Basic Information

Gene Symbol
-
Assembly
GCA_963575735.1
Location
OY754491.1:3013276-3016378[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1.1 1e+02 4.0 0.0 2 15 378 391 377 397 0.81
2 17 5.5 5e+02 1.9 0.0 2 20 418 436 417 438 0.90
3 17 0.00043 0.039 14.8 0.2 1 23 446 468 446 468 0.97
4 17 0.0095 0.86 10.6 0.3 2 23 480 502 480 502 0.92
5 17 0.00014 0.012 16.4 0.1 1 23 508 530 508 530 0.98
6 17 4.1e-06 0.00037 21.2 3.4 1 23 536 558 536 558 0.96
7 17 0.00065 0.059 14.2 2.2 1 23 567 589 567 589 0.96
8 17 5e-06 0.00046 20.9 1.1 1 23 595 617 595 617 0.98
9 17 2.5e-07 2.3e-05 24.9 0.2 1 23 622 644 622 644 0.98
10 17 0.0064 0.59 11.1 4.0 1 23 651 673 651 673 0.98
11 17 0.00026 0.024 15.5 0.2 2 23 693 714 692 714 0.97
12 17 0.00027 0.024 15.4 0.7 2 23 722 744 721 744 0.95
13 17 0.1 9.5 7.3 0.4 1 23 750 772 750 772 0.97
14 17 0.00014 0.013 16.3 3.1 1 23 778 800 778 800 0.98
15 17 1.9e-06 0.00017 22.2 2.4 1 23 806 828 806 828 0.97
16 17 1.3e-05 0.0012 19.6 2.1 1 23 834 856 834 856 0.98
17 17 4.9e-06 0.00045 20.9 0.1 2 23 862 883 861 883 0.96

Sequence Information

Coding Sequence
atgaaaattgtatgcTCGGCAGCGTCATGCAAGTACTCGTCGGAGGGCGAAGATTCgtcgaatattattttcataagctttccgaataacgACACTGCTTCGGCATGGGCGCAAAATTGCGGTCGACCGGATTTGCTGATGAAACCGGCGCAGGATCTGCACACCAGTCAGTACATATGTTCGGATCACATAGAGGATCGATTCTTCATAAGCAAAACAAATCCGATTGTCATAGCGCAGGGAGCTGTGCCTACTCTGTTCGGAGTGACGACTCGTTCAACTAACATCATGGATTCCATGAAGGCGAACTGTCGGTCGGAACGCGAGATAAACTCACTGCAATTGACAGAATGTATAAATGTCGTCGATCGTGTCTGCCACGAGCAAACTCTAACCGAGGTCCAGTCTGCCTACCGAGAAGAAGAGGAGACGAATAGCACGAACAGTCTTAATTTTTGCAGCATAAATGTAAACATGGATCAGCTTCAAGGGACGTCGGTCAGATTGACCAGTCTGTGCCGAATTTGCGGCCATGCGACCGCGGATGGAACAGAAATATTTGGAGCCAAAGGTTCGGAgttgaaattgaaagaaaaaattgaattacacACGCCCATAAGCGTGCATCCCGACGAGTCGATGCCACGAAAGATCTGCTCAAACTGTTGCGAGAAACTGGAAGTCGCTCACTCCCTTGTAGTCACTTGCTTGCAGGCGGACATGAGATTGAggagattttttaataacagcAGCAAATCCGGCTATGATCCGAAATTCGAGAAGCTGGTGACAATGTGCGCACGGGAAATTGCCGACGAAATTACCTTGAACAATGTCGTCGATGGCAAAGATCCGTCGAGCGACGCGAAGAAGATCGAAAAGACAAGCTCCGCGAACAGATTCAATTGCAGATGGAAGGACTCCTCGGGCAACATCGAATTGGAGCAAGTGCAAATATGTCCGATCACCGAAACGAGCaacgaaaatatttcgagCTTCAAGTACGTTGTTCATTCGGATTTGAACAATTTGCTTCAAGCGCTGAGCGGTATCAGTCCCAAGAATGACGAGAGGAGCAACGAATTGTCCGAGACGATCGTTGAGACTGTGGAGACCGAAGAAAGATCACTGGTCTGTCCGAACTGTAACGTTATGTTCGAGACGCGGGATATCTACGAGAGCCACGCAACGCTCTGCAATGCCGAAGAAGAGGCCGGTCTGAAAGAAACCATGGAACTGGAATCGAATATCGTTTGCCCCGTGTGCAGGCTCGATTTGGGCAGTGCCGAGTACTTCGAGAAACACAAGATTTCGTGCGGCGAGGCAACGGCGCAATTCAATTGCCAGCAATGCGACGAATTATTCACCGACAGGGACGAACTCGAGCTTCACGCGATGTCGCACAATGAGAGAAGTCATTCCAGCGTATCGGATCGACGATGCGGCTACTGTCTCGCGGTGTTCGAAACGCGGAAAGAGCTGCAGAGTCACATTACCGATACTCACGACGGTCAGCCGCTCTACAGGTGCAGCGTCTGTGAGAAAACGTACGAGAAGTGGGCGAACCTCGACGTTCACGAGGCGACTCATCGGTCGGATAAGCCTTATCTGTGCGATCTTTGCGGCAAGAGTTTTAAACATTCCAACAATTTGAGAGGCCACAAGAGAACCCACCTGGACGAAGCGACGAAGAAACGTCACGTTTGTGAAGTGTGTGGTAGCGCGTTTAGATCGAGATTTCACCTTCGGGAACATGCGAATCAGCACAATGGGAACAAGCCGTACACGTGCGAGGAGTGCGGAAAAGCGTTTTACAAGAGAATACAGTTGCGACAGCATAGACTGTCTCACGGAACGAAGAAGTATGCGTGTCCGATTTGCGGAGTGACGTTCAATCGGCGAGGTAACATGAATGCGCACATGAAGAGGCACGACAAGAGCGACGGAATGTATACGTGCAGCGTATGCGAGTACAAATGCAATTCCATGAGCGAACTGAAGATGCACCGAAAGCAACACTCCGAAAGCGACATAATGGAGAGTATAAAGCTCAAGACAGCCGACAGGACTGTGTGGCAGTGCAAGATATGCGACAAGGTATTTCCGAAACGGGCCATTCTCCTGAATCACGAACGCACCCACACCGGCGATCAGACGAAAGTCGAGTGCGACAAGTGCGGCAAGAAATTGGCGAACAAGAGTTCACTGAGGTATCACAACAAGTCCATACACTCGACCGAACGGCCGCACACGTGCCAATTCTGCGGGGACGCCTTCGTCTCGAAGGAAGCGAGATTGATACATGAAAGAATTCACACCGGCGAACGGCCTTACATGTGTAAAATTTGCGGTATGCGGTACAGATGCTCGAGTAATCTCAGTCAACATATGAAGATTCATTCGGCTCTGAGACCGCACGTTTGCCAATACTGCAACAAGACTTTCAGTCGGAGAGGTACTCTGAACGTTCACGAGAGAATTCACACGGGACTCAAACCGTTCGTCTGCGATATTTGCCGTCGATCGTTCTCGCAGAAGAACGATATGTTGAAGCACACGAAGACTCATAGAGCGAAGTCAATTCGGTGCGAGAAATGCGACGAGGTTTTTGCGACGAAAAGTGAATTGTTGAAACACTTGGACGTTCACGAGCACAGTGTTGTCGAGGATTCCGCCATACAGTCGTACGACGAGATAGTCGAACCACTCGAATCGTACACGCTGGGCATACAGTGTCCGGCTATGCAGTAA
Protein Sequence
MKIVCSAASCKYSSEGEDSSNIIFISFPNNDTASAWAQNCGRPDLLMKPAQDLHTSQYICSDHIEDRFFISKTNPIVIAQGAVPTLFGVTTRSTNIMDSMKANCRSEREINSLQLTECINVVDRVCHEQTLTEVQSAYREEEETNSTNSLNFCSINVNMDQLQGTSVRLTSLCRICGHATADGTEIFGAKGSELKLKEKIELHTPISVHPDESMPRKICSNCCEKLEVAHSLVVTCLQADMRLRRFFNNSSKSGYDPKFEKLVTMCAREIADEITLNNVVDGKDPSSDAKKIEKTSSANRFNCRWKDSSGNIELEQVQICPITETSNENISSFKYVVHSDLNNLLQALSGISPKNDERSNELSETIVETVETEERSLVCPNCNVMFETRDIYESHATLCNAEEEAGLKETMELESNIVCPVCRLDLGSAEYFEKHKISCGEATAQFNCQQCDELFTDRDELELHAMSHNERSHSSVSDRRCGYCLAVFETRKELQSHITDTHDGQPLYRCSVCEKTYEKWANLDVHEATHRSDKPYLCDLCGKSFKHSNNLRGHKRTHLDEATKKRHVCEVCGSAFRSRFHLREHANQHNGNKPYTCEECGKAFYKRIQLRQHRLSHGTKKYACPICGVTFNRRGNMNAHMKRHDKSDGMYTCSVCEYKCNSMSELKMHRKQHSESDIMESIKLKTADRTVWQCKICDKVFPKRAILLNHERTHTGDQTKVECDKCGKKLANKSSLRYHNKSIHSTERPHTCQFCGDAFVSKEARLIHERIHTGERPYMCKICGMRYRCSSNLSQHMKIHSALRPHVCQYCNKTFSRRGTLNVHERIHTGLKPFVCDICRRSFSQKNDMLKHTKTHRAKSIRCEKCDEVFATKSELLKHLDVHEHSVVEDSAIQSYDEIVEPLESYTLGIQCPAMQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00058882;
90% Identity
iTF_00058882;
80% Identity
iTF_00058001;