Basic Information

Insect: Amiota mariae
Gene Symbol: ush
Assembly: GCA_035041805.1
Location: JAWNKV010000370.1:4996870-5003094[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0031 0.4 12.2 0.0 1 20 266 285 266 287 0.93

2 9 0.00035 0.045 15.2 0.8 1 23 344 366 344 366 0.98

3 9 0.058 7.6 8.2 1.0 2 21 405 424 405 425 0.92

4 9 0.06 7.8 8.1 2.9 2 21 828 847 827 848 0.93

5 9 0.011 1.4 10.4 0.0 3 21 907 925 905 926 0.91

6 9 0.0047 0.61 11.6 0.1 2 23 1029 1050 1028 1050 0.98

7 9 0.028 3.6 9.2 1.2 1 23 1056 1078 1056 1078 0.99

8 9 0.0018 0.23 12.9 0.7 1 23 1143 1166 1143 1166 0.96

9 9 0.99 1.3e+02 4.3 0.6 2 20 1303 1321 1302 1323 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0031	0.4	12.2	0.0	1	20	266	285	266	287	0.93
2	9	0.00035	0.045	15.2	0.8	1	23	344	366	344	366	0.98
3	9	0.058	7.6	8.2	1.0	2	21	405	424	405	425	0.92
4	9	0.06	7.8	8.1	2.9	2	21	828	847	827	848	0.93
5	9	0.011	1.4	10.4	0.0	3	21	907	925	905	926	0.91
6	9	0.0047	0.61	11.6	0.1	2	23	1029	1050	1028	1050	0.98
7	9	0.028	3.6	9.2	1.2	1	23	1056	1078	1056	1078	0.99
8	9	0.0018	0.23	12.9	0.7	1	23	1143	1166	1143	1166	0.96
9	9	0.99	1.3e+02	4.3	0.6	2	20	1303	1321	1302	1323	0.90

