Basic Information

Gene Symbol
ham
Assembly
GCA_037043315.1
Location
JBAMAV010000449.1:112644-141172[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0057 0.68 11.4 0.0 2 23 196 218 195 218 0.91
2 9 0.49 59 5.3 4.5 1 23 225 248 225 248 0.88
3 9 8.9e-07 0.00011 23.3 3.0 1 23 254 277 254 277 0.97
4 9 1.3e-06 0.00016 22.8 1.9 1 23 283 305 283 305 0.96
5 9 4.1e-05 0.0049 18.1 5.0 1 23 311 333 311 333 0.99
6 9 0.0022 0.26 12.7 1.7 2 21 341 360 340 361 0.95
7 9 1.4e-07 1.6e-05 25.9 1.4 1 23 896 918 896 918 0.96
8 9 3.4e-07 4.1e-05 24.6 0.9 1 23 924 947 924 947 0.97
9 9 5.9e-05 0.007 17.6 6.6 1 23 953 975 953 975 0.98

Sequence Information

Coding Sequence
ATGGAACATTTCTTTAATGATCAAGCACAAGCGGAACGCATACTTATGGAGATGGCACGTCTACGTGAACCTGTCTGTGATCTGGATATACGTGATAATGGTGTCTATGCAAAGACAAAATTGCGTCGGGGCACACGTTATGGTCCATTTCCGGTGAAATTGTGTCAGGAGCCCACCGAACGAAGTCTCGCTTGGGAGGTAACTGTTGATCCACATTTTCATGGCTGGCTAGAACCCAGTGCCGATGTCTCAAAGTGGCTTAAAAAGATACGCGCTGTTAATGTTGATAAAGAAGAGGCTAATCTTAGGAATTTTATTATTGGGGGTTATCTTTGGTATGAGACAAATCGTGATATTAATGCGGGCGATGAGATCACAATCGATGGTGCACCCAAACCGCCTTATGAATTAAATGAGCATTTTCTTAGTGCAGCATCATTGCCAAGTGATGATCGCAGTGATCGGGATAATGGCTCCCATTACAGTGGTGACGAATATCCAAAAGAAAAACCCATTCATTTGCgccaacaccatcaacaacatccTACCAATACTGTTTTCATTGATGAAGACGCTTACGATATACGCTGTGAAATTTGTGATAAGGAATATGCTGATTTAGATAGTTTAGATGATCATCTTGTCAATGATCATCATTTCCCAGCCGACGCTTTTGCCTGTGAGACTTGTCATCAACGATTTTGTCATCGACCCTTGGTCTTAAAGCATCGTGGATTAGTTCATAACGATATTAAGAAATATCCTTGTGAAAATTGCTCTAAGTCATTCTGTGACACCTCGAATCTACAGCGTCATATTCGTAATACGCACGTTGGTGCTCGAAGTCACGCGTGTCCGGAATGCGGTAAAACGTTTATGAGCTCATCGGGACTCAAACAGCATATGCATATACATTCCTCGGTAAAGCCATTCCAGTGTGAGGTCTGCTTTAAAGCGTATACGCAATTCTCGAATCTGTGTCGGCATAAGCGTATGCATGCCGGTTGTCGTCTTCAGATCAAGTGTACCAAATGCAGTCAAAGTTTTAATACAGTCACATCGTTGACAAAGCATAAGCGTTTCTGTGACACCGCCGGTGTTGTagatcatcatcaccagcaacagcagcatcattcTCGTAGTGCTCACTCTCATTAttataacaacagcaatcacCAAAACAGCAATcataccaataataataataacagcgCCCTGGATCAACATCTACTTCATCATTCACAGCAGCAGCCgcaacaccagcagcagcaagtgtCCCCAGTTGGATGTGGTGTTGGTAATATGACGACGCCTCCGCATCCTTTATTCATGTTCCGTACAGCGCCACCATTTTTCCCCGGTTTTCCGGCACCCGGCGCTTATGgtttgcaaaatgtttttcCGCCGAGTCCATTGCAAGCCGCCAACTTTCCAATGTTCTTTCAAAAATCCAATCTGGACATTAGAATACCACAACTTAATCAGAATTTGAGTTCACCGAATTCACCGTTCCGGCCACAACTAAATTACGGTTTAGCGGCggctgctgcagcagcagcggcaacGGATAACAAAAAACCCAAGTTGGAAATGGAAgattttgatataaaatcCATGTCAACGCTTCTCAAATATGAAAACATGAAAAGGGAAGGTGAAGAGCAtgacaagcaacaacaaaaacgtcGGGCTGGCAACCAAGGTTCCGATGATGAATCCAAACATTCAGTAAAAACGGAAGCGTTCCtgaaaagagaaaatgatGTGGAAGATATGGaaaatgatggtgatgacgatgaagatcACGATAAATTATCACATAAGAGTGACGACCATCAAACTGAAGATGATCGGaaatcCATTGACATTGTAAGTACACCTCCAGCTTCCGGAAGCAATGAATCAAATGGTGCTGCTAAACAAACAGAATTGCCACTGGACTTGAGTGTCACTCGCAAACGCAAGATTTCTATGAGTAGCAACAGTGGTTACAACAGTCTAGGCGCCTTCCTAAAGGAATTCCAAAGAGGCGCAGCCGAGTCTCCTGCGACTGCAGCAGAAGAGTGTGTTCCCGACAAACAATACAATGATCGGAAAATATCTGAAAAAAACTCAACAGATGAAGCTGATTCCTCGGCATCACATCAATCCTTTAAGGGCAGTAGCAGTCCCACTCGTTCAGCTTCAACGCCTGGTCCAACTCCCTCACCATCACCACCGACCAGTGCCGGCGAATTAAGCTCGCTATCAGAAGGTGCTGCAGCAGCGGCTGCAGCTGCAACCTCAGCTATGATCTGTCCACGACCAATTCATCCATATTTACTTGAGGAACTTTATCGTACACATTCACTAGGTGCTGCAGCAGGTTTCCCATCTCGTCCGTTTCCTTTTTTAGGCCCAATGGGCGGACGGCCGACTTTTGAACAAGCAGCTGTGGTGGCAGCAGCCTCAGCGGCAGCGGCAGCAGTTAATGGTAATCAGCCAACTACACCAACTCATAATTCAGCAACGCcgcatcaccatcatcataatcataatcataatcaccATCAGCGCCACCATCAACGAAGTTTGCCGTTTCCGCCCGAATCAAATTTCCGTGATGCCTTGCGAGCCGTCGGTCTCTCGAGTAGCGTGCTAGCAGCTGCTGCCGCCGGTAATACTCCACACAAAGTCAAAGATCGTTACTTGTGCAAATTCTGTGGTAAAAACTTTCCGCGCTCAGCAAATCTAACACGTCATCTGCGAACCCACACCGGCGAACAACCGTACACATGCAAATATTGCGATCGTGCCTTCAGTATCTCATCGAATCTGCAGCGTCATGTGCGAAACATACACAATAAAGAGCGGCCGTTCCGTTGTCATTTGTGTGATCGTTGTTTCGGTCAACAGACTAATCTCGACCGTCATCTCAAGAAACATGAGGCCGATACAACAGGCACTTTTGGGTTTGGTGATTCACCTTCATCTAATGAAGCCGAACGTGAAGATTCTTATTTCGATGACATCAGATCATTTATGAATCGCGTCTATACACCATCAAGCATTGGTGGTGCTGATAATGACATCGATGAGTTTGCGGGCAGTGATATCGAAAATGAATTAACCAAATTATCGACAACAAATCAATCATTATCAAGTGAAACAACACCGATCACACCAACGACACctacaaatgcaacaaatgaaacagcaacagaagcagttgaagaagGAGAACGAGAAACAGAAGCAGAAGTAGCAGAAGATTTACTCAAGGATGAAGttataagcaacaacaacaataacaactctGGTGAACCGATTGCGGTAGATGCCTAA
Protein Sequence
MEHFFNDQAQAERILMEMARLREPVCDLDIRDNGVYAKTKLRRGTRYGPFPVKLCQEPTERSLAWEVTVDPHFHGWLEPSADVSKWLKKIRAVNVDKEEANLRNFIIGGYLWYETNRDINAGDEITIDGAPKPPYELNEHFLSAASLPSDDRSDRDNGSHYSGDEYPKEKPIHLRQHHQQHPTNTVFIDEDAYDIRCEICDKEYADLDSLDDHLVNDHHFPADAFACETCHQRFCHRPLVLKHRGLVHNDIKKYPCENCSKSFCDTSNLQRHIRNTHVGARSHACPECGKTFMSSSGLKQHMHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHAGCRLQIKCTKCSQSFNTVTSLTKHKRFCDTAGVVDHHHQQQQHHSRSAHSHYYNNSNHQNSNHTNNNNNSALDQHLLHHSQQQPQHQQQQVSPVGCGVGNMTTPPHPLFMFRTAPPFFPGFPAPGAYGLQNVFPPSPLQAANFPMFFQKSNLDIRIPQLNQNLSSPNSPFRPQLNYGLAAAAAAAAATDNKKPKLEMEDFDIKSMSTLLKYENMKREGEEHDKQQQKRRAGNQGSDDESKHSVKTEAFLKRENDVEDMENDGDDDEDHDKLSHKSDDHQTEDDRKSIDIVSTPPASGSNESNGAAKQTELPLDLSVTRKRKISMSSNSGYNSLGAFLKEFQRGAAESPATAAEECVPDKQYNDRKISEKNSTDEADSSASHQSFKGSSSPTRSASTPGPTPSPSPPTSAGELSSLSEGAAAAAAAATSAMICPRPIHPYLLEELYRTHSLGAAAGFPSRPFPFLGPMGGRPTFEQAAVVAAASAAAAAVNGNQPTTPTHNSATPHHHHHNHNHNHHQRHHQRSLPFPPESNFRDALRAVGLSSSVLAAAAAGNTPHKVKDRYLCKFCGKNFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHLCDRCFGQQTNLDRHLKKHEADTTGTFGFGDSPSSNEAEREDSYFDDIRSFMNRVYTPSSIGGADNDIDEFAGSDIENELTKLSTTNQSLSSETTPITPTTPTNATNETATEAVEEGERETEAEVAEDLLKDEVISNNNNNNSGEPIAVDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00063032;
90% Identity
iTF_00063032;
80% Identity
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