Basic Information

Gene Symbol
-
Assembly
GCA_963576865.1
Location
OY756415.1:3320535-3326288[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.0085 0.88 11.2 0.4 1 23 88 110 88 110 0.94
2 15 0.008 0.83 11.3 2.4 1 23 161 184 161 184 0.93
3 15 0.021 2.2 10.0 0.2 1 23 211 234 211 234 0.97
4 15 0.0003 0.031 15.8 1.0 1 23 260 282 260 282 0.98
5 15 7.5 7.8e+02 2.0 0.1 1 8 286 293 286 298 0.86
6 15 0.65 67 5.3 0.7 1 23 357 380 357 380 0.90
7 15 0.66 69 5.3 2.1 1 23 407 429 407 430 0.94
8 15 4.8e-05 0.005 18.3 1.9 1 23 451 473 451 473 0.99
9 15 0.0014 0.15 13.7 0.1 1 23 477 499 477 499 0.98
10 15 0.00018 0.018 16.5 0.4 1 23 504 527 504 527 0.97
11 15 0.0056 0.58 11.8 3.3 1 23 533 556 533 556 0.95
12 15 0.0001 0.01 17.3 0.2 1 23 563 586 563 586 0.97
13 15 0.00088 0.092 14.3 2.9 1 20 592 611 592 614 0.96
14 15 1.3e-05 0.0013 20.1 1.2 1 23 620 642 620 642 0.99
15 15 0.00039 0.041 15.5 4.8 1 23 648 670 648 671 0.96

Sequence Information

Coding Sequence
ATGACCATGTCAGAATTATCGCTACACGTAGAACTTGAACATCAGCGTTTGACCGAAGAAGACATAAAAAAAGCCATCAATGATTCAAAAAGATTCCGCTATGAGTCCATAAAGGTCAACGTGTTAGACTTTAACTGCAAACTTTGCGACGATCAAATAGTCACATTTGAAGATCTCAAATGCCATTTAGTGAATAAACACAACAGACGAATAGACAGTGCCCATACCGGTATTTTGCCGTATAAAATTACGAAGAACGATTTCATCTGTGCATTGTGTGAAAAGACATTTGAAAATTACGTCCGCCTGTCTAAACATTTAGATGATCACTATCCGAAATTTGGGTGCGATCAATGTGGTGCAGGTGATGGCAAGAAGTTCTACGAAATCTACAAATCCAAATGGGAACTAAGGAGCGGAGCTCTAGCTCTTATAAACAGCTCCAACGCTCTTCCCTTCAGAACAACGAACCGTTACTATTTTTTGTGCTTTTACTGTGAGAAATCATACTCTGAATTTTCTGAACTGGAACACCACAATTCCACTGAACACCAAGTTACCGAGAAACAAATAATGGATTTTCTTCTAAAACTTGACATGAAACAAAAAGTCAAAGTGAATTTTCCAAATTTCGAATGCAAGCTCTGCAATTATGAAGCTGGAGATTATGGCAAACTGAGGGACCATCTCAGATCTATTCACGGGAAGAAATTAGACGTAAATAACAAAGAAGTTAAATGGGATAGAATCTTCCCTTATCAGATCGATGCAGAAGGATTCAAATGCGTCCTGTGCCCACAGAGTTTCTTTAGCTACAAACTATTGAACCAACACTTAAACGTCCACTATCTTAACTATGTATGCGAGATTTGCGGCGTCGGGTCCGCAACCGAACAGCGTGATGACAACACCACGACCAACACTAAAGTTAAAGTGATAAACGCCCGTAACAAAACAAAGAAAGCAAGCAGCTTCGAATACAACCAACAGAAAAAAGCTGGTAGAAACGGAACCGTGGCTTTGATCACCAGCTCCAACGCCTTTCCCTTCAAGTGGTGGAACAACCACTACTTATGCTTTTACTGTGAGGAAAGATACTTGGATTTTTCCAATCTTGAACAACACAACTCAAGCGAACATCAAGctactgaaaaacaaataatgaaatcTCTCGTTAGGCTTGGGAGATaccaaaaagtcaaagtcaattttacaaattttgtatgtaagctCTGCAATCATATTGCCGAGGACTATAACAAACTAAAAGATCATCTTGGCTCACATCATCAGATGAAATTGGACGTGAACAACGATGGGGTCTTTCCTTATCGCATCGATTCGGAGGGATATAAGTGTGCAATGTGCCCGCAGAGCTTCCATAATTACAGGTTATTAAACCGGCACATTAACATCCATTTTCCTAATTTTGTCTGCGACCAATGCGGAGTCGGGTTCGCAACAGACGAGCGATTAAAGGCTCATACGCAGAGTCATGTAAGCGGGTCATACAAATGCGATTTGTGTGATAAAATTTTTAGAAGAATATCTGCGAAGAAGGATCATATCGAGAGAATCCACATGAAAGTGAAAAAACACAGATGCCCCCATTGCAAAGAAATGTTTAAGGAGTACGGTCAGAGGATAAAACACATGGTCAGGATACACGGTGTCAAGGTGCCAGAGTTTCGATGTACGATGTGTCCCAAAGTTTATATGTTTAGTGGACAATTAAGAGTTCATGAGCGAGTAGCCCATTTCAAAACAAGAAAGTACGAGTGTGATATATGCAAGAAAACGTGTTCTAACGCATCTGTGCTTAGAGATCACATGGTATGTCATAGTGGCGAGAGGAATTACGAGTGTCAGGTGTGCAAAAAGAAGTACGGTCGGAAGAAAACATTGGTGGAGCACATGCGAATACATAATAACGACAGAAGATTTGTGTGTCAATATTGCAACAGTGCATTTGTGCAGAACTGCAGCTTAAAGAGTCATGTGAGGACTCACCATCGGAATGAAGTTAAAGTtgaataa
Protein Sequence
MTMSELSLHVELEHQRLTEEDIKKAINDSKRFRYESIKVNVLDFNCKLCDDQIVTFEDLKCHLVNKHNRRIDSAHTGILPYKITKNDFICALCEKTFENYVRLSKHLDDHYPKFGCDQCGAGDGKKFYEIYKSKWELRSGALALINSSNALPFRTTNRYYFLCFYCEKSYSEFSELEHHNSTEHQVTEKQIMDFLLKLDMKQKVKVNFPNFECKLCNYEAGDYGKLRDHLRSIHGKKLDVNNKEVKWDRIFPYQIDAEGFKCVLCPQSFFSYKLLNQHLNVHYLNYVCEICGVGSATEQRDDNTTTNTKVKVINARNKTKKASSFEYNQQKKAGRNGTVALITSSNAFPFKWWNNHYLCFYCEERYLDFSNLEQHNSSEHQATEKQIMKSLVRLGRYQKVKVNFTNFVCKLCNHIAEDYNKLKDHLGSHHQMKLDVNNDGVFPYRIDSEGYKCAMCPQSFHNYRLLNRHINIHFPNFVCDQCGVGFATDERLKAHTQSHVSGSYKCDLCDKIFRRISAKKDHIERIHMKVKKHRCPHCKEMFKEYGQRIKHMVRIHGVKVPEFRCTMCPKVYMFSGQLRVHERVAHFKTRKYECDICKKTCSNASVLRDHMVCHSGERNYECQVCKKKYGRKKTLVEHMRIHNNDRRFVCQYCNSAFVQNCSLKSHVRTHHRNEVKVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-