Sequence Information

Coding Sequence: ATGGTAGTTTGCAGTATATTGAAGCAGGTTGATGAGATTTCTTATAAAGTATatTCCAAAGATTTAAACTCACACGAATTGAGCGAAGAGAAACTGGAGTTGGATCCAGAGACAACATCTTCGTCGAATGCAAACCAAACAGAGACTGACAACGCTAATGAAATGAGCGAACAACATGAAGAATCTGacgaccatcatcatcatcctcactCTGAGGCATCATTGTCATCACCGCGTTCAAGCATAAGTCATGGACGCACGGATCATGATAAAAGCGATGTTGATGAACAAGCATCAGAACCGGACAAAGGTTTAGATGATTCGAAAGTGTCGTCTATGTCCCCTATGATGCAAATTCCTCAAGATTGTATTAAAGTAGAAGAGCCTTCAGAAATCGACATGCACTTAGAACAACTAGAGAGGCATATATCACCATCACCAGCCATGCTCCGGTTGGCATCATCCACAACTTCATCGACGCCCAGTCCTGTGGCAACTCCCTCGCCAGCACATTCTGATGTTGTCGATGCAGATCGGGCAAGCGGCACACCGCCAGCGTCAATGACCATTATGCCAAAATTACGTTTGAATGCTTTGCTTGCTTCGGATCCTGCCCTGAAACCGGATGCCAAAGACCTCAAAAAGCTGCATGAAGAAGCGCAAGCCCAGACATCCGCATTGCCACCTCTCCCAGCGTTAACCAAACAGGAGCCGCTTTCAATCGATGGCGGTTCACATCTGTTAAAGCAAACCAATACATCAGCGGAAGTATCACAAACGCCACGGATGAAAGTGTTCATGTGTGAACCCTGCGGCATTGGCTTTAGCTCACCCTCAACACTACAAGCACATCAAGCCTACTATTGTTCACATCGGAACAAGGATGTCGATGATGAACTCAGTGGTGCCAATCAAGATAAATCTGGCACAGCATCAACCACTGGTGTTTCTCCAGCCGGCGGTGGCACTAATAATGTACAGAATTCCAATAGTGAGCCACCGGCTAAAGTGCCACGACTTGGCAAGCAATACGCTTGCACACAGTGTTCCTATAGCGCCGACAAAAAGGTCTCATTGAATCGTCATATGCGCATGCATCAAACATCACCTGCGACACCCGCCTCCAGTTTGGTTACGGCGGCCAATGGGGGAGGCGCAACTGCCAGTGTCGGCGCAAACTATGAAGATAGCACTAGTCAACAAATAGATCGATACTGCAGTGATTGCGATATAAGATTTAATAATGTGAAAACCTATCGGGCGCATAAGCAACATTATTGCAGCTCCCGACGGAATGATGGCCAGCTCACTCCTAAGTTGGAGGCAGGCACCTCAAGTGGAACTAGTGTACCCACTACAAGCACAGTGAAATCTACGCCTTTGGGTCACGCTGGTGGCCATAGTCCACAGGCTCGCAACAACAAGACACCTACACCAGCCATGGTTGCAGCCGCAGCcgcagcagctgcagcagcagcagcatctcTACAACCACCACCGCAGCCATACTTTGCATTGCCCACCAGTCCCATAATTATTATACCATATTCACTGATACGCGCTGCCAGCCTCATACCAGGTCCACTTACTACTTCTACGGCGGGTATTGTTAACCCGGATACCACATGTTTTACCCTGGACAATGGCGCTCTCAAACCTCTGGCCACTGCTCTAAATATTAATGCCTTAAGCAATGCAAATCCTCAGGTACCATTACCTCACAACAGTGCAAGCAATCAAATACCCAATGTTCCATCTGCTGAGTCTGTTACAATGTTACCAGAGAAGAATGCCACTGGTCGTCATATGGAAACTAATGATGCCATACCAACTAAACGTAAAGAGTCTGGCACACGTGAATCAGCACCTTTAGATCTCTCACTACGTCGCTCGCCGATTGTAGCCATACTTCAGCGGCAGCGTCTAGAAATGGATACCTTACTTGAGGCTAGTAAGGAGAACCTTTCGCTGCATGAAAGTGGCAGCGTTACTCCCGAACAAATCGTGTGTGCGCCCTCCCTGCCCAATAGTCCCTCGATGAGTCCTTCTCCAAAGCGCCGTGCTATAAGTCCTCGCAGTTCTGGAGCCGGTAGCACCTCTTCCATGTCACCGCCGGCCAATGTTACAGTTGCCAATTTCGCAGCTACCGCTGGACTTTTGGATAACTTGCCATTGCGTTCAATGCTGCCAGCTGATTTGGCACTAAAGCTGTCTGAAACGAATATCATGAATCCTTTGTTGGCTAAACAAAACCTCGAATTAGCACTCAAGTTGTCGgcagctgctgcagctgcagcCAATTCGGCCTCACCTGCTCTAGCCGCGGCTGCAGCTGCCGGCACAGCCAGTCCAGCAGAATTGGCTGCAGCAGCCGTTGTGGCCGCTGGCAAATTGGGCTTGGGAGTGACGACTAACGCTGCCGTGGCGGCCGCAGCATCGAACTCACAGCAGCCACAAATCTATGTGAAACAAGGAGTGTCCAAATGCAAGGAATGCAACATTGTCTTTTGCAAATATGAAAACTACTTGGCGCACAAGCAACACTATTGCTCGGCACGTAATCAAGAGACTTCTATTGAAGGTGGTACCACTAGTGGCACAGGAGGAAGCACTGGCAGTGGTGACAATAAAGTCTCAATCACACCACCAATGTCCGGCGGAGGTAACGCCTCTGCTGCTGTAGAGTCCGCACCACCGGTCGCCTATCAACAGTTGATTTGTGCTGCTTGCGGCATTAAATACACGTCGCTGGACAATTTGCGTGCTCACCAAAACTACTATTGTCCTAAGGGAGGCGGTGCAGCTGCCGCCGCAGCAAACAATGCGAATTCCGCCACAACAGCGGCAGCAACAGTAGCCGCAGTTGCCGCAGCTGTCGAAGCAGGAACGctCTCATTGCCTAAGGAGAAgtgcaacaaatgcaaaacgATTCATGAAATTGGCTTACCATGTCCACCACCCAGCGCTACTGCGCTCCAGCATCAGCATTTGATTGCTAACAGTGAACGAGCAACGAACaaccatcatcagcaacaacaacaacaacatcagcagcagcagcagtctCAACACAGTAATGTCAATAAGTGTCCCGTGTGCGGTGTGGTTAGCCAGACCGCAGCCCAAGCACGCAAACACATGGAAACACATGGCACCGTCAAAGCATTCCGTTGTACTATTTGCCTGTACAAGGGCAACACTTTGCGAGGCATGCGTACCCACATTCGAACGCATTTCGATAAGAAAACCAGCGATGTTAATGAAGAACACTACATGACATGCATTTTCGAGGAGGATAACAACATGGAACTGGCATCTGCGGCACTGTCTTTGCAACAACAGGAACAGgctcaacaacagcaacaacagcagcagcaacaacaggcACAGGAACTGCAACTTCAGGCTCAAGCCCAACAGCAATTATATAACTGTGACAACTGTAACTATGCCTCAACCTACAAGGGCAATGTGCTACGTCATATGAAACTCATGCATCCACATATCGCCATAAACTCTCCATCAATTTCACCCGAAACTGGCACTGGTGACTATGAGTCCAATGACATAACCTCGTCAATTAATGGCGAGACTAATATTAACAGCTTCACAATCAAGTTGGAGCCCCTGGACCACCACATAACAACCAATCAAATCTCGAATCTTAGCCACATACACGACAATAACAACTCACCACCGACACCGACACCCACAGCGACAACGCCTCATGTTCAACCAGATCTAGTGATGCCACACATCAAATCTGAACCAATGGATATAGCAATCGACAATTCAATTACACCAGCATTGCCACCGCCTGCTTTAACACCCACAGCTATGACCTCACCATTGGGAACAGCAGTTGGAGCTGCCATGGCAGTGGCAGCATCTGATGCCCTCAAGAAATACTGCTCCACCTGTgacatttcattcaatttcgtGAAAACCTACTTGGCTCACAAACAATTCTATTGCAAAAGTAAAGTGCTGCGTCCCGAAGTACATGAGAGCCCAAGCCCGAATGcagcgacgacgacgacgactccTATGCCCATACCATCGCCCAATGAATTGTTATTGATGCAAAAGAACAAGGAGAACATGCAACAGGAAGCGGCCATTTGA
Protein Sequence: MVVCSILKQVDEISYKVYSKDLNSHELSEEKLELDPETTSSSNANQTETDNANEMSEQHEESDDHHHHPHSEASLSSPRSSISHGRTDHDKSDVDEQASEPDKGLDDSKVSSMSPMMQIPQDCIKVEEPSEIDMHLEQLERHISPSPAMLRLASSTTSSTPSPVATPSPAHSDVVDADRASGTPPASMTIMPKLRLNALLASDPALKPDAKDLKKLHEEAQAQTSALPPLPALTKQEPLSIDGGSHLLKQTNTSAEVSQTPRMKVFMCEPCGIGFSSPSTLQAHQAYYCSHRNKDVDDELSGANQDKSGTASTTGVSPAGGGTNNVQNSNSEPPAKVPRLGKQYACTQCSYSADKKVSLNRHMRMHQTSPATPASSLVTAANGGGATASVGANYEDSTSQQIDRYCSDCDIRFNNVKTYRAHKQHYCSSRRNDGQLTPKLEAGTSSGTSVPTTSTVKSTPLGHAGGHSPQARNNKTPTPAMVAAAAAAAAAAAASLQPPPQPYFALPTSPIIIIPYSLIRAASLIPGPLTTSTAGIVNPDTTCFTLDNGALKPLATALNINALSNANPQVPLPHNSASNQIPNVPSAESVTMLPEKNATGRHMETNDAIPTKRKESGTRESAPLDLSLRRSPIVAILQRQRLEMDTLLEASKENLSLHESGSVTPEQIVCAPSLPNSPSMSPSPKRRAISPRSSGAGSTSSMSPPANVTVANFAATAGLLDNLPLRSMLPADLALKLSETNIMNPLLAKQNLELALKLSAAAAAAANSASPALAAAAAAGTASPAELAAAAVVAAGKLGLGVTTNAAVAAAASNSQQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQETSIEGGTTSGTGGSTGSGDNKVSITPPMSGGGNASAAVESAPPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGGAAAAAANNANSATTAAATVAAVAAAVEAGTLSLPKEKCNKCKTIHEIGLPCPPPSATALQHQHLIANSERATNNHHQQQQQQHQQQQQSQHSNVNKCPVCGVVSQTAAQARKHMETHGTVKAFRCTICLYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDNNMELASAALSLQQQEQAQQQQQQQQQQQAQELQLQAQAQQQLYNCDNCNYASTYKGNVLRHMKLMHPHIAINSPSISPETGTGDYESNDITSSINGETNINSFTIKLEPLDHHITTNQISNLSHIHDNNNSPPTPTPTATTPHVQPDLVMPHIKSEPMDIAIDNSITPALPPPALTPTAMTSPLGTAVGAAMAVAASDALKKYCSTCDISFNFVKTYLAHKQFYCKSKVLRPEVHESPSPNAATTTTTPMPIPSPNELLLMQKNKENMQQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00063106;
90% Identity: iTF_00063106;
80% Identity: -