Basic Information

Insect: Amorpha juglandis
Gene Symbol: topi
Assembly: GCA_949126905.1
Location: OX421365.1:4018008-4023058[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.049 3.1 8.9 0.6 1 23 256 278 256 278 0.97

2 10 7 4.4e+02 2.1 1.7 2 23 305 327 304 327 0.91

3 10 0.00011 0.0068 17.2 0.3 1 23 350 372 350 372 0.98

4 10 0.012 0.74 10.8 0.4 3 23 378 399 377 399 0.96

5 10 0.0007 0.044 14.7 1.7 1 23 404 427 404 427 0.96

6 10 0.0026 0.16 12.9 1.0 2 23 434 456 433 456 0.90

7 10 2.9e-06 0.00018 22.1 3.8 1 23 463 486 463 486 0.98

8 10 0.00055 0.035 15.0 1.6 2 23 493 514 492 514 0.97

9 10 1.7e-05 0.0011 19.7 2.8 1 23 520 542 520 542 0.98

10 10 3.6e-05 0.0022 18.7 2.0 1 23 548 570 548 571 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.049	3.1	8.9	0.6	1	23	256	278	256	278	0.97
2	10	7	4.4e+02	2.1	1.7	2	23	305	327	304	327	0.91
3	10	0.00011	0.0068	17.2	0.3	1	23	350	372	350	372	0.98
4	10	0.012	0.74	10.8	0.4	3	23	378	399	377	399	0.96
5	10	0.0007	0.044	14.7	1.7	1	23	404	427	404	427	0.96
6	10	0.0026	0.16	12.9	1.0	2	23	434	456	433	456	0.90
7	10	2.9e-06	0.00018	22.1	3.8	1	23	463	486	463	486	0.98
8	10	0.00055	0.035	15.0	1.6	2	23	493	514	492	514	0.97
9	10	1.7e-05	0.0011	19.7	2.8	1	23	520	542	520	542	0.98
10	10	3.6e-05	0.0022	18.7	2.0	1	23	548	570	548	571	0.95

Sequence Information

Coding Sequence: ATGGAAGTACAAAGGACAATAGTAACTAACTACGGCGAGTGTCGATGTTGTCTCGCGAAGGGAAACCATCGCGACATATCCAAAGAATATTATTACAACGGAATACGAGAAGTTTTCATTGATATTTTCAtggaatgttttaatttatatTTATCCACAAACGAGAAACTGAGCACCTTGATATGTTCTTCATGTGTGTCTCGCCTGCGTGATGCAAGCACCTTCAGGATGATGGTTGTTAGCACTGAGAAACACCTGCTTGATGAACTCACCTCCCATGACCACAATTACACCATGTTTATTAATGTGCCAACAGTGGAGTCCGTCACGGTTCCTACAGATGTGAAGGTAGAACAACAATTTGAAGTAAAGTCGGAAGACGATGATGAAATTAATTTCGATCTCAGCTACCCGGATGGGTCAGAGAACGCGGAGGAAGATAGGTTTGTGGAGGGCGAGCGAGTGTTCCTCAGCAGGTTCAGTGACGGCGCGCTGTTTCCGTCGCCTCGTCCGTCGCCTCGCCCGCTGCCGACGCGCGCCGCCCTGCGCGGACACTGCCCCATGTTCGTCAAACATCTCGACGCTCTTAAAGGAAAGAACATCACAGCAAAGTCGATAGAAAAACTGATCCTAGGTTTAGAGAAGCGGTTGAAACCAGAGAAAAACAATTTGCACATCAAAGAAAAAATGGCTCACACAATCAACGCTTGTACAATATTCGAGTATTCCACCGCTACAGCCTTCAAGACTAAGACGAAGTCTGGATATCCGTGCTTCTATTGCAGAGAAATTTTCGACACCATGGATATATTGCGGGAACACCAAAAACAGCACCCGAAATCGTCATTATTCAAACTATTCAGCAAATATACGGCAGATGCGCTTGTTGTGTACGCTGACGTCACAGATCTCTGTTGCAGCATCTGTTGTAAATCGATTCCAAGTATTAATGAACTGAAGAGTCATTTAGCAAATGTGCAcgggaaaaaaatatacacggaTTTCGAAGATAGAGTCATACCTTTTAAATTGACTGGCTACAGCGATTTCGAGTGCCAAATATGCGGTTTTAACTTTGAGACGTTTGGCTCCATTGAGAAGCATATGAATGTTCACTACAGGAATAATATCTGCGAACAATGCGGGGCGGGATTTGTCACGATGCACCGGCTGAAAATACATTACTCCACTGTACATAAAGAAGGTTCATATCCAtgcaaaatatgtaaaaaagtcTACTCTAattacaacaaatataaaatgcaTTTTAATGTGGTGCATAAAATGGTGAAAAAGAACAAATGTCCCAAATGTCCGGAGAGTTTCACAGACTACTTCACGAGACAGCGGCACTTGGTGGAGAAGCACGGCGTGACGCCCGTTCTGTATCGGTGCAAAGTGTGCGACAGAGCATTTAGCAGACGATTTGCGCTCACTGACCACATGAAGAGATGCCATTTGGAAGAAAAGGACATCCAGTGTCTACAATGCCCGTACATGTGCTACACGAAGCAGGAGTTACGCGCCCACATGTTGAAACATGGCGGGGAGAAGTGTCACGAATGTACAGTGTGTAAGAAGTCGTACGTACGCCTGAAGACGTTGAAAGAGCACATGAAGATACACAATAATGACAGGAGGTTTGCATGCGCTGAGTGTGGACAGGCGTTCGTGCAGAAGTGTAGCTTAAAAGGCCATATAAAGACGCATCATTCGAAATAA
Protein Sequence: MEVQRTIVTNYGECRCCLAKGNHRDISKEYYYNGIREVFIDIFMECFNLYLSTNEKLSTLICSSCVSRLRDASTFRMMVVSTEKHLLDELTSHDHNYTMFINVPTVESVTVPTDVKVEQQFEVKSEDDDEINFDLSYPDGSENAEEDRFVEGERVFLSRFSDGALFPSPRPSPRPLPTRAALRGHCPMFVKHLDALKGKNITAKSIEKLILGLEKRLKPEKNNLHIKEKMAHTINACTIFEYSTATAFKTKTKSGYPCFYCREIFDTMDILREHQKQHPKSSLFKLFSKYTADALVVYADVTDLCCSICCKSIPSINELKSHLANVHGKKIYTDFEDRVIPFKLTGYSDFECQICGFNFETFGSIEKHMNVHYRNNICEQCGAGFVTMHRLKIHYSTVHKEGSYPCKICKKVYSNYNKYKMHFNVVHKMVKKNKCPKCPESFTDYFTRQRHLVEKHGVTPVLYRCKVCDRAFSRRFALTDHMKRCHLEEKDIQCLQCPYMCYTKQELRAHMLKHGGEKCHECTVCKKSYVRLKTLKEHMKIHNNDRRFACAECGQAFVQKCSLKGHIKTHHSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00858864;
90% Identity: iTF_01010646;
80% Identity: -