Basic Information

Insect: Amphibolips quercusostensackenii
Gene Symbol: lola
Assembly: GCA_032357855.1
Location: JAUELO010000085.1:6958046-6968321[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 27 0.074 36 7.4 1.5 2 21 77 97 76 98 0.94

2 27 0.00012 0.058 16.2 1.2 1 23 106 129 106 129 0.96

3 27 0.046 23 8.0 2.7 1 20 201 221 201 226 0.93

4 27 0.00087 0.43 13.5 0.2 2 22 282 303 281 303 0.94

5 27 0.47 2.3e+02 4.9 3.3 2 23 312 333 311 334 0.94

6 27 0.0022 1.1 12.2 0.9 2 20 385 403 384 405 0.94

7 27 1.3 6.6e+02 3.4 0.9 1 15 413 427 413 436 0.82

8 27 0.015 7.3 9.6 0.3 2 21 499 519 498 520 0.93

9 27 0.011 5.6 9.9 5.6 1 23 537 559 537 560 0.96

10 27 0.11 55 6.8 1.2 3 21 634 653 632 654 0.94

11 27 0.0081 4 10.4 0.1 1 21 754 775 754 776 0.93

12 27 0.0092 4.5 10.2 5.3 1 23 784 807 784 807 0.96

13 27 0.031 15 8.6 0.2 3 21 907 926 905 927 0.92

14 27 0.16 80 6.3 4.6 1 23 935 958 935 958 0.95

15 27 0.0069 3.4 10.6 0.3 1 21 1114 1135 1114 1136 0.95

16 27 0.36 1.8e+02 5.2 1.0 1 23 1144 1167 1144 1167 0.93

17 27 0.00015 0.073 15.9 0.6 1 21 1270 1291 1270 1292 0.96

18 27 0.0022 1.1 12.2 2.9 1 23 1299 1322 1299 1322 0.97

19 27 0.0012 0.57 13.1 2.6 1 21 1379 1399 1379 1400 0.96

20 27 8.7 4.3e+03 0.9 3.6 1 21 1408 1428 1408 1431 0.91

21 27 5e-05 0.025 17.3 0.3 1 21 1521 1541 1521 1542 0.95

22 27 0.19 96 6.1 3.4 1 23 1550 1573 1550 1573 0.97

23 27 0.00062 0.31 13.9 0.5 1 21 1616 1636 1616 1637 0.93

24 27 0.0051 2.5 11.0 3.3 1 23 1645 1668 1645 1668 0.97

25 27 0.24 1.2e+02 5.7 0.7 1 21 1698 1718 1698 1719 0.94

26 27 0.24 1.2e+02 5.7 0.7 1 21 1757 1777 1757 1778 0.94

27 27 0.0026 1.3 11.9 2.3 1 23 1786 1809 1786 1809 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	27	0.074	36	7.4	1.5	2	21	77	97	76	98	0.94
2	27	0.00012	0.058	16.2	1.2	1	23	106	129	106	129	0.96
3	27	0.046	23	8.0	2.7	1	20	201	221	201	226	0.93
4	27	0.00087	0.43	13.5	0.2	2	22	282	303	281	303	0.94
5	27	0.47	2.3e+02	4.9	3.3	2	23	312	333	311	334	0.94
6	27	0.0022	1.1	12.2	0.9	2	20	385	403	384	405	0.94
7	27	1.3	6.6e+02	3.4	0.9	1	15	413	427	413	436	0.82
8	27	0.015	7.3	9.6	0.3	2	21	499	519	498	520	0.93
9	27	0.011	5.6	9.9	5.6	1	23	537	559	537	560	0.96
10	27	0.11	55	6.8	1.2	3	21	634	653	632	654	0.94
11	27	0.0081	4	10.4	0.1	1	21	754	775	754	776	0.93
12	27	0.0092	4.5	10.2	5.3	1	23	784	807	784	807	0.96
13	27	0.031	15	8.6	0.2	3	21	907	926	905	927	0.92
14	27	0.16	80	6.3	4.6	1	23	935	958	935	958	0.95
15	27	0.0069	3.4	10.6	0.3	1	21	1114	1135	1114	1136	0.95
16	27	0.36	1.8e+02	5.2	1.0	1	23	1144	1167	1144	1167	0.93
17	27	0.00015	0.073	15.9	0.6	1	21	1270	1291	1270	1292	0.96
18	27	0.0022	1.1	12.2	2.9	1	23	1299	1322	1299	1322	0.97
19	27	0.0012	0.57	13.1	2.6	1	21	1379	1399	1379	1400	0.96
20	27	8.7	4.3e+03	0.9	3.6	1	21	1408	1428	1408	1431	0.91
21	27	5e-05	0.025	17.3	0.3	1	21	1521	1541	1521	1542	0.95
22	27	0.19	96	6.1	3.4	1	23	1550	1573	1550	1573	0.97
23	27	0.00062	0.31	13.9	0.5	1	21	1616	1636	1616	1637	0.93
24	27	0.0051	2.5	11.0	3.3	1	23	1645	1668	1645	1668	0.97
25	27	0.24	1.2e+02	5.7	0.7	1	21	1698	1718	1698	1719	0.94
26	27	0.24	1.2e+02	5.7	0.7	1	21	1757	1777	1757	1778	0.94
27	27	0.0026	1.3	11.9	2.3	1	23	1786	1809	1786	1809	0.98

Sequence Information

Coding Sequence: ATGTTTGTTGGCGAAGGGGACCAAGCCGAGGTTGTATGGGAATGCATAAATATATCTGATGAAAATGTAGAAAGCATCGCTAACCGGACAGATGAAATTTTGCGCGAAGGGAAACTggcaaagagaaataaaaaaagaagtcaTCCAGTCAGAGAACCCCAGGTCAAATACCTAACAAGATCTCGCTTGCGACTACCAGAAGagtccacaaaaaataaaaaagttcttgaATGCCCCAACAAGTGCGGAAGTTCCTTTTTCTACCAACACACTCTAGATAAACATGTTCGTCACATTTGTGATCAACCCATGAGATACAAGTGCCCATATTGTTCTCTTGTCTCTAGAAACCGTAACAACCTTAACGTCCATATAAAATTCCGACATCCTGGGTACAAGAATTACGTGATTGACACCTTTATCGGAAAAAATGAACCACTTTTCGAAGATGAATATGATACGTCTTATGAGCAGCACATTGAACACTCTTGGAATGAGGAACACGAAATCAAGATACTGAGCGTCTCGAGCCTTGCAAAATCTGAAGACATCAAACACGAATTTGAAGATACCAAGGACGAATCTATTATAAGCAAGAGATTCTCTTGCCCCAACAACTGTGGTAGTTCATACAAGCACGAATACACTCTAAAAGCTCATGTGGAGTTTGCCTGTCACCAAAATCAGGCACTGAACAACTTGCATCTGGAAGAAGAGGAATCAGAGCCCGGAACAAATGACTCGACAATGATGGATGTTACGAAGTTTGAGACTCCTGAGGAATTGCTGAATCCCATGGCACTTGCAGAaccttcagaattaaaaaatgaagatggTAAATTAGTTTGTCCTAAAAGTTGTGGAAGTACCTTCAGCACTCGAGGCAATTTGAATTACCATTTGCGTACATTGTGTGGAGTTGAACCAAGATTGGAGTGTCCATATTGCTCGCACCGAATGAAGCAGCCTTCTAATGGCTTCACTCACATCAAGACTCATCACCCTGATGCTCAGCTCTGTTTGTTGGATACCGTAACAGGTGAATTTGTTAGACGAAAGAAAGACATGGCAAACGCTGATACGACAAACATCGACGACTGTACACCTAAAGTTCCCGAGCCTAGAAAAATCTCTCCATCGAAGCTGGCTAAAACTTGTCAGAGCTGTGGAAAGGTATTCAAATTACGTCATACCTTGTCAAGACATCTCGCTGAAGGTTGTGGACAACCACCTCGTTTTAAATGTCCCTGGTGCGATTACCAAGTAAGGAGACTTTCGTACGCTTTCTTCCACGTGACAAAGAATCATCCAGGTTTAAAGGTCTACATGGTGGATTTGCTCACTGGAGAAAGCATCACCGATTCCACTCATATCAAGAAAGAAGCCGTCGAAGAGGTTAAGGAAGAGAAACCACTTGCTCCTAATCCAGTGCACTCTTTAAGACCTAAGAGAGCCCAGACCTCTGTTCCTGCTGGTCTTCAGAAAAAGAAACTGATGTGTCCAAAAGGCTGCGGTCAGTACTTCTTCTTTAAACCAAGTCTTCAGAAGCATATTAAATACAAATGCAGAAAAACTACTAAACCTTTCCAAAGCTCAGAATCTGCTCGATTCAAATGTTCCTACTGCGTTAATAGTTTTGTTCATCGTACGAGCGCCCTTAGACATCTAAGGACCCATCATCGCGGTAAGACAAAGATTGTGATTGATACCCATGTGGAGGAAATTGTACCGGAGACTGCTGCAGCGAAAGTACTTGAGTGTGATCAAGAGAGAAAGACTCAAACGCGGACTTTGAAGAATCAGAAGGAGAAAACCGATAAACTGCCAAAGTCCACTGATGATCAAAATGATACTGAAAAGACTGACTCGAATTCTCAGAACACTTCCGAGCTGATTCACTGCCCTAACAAATGCGGAAGTATGTTTGAGCATAGTTTCAATATTAGTCGTCATTTGCGTCAATCCTGTTCTAAAGTTCGTCGCTTCAAGTGTCCACATTCACAATGTTCTTACCGATCACAGCAGTTCAATTTAGTTGGAAAGCACATCAAGAGGAGTCATCGACTGAGCAAGATTTATGCTTATGATGTTTTCACTAAACAACTTGTCTACTCAGAACCTAAACGTCGTCAACGGTCTTTGGCGCTACCTAAAAAGGCTATACAGGAACCTGTTGTCTTATCGGAACCAGAAGTTGAACAGAAATTGGATTCAGTAGTTCCTAAAACATCTGCTAAAAAAACTAAAGTACAGAACCGCTATCCGTGTCCTAACAATTGCGGAAAATCTTTCAAAGTGGAACGCTCTGTAGACACTCACTTGAGGCTGATTTGTGGCCGTAGTCCTCGATACAAGTGTCCGTATTGCAGCCAAGTGTGCAGACATCAAGGGAATATAACTATCCATGTGAACCACCGACATCCTGGGAGAAGAATCTATTCGATCgatatattgaaaaagaaaacacCGAAGGAAGCAGGCAAGAAGacaaggaaagagaaaaagactGAAGAAATTCAGGAAGAAGCAGAAAAGGAACAACTTCCGATTGCAAGTGGATCAGATAACATGGATGATCAAAATGTCCCTGATAAAGAAACCTCTGAGGCTGTCTTCCAGCCACATTTTATGGATGTACCTGCCACACAGAAGGCCAAGAAGGCTAAGATCGCCAAGATGGCCAAAAAGTCCTTGCCTGTAATGAAGCAAAGATTGGATTGTCCCAACAAATGCGGTCGTCGTTTTATATCAACTCAAAGATTAAAAGTACACGTAAAATCAAACTGTAAAAACGCTCCCACTTTTAAGTGTCCACACTGTGAGATAGTTTGTGCACATTCGTGGAACATCGCTATGCATGTTAAACACCGTCATCCTCAATTTTATAGTGCTAATAAGCAGCAAGATTTCGGGACTGAAGTGAATCAGGAAAATAATGAGGATTTGAGAAAACAAAACGGAACGAGCGAACAATTGATTGATCTGAATGAAGAGATTACAGGTGGATCACAGGAAGTAGATCAGGTAGAACAAAGCATCAATATTGACGTTGCTAACGATATTGAAGAGGATGTAGAGATGGAAGAAAATGTACCCGAGGATGTGGAGATGGAAGAAAATGTAACCGAGGATGTCGATAATGACAATGCTATCCAGATGGAAGCTACTAATGACATGGATAATCCTGAGGTTCCGAATGACGAAGATGAAGATATTGAATTTGTGCTTGAAGATGAAAACGAGCTTGAACAAGAGACATCACATATAGTAGAGTCAAATACCACAGCCAATGTTTCCTTAAATACGAGTAACTCGATCAATACAATTTCACCGAAAAAATTCCCCTGTCCTAATAATTGTGGCAGTTTTTATTCTAATTCCAATAGTTTGAAGACTCATGTACGTTACGCATGCGGTCAAAATCCACGATTCAAATGTCCCTATTGCACGTCAGTCACTCGCCAAACTTCTAATGGTTATGCACATGTAAAGAAAATGCACGAGGGTCGTCAAATTTATCTGATTGATATTGTCACCAATAAGTTTATTTGTGGATCGAGGTATCAACCATCTATAAAAACAGCAGAGgttcttgaaaatcaaaatgttgGTCAGAATGATCTTGTTGAAAACCAAAATGCTCCTGCTAATCAAGACTTTGTTGGTATTGATCAAGTTGAAGCTATGGCTGATGATTCAAACGATGAACCTGATGAGCCAGATGAACCTATCGTAGAAGCTGAGGAAGAATTTGGGACACCTGAAGCGGAAGCATCGCCAAAATCATCACCAGAGAAGAATAAACCTTTCAACTGTCCTAACAACTGTGGCAGTTCATTTAGCCATGAGTACAGCTTAACCAGACATATTAGAGATCAATGTGGACCTCCTCGTTATAAATGCCCCCATTGCTTCTACATCACTAGACAGCCCTCGAATGTGTACACCCACATCAAAAATAAGCATCCCGATGAGAGGATCTACATGATTGATACTGACATGAACCAAAGCTGCGACGAACCAGGggTGGTAAAAGCATGTTTTTCAGGTGAAAAGTTCAAGACTGCCTATCTTGGCAATTGCTGTGatatcaCGGCACATGCGTTTGAGATTCCTCGATCCGTGCCATTTATACACACGTGTTCTACTTGTAAGAGCACTTTCCAAAGGAAGAGTAGTCTCGTAAGGCATATACGCTACACTTGCGGCAGCGAACAACGCTTTAAGTGTCCATATTGTTACAGTAGAAGTAATTTAGCTAGTAATGTGTATAAACATGTTCGCTGCTTTCATCCAGAACGTGAAGTTTTTACTATTGATGACAAAACGACTCATCATATTCACCAGTCGATTATGAGGCCTCGCGAAAACATTCTCAAGGGATTGTGTTTGTCTGCCCAACTCACAATTGTTCAAAAAAGTTCAGCTGGAAGGGAAATCTTAGCAGACATTTGCGATACGAGTGCAATGTGCAACCTCGATTTCAATGTCCGCATTGTCAGTATAGATAGTTCACAAGAGGACGTTTTAGCGGAATTTGATGTATCTTCAAGGAAAATGTTTCCCTGTCCAAAATGTCCAAGCACTTTTCGACAAAAACCGAGTCTAACGAGACACATCAAGTACGAATGTTCTCAGCCACCGAGATTTTCATGTCCCTATTGTCAGCACCGAAGCAAAAAAACTTCAGATATTTATGTCCATGTTCGTAGAAGACATATTGATTGCCAAGTTTTTGCGATCGATATTCACGGCGATCCCAGCGATGcagtttttcAACTTTGTTCTCTGCCCTGGGTCGAAGAAAAATCCACAGGAAGAAGTTCAAGAAAATCGAGGGCGCGATTTCCATGTCCGCGCTGTCAAAAAAGTTATACGACTAAAAGTGCAGTTACGGCTCATTTTAAATACGATTGCGGCCGACCACCGAGATTTCAATGTCCCTATTGTGGAAGGCTtagcaagaaaaaattcaatatacagGATCACATTCGTCACAAACATCCCTCTAAATCAGTCGTCTgtGGCATGTATGGGTACCACTATCAAGAAGAAAACTTCGAGGTTCAGTTTAACCCGGCTACTGGCAAGTTTCACTGTCCGAAATGTAATAATGGCTATGGGAGGCGGGACAACATGGTGGGACATTACAGATACCAGTGCGGAAAAAGTCCCAGGTTTCAGTgtGTCAAACATGGTGGGCTGCATTTTCAAGAAGAGAACTTCTGGCAGAAGCTCGAGGTTCAGTTTAACCCGGTTACCGGCAAGTTTCACTGTCCTAAATGTAATAATGGCTATGGGAGGCGGGACAACATGGTGGGACATTATAGATACGAGTGCGGGAAAAATCCCAGGTTTCAATGCCCCTATTGTTCTATGTGCGCCAAAAAAAGTTCCAACATCTACCAACACGTCAGAACTGTCCATCCTAACGAGCAAGTCACACTTGTTAGActctattga
Protein Sequence: MFVGEGDQAEVVWECINISDENVESIANRTDEILREGKLAKRNKKRSHPVREPQVKYLTRSRLRLPEESTKNKKVLECPNKCGSSFFYQHTLDKHVRHICDQPMRYKCPYCSLVSRNRNNLNVHIKFRHPGYKNYVIDTFIGKNEPLFEDEYDTSYEQHIEHSWNEEHEIKILSVSSLAKSEDIKHEFEDTKDESIISKRFSCPNNCGSSYKHEYTLKAHVEFACHQNQALNNLHLEEEESEPGTNDSTMMDVTKFETPEELLNPMALAEPSELKNEDGKLVCPKSCGSTFSTRGNLNYHLRTLCGVEPRLECPYCSHRMKQPSNGFTHIKTHHPDAQLCLLDTVTGEFVRRKKDMANADTTNIDDCTPKVPEPRKISPSKLAKTCQSCGKVFKLRHTLSRHLAEGCGQPPRFKCPWCDYQVRRLSYAFFHVTKNHPGLKVYMVDLLTGESITDSTHIKKEAVEEVKEEKPLAPNPVHSLRPKRAQTSVPAGLQKKKLMCPKGCGQYFFFKPSLQKHIKYKCRKTTKPFQSSESARFKCSYCVNSFVHRTSALRHLRTHHRGKTKIVIDTHVEEIVPETAAAKVLECDQERKTQTRTLKNQKEKTDKLPKSTDDQNDTEKTDSNSQNTSELIHCPNKCGSMFEHSFNISRHLRQSCSKVRRFKCPHSQCSYRSQQFNLVGKHIKRSHRLSKIYAYDVFTKQLVYSEPKRRQRSLALPKKAIQEPVVLSEPEVEQKLDSVVPKTSAKKTKVQNRYPCPNNCGKSFKVERSVDTHLRLICGRSPRYKCPYCSQVCRHQGNITIHVNHRHPGRRIYSIDILKKKTPKEAGKKTRKEKKTEEIQEEAEKEQLPIASGSDNMDDQNVPDKETSEAVFQPHFMDVPATQKAKKAKIAKMAKKSLPVMKQRLDCPNKCGRRFISTQRLKVHVKSNCKNAPTFKCPHCEIVCAHSWNIAMHVKHRHPQFYSANKQQDFGTEVNQENNEDLRKQNGTSEQLIDLNEEITGGSQEVDQVEQSINIDVANDIEEDVEMEENVPEDVEMEENVTEDVDNDNAIQMEATNDMDNPEVPNDEDEDIEFVLEDENELEQETSHIVESNTTANVSLNTSNSINTISPKKFPCPNNCGSFYSNSNSLKTHVRYACGQNPRFKCPYCTSVTRQTSNGYAHVKKMHEGRQIYLIDIVTNKFICGSRYQPSIKTAEVLENQNVGQNDLVENQNAPANQDFVGIDQVEAMADDSNDEPDEPDEPIVEAEEEFGTPEAEASPKSSPEKNKPFNCPNNCGSSFSHEYSLTRHIRDQCGPPRYKCPHCFYITRQPSNVYTHIKNKHPDERIYMIDTDMNQSCDEPGVVKACFSGEKFKTAYLGNCCDITAHAFEIPRSVPFIHTCSTCKSTFQRKSSLVRHIRYTCGSEQRFKCPYCYSRSNLASNVYKHVRCFHPEREVFTIDDKTTHHIHQSIMRPRENILKGLCLSAQLTIVQKSSAGREILADICDTSAMCNLDFNVRIVSIDSSQEDVLAEFDVSSRKMFPCPKCPSTFRQKPSLTRHIKYECSQPPRFSCPYCQHRSKKTSDIYVHVRRRHIDCQVFAIDIHGDPSDAVFQLCSLPWVEEKSTGRSSRKSRARFPCPRCQKSYTTKSAVTAHFKYDCGRPPRFQCPYCGRLSKKKFNIQDHIRHKHPSKSVVCGMYGYHYQEENFEVQFNPATGKFHCPKCNNGYGRRDNMVGHYRYQCGKSPRFQCVKHGGLHFQEENFWQKLEVQFNPVTGKFHCPKCNNGYGRRDNMVGHYRYECGKNPRFQCPYCSMCAKKSSNIYQHVRTVHPNEQVTLVRLY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -