Basic Information

Insect: Amiota communis
Gene Symbol: ush
Assembly: GCA_037043315.1
Location: JBAMAV010001536.1:2450373-2458888[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.016 1.9 9.9 0.0 1 20 282 301 282 303 0.90

2 9 0.00035 0.042 15.2 0.8 1 23 360 382 360 382 0.98

3 9 0.059 7.1 8.2 1.0 2 21 421 440 421 441 0.92

4 9 0.061 7.3 8.1 2.9 2 21 844 863 843 864 0.93

5 9 0.011 1.3 10.4 0.0 3 21 925 943 923 944 0.91

6 9 0.0048 0.57 11.6 0.1 2 23 1043 1064 1042 1064 0.98

7 9 0.029 3.4 9.1 1.2 1 23 1070 1092 1070 1092 0.99

8 9 0.0007 0.083 14.2 0.4 1 23 1156 1179 1156 1179 0.96

9 9 0.88 1e+02 4.5 0.6 2 20 1313 1331 1312 1333 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.016	1.9	9.9	0.0	1	20	282	301	282	303	0.90
2	9	0.00035	0.042	15.2	0.8	1	23	360	382	360	382	0.98
3	9	0.059	7.1	8.2	1.0	2	21	421	440	421	441	0.92
4	9	0.061	7.3	8.1	2.9	2	21	844	863	843	864	0.93
5	9	0.011	1.3	10.4	0.0	3	21	925	943	923	944	0.91
6	9	0.0048	0.57	11.6	0.1	2	23	1043	1064	1042	1064	0.98
7	9	0.029	3.4	9.1	1.2	1	23	1070	1092	1070	1092	0.99
8	9	0.0007	0.083	14.2	0.4	1	23	1156	1179	1156	1179	0.96
9	9	0.88	1e+02	4.5	0.6	2	20	1313	1331	1312	1333	0.90

Sequence Information

Coding Sequence: ATGGTAAGCGCAGAAATCCAGGGGAAATGGTGGGATAAAGATAGGAGGGAAGGCAGTAAAGAAAGTGTAGATTATAGTGAACTAGCAGAGCAGAATGAAGATTCCAAAGATTTAAGCGCACACGAATTGAGCGAAGAGAAACTGGAGTTGGATCCAGAGACGACATCATCGTCGAATGCAAACCAAACAGAGACTGACAACGCTAACGAAATGAGCGAGCAACATGAAGAATCtgaagatcatcatcatcatcactctGAGGCATCATTGTCATCACCGCGATCAAGCATAAGTCATGAGCGCACGGATCATGACAAAAGCGATGGTGATGAACAAGCAACAGAACCGGACAAAGGCTTGGATGACTGCAAAACGACATCAATGTCCCCCATGATGAAAATTTCCCAAGAATGTATTAAAATAGAAGAGCCTGCAGAAATTGACATACACCTAGAACAATTAGAGAGATATatatcaccaccaccaccagcaatGCTCCGGTTAGCATCATCCACAACTTCGACTACGCCCAGTCCAGTGGCAACTCCTTCGCCAGCACATTCCGATGCTGCCGATGTAGAACGAGCAAGCACCACACCACCTACGTCAACACCTATTATGCCAAAATTACGTTTGAATGCATTGCTTGCTTCGGATCCTGCTCTGAAACCGGATGCCAAAGACCTTAAAAAACTGCATGAAGAGGCGCAAGCCCACACATCCGCGTTACCACCGCCACCAGCTTTAACCAAACAGGAGCCACTTTCAAACGATGGCAGTCCACATCTGTTAAAGCAAAGCAAGACAGCAACAGAAGTATCACAAACGCCACGAATGAAAGTGTTCATGTGTGTTCCCTGCGGCATTGGCTTTAGTTCACCCTCAACACTAGAAGCACATCAAGCCTACTATTGTTCACATCGGAACAAGGATGTCGATGATGAACACAGTGGTGCCAATCAAGATAAAACTGGGACCGCATCAACCGCTGGTGCTTCTCCATCCGGCGTTGGCACTAATAATGTACAGAGTTCCAATAGTGAACCACCGGCAAAAGTCCCACGTCTTGGCAAGCAATACGCTTGCACACAGTGTTCCTATAGCGCCGACAAAAAGGTCTCATTAAATCGTCATATGCGCATGCATCAGACATCTCCAGCGACACCAGCTTCCAGTTTGGTTACGGCAGCCAACGGGGGAGGAACGAGTGCCAGTGTCGGCTCAAACTATGAAGATAGCACTAGTCAACAAATAGATCGATACTGCAGTGATTGCGATATCCGATTTAATAATGTGAAAACCTATCGGGCGCATAAGCAACATTATTGCAGCTCCCGACGGAATGATGGCCAGCTCACTCCTAAGTTGGAGACAGGCACCTCAGGTGGAATAAGTGTACCCACTACAAGTACAGTGAAATCTACGCCTTTGGGACACGCTAGTGGTCATAGTCCACAAGCTAGGAACAACAAGACCCCAACACCAGCCATGGtggcagctgcagcagcagcagctgcagcgGCTGCTGCATCTCTACAACCGCCACCGCAGCCATACTTTGCATTACCCACCAGTCCCATAATCATTGTACCATATTCGCTAATACGCGCTGCCAGCCTCATACCAGGACCACTTACTACTTCCACGGCAGGTATTGTTAATCCGGATACCACGTGCTTTACCCTGGATAATGGCGCTCTCAAACCTCTGGCGACTGCTTTAAATATTAATGCCCTGAGCAATGCAAATCCTCAGGTACCATTACCTCACAATAGTGCAAGCAATCAAATAGCCAATGTTCCATCTGCCGAGTCAGTTACAATGTTGACAGAGAAGAATGTCAGTGGTCGTCATATGGAAACTAATGATGCCATACCAACTAAACGAAAAGAGTCTGGCACACGTGAATCAGCACCTTTAGATCTCTCACTACGTCGCTCGCCAATTGTAGCCATGCTTCAGCGGCAGCGTCTAGAAATGGATACCTTACTTGAGGCTGGTAAGGAGAACCTTTCGTTGGATGAAAGTGGTAGCGTAACGCCCGAACAGATCGTTTGTGCACCCTCCCTGCCCAGCAGTCCCTCGATGAGTCCTTCACCAAAGCGTCGTACTATCAGTCCCCGCAGTTCTGGAGCCGGAAGCACTTCTTCCATGTCACCGCCGGCCAATGTTACAGTTGCCAATTTTGCAGCTACCGCTGGACTCCTGGATAATTTGCCTTTGCGTTCAATGCTGCCAGCTGATTTGGCCCTAAAGCTCTCTGAAACGAATATCATGAATCCACTGTTGGCTAAACAAAACCTCGAATTGGCACTCAAGTTGTcagcagctgctgcagctgcaGCCAATTCGGCCTCACCTGCTCTAGCTGCGGCTGCAGCTGCCGGTACAGCCAGTCCAGCAGAGTTGGCTGCAGCAGCCGTTGTGGCCGCTGGCAAATTGGGCTTGGGAGTGGCACCCAATACTGCAGTGGCTTCTGCTGCATCGAGCTCACAGCAGCCACAAATCTATGTGAAACAAGGTGTGTCCAAATGCAAGGAATGCAACATTGTCTTTTGCAAATATGAAAACTACTTAGCGCACAAGCAACACTATTGCTCGGCACGTAATCAAGAGGGTTCTATTGAAGGTGGAACCACTAGTGGGGGAGGAGGCAGCACTGGCAGTGGCGACATTAAAGTCTCAATCACACCACCAATGTCCGGCGGAGCCGTTGGTaacgctgctgctgctgtagaATCCACACCACCGGTCGCTTATCAACAATTGATTTGTGCTGCTTGCGGCATTAAGTATACGTCACTGGATAATTTACGTGCTCACCAGAACTACTATTGTCCCAAAGGGGGCGGTGCTGCTGCCGCCGCAGCAAACACTGCGAATTCCGCCACaacagcggcagcagcagcagccgcgGTAGCCGCAGCTGTCGAAGCAGGAACGCTCTCATTGCCTAAGGAGAAGtgcaacaaatgcaaatcaatTCATGAAATTGGCTTACCATGTCCACCACCTAGCGCTGCGGCGCTCCAGCATCAGCATTTGATTGCCAGTAGTGAACGAGCTACgaacaatcatcatcagcaacagcagcagcatcagcagacTCAACACAGTAATGTCAATAAGTGTCCAGTGTGCGGTGTGGTTAGCCAGACGGCAGCCCAGGCACGCAAGCACATGGAGACACATGGCACTGTCAAAGCATTCCGTTGTACTATTTGCCTATACAAGGGTAACACTTTGCGAGGCATGCGTACCCACATTCGAACGcattttgataagaaaacGAGCGATGTTAATGAAGAACACTACATGACATGCATTTTCGAGGAGGATAACAACATGGAACTGGCATCAGCGGCACTGTCTTTGCAACAACAGGAACAGgctcaacaacagcaacagcagcagcaacaacaagcacAGGCACAGGAACAACAACTTCAAGCCCAACAGCAATTATACAACTGTGACATCTGTAACTATGCCTCAACCTACAAGGGCAATGTGCTTCGTCATATGAAACTCATGCATCCACAAATTGCCCTAAACTCTCCATCAATTTCCCCCGAGGCTGGCACTGGCGACTATGAGTCCAATGATATAACCTCCTCAATTAATGGCGAGACTAATACTAACAGCTTCACTATCAAGTCGGAGCCCCTGGAACACATGCCAACCAATCAAATCTCGAATCTTAGCCACATACACGACAATAACAACTCACCACCGACACCCACAGCCACAACGCCACATGTTCCACCAGAGCTAGTGATGCCCCACATCAAATCTGAACCAATGGATATAGCAATCGACAACACGACAACATCAGCCTTGCCACCGCCTGCTTTAACACCCACAGCCATGACCTCGCCGTTGGGAGCAGCAGTTGGTGCTGCAATGACAGTGGCAGCATCTGATGCCCTCAAGAAATACTGTTCCAACTGTGACATTTCCTTTAATTTCGTGAAAACCTACTTGGCGCACAAGCAATTCTACTGCAAAAGTAAACTGCTGCGTCCCGAAGTGCATGAGAGCCCAAGCCCGAATGCAGCCACGACGACTCCGATGCCCATACAATCACCCAATGAGTTGTTACTGATGCAAAAAAACAAGGAGAACATGCAACAGGAAGCGGCCATTTGA
Protein Sequence: MVSAEIQGKWWDKDRREGSKESVDYSELAEQNEDSKDLSAHELSEEKLELDPETTSSSNANQTETDNANEMSEQHEESEDHHHHHSEASLSSPRSSISHERTDHDKSDGDEQATEPDKGLDDCKTTSMSPMMKISQECIKIEEPAEIDIHLEQLERYISPPPPAMLRLASSTTSTTPSPVATPSPAHSDAADVERASTTPPTSTPIMPKLRLNALLASDPALKPDAKDLKKLHEEAQAHTSALPPPPALTKQEPLSNDGSPHLLKQSKTATEVSQTPRMKVFMCVPCGIGFSSPSTLEAHQAYYCSHRNKDVDDEHSGANQDKTGTASTAGASPSGVGTNNVQSSNSEPPAKVPRLGKQYACTQCSYSADKKVSLNRHMRMHQTSPATPASSLVTAANGGGTSASVGSNYEDSTSQQIDRYCSDCDIRFNNVKTYRAHKQHYCSSRRNDGQLTPKLETGTSGGISVPTTSTVKSTPLGHASGHSPQARNNKTPTPAMVAAAAAAAAAAAASLQPPPQPYFALPTSPIIIVPYSLIRAASLIPGPLTTSTAGIVNPDTTCFTLDNGALKPLATALNINALSNANPQVPLPHNSASNQIANVPSAESVTMLTEKNVSGRHMETNDAIPTKRKESGTRESAPLDLSLRRSPIVAMLQRQRLEMDTLLEAGKENLSLDESGSVTPEQIVCAPSLPSSPSMSPSPKRRTISPRSSGAGSTSSMSPPANVTVANFAATAGLLDNLPLRSMLPADLALKLSETNIMNPLLAKQNLELALKLSAAAAAAANSASPALAAAAAAGTASPAELAAAAVVAAGKLGLGVAPNTAVASAASSSQQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEGSIEGGTTSGGGGSTGSGDIKVSITPPMSGGAVGNAAAAVESTPPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGGAAAAAANTANSATTAAAAAAAVAAAVEAGTLSLPKEKCNKCKSIHEIGLPCPPPSAAALQHQHLIASSERATNNHHQQQQQHQQTQHSNVNKCPVCGVVSQTAAQARKHMETHGTVKAFRCTICLYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDNNMELASAALSLQQQEQAQQQQQQQQQQAQAQEQQLQAQQQLYNCDICNYASTYKGNVLRHMKLMHPQIALNSPSISPEAGTGDYESNDITSSINGETNTNSFTIKSEPLEHMPTNQISNLSHIHDNNNSPPTPTATTPHVPPELVMPHIKSEPMDIAIDNTTTSALPPPALTPTAMTSPLGAAVGAAMTVAASDALKKYCSNCDISFNFVKTYLAHKQFYCKSKLLRPEVHESPSPNAATTTPMPIQSPNELLLMQKNKENMQQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00063106;
90% Identity: iTF_00063106;
80% Identity: -