Basic Information

Insect: Anaspis maculata
Gene Symbol: topi
Assembly: GCA_949128115.1
Location: OX421961.1:106271464-106286856[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.025 1.4 10.8 1.9 2 21 103 122 102 123 0.94

2 14 2.1e-06 0.00012 23.6 0.3 1 23 148 170 148 170 0.97

3 14 0.062 3.4 9.5 3.3 2 23 177 198 177 198 0.95

4 14 0.89 49 5.9 1.5 2 13 217 228 216 235 0.87

5 14 0.0042 0.23 13.2 0.5 2 23 293 314 292 314 0.97

6 14 3.3 1.8e+02 4.1 0.1 1 19 320 338 320 341 0.81

7 14 1.1 62 5.6 2.8 2 21 357 376 356 380 0.83

8 14 0.83 46 6.0 0.1 1 23 511 534 511 534 0.97

9 14 0.11 6.3 8.7 0.1 2 23 539 560 538 560 0.95

10 14 2.1e-06 0.00012 23.6 2.4 1 23 566 588 566 588 0.98

11 14 0.061 3.4 9.5 0.2 1 23 594 619 594 619 0.96

12 14 0.088 4.9 9.0 2.7 1 23 625 647 625 647 0.86

13 14 0.0002 0.011 17.4 0.5 3 23 655 675 653 675 0.97

14 14 0.0011 0.061 15.0 1.7 1 23 681 704 681 704 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.025	1.4	10.8	1.9	2	21	103	122	102	123	0.94
2	14	2.1e-06	0.00012	23.6	0.3	1	23	148	170	148	170	0.97
3	14	0.062	3.4	9.5	3.3	2	23	177	198	177	198	0.95
4	14	0.89	49	5.9	1.5	2	13	217	228	216	235	0.87
5	14	0.0042	0.23	13.2	0.5	2	23	293	314	292	314	0.97
6	14	3.3	1.8e+02	4.1	0.1	1	19	320	338	320	341	0.81
7	14	1.1	62	5.6	2.8	2	21	357	376	356	380	0.83
8	14	0.83	46	6.0	0.1	1	23	511	534	511	534	0.97
9	14	0.11	6.3	8.7	0.1	2	23	539	560	538	560	0.95
10	14	2.1e-06	0.00012	23.6	2.4	1	23	566	588	566	588	0.98
11	14	0.061	3.4	9.5	0.2	1	23	594	619	594	619	0.96
12	14	0.088	4.9	9.0	2.7	1	23	625	647	625	647	0.86
13	14	0.0002	0.011	17.4	0.5	3	23	655	675	653	675	0.97
14	14	0.0011	0.061	15.0	1.7	1	23	681	704	681	704	0.98

Sequence Information

Coding Sequence: ATGAACACATTTGATGataaatatttttcaataatcaaCGCGCATTATCTTTTCCCCGACGGGAAGCTGTCCTCCACGAGGTACGAAGTTGATTTTGTCACGCACCAGCTAGTTTCGAAAAAACCGGTCATTGATATTCCCGATGTGAGTTTCGACTTTGCCGCTTCTCTGGACTCGGCCACCGGGCTGAATTTGGGAGTCTCGGCCGACCAAGGACAAGGAGCCGTGATGATCTACGAAGTGGCAAGTACCCTCGATCTGGACTTCAACAAGAGGAAGTACAAGTTCAACATACCCAACATGATCCGATGTCAGAATTGCGAAACGAACTACCCAACGAAATACCAATACCAGAGGCACCAGTGTGAGTTCAATGCCGAAAAAGTCGTCCTAAAACCTGACGCAGACTTCTCCGACACAGACAAAGGCAAACGCGTCAAATACGATTGCGGCACTTGCGGCAAACAATTTGTCAGTGAGAGCAACCTAGAACGCCACCAACTGAGCCACGTAAGCTCCAAAGACAACACCTGCGAACACTGCAAAAAACAATTCGTCAGTGAGAACCGCCTGAGGATCCACAAGGAGAACCACTGCAAAAAATCCGGCGACATCTCCAAGTTCTATCGCAGCGACGTCACCGTATGGAGATGCAAGAAATGCCACGAAGTGTTCTCGTCGTGCGCGACGGCCAGCTTCCACATGGAGCACTGCGACCAGCAGCTCAACCCGGAACGTTTCGCCATCCTCAGCACGGAAGACATCAAGAAGGAACCCGGATCTCAACAGCAGGCGACGCCAGAAACAAATGCCGAAGGTATCCCCGCCGCCGGCGACAGCAAAGTCGTCGATAAGATCTCGACTGAAATCTTGCTGCAGTGCGAATTCTGCAACCGCACGTACGCCGATAAGCAAGTCTTGCTTGGGCACCAGAAAACACACAAAACCGACAAGAATTACGAATGCGTCGTCTGCAGGGAGTCGTTCGATTCATACATCACGGCGTCTCAACATTGGCTCAAGAAATGTTCGGAAAAATCGAACCTGTTCTATCTGCCCAAGCTGACGTACTGCGAATTTTGCGACAGGACGTTCAAATCGCACGAGATTTTGTATACGCACAAGATCAAGAAGAGGCATTACACGCCGAAGTTCCACACGGATGTTGCGGAAGTTGTCGTGGAGAAACTGAACAATCACGACAAGGACATCAAGAACGAAGAGGTAATCGACAAGCTCGTAGAAGACGTCCTCATAGCTCTCGAAATTCCACTCAAGAAGCGCACcgtaaacaaaaaatcggcgccCTCAGCAGCACTGACCGACGAAGATGTGGTCAACAGCAGCGGCAGCAGCAAAGAAAACGTCGATCCAAGCGAAATTACCGTCAAAACCGAACCAAGCCACTCCAACGAAGACGACTTTCAGGAAAACGACACGTTCGAAAAAAGGAAGCGTGGCAGAAAACGAAAGCTGCCCAAGCAGGCGCTCAAAATCAAAAAGCCTCTCGCGCTGGAAGACGGCTACAAGTTCCAATGCGAACGATGCGTTCAAGTTTGGGAAACGATATCCGCTCTGGAGGAGCACCGGAAAACTGAACACGCGGCCAGCCTCATGTGCGATGAGTGTGGGCAGGTCCTGCACAGCGCCAGGGCTCTGTTGATCCACAGCAGGGCGCACAAGAGTTTGAAGCCGTACGTGTGCGAGACTTGCGGCAGGAGTTACTCGCAGACTTCGCATTTGTGGCAGCATATGCGGTTTCACCAAGGGATCAAACCGTTTGCCTGTCCCCACGAGGGTTGCGAAGCTCGATACACAATCCGACCCGACTTGAAAGACCACATCCGGAAGGTACACACCAGGGAGCGTCCCTTCAAGTGCAACGTATGCGGAAAGTGCTTCCTGACCGGCTCTGTGTACTACCAACATCGCCTGATTCACACGGAAGATCGACGCTACGGATGTGACATGTGCGAAAAACGCTTCTTCAGAGCTGACGCGTTAAACAACCACAAACGGATCCACACCAACGAAAGACCTTACCCGTGCTTCGTTTGCGGCCGCCTGTTTCGACAGAAAGGCGACCGCAACAAACATTTCCGCACGCAACATCCTGACGCCATCGACACTTAG
Protein Sequence: MNTFDDKYFSIINAHYLFPDGKLSSTRYEVDFVTHQLVSKKPVIDIPDVSFDFAASLDSATGLNLGVSADQGQGAVMIYEVASTLDLDFNKRKYKFNIPNMIRCQNCETNYPTKYQYQRHQCEFNAEKVVLKPDADFSDTDKGKRVKYDCGTCGKQFVSESNLERHQLSHVSSKDNTCEHCKKQFVSENRLRIHKENHCKKSGDISKFYRSDVTVWRCKKCHEVFSSCATASFHMEHCDQQLNPERFAILSTEDIKKEPGSQQQATPETNAEGIPAAGDSKVVDKISTEILLQCEFCNRTYADKQVLLGHQKTHKTDKNYECVVCRESFDSYITASQHWLKKCSEKSNLFYLPKLTYCEFCDRTFKSHEILYTHKIKKRHYTPKFHTDVAEVVVEKLNNHDKDIKNEEVIDKLVEDVLIALEIPLKKRTVNKKSAPSAALTDEDVVNSSGSSKENVDPSEITVKTEPSHSNEDDFQENDTFEKRKRGRKRKLPKQALKIKKPLALEDGYKFQCERCVQVWETISALEEHRKTEHAASLMCDECGQVLHSARALLIHSRAHKSLKPYVCETCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCGKCFLTGSVYYQHRLIHTEDRRYGCDMCEKRFFRADALNNHKRIHTNERPYPCFVCGRLFRQKGDRNKHFRTQHPDAIDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -