Basic Information

Insect: Anaspis maculata
Gene Symbol: ZEB2
Assembly: GCA_949128115.1
Location: OX421963.1:30971510-30991131[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 34 0.051 2.8 9.8 2.6 1 20 14 33 14 35 0.94

2 34 0.01 0.56 12.0 5.1 1 23 41 63 41 63 0.97

3 34 2.5 1.4e+02 4.5 1.0 1 20 183 202 183 204 0.94

4 34 0.25 14 7.6 1.3 2 23 211 233 211 233 0.94

5 34 0.061 3.4 9.5 1.5 3 23 239 259 238 259 0.97

6 34 0.017 0.92 11.3 6.1 1 23 265 288 265 288 0.96

7 34 1.2 67 5.4 0.4 1 12 293 304 293 307 0.88

8 34 6.4e-05 0.0035 18.9 3.1 2 23 321 342 320 342 0.96

9 34 0.0002 0.011 17.3 4.0 1 23 348 370 348 370 0.97

10 34 0.0029 0.16 13.7 2.2 1 23 378 400 378 400 0.99

11 34 0.032 1.8 10.4 0.2 3 23 408 429 406 429 0.94

12 34 0.00077 0.042 15.5 0.9 1 23 434 456 434 456 0.96

13 34 0.16 8.9 8.2 4.9 1 23 466 489 466 489 0.92

14 34 0.0021 0.11 14.2 0.3 1 23 496 518 496 518 0.97

15 34 1.5e-05 0.0008 20.9 0.2 2 23 525 546 524 546 0.97

16 34 2.4e-05 0.0013 20.2 0.8 1 23 552 574 552 574 0.97

17 34 0.003 0.17 13.7 0.6 1 23 670 693 670 693 0.97

18 34 0.00018 0.01 17.5 1.7 3 23 701 721 700 721 0.98

19 34 0.00011 0.0063 18.1 3.6 1 21 727 747 727 749 0.94

20 34 2.3e-06 0.00013 23.5 0.4 1 23 755 777 755 777 0.98

21 34 0.23 12 7.8 0.6 1 21 783 803 783 804 0.89

22 34 0.25 14 7.6 0.0 1 19 900 918 900 920 0.95

23 34 0.001 0.056 15.1 2.4 1 23 929 951 929 951 0.96

24 34 3.2 1.8e+02 4.1 1.4 1 23 994 1017 994 1017 0.89

25 34 0.0047 0.26 13.0 1.0 3 23 1025 1045 1024 1045 0.97

26 34 5.4e-06 0.0003 22.3 0.6 1 23 1051 1073 1051 1073 0.95

27 34 0.001 0.057 15.1 2.6 1 23 1079 1102 1079 1102 0.96

28 34 5.1 2.8e+02 3.5 0.3 1 19 1241 1259 1241 1262 0.92

29 34 0.12 6.8 8.6 2.5 2 20 1284 1302 1283 1304 0.92

30 34 0.011 0.59 11.9 0.4 3 23 1325 1346 1324 1346 0.96

31 34 0.12 6.6 8.6 4.6 1 23 1387 1409 1387 1409 0.98

32 34 0.096 5.3 8.9 0.6 3 23 1635 1656 1635 1656 0.96

33 34 0.0031 0.17 13.6 3.4 1 23 1697 1719 1697 1719 0.98

34 34 1.2 69 5.4 0.7 1 21 1725 1745 1725 1746 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	34	0.051	2.8	9.8	2.6	1	20	14	33	14	35	0.94
2	34	0.01	0.56	12.0	5.1	1	23	41	63	41	63	0.97
3	34	2.5	1.4e+02	4.5	1.0	1	20	183	202	183	204	0.94
4	34	0.25	14	7.6	1.3	2	23	211	233	211	233	0.94
5	34	0.061	3.4	9.5	1.5	3	23	239	259	238	259	0.97
6	34	0.017	0.92	11.3	6.1	1	23	265	288	265	288	0.96
7	34	1.2	67	5.4	0.4	1	12	293	304	293	307	0.88
8	34	6.4e-05	0.0035	18.9	3.1	2	23	321	342	320	342	0.96
9	34	0.0002	0.011	17.3	4.0	1	23	348	370	348	370	0.97
10	34	0.0029	0.16	13.7	2.2	1	23	378	400	378	400	0.99
11	34	0.032	1.8	10.4	0.2	3	23	408	429	406	429	0.94
12	34	0.00077	0.042	15.5	0.9	1	23	434	456	434	456	0.96
13	34	0.16	8.9	8.2	4.9	1	23	466	489	466	489	0.92
14	34	0.0021	0.11	14.2	0.3	1	23	496	518	496	518	0.97
15	34	1.5e-05	0.0008	20.9	0.2	2	23	525	546	524	546	0.97
16	34	2.4e-05	0.0013	20.2	0.8	1	23	552	574	552	574	0.97
17	34	0.003	0.17	13.7	0.6	1	23	670	693	670	693	0.97
18	34	0.00018	0.01	17.5	1.7	3	23	701	721	700	721	0.98
19	34	0.00011	0.0063	18.1	3.6	1	21	727	747	727	749	0.94
20	34	2.3e-06	0.00013	23.5	0.4	1	23	755	777	755	777	0.98
21	34	0.23	12	7.8	0.6	1	21	783	803	783	804	0.89
22	34	0.25	14	7.6	0.0	1	19	900	918	900	920	0.95
23	34	0.001	0.056	15.1	2.4	1	23	929	951	929	951	0.96
24	34	3.2	1.8e+02	4.1	1.4	1	23	994	1017	994	1017	0.89
25	34	0.0047	0.26	13.0	1.0	3	23	1025	1045	1024	1045	0.97
26	34	5.4e-06	0.0003	22.3	0.6	1	23	1051	1073	1051	1073	0.95
27	34	0.001	0.057	15.1	2.6	1	23	1079	1102	1079	1102	0.96
28	34	5.1	2.8e+02	3.5	0.3	1	19	1241	1259	1241	1262	0.92
29	34	0.12	6.8	8.6	2.5	2	20	1284	1302	1283	1304	0.92
30	34	0.011	0.59	11.9	0.4	3	23	1325	1346	1324	1346	0.96
31	34	0.12	6.6	8.6	4.6	1	23	1387	1409	1387	1409	0.98
32	34	0.096	5.3	8.9	0.6	3	23	1635	1656	1635	1656	0.96
33	34	0.0031	0.17	13.6	3.4	1	23	1697	1719	1697	1719	0.98
34	34	1.2	69	5.4	0.7	1	21	1725	1745	1725	1746	0.93

Sequence Information

Coding Sequence: ATGAGTTTTTTTTGCAGATCGGACGATGAAGAAGTGAACTACTGCTGCAATATCTGCACTAAGTTATTCCCTGACAAAGATGCGTTTTTCAAACACCATCTAGGGCAGTCTGGACGCACATTTATCTGTTGCAAATGCAAGAAAAAGTTCGCGAACGCTAACCACTTGTACGCACACTTGGACAAGCATAAAGGGCTTGAAATTCCAGAGGGCGATCAGGTTCTGGAAGAAGTAGTTTTGAACTACGATGACAACACTAAGCTCTTGTACATTTTGGACGACTCTACCGTGGCTTCAGGAGTTTCTCCGAAACGAAAGGTGGAACTGGACACGGTTCGCAAGGTTCAGCTGGATCACGGCTACGGTCTTCCGAGCTACGTCGAGCAAGCCAATAGAGAAACCGAAAGCGCAGTAGCTGCCATCACGCCCAACAGCAGAACGCCTCATTCCAGCAGGAGGACTCCGAAACGCCGCAGCATCGTTCCTGATTTTTCATCTCCGAAGTACATTTACGTCGAGGCGAGTCCCGAGATCGAGATCGCCCATTTCAAGTGCTTGCGATGCGAGCAGCTGTTTATCAACAAGTTCGGATTTTTGCGGCACACCGAGAAGGGCAAGTGTTATATAAACACTTGCGACGTTTGCGAAGCCACATTTGACAAGAACAGCGAGTTCTACGAACACTACTGCCAGGAGCACACGGAACGAGCGATTTGCAATTTTTGCTTTAGAACTTTCATGTACGAGAAAAACGTGAAGGAACACATGCTGAGACACTTGGACCAGTTCCGGCACCGGTGCGAGAAGTGCAACAAAGGCTTCTACACGACTCGCGAGTTCAGAAACCATTACAGGAACAGACACATGGGGATCAGACACACTTGCAGCGTCTGCGAAAAGAGCTTCGCAGACGAGACCAAGAGCAGGAGGAAGAAGCGCCAGGCAGTTGCCGGCGAGAAGCCTTGTCCTCACTGCAGGAAGGTTTTTTCAAACAACCGGAAGCTGAAGAAGCACCTGATTTCGCACAGCAATTTGCGACCGCATTCCTGTGACATTTGCGATAAGAAATTCAAACGGAAATACGACATCACGATTCACAAACGGAGCCACTTGCCTAGCGATAAGTACAGCTTCCAGTGCGATTTTTGCTTGAAAGTGCTCCGATCGAAAGGTTCCCTGACGACGCACCGGAAACGGCATTTGAAAGACTACAAGCAGATATGTTCCGTTTGCAATGCTGGTTTCGTGACCAATCAAGAATACAATAACCACATGGGTTCGAAACACGGCACAAGTTCACATATTTGCGACGTGTGTGGAAGGAGTTGCTACGACAAAGCAGCTCTTCAAGGTCACATGGCCAGACATGCCAAAGACTACGAGACAAATGCGAATTTCAAGTGCGATCTTTGCAACAAAACGTTCCTCCAAGAGAAGTATTTGAAGCACCATTTTACGAGAATACACAAAGATGGCGGGCAGCGGTACATTTGTGATTTTTGTGGTAAACGGTTGGGATCCAAGACGAGTCTGAGGGACCATTTGCTGATTCACCAAGGTTTGAAACCTATCGTTTGCAAGGAATGCGGAAAAGGATTCGCTCTGCGGACGACTCTGAAGGCGCACATGCGCATTCACACTGGTGACAGACCGTATGCTTGCGATCAGTGCGGGAAGGCCTTCACACAAAGAACTTCTTTAACCATCCACAGCAGATATCATAGCGGCGAGAGACCTTACATTTGTGAAATATGCCAAGTGGGATTTATTGAAGTAAATTGCTCAGTTTTCAGGAAATCTGATATAAATCGATTCTGCGATGTTTTACGGACGAAGAAAGTCGTGCCATATCCAGATTTTGACGGTAGTCCTGAAGACTCGGATGAGAGGTCCGGGTCAGAGGAATATGTACCGACCAAAAAAGGGGAAACGGAAACAGAAACTGACGAATCAGAAGGACTGGGCGAAGAACCGACGAACCGTGTGAGGAAGAAACTCGACCTGAAATATTCCTGCAGAGAGTGTTCATTAAAATTTGCCAAACCAGCGTCTCTGGAGAATCACACGCGACTGAAGCATCCGAAAACCGCCAGCGAGCTGTGCGATGTTTGCGGAAAGGCGTTCAGATTCAGACACAAGTTGAATGTTCACTACAGGATCCACACGGGGTACAAGCCGTTCTCGTGTGGGTATTGTGGCAGGTCTTTCGACAGGAAAGACAACTTGCGCACGCACGAGCGCTGTCACACTGGCGAAAAACCTTACATGTGCCAGTATTGCGGGAAAGGTTTCAATCAGAAGGGACCTCTTACGATACACATCAGAACACATACTGGCGAGTTTCCGTTCACGTgcgatttttgtaaaaaagcATTTTCTTCTGGAGGAGCCCGGAACGCTCACAAAAAGAAATGTACAGGTTTAGAGACAGTAAGTCCTATTGATCTGAATTCGGAACTTGAAGAATCTGACAACGCAAACGATGACAGCATCGACTCATCCGATGATACACCAATTGACACCAAAACGGGCCGTGAAGACAATACAAGTTtggatgaatttttaaaattcatagaACAACCACTTGATAGAAACGCCACAAAAGGAGGAAGAAGTGTAACGCTGACAGAAGAAGCTCAGGAAGATGAAGGCTTTGCAGATACAAGATACAATAAGCCACAAGCAATAAAATCGATTTATATGTGCGGCGGCTGCGTTACCAAGTTCCCTTCGCTGGACTCTTTACAGGAACACGCTGCTTTGCGTAACTGCTTTCCGGAGAAGCACTTTTGCAGAACTTGCGACGAGAGCTTCGACGATCGCAAGGATTTAATCAGACACAGGAACATTCACAAGACACCCAAATCCAAATTGCTCTGTTCGTACGGCTGCCAGAAGGCATTCAGCAGCATCAGTGCGAAagagttccatcaaaaattctaTCACACTGATGATTTTGACATGACACCCGCCGGTGTCTACCAGTGCAAGCATTGCGAGTTTCGGGTCAGCAACATCGTGAAAATCCGAAACCACGCTTTGAACCAGCACGTAAAGGTCAAGAACTGGTTGTGCGACATTTGCGGGAAGTGTTTCATGGGAAGCAAGGAATTCAAGGTTCATGTTGCCCGACACAACGACGAGAAAACTTTTTTGTGCAAGATTTGCGATAAAGCTTTCAGGACCAAGGTCGATCTAGGGCGTCACATGAATTCGCACTGTACAGTCAGGAGACACGCTTGCGAAGAGTGCGGGAAGACGTACAAAAACGTGTACAAGATGCGACTGCATCAGAGAAGGAACCATTATGGGCCGGAAACAAGCAACGACTTAGAAGAAGAACTGAGGAACTCTCCAAATGATTTCGATGATGATGAGGACGGTCCACAAGAAATCATTCGAATTATTTCAGATATCGAATCTTGTCAATCTTCTACGAATCCAGCTGATCTGGGAGTCGAACTCGATTGCGTTTCAGATGATTCAGACCAGTTCAACCCTTGCGAAGATAAATCTCTTGTCCATCCAAAGAAAGTCGAAATTATAATTACTGACATCCAGGAGATGACTCACAAAAGTCACGAAACAttgttggaaaaagtaactCCAAAAATTGAACCCTCTGTTTCAACTGGAAAAAAGAATCTGTCTCGAAAAAGGCCGAAGACACAGCGTCGCGTGGGACCGTATCTTCCCCTGGAACAAGTCAGAGCAATATCGTACATGTGCAGTTCGTGTAAGACCAAGTTCCTTTCATTGTCTGCTCTGACAGAGCACTCTGATACTTGCCCTGGCCGGAAGGGACCGAAGCCAAAGTCCATTAGTGGGCTACACAAAAAAAGACGGCTCACCTGTCCCATTTGCAAAATGTGTTTCTGCTCTGCATCCAGCAAATTGAGACACAAGGTCATGTTCAACAAGCTGCCACGTGAACAACACATAGAACAAGCGAGAGCCAGCGAACGACGAGATTGTCCGCATTGCGGCGAACAGTTTGTCTCAACAGATGCGTACGACACTCACCTAAGGCAGTACCACACGGCCAGCTATGACATGATAGGCACGAGAAAGTTGCGATGCAAATTGTGCGAGTTCACGAGCCAGACTCTGAGCAAGATGAGAATTCATTGTGTCACCACGCACGGCAGCGAGAAACCTTTTCGCTGCAAGTTTTGCCCTAGGACTTACTTGAGATCGTGCGACATGACCCGTCATATGGAATCGCACAGCGATAAGAGGAAggcaACCAGACATGAGATAAAAGGCGCATTGACTATAAAGTTCCAAAATAACTCGGATGATGACGATGACGACAACCCAGAGGAAATCATTCGAATTATCTCAGGAACCGAAACATGTCCATCTCCTGCGACTATAGCTGATCTGGGAGTTGAATTGGATTGCGTTTCAGATGATCCAGATGAATCCGACAGTTTTGCTGAAGCATATGGATCTCCTCTAAATGATATCGAAATTTTAGTTACTGACAATCAGATGACTCCGGAAAGCAATGAACCATTGTCTGACAAATCAGAAACACCAATAATTGATTCCACTAGTGGGAAAAGGAATCTGTCTCGAAATAACCAAAACACACAGCGTCGTGTGGGACCGTATCTTCCCCCAGAACCAGTGAAAACTTCGTACATGTGCGGTTTGTGCAAGGACAAGTTCTCTTCATTGCCCGCTTTGATCGGCCACTCCGAAATATGTCCCATCCGAAACGAAACGGGACAAAAGTCGAGCGGTGGCCTGCAGAAAAGGAACGAAGGACGATTCAGCTGCTCTGTTTGCCGAATGACCTTCCACTGCAAATTCAACAAAACCAAGCACCAGGTCATGTTCAAGAAGGTGTCTCGTGAACAACACATAGAACAAGCGAGAGCCTTTAAGCGACGAGGTTGTCCGCATTGCGACAGGGAGTTTGTTTCAGATGATGCGTACGATTCTCATCTGAAGCAGTACCACACGGCCAGTTACGACATGATAGGCACAAGAAAGATGCGATGCAAATCGTGCGCGTTCACGTGCGAGAATCTGAGAAAAATGAGAGTTCATTGTGTCAGCACGCACGACAGCGAAAAGCCTTTTCGTTGCAAGTTTTGCGAAAGAACTTTTTTGAGATCGAGTGACATGACACGTCACATGACCTCGCACAGTGATGTGAGAAAATATTTGTGCGATTTGTGCGGGGCAGAGTACAAAGCGAGATGCAAGTTGCTCCGGCACCAGAAGCTTGCTTGCAGATATAATAAATGTCGTATGTGA
Protein Sequence: MSFFCRSDDEEVNYCCNICTKLFPDKDAFFKHHLGQSGRTFICCKCKKKFANANHLYAHLDKHKGLEIPEGDQVLEEVVLNYDDNTKLLYILDDSTVASGVSPKRKVELDTVRKVQLDHGYGLPSYVEQANRETESAVAAITPNSRTPHSSRRTPKRRSIVPDFSSPKYIYVEASPEIEIAHFKCLRCEQLFINKFGFLRHTEKGKCYINTCDVCEATFDKNSEFYEHYCQEHTERAICNFCFRTFMYEKNVKEHMLRHLDQFRHRCEKCNKGFYTTREFRNHYRNRHMGIRHTCSVCEKSFADETKSRRKKRQAVAGEKPCPHCRKVFSNNRKLKKHLISHSNLRPHSCDICDKKFKRKYDITIHKRSHLPSDKYSFQCDFCLKVLRSKGSLTTHRKRHLKDYKQICSVCNAGFVTNQEYNNHMGSKHGTSSHICDVCGRSCYDKAALQGHMARHAKDYETNANFKCDLCNKTFLQEKYLKHHFTRIHKDGGQRYICDFCGKRLGSKTSLRDHLLIHQGLKPIVCKECGKGFALRTTLKAHMRIHTGDRPYACDQCGKAFTQRTSLTIHSRYHSGERPYICEICQVGFIEVNCSVFRKSDINRFCDVLRTKKVVPYPDFDGSPEDSDERSGSEEYVPTKKGETETETDESEGLGEEPTNRVRKKLDLKYSCRECSLKFAKPASLENHTRLKHPKTASELCDVCGKAFRFRHKLNVHYRIHTGYKPFSCGYCGRSFDRKDNLRTHERCHTGEKPYMCQYCGKGFNQKGPLTIHIRTHTGEFPFTCDFCKKAFSSGGARNAHKKKCTGLETVSPIDLNSELEESDNANDDSIDSSDDTPIDTKTGREDNTSLDEFLKFIEQPLDRNATKGGRSVTLTEEAQEDEGFADTRYNKPQAIKSIYMCGGCVTKFPSLDSLQEHAALRNCFPEKHFCRTCDESFDDRKDLIRHRNIHKTPKSKLLCSYGCQKAFSSISAKEFHQKFYHTDDFDMTPAGVYQCKHCEFRVSNIVKIRNHALNQHVKVKNWLCDICGKCFMGSKEFKVHVARHNDEKTFLCKICDKAFRTKVDLGRHMNSHCTVRRHACEECGKTYKNVYKMRLHQRRNHYGPETSNDLEEELRNSPNDFDDDEDGPQEIIRIISDIESCQSSTNPADLGVELDCVSDDSDQFNPCEDKSLVHPKKVEIIITDIQEMTHKSHETLLEKVTPKIEPSVSTGKKNLSRKRPKTQRRVGPYLPLEQVRAISYMCSSCKTKFLSLSALTEHSDTCPGRKGPKPKSISGLHKKRRLTCPICKMCFCSASSKLRHKVMFNKLPREQHIEQARASERRDCPHCGEQFVSTDAYDTHLRQYHTASYDMIGTRKLRCKLCEFTSQTLSKMRIHCVTTHGSEKPFRCKFCPRTYLRSCDMTRHMESHSDKRKATRHEIKGALTIKFQNNSDDDDDDNPEEIIRIISGTETCPSPATIADLGVELDCVSDDPDESDSFAEAYGSPLNDIEILVTDNQMTPESNEPLSDKSETPIIDSTSGKRNLSRNNQNTQRRVGPYLPPEPVKTSYMCGLCKDKFSSLPALIGHSEICPIRNETGQKSSGGLQKRNEGRFSCSVCRMTFHCKFNKTKHQVMFKKVSREQHIEQARAFKRRGCPHCDREFVSDDAYDSHLKQYHTASYDMIGTRKMRCKSCAFTCENLRKMRVHCVSTHDSEKPFRCKFCERTFLRSSDMTRHMTSHSDVRKYLCDLCGAEYKARCKLLRHQKLACRYNKCRM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -