Aque004235.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_032357855.1
- Location
- JAUELO010000032.1:849350-851646[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.00062 0.31 13.9 1.7 3 23 68 88 68 88 0.99 2 17 4.5e-06 0.0022 20.6 0.6 3 23 100 120 98 120 0.97 3 17 0.0095 4.7 10.2 0.7 2 23 126 147 125 147 0.97 4 17 5.9e-06 0.0029 20.3 2.6 1 23 181 203 181 203 0.98 5 17 1.5e-06 0.00074 22.2 0.1 2 23 210 231 209 231 0.97 6 17 8.9e-05 0.044 16.6 0.4 1 23 237 259 237 259 0.96 7 17 3.2e-05 0.016 18.0 0.2 1 23 266 288 266 288 0.93 8 17 4.1e-05 0.02 17.6 0.1 2 23 295 316 294 316 0.96 9 17 7.1e-05 0.035 16.9 1.3 1 23 322 344 322 344 0.98 10 17 0.00053 0.26 14.1 1.8 1 23 350 372 350 372 0.98 11 17 0.0031 1.6 11.7 4.4 1 23 378 400 378 400 0.97 12 17 0.00011 0.055 16.3 0.2 1 23 407 429 407 429 0.98 13 17 1.7e-05 0.0083 18.8 0.7 1 23 435 457 435 457 0.97 14 17 1e-06 0.0005 22.7 2.0 1 23 463 485 463 485 0.98 15 17 0.00041 0.2 14.5 0.8 2 23 542 563 541 563 0.94 16 17 2.7e-05 0.013 18.2 0.3 1 23 570 592 570 592 0.97 17 17 0.00066 0.33 13.8 4.1 1 23 605 627 605 627 0.98
Sequence Information
- Coding Sequence
- ATggaggaaagaTTAACTTCAAAAGATGAAGTTCCATGGAACAGTGTCTTTATTAAATCTGAGCCTGCCGAGTATGAGTTAAATGGAGAAGATAGTTCCAGAGAAGAAGAGAACAATCTCTCTAATATCAAGAATGAACATCCAATAACAGAGGCATGCACTTTGAAATTACCTATAATCAAACTTGAAAAACTGAACTGGTGTAATCTATGTCGACATGAATTCCAAACCGCTGACAGTTTAGAAATTCATATGAAAACCCACGTAAAAGTTACATCCATGATTAAACCCCTCGCTTGTGACGTTTGCTCCAAAGGCTATTCGAGGAAGCGTTACCTAATTAATCATATGAAGACTCACGAAAAATCGAGCCTAAAATGTGACAGCTGTGATCAACAGTTTCTTAGGTTATCTGCTCTTGTAAATCATAAGCGTAGTCATATTGGACAGCCCTTGGATATTAAGGAAAAATACGCTACATATAATTCTATGAAATTGATTTTACCTGGTAAGGAACTCGACAACGAAAATAGTAAGCCTTTTTCGTGTGACATTTGCTCCAAAAGCTTTGTGAAAAGGTCTTATCTAAATTTACACAGAAAAAGACACTGGTTTGCAAGGCCAATTCCATGTGACATTTGCGCAAAAAGGTTTATAACGAAGTTTGAGCTTATTGCTCACATGCGCACTCACACTGGAGAAAGGCCTTTCAAGTGCGACATTTGTAAGGCAaagttttctatcaaagaaagCTTGAGACGGCACGTAATTGCTCATATGAAAAATGATGGACCTTATGTATGTACAATATGTGCAAAAGGTTTTTCAACAGCCTACCTTTTGAAGAACCATATACCAACCCACTCAGAGCATAAACCTTTACAGTGTCCTATTTGTGAATACGGATTTATAAGAAGAACCGAATTAGCGTCGCACATGCTCTTCCACGAAAACGAAAAATCTTTCGAGTGTGAGGTTTGCTCTAAAACTTTTATAACGATTACCTTTCTGAAGCAGCatagaaaaattcatttagaGAGAATGCCTTACACGTGTGGAATTTGTGAGAGAAGATTTATCAAGAAACAGGTCTTCAATATGCATATGCGTTTTCATGATGGAAAAATGCCTTTTGAGTGcgactattgtaaaaaaaaattcgctcACCGTCACAGGATGGAGGATCATGTAATTTCTCACTGTGGAGATGACGGACTGTTCAAGTGTGAAATTTGTGGAGCAGGTTTTTCTATGCCCAAGATTTTAAAGCGGCATCTCcgattacatttaaattttaagccctTCGAATGTCAGCAATGCAAgaagaacttttcaaaaaaggCTGATTTAGCAGAACACATACTCCAGCACGCAAACAGCAGACCTTTTGTTTGTGAAGTTTGCGGCAAAGCTTTCACGAGAAAGTTTTATCTACGCTTACACAAGAAAAGACATTTACAAGATTCTTTTAAGCCCAGAGGGCCCTTTCTGCCTAAAAAGCCCATTCTGCCTAAAGAGCTCATTCTGCATAAAGAGCCCATGCAGCCTatgattcatgaaaaaaaatcgcCTACGCCACAGGTGGATACTCCTGTGCTtagtcaaactgaaaaaaaacctttGGAGTGTGAAATCTGtcataaaaaatttccagataGTTACAGGATGAAATTACACATGGTTGCTCATACGGGAGATGGCGGACCGCACAAGTGCTCAGTTTGTGGAAAAGGTTTTTCGATACCCTATGTTTTACAAATTCACATGCAAGgccacaaaaacaaaaaaccttgCGACAGTGTAAAAAGGCCTTTTGAGTGTGATGTTTGTAAGAAAAGATTTaggtttgacaaaaattttaaatcccacAAGATGAGTCATATAAAAGCTGAACCCAAAAACAGTCCTGATGAAAAGATAGGATTCGAGAAATCTGTTTCTCGTTCGGTACGTTTAAAGTCTGAAATTAAATGTGAAGTGCAAGATGAAAAGGATAATAATAGGGaaggtaaaaaagtaaaaattaaaaaaacgcctGAAAGTGGGAACTTCATCTTCCATTCTGTGAAAGAGGAACCTTTAGATCCATTAGCAATAGATGTCGAAAATATCAAGATAAAAgttgaagtaaattaa
- Protein Sequence
- MEERLTSKDEVPWNSVFIKSEPAEYELNGEDSSREEENNLSNIKNEHPITEACTLKLPIIKLEKLNWCNLCRHEFQTADSLEIHMKTHVKVTSMIKPLACDVCSKGYSRKRYLINHMKTHEKSSLKCDSCDQQFLRLSALVNHKRSHIGQPLDIKEKYATYNSMKLILPGKELDNENSKPFSCDICSKSFVKRSYLNLHRKRHWFARPIPCDICAKRFITKFELIAHMRTHTGERPFKCDICKAKFSIKESLRRHVIAHMKNDGPYVCTICAKGFSTAYLLKNHIPTHSEHKPLQCPICEYGFIRRTELASHMLFHENEKSFECEVCSKTFITITFLKQHRKIHLERMPYTCGICERRFIKKQVFNMHMRFHDGKMPFECDYCKKKFAHRHRMEDHVISHCGDDGLFKCEICGAGFSMPKILKRHLRLHLNFKPFECQQCKKNFSKKADLAEHILQHANSRPFVCEVCGKAFTRKFYLRLHKKRHLQDSFKPRGPFLPKKPILPKELILHKEPMQPMIHEKKSPTPQVDTPVLSQTEKKPLECEICHKKFPDSYRMKLHMVAHTGDGGPHKCSVCGKGFSIPYVLQIHMQGHKNKKPCDSVKRPFECDVCKKRFRFDKNFKSHKMSHIKAEPKNSPDEKIGFEKSVSRSVRLKSEIKCEVQDEKDNNREGKKVKIKKTPESGNFIFHSVKEEPLDPLAIDVENIKIKVEVN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00089803;
- 90% Identity
- -
- 80% Identity
- -