGSDPFVSKIGVETAEGQTFCAIKECDEESSDDLAPFECEICKKGFKNRTRLKKHMDTHSSNKHICSECGLKLNSRVTLNLHMLVHSDVMRHKCDYCGRAFKRAKTLKNHLILHSGLKPYSCDFCDKTFANGANCRTHKKKTHPEELAALEASGEKTHTKNIPKLAVLKTVTKSAENLIPVVSKQSGNFFLGRKPKPPLDYTVDRKHSNSLTGVDASAETVLSGSQPFFKENSLDMTSLTERNNIPSSFW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -