Basic Information

Gene Symbol
-
Assembly
GCA_017163975.1
Location
JAFFSR010000218.1:349242-350222[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00017 0.059 16.4 3.7 2 23 67 89 66 89 0.88
2 9 1.6e-05 0.0054 19.7 0.4 1 23 95 118 95 118 0.98
3 9 6.4e-05 0.022 17.8 0.9 2 23 125 147 124 147 0.90
4 9 2.7e-06 0.00093 22.1 1.5 2 23 154 176 153 176 0.90
5 9 7e-08 2.4e-05 27.1 0.6 2 23 183 205 182 205 0.96
6 9 2.4e-06 0.0008 22.3 1.0 2 23 212 234 211 234 0.96
7 9 1.7e-06 0.00057 22.7 3.4 2 23 241 263 241 263 0.96
8 9 4e-06 0.0014 21.5 0.9 2 23 270 292 269 292 0.96
9 9 4.4e-07 0.00015 24.6 4.4 2 23 299 321 298 321 0.96

Sequence Information

Coding Sequence
ATGCAACTCTCAGCGCCAATTATTAAACATGAAGAATCAATACATATTAAAGATGAAATGCATAACATATCAGATTCAACGTCTAGAACACCTGACCAGAAAACTAGTTTGATTTCTATTAAAGATGAAAGATACGGTGAATTGGTGAATGACAAAAGTTGTCCTCTTGATCAACGTCCAactgaattagaaaaaataagttgcGATATTTGTGGCAAATGCTTTTCGAGTCGAAGAAAGCTCAATATCCATTGCAGGGAAGTACACGCAAAAATTCGAAAGTATGTTTGTAATTTGTGTAATAAAGGATTTGTCCGTAACTTTGTATTAAAAGTGCACGAACGTACGATACATCGAAAGATCCGAGACTGGAAGTGCATTCATTGCGGTAAATCATTTGGTACGAAATCTAATTTAGAATATCATGAAAAGGCAATACATTTGAACATTCGAGATTGGAAGTGTACGCATTGCGGTAAAGCTTTTAATACTAAACAGCTTTTAAAACGTCATGAAAGTGCAGTACACATGAAAATTCAAGATTGGAAGTGCCCTGATTGCGATAAAGCTTTTAATACTAAACAGAATTTAAAACGTCATGAAAGTACTGTACACTTGAAAATCCGAGACTGGGAGTGCACAAATTGCAAAAAGTCTTTTGTcacgaaaaattatttaaaagtgcACGAACGCACGGTACATCTAAAGATTCGAGATCGGAAGTGCACTCATTGCGATAAAGCTTTTAGTACTAAACAGGATTTAAAACGTCATGAAAGTACTGTACACTTGAAAATCCGAGACTGGGAGTGCACAAATTGCAAAAAGTCTTTTGTcacgaaaaattatttaaaagtgcACGAACGCATGGTACATCTTATGATTCGAGATTGGAAGTGTACACATTGTGACAAATATTTTAGTACTAAGTCGAGTTTGAAACGTCACGAGAGAAAAGCACACTTAGAAAAGCCAAAGTAG
Protein Sequence
MQLSAPIIKHEESIHIKDEMHNISDSTSRTPDQKTSLISIKDERYGELVNDKSCPLDQRPTELEKISCDICGKCFSSRRKLNIHCREVHAKIRKYVCNLCNKGFVRNFVLKVHERTIHRKIRDWKCIHCGKSFGTKSNLEYHEKAIHLNIRDWKCTHCGKAFNTKQLLKRHESAVHMKIQDWKCPDCDKAFNTKQNLKRHESTVHLKIRDWECTNCKKSFVTKNYLKVHERTVHLKIRDRKCTHCDKAFSTKQDLKRHESTVHLKIRDWECTNCKKSFVTKNYLKVHERMVHLMIRDWKCTHCDKYFSTKSSLKRHERKAHLEKPK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-