Basic Information

Insect: Amiota communis
Gene Symbol: ZEB1_1
Assembly: GCA_037043315.1
Location: JBAMAV010001149.1:1318674-1322490[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 2 2.3e+02 3.4 0.5 3 23 347 368 345 368 0.92

2 9 6.9e-05 0.0082 17.4 0.5 1 23 372 396 372 396 0.92

3 9 0.57 68 5.1 1.6 1 23 413 436 413 436 0.94

4 9 0.00013 0.015 16.5 1.1 1 23 443 465 443 465 0.98

5 9 1.6e-06 0.00019 22.5 3.6 3 23 475 495 475 495 0.99

6 9 2.1e-06 0.00025 22.1 4.4 1 23 501 523 501 523 0.99

7 9 3.6e-05 0.0043 18.3 1.2 1 19 529 547 529 550 0.95

8 9 4.1e-06 0.00049 21.2 0.7 2 23 671 692 670 692 0.98

9 9 4.3e-05 0.0051 18.0 1.3 1 23 699 721 699 721 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	2	2.3e+02	3.4	0.5	3	23	347	368	345	368	0.92
2	9	6.9e-05	0.0082	17.4	0.5	1	23	372	396	372	396	0.92
3	9	0.57	68	5.1	1.6	1	23	413	436	413	436	0.94
4	9	0.00013	0.015	16.5	1.1	1	23	443	465	443	465	0.98
5	9	1.6e-06	0.00019	22.5	3.6	3	23	475	495	475	495	0.99
6	9	2.1e-06	0.00025	22.1	4.4	1	23	501	523	501	523	0.99
7	9	3.6e-05	0.0043	18.3	1.2	1	19	529	547	529	550	0.95
8	9	4.1e-06	0.00049	21.2	0.7	2	23	671	692	670	692	0.98
9	9	4.3e-05	0.0051	18.0	1.3	1	23	699	721	699	721	0.97

Sequence Information

Coding Sequence: atgtcTGCAATATGTAAATTGTGTACGGCTCAATTAGTTGACGATGATATCGAACAAATTGCTGGCCATGAAAATCGTGTGGAATTGTTAGAATGCATTTTTGCACAATTGAATTTGCagTATGACGCTAAGGATATTTTATGTGTTACTTGTCAAAAAAACCTAAAAGCTGTtaaattggtcatgagtcgCTGGCAGGAGGCCCAAAGGAAACAACGCGCGACTACAATTTCTTCAGTCAAGACGGCAACGAGTACGAGTACGCCAGTAGCAACTATTAAACAAGTGACTCTACTTAAAAAACCAGCAACGGCATCATCTTCACCACCATCACCTAAAGATCAAgtgcaaacaaataaaaaatctatagaaaatgaaaaaatacaaaataatcaaaaaacgAAGATGGCGATTCAAAAGAAAGTAGGCAATACATCAGCTGCCAAATTGCGTTTGGCTGCAAGTTCAACCAAAGTAAAATCTAAAATAGTCAAACCAACTGTGAAAACAGAAGAATGTGAAGAAGAAATATCAGAATTAATTGACTCCGTCGATGAGAAAGAGATCATTCAAAAAAGAATTCCGCTAACACGTAGCGTATTAAAAAAGCAACAGAAAACAATTGTTGAAAcggtaacaaaaacaattaaacaaaagccCATTCGAAAAATTCATAACATTGGATACAGTAATGAGGAAAAAGaagtagtagaagaagaagaagaagaatctgAAGATGAAGTACAGCCACAAATACAGattgaacacaaaaaaacaaaaaagtctaaaaacaagaacaagaacaatgaTTCTGCAGAGGAtttggaagaagaagaagaatataaagaGGTAGTCAATGAGAATGAAATTGATAGTGACGCTGAATTTCAAACAATTGAACCTGTCGATATAAACGATATTGGTAGTATGGTACAAATTGGTTTGGTACGCAGTGCTAATGGTGATACTATAGCacaaatatttgaagaaaataagGCCGGCGGTAAGGAGTTTGAATCACTACAATCATGTTTAATATGTGTACTCTGTCACGATGTTACAACGAGCATACGTGATTTTCAAAAGCATCTTAAGGCTGTACATAAGTATACTTACGAATGCAAAGATTGTCTTCAAACATACGACACACTGGACAATTTGGAAAAGCATCAGAAGTCCGACGATCATTGTGGTGTCAACACTATAAGTAGTGAAGAGGAACGAAAAATGATATTCTTCGAATGTGCTAGCTgcgaaaaagtttttcttgaaTTCTACAATATGAGTCGGCATCATCGTGATGTCCATCGAGCTCCATGCGATCGCTACAAATGCACACAATGTGGCGCTTATTTCAAGTACAAAATCAGCCTGACCGAGCATCTTGCTAAACATATGCAGATCAATACCAACTCAGTAGGTTGTCCCCACTGTTATCGTatgtttaaaaacaattatcaACTAAATCGACATATGCGTATACACACTGGTGAAAAGCCCTATGAATGCGAAACGTGTAAGAAAAAATTCCGGCACAGTGCAAATTTGACTGTACACAAACGAACTCATACTGGTGAATTACCATTTAAGTGTACCATTTGTGACAAAGGATTTGCCACTTCAACGCATATGCGTCGTCATTTCGTAACTTGTGAGAAACGTTTAAAACGATCGAACAAACAATCGACAACAATGGTTTCAttgaaagaagaagaggaatTGCGCTATGAACCACAAAAATCAACACAATCTGAAGTTGTTTTCACTTTGAACACtgaacaaataattaatagCAATCAAAATGATTCATTGCTAAAACGTAGTTTGGttaaaaaagaaggaaaaggaGCCACTAAACGAAGGGCTGTTGAAATGGCCACCACACCAAatacaaagaaacaacaaacgCAGCAAGTACAGaagaagcaaaaacaacaagatgaaaaaattcaaattgtagaAGTGGAAATTTTACCAAATGTTGGAAAGAAACAATCgccaattttaatgaaatgtgaATTATGTTCCAAAATCTTTAAAGAACAAGATGATTTGAGGAAGCATATGGCTACACATGAGAAGTCAGCTGTAACATATCGTTGTACCCAATGTCCAATAAGATTTTCAGACCCATATCTCTTTAAACGTCATAAATTGGAACATAGTTGTATGaaaccatcaacatcatcgtcatcggcATTGGCATTAAAAAAACCAGTAAAACCAACAAGGACTACgacatatgatgatgataaatatgctgatgatgatgaaagtgaAAACAATCAAGAATtagatgatgttgatgatgatgatacaattTTACTTGATTTCCAAATCGATAAATTGGAACCTGTTTCACCAACTATTCAACTTCGGTCGCAAGATGATGGTGTCGATACAAGTACCCTAAATAATTTTCGTATTGTAACCATAGATGATATGTAG
Protein Sequence: MSAICKLCTAQLVDDDIEQIAGHENRVELLECIFAQLNLQYDAKDILCVTCQKNLKAVKLVMSRWQEAQRKQRATTISSVKTATSTSTPVATIKQVTLLKKPATASSSPPSPKDQVQTNKKSIENEKIQNNQKTKMAIQKKVGNTSAAKLRLAASSTKVKSKIVKPTVKTEECEEEISELIDSVDEKEIIQKRIPLTRSVLKKQQKTIVETVTKTIKQKPIRKIHNIGYSNEEKEVVEEEEEESEDEVQPQIQIEHKKTKKSKNKNKNNDSAEDLEEEEEYKEVVNENEIDSDAEFQTIEPVDINDIGSMVQIGLVRSANGDTIAQIFEENKAGGKEFESLQSCLICVLCHDVTTSIRDFQKHLKAVHKYTYECKDCLQTYDTLDNLEKHQKSDDHCGVNTISSEEERKMIFFECASCEKVFLEFYNMSRHHRDVHRAPCDRYKCTQCGAYFKYKISLTEHLAKHMQINTNSVGCPHCYRMFKNNYQLNRHMRIHTGEKPYECETCKKKFRHSANLTVHKRTHTGELPFKCTICDKGFATSTHMRRHFVTCEKRLKRSNKQSTTMVSLKEEEELRYEPQKSTQSEVVFTLNTEQIINSNQNDSLLKRSLVKKEGKGATKRRAVEMATTPNTKKQQTQQVQKKQKQQDEKIQIVEVEILPNVGKKQSPILMKCELCSKIFKEQDDLRKHMATHEKSAVTYRCTQCPIRFSDPYLFKRHKLEHSCMKPSTSSSSALALKKPVKPTRTTTYDDDKYADDDESENNQELDDVDDDDTILLDFQIDKLEPVSPTIQLRSQDDGVDTSTLNNFRIVTIDDM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -