Basic Information

Gene Symbol
-
Assembly
GCA_946251895.1
Location
CAMIUG010001019.1:31962-37356[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 3.5 3.4e+02 3.0 0.3 1 23 132 154 132 154 0.89
2 17 5.4 5.3e+02 2.4 0.3 3 23 180 201 180 201 0.94
3 17 0.038 3.7 9.1 0.1 1 23 225 247 225 247 0.97
4 17 0.00032 0.031 15.7 0.2 1 23 251 273 251 273 0.98
5 17 0.00013 0.013 16.9 0.5 1 23 278 301 278 301 0.96
6 17 0.0032 0.31 12.5 0.3 2 23 308 330 308 330 0.93
7 17 0.11 11 7.7 0.8 1 16 337 352 337 354 0.89
8 17 0.022 2.2 9.9 1.5 1 23 415 437 415 437 0.96
9 17 0.015 1.5 10.4 0.2 2 23 465 487 464 487 0.95
10 17 0.00027 0.026 15.9 2.3 2 23 511 532 510 532 0.97
11 17 0.015 1.4 10.4 0.2 2 23 536 557 535 557 0.96
12 17 0.00042 0.041 15.3 1.3 1 23 562 585 562 585 0.95
13 17 5.7 5.5e+02 2.3 2.8 2 23 597 619 596 619 0.92
14 17 0.00031 0.03 15.7 1.7 1 23 625 648 625 648 0.98
15 17 2.3e-05 0.0022 19.3 1.3 2 23 653 674 652 674 0.96
16 17 0.0002 0.019 16.3 4.0 1 23 680 702 680 702 0.97
17 17 0.0008 0.078 14.4 2.1 2 23 707 729 706 729 0.96

Sequence Information

Coding Sequence
ATGCCGCCGGTGCAAGTACAATTTTATTTTTGTTTTCTAGGATCCGACACAAACCCTGACTCCACGCAGCCAAAGAGAAGGATAGTGCCGCTATTCCAAGTAGCGTACGATCGCAGCTTGTGTAGACCGCTGGGGACCGTCAGTGACTTCAGCAAATTGAGGAAAAAAGGATTCTCCACTTCACTAGATACCGTAACTTTCGTCGTATCACGAAGTCCGTCTCCTGTCTCACCCGCTAGGTCGCAGTCACCCTTCCAACTCGAAGACATAAACCCTCCAGCTGAGTTTTTAGTAAAACCGGAGCCAAAGAAAAAATGTTCCGACACCAGACAAAACGCTCTGACCATCTTCGAATTCTCAACTGCATACCCCTTCGTATTCTCAAATAACAAGTTCAAATGCTTCGTTTGCTCGCAGCCCTATCTGGACCTCGTCATCTTAAAACAGCATATGCAAGAACACACCTTCGCACCATTGAAACGACTTGTCAACAACAGGAAAGAAAACGTGCTCAAAGTTGACGTCAGCGATCTGGGTTGCAAACTCTGCACACTGCCAATCAACGATCTGATCACACTTAAACTACATCTGAAGGACTCTCACGGAAAACCAGTTGACACGGAACTGCAGGACAATTTGATACCATACAACTTGAATTCGGTTAACGATGGATACCAGTGTGTCATTTGTAAGCAGAACTTCATCAAGGTCCGAGTTTTGGTGATCCACATGAGCGCTCACTTCAGCAACTACAGCTGCGAAATCTGCGGTTCAGGGTTTATGACTTTACGGTTGCTAAAGAAGCATTTGGAGGTCCACGAGACGGGCAACTTTCCTTGTGATCGCTGCGACAAATCTTTTAGCACGAGCTATAAGCGCGCTTTACATATTAGAGGAGTTCATCTGAAACAGTATCCTCGTCGGTGTCCCATTTGTCCTGAAAGATTTAACTCCAATTACAAGAGGACTATTCACCTGCAAGATGTACACAACCAGTCTACGCGAGTGCACAAGTGCGAGACTTGCGGTCGAGGTTTCCACCTGAAGTACCACTTGATCTACGAGCCAATTAAAAGGCATAATTTTATTTTCCCAGGATCTCGAGCGTCACAGCGAAATCCCGAAAGAGAGGACAACGGACCCAGGACCAGTATATGGCACATGACAACGCCCGAACGCGAGAACGCTGCTACGTTCCTCGAATTTACAACCGTTCAGCCCTTTTTATGGCACCGAGGCAACTACAAATGCTTCTATTGCAACGAAACCTTCACCGAAGTGCATCCAGTCATACAGCATACAGCTACTCACGAGATTCCTAGCAGATCTGATCTATTGAACGAATATGTGAAGGTTGGCAAAAGAGTGGTCAAAGTTGACGTAACTGGTCTGAAATGCAGGATCTGTGATCTGAAATACTCAGAGTTGGATGATATTAGAAAGCATTTGATATCTGCACATAAGAAGGTGTTTAAAAAAGCTGGAAACGGCCTGATGGCTTACAATCTTAACGCTACCACAGGTCAGCTGTCATGCCATAAATGTGCAAGGGAGTTCACGTCTTTCTTCGCATTAAATCGCCACATGAACATTCACGACAATGTGGTCTGCGAAACTTGTGGCCTAGGCTTCATGACTTACCAAAGACTTAGGAACCATAGGATAGTCCACAGAGATGGCACATTCAAATGTGAGCAATGCGAAGAAGTGTTTACGACGAAAATGAAATTACGTTATCACGCCACCAAATGGCACGAAGAGACGAACGTAAAGAAGCTTAAGCCTCTGAAATGTGCACATTGTTTGGAACGTTTCAGCGAGCATTATAGAAAGATGGCTCATTTGAAAGAAGTTCACGGTATCACCTTCAAGTTTGAGTGTCACACCTGCAAGGCCGTCTATCCGACAAGGAGAGGTCTCACCGAGCACCAGAGAAAACTCCACATACAAAACATACAGTGCAAAATCTGCGGCAAGTGCTTCGGTACTACGGCTCAGTTAAAGATACATTCGCGAGGACATACTGGGGAGCGCAATTTCTTCTGCTCTGTCTGCCAAAAGGCGTATATGCATGAGAAGCTGTTACGGAAGCACATGAAAACCCACGGATTTGTATCCACGTGCTTACATTGCGGGAACGGGTTTATGAATAAGAGCGAGTATTACAAACATATGAGGCAGTGGCACAAGGACCTCAAGAAACCTAGAACTGCTGTTCCTAACTCAGCTTCAATCCCGAGTTAA
Protein Sequence
MPPVQVQFYFCFLGSDTNPDSTQPKRRIVPLFQVAYDRSLCRPLGTVSDFSKLRKKGFSTSLDTVTFVVSRSPSPVSPARSQSPFQLEDINPPAEFLVKPEPKKKCSDTRQNALTIFEFSTAYPFVFSNNKFKCFVCSQPYLDLVILKQHMQEHTFAPLKRLVNNRKENVLKVDVSDLGCKLCTLPINDLITLKLHLKDSHGKPVDTELQDNLIPYNLNSVNDGYQCVICKQNFIKVRVLVIHMSAHFSNYSCEICGSGFMTLRLLKKHLEVHETGNFPCDRCDKSFSTSYKRALHIRGVHLKQYPRRCPICPERFNSNYKRTIHLQDVHNQSTRVHKCETCGRGFHLKYHLIYEPIKRHNFIFPGSRASQRNPEREDNGPRTSIWHMTTPERENAATFLEFTTVQPFLWHRGNYKCFYCNETFTEVHPVIQHTATHEIPSRSDLLNEYVKVGKRVVKVDVTGLKCRICDLKYSELDDIRKHLISAHKKVFKKAGNGLMAYNLNATTGQLSCHKCAREFTSFFALNRHMNIHDNVVCETCGLGFMTYQRLRNHRIVHRDGTFKCEQCEEVFTTKMKLRYHATKWHEETNVKKLKPLKCAHCLERFSEHYRKMAHLKEVHGITFKFECHTCKAVYPTRRGLTEHQRKLHIQNIQCKICGKCFGTTAQLKIHSRGHTGERNFFCSVCQKAYMHEKLLRKHMKTHGFVSTCLHCGNGFMNKSEYYKHMRQWHKDLKKPRTAVPNSASIPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-