Apic026145.1
Basic Information
- Insect
- Alloplasta piceator
- Gene Symbol
- lola
- Assembly
- GCA_946863875.1
- Location
- OX333080.1:2210951-2221651[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.011 1.5 10.1 0.6 1 21 74 94 74 95 0.95 2 18 0.015 2 9.7 3.6 1 23 103 125 103 125 0.97 3 18 0.23 31 6.0 1.7 6 21 167 182 165 183 0.93 4 18 1.8e-05 0.0024 18.9 2.0 2 22 192 212 191 212 0.95 5 18 0.00026 0.035 15.3 0.9 1 21 241 261 241 262 0.96 6 18 0.00026 0.035 15.3 6.5 1 23 270 293 270 293 0.96 7 18 0.00024 0.032 15.4 0.3 1 21 316 336 316 337 0.95 8 18 0.064 8.4 7.8 4.5 1 23 345 369 345 369 0.90 9 18 0.0013 0.17 13.1 0.4 1 19 394 412 394 414 0.94 10 18 0.049 6.5 8.1 2.4 1 23 432 455 432 455 0.96 11 18 5.3e-05 0.007 17.5 1.4 1 21 461 481 461 482 0.94 12 18 0.022 2.9 9.2 0.8 1 21 490 510 490 514 0.91 13 18 0.013 1.7 10.0 0.2 1 21 545 565 545 566 0.95 14 18 0.00014 0.019 16.1 3.2 1 23 574 597 574 597 0.97 15 18 5.3e-07 6.9e-05 23.8 0.5 1 21 629 649 629 650 0.95 16 18 4.7e-05 0.0062 17.6 1.2 1 19 658 676 658 678 0.96 17 18 1.2e-05 0.0016 19.5 0.8 1 20 714 733 714 735 0.95 18 18 9e-06 0.0012 19.9 0.5 1 23 743 766 743 766 0.95
Sequence Information
- Coding Sequence
- ATGACGATGTCGATGGGCTGGCTGCGCTGTCACTGCGGTCGTCGTTTCAAGCACGAATTCTCGCTGAGCTGCCATCAGCACAACGAGTGCGGTTTCGATTATCAGTGTCTCAATTGCGCGTTCACCACCGACAAGCTGTATCTTTGGCTGGAGCATACGAAGAAACTATGTCCCGGAAGATTCGGGGCTCCTCGCTATTTTATACTTCTGGACAAACCATTTATCTGCGGACGTTGCGGACGAAGTTACAAGTGGAAAACCTCGTTGAAGTATCATCAGAGGGACGAGTGCGGCAAGGATCCGCAATTTCATTGTCGCTACTGCGGTTACAGAACGAAGATACGATCGAATTGGATAAGACACGAGAAAAATCACACAAAGCAACCGACGGAAAAGTTTCGGCCGACTTATCCAATGGACGAGAGGAATAGTCGACCTTTTCTACGCGTGAAAAATCGCATCAGACGTGTCCCTCAAAGGATGAATTATTCGTGCCGATGTGGTAGAAAATATTCGCAAAAGTGTTCCTTGGATCGTCACGTTAAGTACGAGTGCGGCAAAGCGCCGAGTGTGCCTTGTCCGAATTGTGGAAAAATGTTCAAGCATCGTCATCACGTTATGGAACACATGAGAAAGTACTCCTCGAGATTCCGGCTGCACTACGAGCAATTCGCGTCCCAACAAATGGCGGATATGATGTCAATGCAGACTGAGAGAAAATTTACTTGCGATAATTGTGGAAAATCATACAAGTGGAAGGAATCGTTGTTCAAGCATCGTCGCATCGAGTGCGGCAAAACACCACAATTTCCATGCGACATATGCGGTCATCGTTTTATGCACAAGCATCACTTGATCAAACATTTATCGTCGATTCATCAAGTCCCACCTGCACTTGGCACTGACGTTGTGATCATTCCTCGTCAACGAAGTGGAAAACAATCGTACGCGTGTACTAATTGTGGAAAATCGTATTACGCGATGGATTCATTGAGGCGTCATCGACGTGTCGAGTGCGGCAAACCGCCGAGATTTGCCTGCACGATGTGTGCCGCACGATTTATGCACAAGCATCATCTCATCAGTCATCTTAATTCGAATTATCACACGACCAACGCGAATGGAGCCATGGAATTCAAGATCGAGAACGTCATGAGCTGTTTTATTCAAGATCCGTCGCACTCGTGCCCGCGATGCGGAAAGGGATTTACATCGAAACGTTGGATGTTGAATCACAGTGCGAACGCGTGTCAATTATTCATCGATCGTAAACGTGACGAGGCATGGCGTAAATTTCCTTGCAGACTATGCGAGGCGCGATTTTTCGAAAAGCATCATCTGGCAGCGCACGAGAATTCATACCACAACGATGACAAAAATCATGTTTGCGAGGATTGCGGTAAAAGTTTTTCGTGGAAATCGTCATTCAATCGTCATCGCCAGCGCGAATGTGGCCAAAATTCGGATTTCACTTGCGAAACTTGCTTGGCGAGTTTCCCCACCAAGCATGGCCTCCTCCTTCATCTTTCGGAGAGTAAACACTCGCAGAACGATTTCATCAACGCGTACCCATCCCGAACGCGATACTTCGCTGGAAAATCACGCTCCGGGCATTCGTCGTACAACAAGCCCCACGTGTGTTTGACCTGCGGAAAATCTTACATCTGGAAAATATCTCTCTCGAGGCACATTCGCGACGAGTGTGACAAGGCGCCGCAATATTCGTGCATGTTTTGCGCCCGAAGTTTCAAATCTCGCAGCAGTTTTCAGCGTCATCTGAGTACTCAGCACAATGCTCGATTGCCGAGACCGAGTCTTCCAGGTTCGTCACAATCGCCGGCTAAGATAATCGGCGTTCCAAGGCAGAAGCAACTTTGGCGCCCATTTCCTTGTTCCGTTTGTGGAAAATCGTACACGAGGAAGGACACCCTGAGGCGACATGTGCGCTACGAGTGCAACAAAAATCCTCAATACATTTGCTATGTGTGCAAGAAAGGCTTCAAGCAAAAATCAAACTTTCAGCGACACAATGCTAACATATCCAAGAGGCTCCATGGAATTGGAGCGAAAAAAAACAATATCGCAGGCAATAGATCGTCACGAAGACACGGGCGCGGCTATGGGAATTTCGATAATCCTTATCCCTGTGTAAAGTGTGGAAGATCGTACAGAAACAAGGGAAGCCTCAAGCGTCATCTTCACGACGAGTGCGGCAAACCACCGAAATACATATGCAGCGTTTGCGAAAAGGGTTTCAAGCAGAAAGCGAATTTTCAGCGTCACAGCGCAACGATACACGGCCATCTTTTTTCCCTGAGATCATGA
- Protein Sequence
- MTMSMGWLRCHCGRRFKHEFSLSCHQHNECGFDYQCLNCAFTTDKLYLWLEHTKKLCPGRFGAPRYFILLDKPFICGRCGRSYKWKTSLKYHQRDECGKDPQFHCRYCGYRTKIRSNWIRHEKNHTKQPTEKFRPTYPMDERNSRPFLRVKNRIRRVPQRMNYSCRCGRKYSQKCSLDRHVKYECGKAPSVPCPNCGKMFKHRHHVMEHMRKYSSRFRLHYEQFASQQMADMMSMQTERKFTCDNCGKSYKWKESLFKHRRIECGKTPQFPCDICGHRFMHKHHLIKHLSSIHQVPPALGTDVVIIPRQRSGKQSYACTNCGKSYYAMDSLRRHRRVECGKPPRFACTMCAARFMHKHHLISHLNSNYHTTNANGAMEFKIENVMSCFIQDPSHSCPRCGKGFTSKRWMLNHSANACQLFIDRKRDEAWRKFPCRLCEARFFEKHHLAAHENSYHNDDKNHVCEDCGKSFSWKSSFNRHRQRECGQNSDFTCETCLASFPTKHGLLLHLSESKHSQNDFINAYPSRTRYFAGKSRSGHSSYNKPHVCLTCGKSYIWKISLSRHIRDECDKAPQYSCMFCARSFKSRSSFQRHLSTQHNARLPRPSLPGSSQSPAKIIGVPRQKQLWRPFPCSVCGKSYTRKDTLRRHVRYECNKNPQYICYVCKKGFKQKSNFQRHNANISKRLHGIGAKKNNIAGNRSSRRHGRGYGNFDNPYPCVKCGRSYRNKGSLKRHLHDECGKPPKYICSVCEKGFKQKANFQRHSATIHGHLFSLRS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -