Basic Information

Insect: Aleochara curtula
Gene Symbol: ZFHX3
Assembly: GCA_963978815.1
Location: OZ022217.1:11558598-11566711[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.2 1.2e+02 3.3 0.1 1 21 72 92 72 95 0.78

2 15 0.00047 0.047 14.0 0.2 1 23 108 131 108 131 0.96

3 15 0.27 27 5.3 4.6 2 22 232 252 232 255 0.90

4 15 0.12 12 6.4 1.3 3 23 269 292 267 292 0.87

5 15 0.0013 0.14 12.6 1.3 1 23 310 332 310 332 0.97

6 15 0.00051 0.051 13.9 0.7 2 23 339 361 338 361 0.94

7 15 0.00065 0.065 13.6 3.2 1 23 468 492 468 492 0.92

8 15 0.004 0.4 11.1 0.6 1 22 512 533 512 536 0.89

9 15 0.0008 0.08 13.3 0.2 1 23 607 631 607 631 0.93

10 15 0.034 3.4 8.2 0.0 3 21 704 722 702 723 0.94

11 15 0.24 24 5.5 2.5 2 19 843 860 842 865 0.90

12 15 8.5e-05 0.0085 16.3 2.5 1 23 1461 1483 1461 1483 0.99

13 15 0.0012 0.12 12.7 0.6 1 23 1573 1595 1573 1595 0.98

14 15 0.0046 0.47 10.9 0.4 2 23 1744 1766 1743 1766 0.96

15 15 1 1e+02 3.5 3.2 3 23 2031 2053 2029 2053 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.2	1.2e+02	3.3	0.1	1	21	72	92	72	95	0.78
2	15	0.00047	0.047	14.0	0.2	1	23	108	131	108	131	0.96
3	15	0.27	27	5.3	4.6	2	22	232	252	232	255	0.90
4	15	0.12	12	6.4	1.3	3	23	269	292	267	292	0.87
5	15	0.0013	0.14	12.6	1.3	1	23	310	332	310	332	0.97
6	15	0.00051	0.051	13.9	0.7	2	23	339	361	338	361	0.94
7	15	0.00065	0.065	13.6	3.2	1	23	468	492	468	492	0.92
8	15	0.004	0.4	11.1	0.6	1	22	512	533	512	536	0.89
9	15	0.0008	0.08	13.3	0.2	1	23	607	631	607	631	0.93
10	15	0.034	3.4	8.2	0.0	3	21	704	722	702	723	0.94
11	15	0.24	24	5.5	2.5	2	19	843	860	842	865	0.90
12	15	8.5e-05	0.0085	16.3	2.5	1	23	1461	1483	1461	1483	0.99
13	15	0.0012	0.12	12.7	0.6	1	23	1573	1595	1573	1595	0.98
14	15	0.0046	0.47	10.9	0.4	2	23	1744	1766	1743	1766	0.96
15	15	1	1e+02	3.5	3.2	3	23	2031	2053	2029	2053	0.89

Sequence Information

Coding Sequence: ATGCGTAGGATAGCAATTGCGTTTGATGCATGTCGCAGCGCATATTTTATGTGTCTTCTTGTGTTTTCTGTGTCCCTTGCGTTCGTACGCAATGCAGAACGAAGAGACAGCGTCAACTCGGAGCAATCGAGCCAGGCGGATCAGAGCAAGGAGTTCAAATCGGAGCCTTGCGATGACAACGATGATCCAATGATACGCGACGCCGGAGCTCAGCATGTGTGTCCGTATTGCGATTACGCGAGCGACTCCGAGATGCGCATCCAAGCGCACGTGTTGGCGCAGCACGGtacaagcaataataatagttcCTCGGAGGCGAGCTTTCAGTGTCCGCTCTGCCAGGACGCATTCAAAGACAGAACTAGTCTGGAGCGGCATGTCATGCAAATACATTCGGTCAACAGCGAGGGCCTGCAGCGCCTGCTAATGCTCGTCGATCAGAGCCATTGGCTGAATCAGGCGTCGCGCACGCCAACCCCAAACAATGCGGCCGCGCACCATCCGCAGATGCCATCGAATCAGATGGTGTCGCCGAACTCTGTATCTTCCAAAGACTCCGCCAAGCTCGATAAGAGCGATACCGCGCCGCACAATAACAGCAGTAGCGGCGTGGACATGGAGAACGAATTAATGTCGCCGCATAGCGTAGGCGGCGCGAGCAGCGACGTCGATGCCGGCGACCTAGAGCTGGAGCGGTGCAATACGTGCATGAAGTGTTTTAAGAACATCGACGAGCTGTGCCTCCATCAGAACGAGACCGGCCACTTGGAGATCAAGCAAACGCCGAGTGGGCCTGGCTACCTGTGCTGGAAGAAGGGCTGCAATCAGTTTTTTCCCACCGCGCACACGCTGCAGATGCACTTCAAGGAGGTGCACGCGAAGAACTCCATCTCTCAGATGTCCGTCTCCGAGAAGCACGTGTACAAGTATCGGTGTAATCAATGTTCGCTGGCGTTTAAGACCCTCGAAAAGCTGCAAATCCACTCGCAGTACCATCTCATTCGCGACGCAACCAAATGCGTTCTGTGCGGTCGCAGCTTTCGGTCGCTGGTTGCGCTGCACAAGCACGTCGAGAGCGTGCACTCGGAGCTCACCGACGAAGAGCTCAACGCGTACAAACAGAGCCTGATGAACAACCCGCTGCTGCTCGCTGGCCTCCAGGGCCAAGTGCTGGACAGCTCCACGAACGACATCCTCAAGAAGGAGTCGATGCGCGCCGACGACGGCGAGTCGCTCGAGTGTGACGATAGCAAAGAGTTGAGCACGAGCCACGACGATAGCAACGCCAACGATGGCGAAAACTCGGACGATAGCATCGTGTACAAAGATCAGCAGTTCCTAGAAGATTACCTGAATAGCCAGGCGATTGCCGAAGACAGCTACAACGACCCGAACCGCAAGTACAAATGCCACCGCTGCAAGGTAGCATTCACGCGACAGAATTACCTCACCGCCCACAACAAAACCCTTTTGCACCGCAAGGGCGAGAAGCTGAGCTACCCGATGGAGAAGTATCTGGACCCGAATCGCCCCTATAAGTGCGACGTGTGCAAAGAGAGCTTCACGCAGAAAAACATTCTGCTCGTGCACTACAATTCGGTGAGTCACCTGCACAAGCTGAAGCGCGCCATGcaagagcagcagcaacagcagaataataacaataacaatccACCCGTGTCGCCGGTCACGGCCGGCGGTACAACCagtgctggtggtggtgctggtggCATTGGCGGTGCGCTCGGGCAGCAGCCGCAGTCGCAGTCGCTCACCCCGAAGAGCACGTCGTCGAGCGACGAGGATGATAAGAAGCGCTATCGCTGCAACATCTGCAAGGTGGCGTACACCCAGGGCAGCACGCTCGACATTCACATGCGCAGCGTGCTGCATCAGACGCGCGCGAGTAAATTACAAGACTTGGCGATGGCCGGGCAGATCGACTTGTCGAAGCCGTTAATTGAGCAGCCCGAAGCCATGCAGTCTCCGAAGCAATCGAGTCCGACGCCGGCCGCGGGCAGTGGTGGGGAGAAGACATCTCCCACCCCGCCGTCGCCTAATCCCTCAGGTACACCAACAATAGCAGCAGGTAGCCAAGGGATGATGGCGTGCCCCAAATGCGGCGCGCTGTTTAGCGCGCCCGATCAGTTGAGTGTACACCAGCAGTTGTATTGCATGTTTGCCGCTCCGAATATGGCCATCTTTCAGGCGCAAGAGCCTGGCCTGGCGAAGAGCcctccgccgccgtcgtccAGCGGCGGCGAGACAGACGCGCTCGGGCGCATCAATCTACCAAAGAGAATCAATTCGCAAATGCAGAAACACTTGCTCGAGAGCTACGGCTTCGACGTAGTCATGCACTACAATGAGAGCCAGCAGCGACGCCACCGACACCGCGAATCCGCCGACCAGCGGACGTCTccgcctgccgccgccgccgccaatgtcACCGACGACTCCGCCGCCGACGCGACAGCGCGGCCCGAGGAGGAGCTCGATGCCAACTTACCCGAAGTAAGTAAATCCACGTGCCAACATTGCAATAAAGAGTTCTCTAGTGTGTGGGTGTTAAAGTCTCACTGTGAAGAAGTACATAAAGATTTAGTGCCGCTAGAATTCTTAGAAAAGTATGCTCAACAGTTCAAGAGTGAATATGAAAAGAAAACGGTGGTGGTGACCGCGGCGACCTCATCGACGACGCTAAACAGCCATCCACGCGTCTCGACGCCGTCAGCCGcgagcggcagcggcggcaatccgaatcacaacaacaacaccagcaGCCACCACACGCTGCCCGCAGACGTCGTCACGCCTGAGAAGGATGACGAATCGAAAGAGGCGCTGCACGCCAAGCTCAACCTGCAGACGCCGCCCGAGGCGACCTCGACGGCGCCGTCGACGCCAACGTCGTCCTCGACGCCGGCGAGCAGCACCGACTCGCTGCCGGCCAATATCCAAGCGATGATCGCGCAAACGATGGCTCAGAATCCGATGGCCTTGGCGCAGCAGATGACCGAAATGCAGGCGGCGCTCAATGTGATGcagctgcagcagcagctcaACTTCAATccgatgatgcagatgatgggCATGGGCCTGCCGCTCGGCCTGAACGCGCTCGCCGCCATGAACCTGCAGCCGCCGCTCGTACCGCTCatgatgccgccgccgccgttcgaCGCCATGCAACAGTTCGCGccgcaggagcagcagcaggcgaTGATGGCCGCAAAGCAGCAGCAAGCCGCGCTCATGCAACAGCAGGCAGCAGCGGTTAATGCGGCTGCGAACAACCAGAAGCGTGCACGCACGAGAATCACTGAcgatcaattgaaaattttgcgTGCGCATTTTGACATAAACAATTCGCCATCCGAAGAACAGATTCACGACATGGCGCAGCAATCAGGTTTACCGCCGAAAGTGATCAAGCATTGGTTCCGCAATACGCTATTCAAAGAGCGCCAGCGCAATAAAGATAGTCCGTATAATTTTAACAATCCGCCGTCGACAACGCTGAATCTGGAAGAGTACGAAAAGACTGGCGAAGCTAAAGTTATGCCCTTGAATAGTACAGGTAGCAGTGTTGAGGAGAGCAAAGCCAAAGaatcgccgcctccgccgttCGTCGCCGAAATCAAAACCGAGATGAAGGAGGAAGTGCCCGACGAACCAGTGCACAAGTACGTTGAGGAGAAGGTGCAGCAAGAGAGTGTCGACGAGAAAATGTTCAACCTGCCGCCACATCTACAACCGCCACAGAGTCCAGCTTCGTCGATGAGCAGCACCGACAACAATCATCACACGCCAGTTTCGGCACCTTCAACGCCAAATAACCTCACATTAACGTCCATTATTGCCTCGCAATTGGGCGATAGCATCATCACGACAAACACACCACCATCATCACTCAATCTAACCACATCGAGCACACCACATTCGCTCACGAGTCCAATGCTTCCACCGCCAAAGTTGAACCAGCAAAACTACCAGCCACAGAATGCACTCCAGGGCATTTTACCAATGACACCGAATCGTTGCTTGAGTCCCAATCGGGATTTCGCTATGAACACAAATAGCAACAGTTCGACGGGCAGTTCTGGTAAGCGTGCGAATCGCACTCGGTTCACGGATTATCAGATCAAAGTGCTACAAGAGTTCTTTGAGAACAACGCGTATCCGAAAGACGACGACTTGGAATATCTTTCCAAACTACTCAGTTTAAGTCCGCGCGTGATCGTAGTGTGGTTCCAAAATGCGCGGCAGAAGGCACGCAAAGTATACGAAAATCAGCCGGCGGCAGAGCCAAGTCCAGGAATGGCGGAACCCACAGCGGAGGCGGGTGCGAATCGCTTTCAGCGAACGCCAGGTCTAAATTACCAATGCAAGAAGTGCTTGTTGGTATTCCAAAGATACTATGAATTGATTCGTCATCAGAAAACGCATTGTTTTAAGGAAGAAGACGCCAAGCGTTCAGCGCAAGCGCAAGCTGCCGCCGCGCAAATTGCTGCTGTTCTCAGTTCGGAGGATTCCAATTCAAGTACGATCATTGAGCAGAATGCGCAACCACAAACACCAAACGCGCAGCAATCACAGGGCCCTTCACAGAGTCCCAGCTTACCAAACCCACCCACAACACCAACACCCAGTGGGCACAACACACGACCACCATCGCCGGCCGAATCACCAGTTGATTCCAAGCAGGATGGTACATTTCAGTGCGACAAGTGCAATTTAGTTTTTCAAAGATTTGACTTATGGAGGGAACATCAATTGGTGCATATAATGAATCCAACCCTGTTCCCCTCGTATCCACCGGATTCACCCTTTGGCATTTTACAACAGCATGCACAACTCCAGCAATTGAATGCGAATCTCGGAGTAACGGATTTGTCCAGTGATAAGTCCGCTTCGCCAATACCAATACCGCTGATTAATATGTTGAATAACGTAACAGCGCAAAAGCGAAAATTGGAGGAGTATGACGGTGAAAGTGACGTTTCGGATCAGCCTAAAGATAAGAGATTGCGCACCACAATTCTGCCAGAACAATTGGATTACTTGTATCAGAAATATCAGATTGAGAGCAACCCGTCACGGAAAATGCTTGAGAATATCGCGAGAGAAGTTGGACTGAAAAAGCGTGTTGTACAAGTGTGGTTTCAGAACACTCGCGCACGGGAGCGAAAAGGGCAATTTCGTGCGCATGCCCAAGTGATTAATAAGCGGTGTCCATTCTGTCCGGCATTGTTCAAAGTGAAGTCAGCGCTTGAGTCTCATCTAACAACCAAACATGCAGATCAATGCGCTCGTGGTGAAATCAACATTGATGCGCTGCCTGACGAAGAAGCCAGTCTGGAATCATCACCGAGCTTAAGTTCGGGTGGTGATAATAAATTCGGACCGGCACCCAACATGATGCCACCACTGTTCCCCAACCTGCACCCGGACATGGAGAACTCCATCAAGAAGTATTACGAAGAGAGCATGAAGCGGTACATCAGCGAATTGCAGGCTCACGCGTCCAACGGCGATAAGAGCGAAATTAAGAGTGTCAAGGAGGAAGGAGGAGGAGGCGGTGGTGAGATCCCTTTAGATTTATCTAAACCCGTAGATCTATCGCGTCCAATGAAGGTGAACATGGACCATGAACGCAGTTTGTGTGATCCAGGGCCCCTCACCGATCTGAGCGAGCGCTCCTTGTGCGACGAGCGCAGCGACTCCATGTCGGAGACGGCAGAGTTCATGGACGACGAGAGTAATCCAACGTCGCCGGCGAGTAGCACGCAGAGTCTGAACAATCAGGGAGGCAGCCGACAAGGTAATGCATCGAATTCATCGAGCAAGCGATTTCGCACCCAAATGTCAGCCGTACAAGTGAAAGTCATGAAGTTGCTCTTCACCGACTACAAGACGCCAACGATGGCCGAATGTGAGATGCTCGGCCGCGAAATTGGACTCCCGAAACGCGTCGTGCAAGTGTGGTTCCAAAATGCAAGGGCCAAAGAGAAGAAAGGCAAGATCGCCCTCCAGAAAGTGTTGGGCAATACAGATTCGGAGAACGCCAGCGCAGCCCTGCCAGACGATTGCAGATTCTGTAATTTCAAATACACGCACAAGTACTCGATTCAAGACCATATCTTCACCAAGAGTCATATTGCCAACGTTAAGGCGCACCTCGAAAGTTCCGGTCTTAAAGATGTGATGAATGACAGTGCTACCGAGTTCACCGTGCCGCCAATTCCGGGCGCCTCTGTGTCTGCCGACTCGACGACGAATCCACAACAGGCGCTGAACAACAACACCCACCTGCAGCTCCTCCAAATGGCCGGCATGCAGatggccgccgccgccgtcaagTCCGAGAACGACGAGAACAACCAGGAGGCCCTCTTCCAGCAGTTGTACGCCTTGGGCAGCAGCGCCAACTTCGGCAACGCGCAGAACCAGTTCCTTCACCATCCGATGTTCGGCGGCAATGGTAAGTCCCTTGCAAAACTCTTTTCTAACATTAAATCACACGCCGACACACAAGCGCACAAAAGCAGGACGCTCGCGAGTCAGTGA
