Basic Information

Gene Symbol
-
Assembly
GCA_963170755.1
Location
OY720683.1:23769185-23776243[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.24 78 7.2 3.6 1 23 235 257 235 257 0.94
2 16 0.061 20 9.0 2.9 1 23 263 285 263 285 0.98
3 16 1.5e-06 0.0005 23.5 3.7 1 23 291 313 291 313 0.99
4 16 4.5e-05 0.015 18.9 3.8 1 23 319 341 319 341 0.99
5 16 0.00011 0.035 17.7 5.0 3 23 349 369 347 369 0.98
6 16 5.7e-06 0.0019 21.7 3.1 1 23 375 397 375 397 0.98
7 16 4.3e-06 0.0014 22.1 3.6 1 23 403 425 403 425 0.99
8 16 5.1e-05 0.017 18.7 2.8 1 23 431 453 431 453 0.99
9 16 0.00026 0.087 16.5 1.5 1 23 459 481 459 481 0.98
10 16 0.00023 0.075 16.6 5.0 1 23 487 509 487 509 0.98
11 16 1.6e-05 0.0052 20.3 0.4 1 23 515 537 515 537 0.98
12 16 4.7e-05 0.015 18.8 7.1 1 21 543 563 543 565 0.95
13 16 2.2e-07 7.4e-05 26.1 0.9 1 23 571 593 571 593 0.99
14 16 1.1e-05 0.0037 20.8 2.4 1 23 599 621 599 621 0.98
15 16 1.9e-05 0.0061 20.1 1.8 1 23 627 649 627 649 0.98
16 16 2.4e-06 0.00077 22.9 3.6 1 23 655 677 655 677 0.98

Sequence Information

Coding Sequence
atggaaaataatacaaaaaatgaaaatCATCAGCATAATTTCATCAACACTGAAATATGTGGAAATATATCATCATCGGTACAAAAACAATGTTACAACCCCATAATTAAACAAGAACATAATTTACAAGATATGTTTAATCATTGTGATtcatacaattttttaaattctagaaATAATGAATATATTAATTACAACAGTGATATTCGTCATAATAAACACCATGAAAGTTATGTTTATTATAATCATTTAGAGAATAATCAGCATTATAATTATTACAGACCAAGTTTTTCAGATTATTTACAAAAATCAACAGATAGACCTGTAAATCTAATGTTTCAAAATCAAGTGAACATACCCTCAAATTTTAACAATTATAAAAGTAAATCAAATGACATATTTGAATATAAGAATGTATCACAATATCCCAGTTTTAATAATAAGGTTGCTGAAGATGGAATGGAAATTAAGAGAGAGCAATCAATAGAAGACATTCATAATAATCCAAGTGTAAATGAAGGAGAGGTTGTAACAGAAAATGGAAGTATCAGTGAAATAATTGAGAACACCAATATGGATCCTGCAGCAATTAATATAAATGATCATATAACATCTATACATGCTGATAAATATAATGTTTCACAACATTTTTTGTGCACTGATAAGGAAGTCTCAGAAACGACTGACAGTTTGACTAAAAAGCATGCATGTGATATTTGTTTTAAACGATTTAAGTGTAAAACCTATTTAGCAGCTCACAAAGCGATACACACAGGAAACATACCATTTAGATGTAGCATATGTAATAAAGAATGTCTTACAAAGCAACAGTTAATTTATCATGAGAAGATTCACAGTGGGAACAAGCCCTTCAAATGCGAAACATGCCCGAAAAGTTTTATGAGCAATAAAGACTTAAGGCACCATATCCGCACTCATACTGGAGAGAGGCCGTATGAATGTCAGATATGTCAAAGATGTTTTTCGTTAAAGAAAAATTATGAAACCCATTTAAGGGTACATACAAATGAGAAGCCATATGGATGTAAGACCTGTGGAAAATTATTTAGTCGAATGGATCATTTAAAGCATCATGTACGAACACATACTGGTGAAAAGCCCTTTAAGTGTGATATGTGTACGAAAACTTTCTCTCGAAAATTCCTATTGATGTTACATATAAGataTCACATGGGTATTAAGCCATATAAATGTGAAACATGCGGTAATTGCTTTGCCGAGAAGAATACTCTAACAAGACATATGAGAACACATTCAGGTGAAAAGCCGTATCGTTGTGAGCAGTGTGGAAAATGTTTTGCAGGCCGAAAGGACCTATTAACCCACAGTAAGACGCATACGGACGAAAAAGATCATAAATGTGAAGTGTGCCTCAAGGATTTCAAAACGCGGGCGTATTTGCTGGTCCATTTAAAAATACACGTGGAACAGAAACCGTACAATTGCCACCTGTGTGAGAAAGGTTACAATACCCGCGAAAAATTGACACACCATATCAGATCACATACAGGTGAGCGACCGTTCCAATGCACGATCTGTCAGAAGGCTTTCTTAAGTAAAGGCGAACTGACACGACACATCATGATACACACGGGTGAGCGACCGCATCAATGCAAAGACTGTTCAAAATCCTTCATCACCAAGAGCAAACTGAATCGCCACATGAAATGCCACTTGAACGAGAAAGAATACAAATGCACGTACTGCGAGAAGGCCTTCGCGCAAAAAGACGGTCTCACCACTCACATCAAGACCCACACAGGTGAAAAGGCGTTCGAGTGCAGCTACTGCAAGAAGCGCTTCATCACGGCGGAACACCTGAGGGGTCACGTCCGCTCGCACACGGGCGACAAACCGTTCAAGTGCAAGATCTGCGACAAGAAGTTCTCCCTGCGCGGCAACGTCAGCACGCACATGAAATTACACTCGGGCATCAAGCCGCATAAGTGCGAGAGCTGCGAGAAGAGTTTCGCGCAGAAGAGCACGCTCATGAATCACATGAAGACCCACAGGCACATGCAGAACACGATGATTACGGAGATCTTGAAACAGCAAATACCAACCGATCAGATCAAGCAGGAGGAGTACAACGAGGAAATAAAACAGGAGGTCGTTGATGATGAAGACGGGGATAACGGTGGCGGTATCCAATCTTATAATATTCCCGAGCACATCTCGATAGTTAGCAATATAAAAAGTGAACCCGAACTGATTGCAGCGCATGACATGAAACAGGAGATTATATAA
Protein Sequence
MENNTKNENHQHNFINTEICGNISSSVQKQCYNPIIKQEHNLQDMFNHCDSYNFLNSRNNEYINYNSDIRHNKHHESYVYYNHLENNQHYNYYRPSFSDYLQKSTDRPVNLMFQNQVNIPSNFNNYKSKSNDIFEYKNVSQYPSFNNKVAEDGMEIKREQSIEDIHNNPSVNEGEVVTENGSISEIIENTNMDPAAININDHITSIHADKYNVSQHFLCTDKEVSETTDSLTKKHACDICFKRFKCKTYLAAHKAIHTGNIPFRCSICNKECLTKQQLIYHEKIHSGNKPFKCETCPKSFMSNKDLRHHIRTHTGERPYECQICQRCFSLKKNYETHLRVHTNEKPYGCKTCGKLFSRMDHLKHHVRTHTGEKPFKCDMCTKTFSRKFLLMLHIRYHMGIKPYKCETCGNCFAEKNTLTRHMRTHSGEKPYRCEQCGKCFAGRKDLLTHSKTHTDEKDHKCEVCLKDFKTRAYLLVHLKIHVEQKPYNCHLCEKGYNTREKLTHHIRSHTGERPFQCTICQKAFLSKGELTRHIMIHTGERPHQCKDCSKSFITKSKLNRHMKCHLNEKEYKCTYCEKAFAQKDGLTTHIKTHTGEKAFECSYCKKRFITAEHLRGHVRSHTGDKPFKCKICDKKFSLRGNVSTHMKLHSGIKPHKCESCEKSFAQKSTLMNHMKTHRHMQNTMITEILKQQIPTDQIKQEEYNEEIKQEVVDDEDGDNGGGIQSYNIPEHISIVSNIKSEPELIAAHDMKQEII

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-