Apic011392.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Alloplasta piceator
Gene Symbol
topi
Assembly
GCA_946863875.1
Location
OX333074.1:15135362-15138987[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.5 2e+02 3.4 0.4 1 23 255 277 255 277 0.90
2 16 0.26 34 5.9 4.9 2 23 284 306 283 306 0.95
3 16 0.00065 0.086 14.0 0.5 2 22 313 333 312 333 0.94
4 16 5.7e-06 0.00074 20.5 0.8 1 23 340 362 340 362 0.97
5 16 1.3e-06 0.00018 22.5 2.1 1 23 368 390 368 390 0.97
6 16 0.0055 0.73 11.1 0.7 2 23 402 424 401 424 0.95
7 16 2 2.6e+02 3.1 3.4 1 23 441 463 441 463 0.97
8 16 0.0084 1.1 10.5 0.1 1 23 469 491 469 491 0.96
9 16 0.0029 0.38 12.0 0.8 1 23 501 525 501 525 0.92
10 16 4.4e-05 0.0057 17.7 0.2 1 21 540 560 540 561 0.94
11 16 0.0074 0.97 10.7 0.0 1 23 566 588 566 588 0.98
12 16 2.2e-06 0.00028 21.8 3.1 1 23 594 616 594 616 0.98
13 16 0.00014 0.018 16.1 0.4 1 23 622 645 622 645 0.97
14 16 0.052 6.9 8.0 0.7 1 23 651 673 651 673 0.89
15 16 3.5e-07 4.5e-05 24.3 2.2 1 23 679 701 679 701 0.99
16 16 6.6e-06 0.00087 20.3 4.9 1 23 707 730 707 730 0.96

Sequence Information

Coding Sequence
ATGGAGAGCACACTCATAGCCGATTCGATAAACGCGACCATGAGCGACAGAGAGGATTACATGAACGACGTTGAAGATATAGATATTATTTGGTCGCAGGAAGATCTACTCCCGACGAGTAACGAACCGGAAACAAAATGCATATCGAACGGCGACGATGAGACTTCGGCCCTTTGCAGATTGTGCGCTGGCCAAGCCATCAATCCCGTTTACATTTATTCAGAATTTGGAGAATCCATGAAGCTTGCACAGAAAATAAATACATGCTTGAGCACAAAGATCAGAAGAACGGATCCTCTTCCCAAGCAATTGTGTCATATCTGCGTTGAGAAGATAAATTGGTGTGACTCGTTCGATGTCGATTGTATGAAGGCCGAAGAGACCCTCGAGACGATGCTACGAGACGAGATGTCAGAAACGCCGGATATCGCGATACCGGAAGTAACTCGCGACGACGCCGAAACCAGCTGTCCTCTGTGCGTCGAAGGTCAAATGCGAGAGAGTCACCCGAACCCTTCGTCATTTCCGACGAATCTTCAATCGGATCTTTACGACAGCGACATTGTGATGAACAGCGACGACGAGGAGAAAGCATTGTCGATCGTGAATTCGGAAAAACGTGAATCCGACAATTTGATCAATCGTCAGAGCAACAACAGTCAGCGCTACATAAAATGCGGCGCTTGCATGAATCTCTATCACACGCGCGAGAGTCTCGATTCGCACAAATGCAAACCCAACATTCAAACGACAACGAAGCCTTACAAGTGTCTCGTTTGCGAGGCGACTTATCCCTTCGAGGAATTGCTGAACTTTCATGTGAAATTTCATCAAGGCGCGACGGAGCTTCACTGCGACATATGCAAGATAAATTTCAGCAAGGAATTGAAGCTCTATCATCATTACAAGCGTTATCACTGCGAGGATCGCAGCGTCTCGTGTCTTCAATGTGGCAAATTATTCGTCGATCAGCAAGAATTGCGACAGCACATTTGCACAGACGGCAAAACGCGTCCTCACGTTTGTGATATTTGCAACAAAGGCTTCTCCGACGGTTACACCCTGAAGCGTCACATCGTGACTCATCTGCCGGAAAAACCATACAAGTGTTCTCAATGCACCAAGAGTTTTACCCAAAAATCACGCTTGAACAAGCACATTGCGGCTCACGGCGTCGTCATCGAGAATACCCAGATCGTTTGTGTGTGTCTGAAATGCGGCGAGATATTCGTCGACAATGCGGAAACGGAAAATCACAATCGGACGAAACACAATGACGATGAAGCGTGTCTGATCCAGGAAATAACGACGTCAAAGATTTATCATTGCGAATTTTGCAACAGTCATTACAATGACCTCGATATTCTGCGTGAACATCAGAATCTTCACGTTGTCGAGAAACCCTACACGTGCAATATATGCGACAATGTTTACAAATCATACGCCGAGGCCGTTCAACACTGGAAGGAGCATCCTCGAATTTTTCGCGTTGCAATTGCCTACATGTGCGATATCTGTGGCAAGGACATGAAGGACATGTCACTGCTGTACAAGCATAAGCGCAAGCGAATTCACGCGAACGCTCGAAAATCGGAAAATTCGGAGGTTACCAAGAAAtacgtttgcgaattgtgcggcaaatgtttcgagaacgtcgatgacttgcgagttcacggcagagatcaatgctccaaatttccatgcgacatatgcggaggtcttttgccaacggcgaattcgctgaacgctcacaagagacgacacagcggtttgcgtccctacgtttgtaacatatgcggcaaaagttacacccaatcgagtcacatgtggacccacaagagatttcacatgggcgttaagccttacgcctgtgaatattgcgatcagaggttcacgataaagcccgatctcgctgatcacaccaggaaaaagcacacccgcgagagacccttcaagtgcgacgtttgcaacaaggcctttctcacgggctccgttttttatcagcatcgtttgattcatcgcggtgacagacgctacaagtgtcactattgcgagaaagcattcacgagaaccgaagctctcaacaatcatattaaaatacacaccggcgagaaacctcacgcttgcgacgtttgcggcagatgcttcagacaaaagggcgatatgaggaaacacaggagaactcaacatgctgTAAATAAAGAAGAAATTCCGCAAGGATGA
Protein Sequence
MESTLIADSINATMSDREDYMNDVEDIDIIWSQEDLLPTSNEPETKCISNGDDETSALCRLCAGQAINPVYIYSEFGESMKLAQKINTCLSTKIRRTDPLPKQLCHICVEKINWCDSFDVDCMKAEETLETMLRDEMSETPDIAIPEVTRDDAETSCPLCVEGQMRESHPNPSSFPTNLQSDLYDSDIVMNSDDEEKALSIVNSEKRESDNLINRQSNNSQRYIKCGACMNLYHTRESLDSHKCKPNIQTTTKPYKCLVCEATYPFEELLNFHVKFHQGATELHCDICKINFSKELKLYHHYKRYHCEDRSVSCLQCGKLFVDQQELRQHICTDGKTRPHVCDICNKGFSDGYTLKRHIVTHLPEKPYKCSQCTKSFTQKSRLNKHIAAHGVVIENTQIVCVCLKCGEIFVDNAETENHNRTKHNDDEACLIQEITTSKIYHCEFCNSHYNDLDILREHQNLHVVEKPYTCNICDNVYKSYAEAVQHWKEHPRIFRVAIAYMCDICGKDMKDMSLLYKHKRKRIHANARKSENSEVTKKYVCELCGKCFENVDDLRVHGRDQCSKFPCDICGGLLPTANSLNAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHAVNKEEIPQG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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