Protein Sequence: MRRIAIAFDACRSAYFMCLLVFSVSLAFVRNAERRDSVNSEQSSQADQSKEFKSEPCDDNDDPMIRDAGAQHVCPYCDYASDSEMRIQAHVLAQHGTSNNNSSSEASFQCPLCQDAFKDRTSLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQASRTPTPNNAAAHHPQMPSNQMVSPNSVSSKDSAKLDKSDTAPHNNSSSGVDMENELMSPHSVGGASSDVDAGDLELERCNTCMKCFKNIDELCLHQNETGHLEIKQTPSGPGYLCWKKGCNQFFPTAHTLQMHFKEVHAKNSISQMSVSEKHVYKYRCNQCSLAFKTLEKLQIHSQYHLIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKQSLMNNPLLLAGLQGQVLDSSTNDILKKESMRADDGESLECDDSKELSTSHDDSNANDGENSDDSIVYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQNYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQQQNNNNNNPPVSPVTAGGTTSAGGGAGGIGGALGQQPQSQSLTPKSTSSSDEDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLSKPLIEQPEAMQSPKQSSPTPAAGSGGEKTSPTPPSPNPSGTPTIAAGSQGMMACPKCGALFSAPDQLSVHQQLYCMFAAPNMAIFQAQEPGLAKSPPPPSSSGGETDALGRINLPKRINSQMQKHLLESYGFDVVMHYNESQQRRHRHRESADQRTSPPAAAAANVTDDSAADATARPEEELDANLPEVSKSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKSEYEKKTVVVTAATSSTTLNSHPRVSTPSAASGSGGNPNHNNNTSSHHTLPADVVTPEKDDESKEALHAKLNLQTPPEATSTAPSTPTSSSTPASSTDSLPANIQAMIAQTMAQNPMALAQQMTEMQAALNVMQLQQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPFDAMQQFAPQEQQQAMMAAKQQQAALMQQQAAAVNAAANNQKRARTRITDDQLKILRAHFDINNSPSEEQIHDMAQQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNSTGSSVEESKAKESPPPPFVAEIKTEMKEEVPDEPVHKYVEEKVQQESVDEKMFNLPPHLQPPQSPASSMSSTDNNHHTPVSAPSTPNNLTLTSIIASQLGDSIITTNTPPSSLNLTTSSTPHSLTSPMLPPPKLNQQNYQPQNALQGILPMTPNRCLSPNRDFAMNTNSNSSTGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPAAEPSPGMAEPTAEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTIIEQNAQPQTPNAQQSQGPSQSPSLPNPPTTPTPSGHNTRPPSPAESPVDSKQDGTFQCDKCNLVFQRFDLWREHQLVHIMNPTLFPSYPPDSPFGILQQHAQLQQLNANLGVTDLSSDKSASPIPIPLINMLNNVTAQKRKLEEYDGESDVSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCARGEINIDALPDEEASLESSPSLSSGGDNKFGPAPNMMPPLFPNLHPDMENSIKKYYEESMKRYISELQAHASNGDKSEIKSVKEEGGGGGGEIPLDLSKPVDLSRPMKVNMDHERSLCDPGPLTDLSERSLCDERSDSMSETAEFMDDESNPTSPASSTQSLNNQGGSRQGNASNSSSKRFRTQMSAVQVKVMKLLFTDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKGKIALQKVLGNTDSENASAALPDDCRFCNFKYTHKYSIQDHIFTKSHIANVKAHLESSGLKDVMNDSATEFTVPPIPGASVSADSTTNPQQALNNNTHLQLLQMAGMQMAAAAVKSENDENNQEALFQQLYALGSSANFGNAQNQFLHHPMFGGNGKSLAKLFSNIKSHADTQAHKSRTLASQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00083723;
90% Identity: iTF_00049079;
80% Identity: iTF_00049079;