Basic Information

Insect: Alsophila aescularia
Gene Symbol: ZFX
Assembly: GCA_946251895.1
Location: CAMIUG010000072.1:1410874-1417655[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0076 0.74 11.3 0.8 2 23 266 287 265 287 0.96

2 18 0.075 7.3 8.2 0.1 2 23 328 350 327 350 0.94

3 18 5.5e-05 0.0053 18.1 1.8 2 23 372 393 372 393 0.97

4 18 0.00028 0.028 15.8 0.3 1 23 399 422 399 422 0.95

5 18 0.13 13 7.5 0.1 1 23 428 450 428 450 0.93

6 18 0.00018 0.017 16.5 0.9 1 23 456 478 456 478 0.95

7 18 0.047 4.5 8.9 2.1 1 23 617 639 617 639 0.97

8 18 0.00033 0.032 15.6 1.3 2 23 646 668 645 668 0.92

9 18 1.7e-05 0.0017 19.7 3.4 3 23 676 696 675 696 0.98

10 18 9.4e-06 0.00091 20.5 1.6 1 23 702 724 702 724 0.98

11 18 0.00087 0.085 14.3 0.2 1 23 730 752 730 752 0.97

12 18 0.00023 0.022 16.1 1.8 1 23 758 780 758 780 0.94

13 18 9.5 9.2e+02 1.6 0.0 2 23 871 891 871 891 0.88

14 18 0.00028 0.027 15.8 0.0 1 23 897 920 897 920 0.96

15 18 0.00084 0.082 14.4 6.4 1 23 926 948 926 948 0.98

16 18 0.0014 0.13 13.7 0.1 1 23 954 976 954 976 0.94

17 18 5.9e-05 0.0057 18.0 0.3 1 23 981 1003 981 1003 0.94

18 18 0.0062 0.6 11.6 1.1 6 23 1013 1030 1011 1030 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0076	0.74	11.3	0.8	2	23	266	287	265	287	0.96
2	18	0.075	7.3	8.2	0.1	2	23	328	350	327	350	0.94
3	18	5.5e-05	0.0053	18.1	1.8	2	23	372	393	372	393	0.97
4	18	0.00028	0.028	15.8	0.3	1	23	399	422	399	422	0.95
5	18	0.13	13	7.5	0.1	1	23	428	450	428	450	0.93
6	18	0.00018	0.017	16.5	0.9	1	23	456	478	456	478	0.95
7	18	0.047	4.5	8.9	2.1	1	23	617	639	617	639	0.97
8	18	0.00033	0.032	15.6	1.3	2	23	646	668	645	668	0.92
9	18	1.7e-05	0.0017	19.7	3.4	3	23	676	696	675	696	0.98
10	18	9.4e-06	0.00091	20.5	1.6	1	23	702	724	702	724	0.98
11	18	0.00087	0.085	14.3	0.2	1	23	730	752	730	752	0.97
12	18	0.00023	0.022	16.1	1.8	1	23	758	780	758	780	0.94
13	18	9.5	9.2e+02	1.6	0.0	2	23	871	891	871	891	0.88
14	18	0.00028	0.027	15.8	0.0	1	23	897	920	897	920	0.96
15	18	0.00084	0.082	14.4	6.4	1	23	926	948	926	948	0.98
16	18	0.0014	0.13	13.7	0.1	1	23	954	976	954	976	0.94
17	18	5.9e-05	0.0057	18.0	0.3	1	23	981	1003	981	1003	0.94
18	18	0.0062	0.6	11.6	1.1	6	23	1013	1030	1011	1030	0.97

Sequence Information

Coding Sequence: ATGGATACAGGTATTAGAAAAGTGTTTCTATTGAACTCAACTGAACAACATTTAACAACACCCTTGCAGCGGGCTTTTACGATGCCTGTGGCAGCAACGGAAACCGAAGATGCACCTGAAGCTACCACTATGTGTCCAGGGTTAACGCCCCACATGTGTCCCTCCCGGGGCAACATGTGTCGCCTTTGCGCCACAATCACAGAGTTTGTGGTGCCCATATTCGAGGGTGAGGGACTGCAGAATAGCCTTGCTGATAAGATCCATCAGCATCTACCAATACAGGTGTGCCAGGACGACGTGTTGCCAGTAGTGATGTGCTTCCAGTGCACAAGCACCCTGCTGGCGTGGCATGAGCTCGTGCTGTGCTCTGTGCAGGCTGACAACGCCATGCGAGAGAGATTCAATTTGCAATTCTCAGCTTCTCACCAGAGACGACAGCAACCAAACATTGAAGCTACCCAAAATGAAGATAAAGATGAGAAGTCACAAGCATTGAAAATTGTAAAAAATGTTTTGACCCAATACATGCACTCGCTAAACATGGGCGAGGATAGCTCCCACGTACAACTGGTCTGCCAGAAATGTGTCTCCAAACCGGGTTTCACATCGGAACACTTCACCGAACATTTGCACACACACCACCGCTCGGAAGTCTCCAACGAAGAAGCAACACTTAACTTCATAAAGGATCACGTCACATTCGAGGAACCACTGTTGTCAGACTCCGAGAGAGATGCAGATTCGGACGCGACGGAACAAGCACCAATATCTGAACCGAAACCTCTGCCCTCTCTACCCTGTCCGTACTGCGAGAGCGCGTTCTCGTCGACCACTCGCCTCGTCCACCATCTGAATAAGCACAGGAAGATATCCTGCAAGGAGGAAGTTGAATGTTGCGCTGTTCTTTACCGCACTAGGAAGGAATTTGCCGCGCATTTGCTGGAGAAACACGTTAATCGCACCATCCCCAATCCTGAGACTACGTGTAAGAGCTGCGGCCTCACCGCGGACTCCGAGGCCGAGCTCCGAGCTCACGTGCGGGACCAGCACGCGGAGAAACGAGACAAGAGGAAAAAGAAAGAGAGTGCAAAGAACCAGAAGTCGATCCCGGCCGTCTGTCCCGAGTGCAACAAGACATTCTCCAACAAATACAACATGTTCTTCCACATGAAGTCGCACGTGACTATTGGCATGCACCCGTGCGACCGCTGCGAGCGCGTCTACAGCACGCGTGGGAACCTGGCGCAGCACGCGCGACTGGCGCACGATGGCGAGCTACCTCACGCGTGCCCCGCGTGCGGGGAGGCGTTCGCGACGCGCACCGCTCGCGACGTGCACGCGCGCCTCCACACCGGGCTGCGCCCTTTCCGCTGCGAGCGCTGCGGGAAGCGCTTCCGGGCCAAGGACTCGCTCGACCGCCACACCGACGCACACCTAGACCTGCGGAGACACGCATGCGACGTCTGCGCCAAGGCGACGCTCGCGCCGAGCGGATGGAACGGAATCGCGACCGACGGCGGCCGATTCGAAAACGTGTTCGTGGACGACGCGGACTCGACCGACTCGGACGACCGGCCGTTGGCCGAGCTGGTCGCCGACGCGGCCGGGCCCGGCGCCTACCTCAGATTCTACGATGCGCTCGTCAAGTTCAGAGATCACGTGGTCGAGGAGCACGCGCGGCGGACGGACGCGAGCGACGCGGAGTCGAGCGCCGCGGTGGCCGGGGAGGGGAACGGGGGGGACGCGTACGACGATCTGTCGCACCGCAACATGCGGCGCGACCGCCTCGACGCTGGCACGCGCGCCGAGCTCGCCGCCGCGCGCGTGCCGCTCGACGGGAAGGTGCTATACGAGTGCCGCGAGTGCGGCAAGCGGCTCAGCTCCGCGCACACATACGTGTTCCACCGGCGCATCCACACGGGCGAGCGCCCGTGCGTGTGCCACGTGTGCGGCAAGCAGTTCCGCGCGCCCAACGGGCTGCAGCGACACTTGGCGGAGACGCACGAGCGCCGCCGGCGCCCGGCGTGCCGCCATTGCCGCCGCAGCTTCGCCAACTCGCAAAACCTGAAGCAGCACATGCGCATCCACACCGGCGAGCGGCCCTTCGAGTGCGCGCGCTGTGGCAAGCGGTTCGCGCAGTCGGGCTCACTGCATGCGCACCGCAAGACGCACTCGCCGAGCAAGCCGCACCGTTGCGCCGAGTGTGGCGCCGCCTTCCGCCTGCGAGCCGGGCTCGCGCGCCACCGCCTGCGGCACACCGGGGAGCGCCCGCACGCGTGCGACCTATGTGGCAAGCGCTTCCGGCAGCGGCATGAGCTCGGCGCGCACCGCCTCGCGCACACGGACGTACGCCCGCACGCTTGCGACCTGTCCCCCGCCGCCGCCGCCGCTCTACGACCGCGCCGCGCCCTACTGATCTCCCTCGGTTCGAACCCGCCCTCGCTAACGATCCTCGCTCTGGGACGCGTCGTCTCTCACTCCGTCGTGTGCCTTTCCAGAGCCGATGCGGAGCGCGAGGTGAAGCTCGAGGCGGACGAGGCCGGCGAGGAGCCCGACGAGCTCGCCCGCCCGAGCGCCATGCTTTTCGGCGCCGATGGCAAGAGGTATGCGCGGTGCGGCGCGTGCGACAAGACCGTGGCGGCGGCGGCGTGGCGTCGGCACGCGCGTTCGCACTCGGGCGCGCGGCGCTACAGCTGCCACGCGTGCGGGCGCGCGTTCGCCGACGGCGGCAACCTGGCGCGGCACGCCCGCGCCGCGCACGGCGAGCGCCGCCCGTTCTCGTGCTGCACGTGCGCACGGAGCTTCACGCGGAGGGAGCACCTGCGCGAGCACGAGCGCACGCACGCGGCGCGACGCGAGTTCCTCTGCGACGTGTGCGGCAAGGCCAGCAAATCGGCCGCGGCGCTGCGCATGCACCGCGCCTCGCACGCGCCGCGCCTGCACGCGTGCGTTGAGTGCGGCGCGCGGTTCAAGCGGCGCTCGGAGCTGCGCGCGCACGCGAGCGTGCACTCCGGCGAGCGCGCGCACGCGTGCTCCTGCGGCCGCACCTTCCGGCTTCGCGGGCAGCTCACCGCGCACCGCCGCGCGCACGCGCCGTGCCGCGCGCCGGAGAGCGTGCCTTGA
Protein Sequence: MDTGIRKVFLLNSTEQHLTTPLQRAFTMPVAATETEDAPEATTMCPGLTPHMCPSRGNMCRLCATITEFVVPIFEGEGLQNSLADKIHQHLPIQVCQDDVLPVVMCFQCTSTLLAWHELVLCSVQADNAMRERFNLQFSASHQRRQQPNIEATQNEDKDEKSQALKIVKNVLTQYMHSLNMGEDSSHVQLVCQKCVSKPGFTSEHFTEHLHTHHRSEVSNEEATLNFIKDHVTFEEPLLSDSERDADSDATEQAPISEPKPLPSLPCPYCESAFSSTTRLVHHLNKHRKISCKEEVECCAVLYRTRKEFAAHLLEKHVNRTIPNPETTCKSCGLTADSEAELRAHVRDQHAEKRDKRKKKESAKNQKSIPAVCPECNKTFSNKYNMFFHMKSHVTIGMHPCDRCERVYSTRGNLAQHARLAHDGELPHACPACGEAFATRTARDVHARLHTGLRPFRCERCGKRFRAKDSLDRHTDAHLDLRRHACDVCAKATLAPSGWNGIATDGGRFENVFVDDADSTDSDDRPLAELVADAAGPGAYLRFYDALVKFRDHVVEEHARRTDASDAESSAAVAGEGNGGDAYDDLSHRNMRRDRLDAGTRAELAAARVPLDGKVLYECRECGKRLSSAHTYVFHRRIHTGERPCVCHVCGKQFRAPNGLQRHLAETHERRRRPACRHCRRSFANSQNLKQHMRIHTGERPFECARCGKRFAQSGSLHAHRKTHSPSKPHRCAECGAAFRLRAGLARHRLRHTGERPHACDLCGKRFRQRHELGAHRLAHTDVRPHACDLSPAAAAALRPRRALLISLGSNPPSLTILALGRVVSHSVVCLSRADAEREVKLEADEAGEEPDELARPSAMLFGADGKRYARCGACDKTVAAAAWRRHARSHSGARRYSCHACGRAFADGGNLARHARAAHGERRPFSCCTCARSFTRREHLREHERTHAARREFLCDVCGKASKSAAALRMHRASHAPRLHACVECGARFKRRSELRAHASVHSGERAHACSCGRTFRLRGQLTAHRRAHAPCRAPESVP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -