Basic Information

Gene Symbol
-
Assembly
GCA_032362555.1
Location
CM063564.1:2086426-2096867[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.021 1.4 10.1 5.1 1 21 385 405 385 407 0.95
2 11 0.0049 0.33 12.1 1.0 2 23 415 437 414 437 0.95
3 11 0.00043 0.029 15.5 1.9 1 23 441 463 441 463 0.98
4 11 9.1 6.1e+02 1.8 1.2 1 23 468 491 468 491 0.92
5 11 0.0068 0.45 11.7 0.2 1 22 531 552 531 556 0.93
6 11 0.025 1.7 9.9 1.3 2 23 575 597 575 597 0.94
7 11 1.2 83 4.5 0.8 3 23 617 638 615 638 0.94
8 11 0.00089 0.059 14.4 0.3 2 23 652 673 652 673 0.96
9 11 0.0024 0.16 13.1 0.2 2 23 679 700 678 700 0.96
10 11 3e-05 0.002 19.1 1.1 1 23 706 728 706 728 0.92
11 11 1.6e-06 0.00011 23.1 2.2 1 23 734 757 734 757 0.98

Sequence Information

Coding Sequence
ATGGTATATTACTGCTGTGTAAATGGTTGCAATAATAATAGTAAGAAGAGGGATCCAAATCATGTTATATCATACCACACTTTCCCTTCAAACCTTGAAGTAAAGCAGAAATGGCTGCGAGCGATCGGACGGCCTACCTGGGAGCCCCCGAGCTACACTCGCATTTGCAGTGCTCACTTTGATCAGGAGTATGTCAACCATGACAGCCACCGAGCAAGGCTCAAGGATGAAGCTTACCCCATTTATAATTTACCAccCAATTCAAATTTTGAGGCAACAGATATGGAAGTCTGCCGGATATGCCTTGACACTGACTCCAAACTTTACAGCCTCCAGGAAGGTCTGCTTAAAGAATGTATGGAAACCATCACAGGCTTTAATGATAAATATAACATAGAAGGTCTGCCTCGGTATGTATGCTACGAATGTGCAGGACTACTGAAGAAGTGTTACAGGCTGGTGCAAAGGAGCTTGACAGCTCAGGCCACGCTGCTTGACATTTTTGCTACTAATGGACAGATTACAAAATCGCTAATCAGGAAACAAGAAAGAGATCATTTGAACCTAAAATCGTCATTAGTGTCTCACACAACCACTCCAACATATTTATTCGAATTCAAATATGATGAAGACCAACAATATTCGTGTCTAACTAATAGCGAATTTATCATACACTCATATGAGAACAAGactgaaattaataatactatCCATATACTTAATAATGAATTGGTTAATAGTGATTTAGTTAATAGTGAAAATAAAGACTTTGTTGCTGTCGAATCGGATATTAAGAATGTGATGAAATCCGAAGTGAAATGTGAATATTTAAGTGATGATGATGTGAGAAATGACGGTGCGGACAGTGACTCCACTAGTGATATATGTTTAGCGGAACTTAGCGAtagaaagtataaaaataatagaagtgACTGCGAAGTTGTTGTCAAAGAAAATTGTAAGAATAagGTTAAGAAGAAAATTGATAGAAGTGAAAAGTCTAAAAGGACATCTCTTGATGGTTTTACTCCAGACGAGATAAATATGCAGGAACATTTCAATATTGTTAAACTAACACTCGAAGAACAAATCGAGGACTGGAAGAAAACGGTGGAGAATCGCCCATGGAAAGCTGTGACCAAGGGTAGGGTTTACCAATGTGATATATGCCACAAGATATTCGCTCACATCACGACGTATCAGACTCATCTAATGTGCCACGATCCGaGCCGAGGCAATGTGGAATGTTTGGTTTGCAAGCTGCGGTTCAAAAGCGAGTCTCAAATGAAGACTCACGCCAAACGCTCGCACGGCAAGAAGTTTTATTGCAAGGCGTGTCCTAAAGTCTTCAATAACAGCAACATGGCGAAGAAGCACCAGAAGCGGCACTCGGGCCACGTGTACGCGTGCGGCGCGTGCGCCTTCCGCTCGCGGCACGAGTCGTGCCTCAGCGCGCACGCGCGGGCGCAGCATGCGCGCGCCGCCTGCGCCGCGTGCGGCCGGCCCGCGCGCGGCCGCCGCGGCCTGCGGCAGCACTGGGCCGCCGCGCATCCCGGACTGCCGGAGCCAGAAAATATAACTAACACAGAATACCGTTGTGAGGAATGCAACTTGAACTTCAGTACAGAGGGCGCTCGGCGCGTACATCTTCTTACTTCTGCGCAACACAGGAAGAAGACTGACAATGGCACCACACTCCCACCAGACCCGTCTCTCAAGAACACGTGTAAATCTTGCGGTCTACAGTTCACGTCGCAAAAGGAAATGTTGAGCCACAGTCGCGAGCAACATCCGCGCCACAAATACAAGAAGATATGGCGACAACCGGGCGACAGTTACCCGACCAACTGCGAATTTTGCGGCGTGACAGTGAAAACAAGATGGGACCACTGGTGGCATGTTCGTCGTCAGCATCCCAAAGAGAAAGACTCGTATAGGCGGGTGTACACCGCCGTCTGCGAGACCTGCGGCAAGGGATTTCAGAGCCCGACGAAGCTGCGACTGCACGAACTCCGTCACGCGAGCCCCAGCGTGTCGTGCGAGACGTGCGGCCGGCTGTTCTACGACAAGTACACCATGGCGCGCCACGCCGCCACGCACACGCAGCTGCGGCCGCACGCCTGCCCGCACTGCCCGCGGGCGTTCAAGGTCAAGGGCAACCTGCAGAGGCATTCTGTTGTTCACACAGGCGCCACCCCATTTGAATGCACAATGTGTGACAAGAAATTCAAGCACGCGACCAGTTTGACCGTTCATGTGCGCACCGTACATTACAAACTGCCGCCTCCGCCGCGCAAGAAGCGGGGCCCGAGGAGACCTAAGAATAGAAGCGATATCAACAGCGATATgtga
Protein Sequence
MVYYCCVNGCNNNSKKRDPNHVISYHTFPSNLEVKQKWLRAIGRPTWEPPSYTRICSAHFDQEYVNHDSHRARLKDEAYPIYNLPPNSNFEATDMEVCRICLDTDSKLYSLQEGLLKECMETITGFNDKYNIEGLPRYVCYECAGLLKKCYRLVQRSLTAQATLLDIFATNGQITKSLIRKQERDHLNLKSSLVSHTTTPTYLFEFKYDEDQQYSCLTNSEFIIHSYENKTEINNTIHILNNELVNSDLVNSENKDFVAVESDIKNVMKSEVKCEYLSDDDVRNDGADSDSTSDICLAELSDRKYKNNRSDCEVVVKENCKNKVKKKIDRSEKSKRTSLDGFTPDEINMQEHFNIVKLTLEEQIEDWKKTVENRPWKAVTKGRVYQCDICHKIFAHITTYQTHLMCHDPSRGNVECLVCKLRFKSESQMKTHAKRSHGKKFYCKACPKVFNNSNMAKKHQKRHSGHVYACGACAFRSRHESCLSAHARAQHARAACAACGRPARGRRGLRQHWAAAHPGLPEPENITNTEYRCEECNLNFSTEGARRVHLLTSAQHRKKTDNGTTLPPDPSLKNTCKSCGLQFTSQKEMLSHSREQHPRHKYKKIWRQPGDSYPTNCEFCGVTVKTRWDHWWHVRRQHPKEKDSYRRVYTAVCETCGKGFQSPTKLRLHELRHASPSVSCETCGRLFYDKYTMARHAATHTQLRPHACPHCPRAFKVKGNLQRHSVVHTGATPFECTMCDKKFKHATSLTVHVRTVHYKLPPPPRKKRGPRRPKNRSDINSDM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00072880;
90% Identity
iTF_00072880;
80% Identity
iTF_00072880;