Basic Information

Insect: Altica viridicyanea
Gene Symbol: topi
Assembly: None
Location: GWHAMMQ00000720:226014-230213[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0046 0.14 12.6 2.1 2 21 101 120 100 121 0.94

2 13 7.7e-06 0.00024 21.4 1.5 1 23 145 167 145 167 0.98

3 13 0.024 0.75 10.4 2.0 3 23 175 195 174 195 0.95

4 13 0.072 2.3 8.9 0.3 2 19 214 231 213 234 0.83

5 13 0.00089 0.028 14.9 1.1 2 23 295 316 294 316 0.97

6 13 0.003 0.093 13.2 2.8 2 22 359 379 358 382 0.88

7 13 0.00018 0.0058 17.0 0.2 1 23 492 515 492 515 0.97

8 13 0.0055 0.17 12.4 0.2 1 23 519 541 519 541 0.97

9 13 1.5e-06 4.6e-05 23.6 2.4 1 23 547 569 547 569 0.98

10 13 0.042 1.3 9.6 0.1 1 23 575 600 575 600 0.96

11 13 0.14 4.5 7.9 2.9 1 23 606 628 606 628 0.86

12 13 9.1e-06 0.00029 21.1 0.3 1 23 634 656 634 656 0.98

13 13 6e-06 0.00019 21.7 2.2 1 23 662 685 662 685 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0046	0.14	12.6	2.1	2	21	101	120	100	121	0.94
2	13	7.7e-06	0.00024	21.4	1.5	1	23	145	167	145	167	0.98
3	13	0.024	0.75	10.4	2.0	3	23	175	195	174	195	0.95
4	13	0.072	2.3	8.9	0.3	2	19	214	231	213	234	0.83
5	13	0.00089	0.028	14.9	1.1	2	23	295	316	294	316	0.97
6	13	0.003	0.093	13.2	2.8	2	22	359	379	358	382	0.88
7	13	0.00018	0.0058	17.0	0.2	1	23	492	515	492	515	0.97
8	13	0.0055	0.17	12.4	0.2	1	23	519	541	519	541	0.97
9	13	1.5e-06	4.6e-05	23.6	2.4	1	23	547	569	547	569	0.98
10	13	0.042	1.3	9.6	0.1	1	23	575	600	575	600	0.96
11	13	0.14	4.5	7.9	2.9	1	23	606	628	606	628	0.86
12	13	9.1e-06	0.00029	21.1	0.3	1	23	634	656	634	656	0.98
13	13	6e-06	0.00019	21.7	2.2	1	23	662	685	662	685	0.98

Sequence Information

Coding Sequence: ATGAACTGCCTTGATAGTATTATTACAAATGTTTACAAAGTGGAAGATAATGGATCTGTTGTATCAGCATTGAGATATGAAATGAACTCTAACACCAAGGACCCCATCTCAAAGACATTCTTTTGCCCTAAAAACGTAAGTTTTGATCCTAAAGATTTGTTATCCGATAACCAAATGATAAAACTCAACTACATCCACTTCGAAATTCTAGATGAAGTTAATATTAAATGTTTTCGTTTCGAGGAGAGTGACGATGTATCTATAACTAGTAAACAAGTATTAAATATTCCTACAATGATTCGTTGCCAAAATTGTGAAACAAACTTCCCAACGAAGTACCAATACCAACGACATCAATGTGAATTTAATGCTGAAAAAGTGGTATTAAAATCAGATGTTAGTTGTAAAGAAGTGGATGGAATTCGTGTTAAATATGTTTGTCAATTTTGCAATAAACAATTTGTTAATACTAGTAATTTAGCTCGACACCAATCGAGCCATGAAAATACTCAAGAAAATATTTGTGAGCATTGCAATAAACAGTTTATTAGTGAGAATAGATTAAGGATACATAAAGAGAATCATTGTAAAAAAGCTGGTGATATATCGAAATTTTATAGAAGTGATGTTACTGTATGGAAATGTAAAAAGTGCCACGAAGTATTTTCATCACCGTTAACTGCTAATTATCACGTATCAATATGTAGAGAAGTTATTGAAATAGATGATCAACTTACGACTAATAATACTAACAAAGAAAATAATTTGGTGTTAGATTTAACATTAGATGATGGTGAGAAAAGTATTTTAAATGATATTAACAATAAAGATACTTCACTTGATGATAAAAACATAGAAAAAATGCTTACAGAACTCCTATTGCAATGTGAATTTTGTAATAGAACTTATGCTGAAAAGAATTTATTGTTAATGCATCAAAGAAAGCATACAACAGCTAGAAATTACGAATGTATAAATTGTTTTAAAGTATTTGATTCATATGTATTAGCTTCGCAGCATTGGATGAAAAAATGTTCAGAATATGTTAGCTTATTTTATTTACCGAAATTAATTTATTGCGAGTATTGCGATCGAACATTTAAATCCCATGAATTATTATATACTCACAAAATTAAAAAGAAACATTACACATCAAAACTTCACCTACCCAGTTGCACTTCCAACGAAACTCATTCAGGTAGTAATGATAATATGAACATTGAAAAAAATCTGGATAACAAAGAGATTTTGAATAAACTTATTGAGGATGTATTAAAAACTCTTGATGTTCCTGTAAATAAAATTAACAGCTACGATTCAGAACAAAATAAAGATAAAAGTAATGATCAAAATAAGGAAAATGAAGGTGGGGATGCCATCGAAAAAAAGAAAAGAGGAAGGAAACGTAAATGGCCTAAAAATCAATGCATTAAAACGAAGAAACTTTGTATGGAGGTTGATGAGGGGTTTAAATATCAATGCGAACGGTGTGTGAAGGTTTTTGCAAATGTTTCGGATCTCGAAACACACAGAGAGAAGGAACATGCTTCAAATTTTACTTGCGAGGAATGTGGTCAGGTTTTGCATAGTGCAAAAGCCTTAATGATTCACAGTCGTGCCCATAAAAGTCTGAAGCCCTACGTATGTGAAACTTGTGGACGTAGTTACTCGCAAACATCACATCTTTGGCAACATATGCGGTTTCATCAAGGCATTAAACCATTTGCTTGTCCTCATGAGGGTTGTGAAGCTCGATACACTATTAGACCCGATTTAAAAGATCACATCAGAAAAGCACATACTCGAGAAAGACCATTTAAATGTAATGTTTGTGATAAATGTTTTTTGACTGGTTCAGTATATTATCAGCATCGATTAATCCACACCAACGATAGAAGATATGCATGTGATCTTTGTCCAAAACGTTTCTTTAGAGCTGATGCTCTAAATAATCATAGAAGAATCCATACTGATGAACGTCCATATCCATGTCATGTGTGTGGAAGAGAATTCCGACAAAAAGGTGATAGAAATAAACATCTTAGGACACAACATCCAGATACTTTAGCCGTTTGA
Protein Sequence: MNCLDSIITNVYKVEDNGSVVSALRYEMNSNTKDPISKTFFCPKNVSFDPKDLLSDNQMIKLNYIHFEILDEVNIKCFRFEESDDVSITSKQVLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVVLKSDVSCKEVDGIRVKYVCQFCNKQFVNTSNLARHQSSHENTQENICEHCNKQFISENRLRIHKENHCKKAGDISKFYRSDVTVWKCKKCHEVFSSPLTANYHVSICREVIEIDDQLTTNNTNKENNLVLDLTLDDGEKSILNDINNKDTSLDDKNIEKMLTELLLQCEFCNRTYAEKNLLLMHQRKHTTARNYECINCFKVFDSYVLASQHWMKKCSEYVSLFYLPKLIYCEYCDRTFKSHELLYTHKIKKKHYTSKLHLPSCTSNETHSGSNDNMNIEKNLDNKEILNKLIEDVLKTLDVPVNKINSYDSEQNKDKSNDQNKENEGGDAIEKKKRGRKRKWPKNQCIKTKKLCMEVDEGFKYQCERCVKVFANVSDLETHREKEHASNFTCEECGQVLHSAKALMIHSRAHKSLKPYVCETCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKAHTRERPFKCNVCDKCFLTGSVYYQHRLIHTNDRRYACDLCPKRFFRADALNNHRRIHTDERPYPCHVCGREFRQKGDRNKHLRTQHPDTLAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00387486;
90% Identity: -
80% Identity: -