Basic Information

Insect: Amiota mariae
Gene Symbol: PRDM1
Assembly: GCA_035041805.1
Location: JAWNKV010000332.1:5469401-5474476[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3.4e-05 0.0045 18.3 2.5 1 23 981 1003 981 1003 0.99

2 5 1e-05 0.0013 20.0 5.1 1 23 1009 1031 1009 1031 0.98

3 5 2.2e-06 0.00028 22.1 4.3 1 23 1037 1059 1037 1059 0.98

4 5 0.00072 0.093 14.2 2.4 1 23 1065 1087 1065 1087 0.97

5 5 0.00012 0.016 16.6 0.1 1 22 1093 1114 1093 1114 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3.4e-05	0.0045	18.3	2.5	1	23	981	1003	981	1003	0.99
2	5	1e-05	0.0013	20.0	5.1	1	23	1009	1031	1009	1031	0.98
3	5	2.2e-06	0.00028	22.1	4.3	1	23	1037	1059	1037	1059	0.98
4	5	0.00072	0.093	14.2	2.4	1	23	1065	1087	1065	1087	0.97
5	5	0.00012	0.016	16.6	0.1	1	22	1093	1114	1093	1114	0.96

Sequence Information

Coding Sequence: atGCAtggacatcatcatcaacaacatcagcagcaacagcaacaacaacaacaacatcaacaacacctACAACAGacacatcaccatcatcagcaacaacatcatatgcaacagcaacatcaacatataCAACaccatcagcaacagcaacaacaacagcaacttcatcatcatcaacaacagcaactacatcagcaacagcagttgCAGCAGctgcaactgcaacaacagcaacatcaagaACGTGCTACAAAGTTAAGtaacaatagtagtagtaatagtagtagtagtagcagcagcagcaacaacatgtgTACAACGCAACCACCGCCTACAAATGCCACCATTCCCGCCACAAAGCCACGCAGTCGCAGTCCAACGCCGGACGGTACACGCGACTATGATGTTACACGTATGCGTGAAGCGGATTTCGAGAATCTGGCAGTTTATCTTGTGCCTGATGTACAATGCGAACGTGGCATACCAAATCGTGCTGATAAAACGTTGCCACGTAGTCTAACACTAAAGCCATCGATGGTATTCTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGTGTAGGCGTCATACCGCGCGGTACGCGCTTTGGCCCATTTGAAGGCATTTCAACTTCAGATTATCCAAATGATAAGAATAAGGCGCGCTATTTCTGGCGGGTGCAGGGCACACGCCACATAACCTATGGGAATATTAAGATCTTTAAAGACGATGATTACTATTATCTGGATGGTTCTGATCGTTCTCAATCCAATTGGATGCGTTATGTTGCATCCGCTTATAGTTTATCTGTCATGAATCTGGTAGCGTGCCAGCATCAGGATAACATATACTTCTATACCACCCGCGATATTATGCCAAATGAAGAGCTTATGGTCTGGTACTGCAAGGATTTCGCTAGTCGACTGGGTTACGATGTCGATCCAGAGACTACGATATTCGGTGCCTGTAAGCAGGCATCTGAACATGCACCAAATGAGGctgaaattgatgatgatggcaacaTCGTAGGCgacgaagatgatgaagagatGGAACATGATGCTGAAGTGGCGGCAACATGTAAGAAACCATATACATGTATGCCAGCTCCAGAAATACCACCTGAGGTCGCCTATAATCACATTACGTATGTGATGGGCCTACATATGCCACCGACAGCGAATACCACAACAACTTCATCAGCGTCGTCGACAGGGTCAGCAACTGGTAGCTGCTGCAGACGTGGTAGTTCACAATCCCCTGTGTCTGTGACGAGCTCAGCTTGTACAACAGCACATCCGCATATTCAACATGCTGGCCGTCATCATCTGCATCAGAATGTATTACAGTTGAAACaagaaccaacaacaacaacaacaacaacaacatccacATCGTCATCGTCCTCAGTCATTATGCATGATCGTTCGCCTGCCGGTTGTAGTGATGGTTGCAAGGACAGTGCTGGCTCACCTATGTCACACAAGGATGCGGCTGTGTATGAACATCAGCTGACGCCCAACGATGGCAGTGTTCGCTCGGTGCGATCTGATGAAGGTTATCACAGCAATGAGTGCCATGAGGATGGACTCACACCACCAGAGGATTCCAGCGATAGCGAAAGTGAACACAACTATGTGTTGGATTGTTCAAAGAAGACCATTGCCCCCAAGGAGACTGTTATTGCGCAGGCCCAGAAGGTATGCCCCATGCCAGCAGCACCTGCCGTAGCCCCTGCAGTGGTGACAACAGTGGATTGCGATAAGAATGAGTATCGCAAGTTCAAGGTGAAGATGCCGCCAAAGTATGAGTTCAAGAACagcaaaaattgtattaaagcAATGGATGAGGCAATCGTTGTGCGTGAGACAGTTGCAACTACTGTGGTCGAAGATGAGGAGCTGCATGAATTGCgtgctgcagctgctgcagcGGCTGCCGCAGCAGCTCAGAGTAATGAAGATATTGCCTGTTCGACGACCACGAACGATGAGCATATGGATGTGGATCAACGATTACCACAAACGATTTCCTCAATATCGACAAGTCAACCTGCTACTAGCACAGTGATTGTACTTGAGCATGGCATTAATTCCTCCACGCGTGAGACACGTACAATCGTCCCTCTAAGTAAGCCTTATTATGAGTCTGATTTAGGCAATTCTGCTGGTCCACAAGGGGCCACTGCCTATGTACGCTTCACACAGCCATCAAGTATATTGGAAACAATACTGACGAGTCAGCATCGTTTAgaggcagcagcagctgcagcaaaCGCTTGTCGACAGGCAAACTCTGCAACACCACCTCCAACATCTCCCACAGAATTGGCGTACTCTTATAAGAAATCACAAAGGTATGGCAACGCCGTCAGCCCTGATTCCAGTTCCAATTTGGGCCAATCGCAAGAATCAGTTGCGCATATCAGCGAACCTGATTTGGTTGCCACGCGGGGTCTTATTAAGGGTGAATGCTCACCGCCACCACAGATGCAGCAGCATGTGATCTTTTCGCCTGCGCACCGAACAACGCACAATGTTTACGTGGATCAGGGACCACAATCACCCACATACGCTGCCTACTCTCCCTACACGAATGGTAGTGGTTCGGCACAAGTACTGCATGCAGCAACTTCCACATTTCACTCACCACCACACAGCTCGCATTCACCTTTTGATCGCCAATCGAATGCTTCAAGCGGTTCCACATCCAACCTGCATTTGCTGCAGAGCAGTACACAAATGCTCAATCATCCTTTGATGCAGCCACTCACTCCTCTCCAACGTCTCTCGCCATTACGCATTTCACCTCCGAGCAGCCTCAGTCCGGATGGTAATTCCTGCCCTCGTAGTGGTAGCCCACTCAGTCCCAACTCGCTCGCCTCGCGTGGCTACCGTTCATTGCCCTATCCACTCAAAAAGAAAGATGGGAAAATGCACTATGAGTGCAACGTTTGTTGCAAGACATTTGGTCAATTGAGTAACCTTAAAGTACATCTGCGTACTCATTCCGGTGAACGTCCATTCAAGTGTAATGTCTGCACGAAGAGCTTCACTCAGCTGGCGCATCTTCAGAAGCATCATCTCGTACACACTGGTGAGAAACCGCATCAGTGTGACATCTGCAAGAAACGTTTCTCCTCCACTTCGAATCTGAAGACTCATCTGCGCCTGCATAGCGGCCAGAAGCCGTACGCCTGCGATCTCTGTCCTCAAAAGTTCACCCAGTTCGTGCATCTTAAGCTACACAAGCGCCTCCACACAAATGATCGGCCTTATGTATGCCAGGGATGTGACAAGAAGTACATAAGCGCTTCAGGGCTACGCACACACTGGAAAACAACTAGTTGCAAGCCAAACAATCTGGAGGAAGAACTTGCCATGGCCGCCGCTGCGACTTCTGAATGTTTGGATAAAGATTTACCTGAGCCAGATTCACGCGAGGCCTTTGAACAACTGCAGCAACATATACATCCAAATATGCGGCACATTGGCGGCGGTGGCCATCATTCGCCACCACGTCTAATAGCATTAAGCGCGCAAAACACGCCTCCACCCCCGCCACCACATCATACACATCCCCACCACCACCTGTCACATCCCCATCATCAACCAGCACCTCCTTCTACGCAGCCTCAACAACATCCACATGCTCATATGTTGATGCAACACAACGGTGGCGCTCATAATGGGCCTTCAATGCTACTCACGACGACAAATCAACTTcatcaccagcagcaacaacaacaacaacaacaacaagtgcgTCAGCCTCATATGCAATCATCGTTAAAGCCAATGAAGCCACACTTACATGTAGCGCCATCAGCATCCGCTCCACCACCGCCACCCCAAAATCAGAACAATGAATCCTCTAGCCCCTACATGCATGCACAACATGTACAAAATCAGGAAGGTCGACCATCGGTTATTGAGTCGAATCAGCCAATGATTATTGAGTGCACGTAG
Protein Sequence: MHGHHHQQHQQQQQQQQQHQQHLQQTHHHHQQQHHMQQQHQHIQHHQQQQQQQQLHHHQQQQLHQQQQLQQLQLQQQQHQERATKLSNNSSSNSSSSSSSSNNMCTTQPPPTNATIPATKPRSRSPTPDGTRDYDVTRMREADFENLAVYLVPDVQCERGIPNRADKTLPRSLTLKPSMVFSTPNVKTEGVWSVGVIPRGTRFGPFEGISTSDYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHQDNIYFYTTRDIMPNEELMVWYCKDFASRLGYDVDPETTIFGACKQASEHAPNEAEIDDDGNIVGDEDDEEMEHDAEVAATCKKPYTCMPAPEIPPEVAYNHITYVMGLHMPPTANTTTTSSASSTGSATGSCCRRGSSQSPVSVTSSACTTAHPHIQHAGRHHLHQNVLQLKQEPTTTTTTTTSTSSSSSVIMHDRSPAGCSDGCKDSAGSPMSHKDAAVYEHQLTPNDGSVRSVRSDEGYHSNECHEDGLTPPEDSSDSESEHNYVLDCSKKTIAPKETVIAQAQKVCPMPAAPAVAPAVVTTVDCDKNEYRKFKVKMPPKYEFKNSKNCIKAMDEAIVVRETVATTVVEDEELHELRAAAAAAAAAAAQSNEDIACSTTTNDEHMDVDQRLPQTISSISTSQPATSTVIVLEHGINSSTRETRTIVPLSKPYYESDLGNSAGPQGATAYVRFTQPSSILETILTSQHRLEAAAAAANACRQANSATPPPTSPTELAYSYKKSQRYGNAVSPDSSSNLGQSQESVAHISEPDLVATRGLIKGECSPPPQMQQHVIFSPAHRTTHNVYVDQGPQSPTYAAYSPYTNGSGSAQVLHAATSTFHSPPHSSHSPFDRQSNASSGSTSNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPDSREAFEQLQQHIHPNMRHIGGGGHHSPPRLIALSAQNTPPPPPPHHTHPHHHLSHPHHQPAPPSTQPQQHPHAHMLMQHNGGAHNGPSMLLTTTNQLHHQQQQQQQQQQVRQPHMQSSLKPMKPHLHVAPSASAPPPPPQNQNNESSSPYMHAQHVQNQEGRPSVIESNQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00063152;
90% Identity: iTF_00063152; iTF_00061545;
80% Identity: -