Basic Information

Gene Symbol
zfy1
Assembly
GCA_932294395.1
Location
CAKOAO010000223.1:132386-133819[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.028 1.8 9.6 2.8 2 23 158 179 158 179 0.98
2 11 0.00028 0.018 15.9 0.7 1 23 185 207 185 208 0.95
3 11 9.4e-06 0.00062 20.5 0.4 1 23 215 237 215 237 0.98
4 11 5e-05 0.0033 18.2 0.9 1 23 243 265 243 265 0.98
5 11 2.8e-06 0.00018 22.2 3.6 1 23 271 293 271 293 0.97
6 11 5.9e-06 0.00039 21.2 4.2 1 23 299 321 299 321 0.99
7 11 1.5e-06 0.0001 23.0 0.3 3 23 329 350 328 350 0.97
8 11 0.0017 0.11 13.4 0.6 2 23 356 374 355 374 0.85
9 11 0.00011 0.0069 17.2 0.9 1 22 380 401 380 403 0.90
10 11 0.022 1.5 9.9 1.1 1 23 409 433 409 434 0.95
11 11 6.6e-05 0.0043 17.9 4.8 1 23 440 463 440 463 0.97

Sequence Information

Coding Sequence
ATGGAGTCAAAAATATGCCGCATATGTCTCAAACAAACGGCAACAATGTCATTATTTGATGAACAGGACGACATTCAATACAGCACAAAAGTGATGCGGTGTGTCAATGTGGTGGTGGTGGAAGGTGATGGGCTTCCAGGCTCCATATGCACGAGCTGTGCGGCAGAACTGGCCACGGCCTACGAGTTCGTGAACAGGTGTGAAGCGTCCGACAAAGCCCTCCGCTGTATCAACATAGCAGACCTTTATAACGATATGGTGCCAAAAACTGAACCACAAATCAAAACAGAAGACATCAAAGAAGAAAGCGAACCTGACTATCATGACCATTATGAAGATTTCCTATTAGAAAACCCCAAGGACTCCTGTGATATTAAAGATGGtaagaaacaaaaaaggaaGTATACAAAGTCTGAAAAGTTTAGAGATAACATCGATAGGCGGAAATTACGGCCTAAAAAGGGGCCAGCAAGGTGTACAGTTTGTGGTCACATGGCATCATGTCAGTCCGCCTTGGAGAGCCATTTGAGGACACATACCGGAGAGAAACCATTTATTTGTGACTCCTGTGATGCACGGTTCAACATCAAAGGTTCTCTCAAAAGACACATACTGATACATCATACTCAAAGAGAACGGAAATTCATTTGTGAAACATGTGGCAAAAGTTTTTTCTCTAAGAATGATATCATAACGCACATTAGAGTACATACCGATGAGAGACCATACTCTTGTTCATTCTGTGGCCGAGCATTCAGACAGATTGCATCAATGATACGTCACAAGCGCAATCACACAGGTGAAAGACCTTTTTCTTGTCCAATCTGTTTAAAAACATTCAAGGACAAAAGTCATATGAGAAGGCACCAGTATGTACACTCTGATGAGAAGAACTTCACGTGCCACCTGTGCAGTAAATCTGTTAAAACTAGAAATGCTCTCAAAACTCACATGCGGACACATTCCAATGAAAAGCATAACATCTGTAGTTACTGTGGTATGACATTCTCTTTGAAGGGTAATCTTCAGGTTCATATAAGGAGGATGCACTCGGAGAGGTCCGGTCAGTGCAGCATTTGTCTAAAGACATTTTCTGATTTAGAGGCACACATGCGCAAGCACACAGGCGAGAAACCATTTATATGTAAGCTTTGTGATCAAGGATTTGCAAGCAAAAGAAGTTTGACAAACCATATGGGCTTTAAACACGAGAATGCTTCAAAGTTCAAATGTTCTATAGGAGAATGTACTAGGACATTCCCTACTGCTATGATGTTGGAGTTCCACCTTCTGAAGCACCATACTAATCACACTCCATACATCTGCCACCATTGTTCCAGAGGATTTTTTAGGACCAGTGATCTATCTCGGCACCTCAGAGTCAGCCATATGGAAACACCTACAGTAGAATCTCGAATATCCAAACCTCGGTAA
Protein Sequence
MESKICRICLKQTATMSLFDEQDDIQYSTKVMRCVNVVVVEGDGLPGSICTSCAAELATAYEFVNRCEASDKALRCINIADLYNDMVPKTEPQIKTEDIKEESEPDYHDHYEDFLLENPKDSCDIKDGKKQKRKYTKSEKFRDNIDRRKLRPKKGPARCTVCGHMASCQSALESHLRTHTGEKPFICDSCDARFNIKGSLKRHILIHHTQRERKFICETCGKSFFSKNDIITHIRVHTDERPYSCSFCGRAFRQIASMIRHKRNHTGERPFSCPICLKTFKDKSHMRRHQYVHSDEKNFTCHLCSKSVKTRNALKTHMRTHSNEKHNICSYCGMTFSLKGNLQVHIRRMHSERSGQCSICLKTFSDLEAHMRKHTGEKPFICKLCDQGFASKRSLTNHMGFKHENASKFKCSIGECTRTFPTAMMLEFHLLKHHTNHTPYICHHCSRGFFRTSDLSRHLRVSHMETPTVESRISKPR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00017562;
90% Identity
iTF_01342411;
80% Identity
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