Basic Information

Insect: Anania hortulata
Gene Symbol: topi
Assembly: GCA_963576865.1
Location: OY756417.1:1015055-1035368[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0033 0.34 12.6 4.1 1 23 206 228 206 228 0.99

2 12 0.00046 0.047 15.2 1.4 1 23 235 258 235 258 0.98

3 12 6.2 6.4e+02 2.2 4.5 1 23 262 284 262 284 0.93

4 12 0.028 2.9 9.6 4.7 1 23 289 311 289 312 0.95

5 12 0.0008 0.083 14.5 1.0 1 23 316 339 316 339 0.96

6 12 0.00072 0.075 14.6 0.5 2 21 352 371 351 372 0.95

7 12 0.0046 0.48 12.1 0.1 3 23 385 405 384 405 0.96

8 12 0.00036 0.037 15.6 1.3 2 23 412 434 411 434 0.96

9 12 5.4e-05 0.0056 18.2 0.7 2 23 454 475 453 475 0.97

10 12 7.1e-06 0.00074 20.9 0.7 1 23 481 503 481 503 0.99

11 12 1.7e-05 0.0018 19.7 1.0 1 23 509 531 509 531 0.94

12 12 7.9e-07 8.2e-05 23.9 1.7 1 23 537 560 537 560 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0033	0.34	12.6	4.1	1	23	206	228	206	228	0.99
2	12	0.00046	0.047	15.2	1.4	1	23	235	258	235	258	0.98
3	12	6.2	6.4e+02	2.2	4.5	1	23	262	284	262	284	0.93
4	12	0.028	2.9	9.6	4.7	1	23	289	311	289	312	0.95
5	12	0.0008	0.083	14.5	1.0	1	23	316	339	316	339	0.96
6	12	0.00072	0.075	14.6	0.5	2	21	352	371	351	372	0.95
7	12	0.0046	0.48	12.1	0.1	3	23	385	405	384	405	0.96
8	12	0.00036	0.037	15.6	1.3	2	23	412	434	411	434	0.96
9	12	5.4e-05	0.0056	18.2	0.7	2	23	454	475	453	475	0.97
10	12	7.1e-06	0.00074	20.9	0.7	1	23	481	503	481	503	0.99
11	12	1.7e-05	0.0018	19.7	1.0	1	23	509	531	509	531	0.94
12	12	7.9e-07	8.2e-05	23.9	1.7	1	23	537	560	537	560	0.98

Sequence Information

Coding Sequence: ATGGGAGAAACACTTGCTTGTCGTCTGTGTTTATCAACAAATATCAAACTCATCAATATGTTCAAGTTTCGTCTTCAATCAGCGTACTCCATTCTTACTGGAATAGAGATGACCTCCTCAGACGGGCTCCCTCCATACGCGTGCAGCATGTGCAGCACCCTGCTCGTCAGGAGTGCAACCTTCAAACGCATGTGCAACAACTCACAGGATTTACTGAAGTTTGCATCAGTCCAGCGagtgcTATCCACAGACTATATTCAGAATTTGAATGTCACGTCACCATTTTTATTCTCAATGAAAACCAACGAACCAATCGATTTCCCCGTCATAGAGGATATTAAAGAAGAAATATGGGATAACGATATGATTACTGATGATGATTACAAAGTGAAAGAAATCGAATCGAGCGATGAAGAACCGTTGTCTAGTAAACTTAGGAAAGATGTATCAGATTCACCTCAAGATCAAGTTGGAGACTTATTAGAGGCATTACCGGAGACACAGGACGATGATGATTTCCCGAATGGGGAAGTAGATGAAATGGTATTGACGAAGGAACAGCAAATAGAGGAAGTCCAGTCAAGGCAGACATCTATGAACTATTTGAACTCAATCTACAAATGTGGACATTGTTACAAAGGTTTTATGACGGACACAACTTACAAGAATCATATGATCAGACATGACCCGAGCAGCGGCGTTTATGAGTGCGAGATATGCCACATCCGTCTCACGCATATGCGGGCGTTGCGCGCGCATATCATGACCTCGCATGAGCGCAAGTTCGTGTGCAAGTTATGCAACCACGTCTCCAAGTCTAGgcaTAGAGCAAAGGAACATTCAAAATGGCATTGCGGCTTCACATTTGTCTGCAAGTTCTGTGGAGCGTCATTCACCAAGTCGACTAGTCACCTCACCCATATCCGCCTGCACCACCCGTCTAAACACACTTGCTATGTTTGCGGCGAGTCATTTATTGGGAAGAACGGCCTTAATATGCACAAGAAGAAAGCTCATAGAGATATGAAGATTTCAGAGTCGGATTCGGACACTAGATGCACAAATTGCGATGTCCAATTTCACAGTCCAGGCGCGTTGAAACGACACATGAATAATATGGGTGACGTGCTTTGCGACATCAGTTTGAGGCCGTGTACCCAGTGCGGGGAGAGTTGGTCGACGGAAGATGAACTCAAGGAACATCTCAAAGAACACTCCAAGGACGAGCAAGTCAAATGCAATGAGTGTAACCGAACGTTCGCGCACGAGCGTTCGTACGCGGTGCACTACCAGCGGGTACACTTGCGGGTGCGCGCTTCGAAGAAGGACGGCCACGCTAAAGCGCGACACGCGCCCGTCGTCTGCGAGATATGTGGCCTGAAGTGTATCTCGAACGCGTCGCTCCGCTACCACCAGCGCACGCACACGGGCGAGCGGCCCTACCAGTGCTCCGAGTGCCCCAAGCGGTTCAGCATCGCGCAGAGGCTGCAGATCCACCAACGCACGCACACCGGCGAGCGGCCCTACAAATGTGGCCTCTGCCCTAAAGCCTTCAAACACAAGGCCGCCCTTAACAGACACGACCGGGTCCACTCGGGGGCGAAGCCTTACTCGTGCGCGCACTGCGGCAAGTCGTTCTCTCAGTCGAACTCCATGAAAGTGCACGTTCGCACTGTGCACCTGAAGCTTCCCTCCCCCTACCGGCCACGGAGGCCTGCCGTCGAGTGA
Protein Sequence: MGETLACRLCLSTNIKLINMFKFRLQSAYSILTGIEMTSSDGLPPYACSMCSTLLVRSATFKRMCNNSQDLLKFASVQRVLSTDYIQNLNVTSPFLFSMKTNEPIDFPVIEDIKEEIWDNDMITDDDYKVKEIESSDEEPLSSKLRKDVSDSPQDQVGDLLEALPETQDDDDFPNGEVDEMVLTKEQQIEEVQSRQTSMNYLNSIYKCGHCYKGFMTDTTYKNHMIRHDPSSGVYECEICHIRLTHMRALRAHIMTSHERKFVCKLCNHVSKSRHRAKEHSKWHCGFTFVCKFCGASFTKSTSHLTHIRLHHPSKHTCYVCGESFIGKNGLNMHKKKAHRDMKISESDSDTRCTNCDVQFHSPGALKRHMNNMGDVLCDISLRPCTQCGESWSTEDELKEHLKEHSKDEQVKCNECNRTFAHERSYAVHYQRVHLRVRASKKDGHAKARHAPVVCEICGLKCISNASLRYHQRTHTGERPYQCSECPKRFSIAQRLQIHQRTHTGERPYKCGLCPKAFKHKAALNRHDRVHSGAKPYSCAHCGKSFSQSNSMKVHVRTVHLKLPSPYRPRRPAVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -