Basic Information

Gene Symbol
ZNF131
Assembly
GCA_963565655.1
Location
OY751416.1:5386545-5397860[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 7.8 6.6e+02 1.2 1.0 3 22 13 32 11 32 0.88
2 16 0.58 48 4.8 0.5 3 23 317 339 317 339 0.88
3 16 0.18 15 6.4 1.5 2 23 401 421 400 421 0.96
4 16 1.5 1.3e+02 3.5 3.3 1 23 453 477 453 477 0.92
5 16 0.013 1.1 10.0 1.1 2 21 534 553 533 557 0.89
6 16 0.00028 0.023 15.2 1.0 3 23 573 594 571 594 0.96
7 16 0.12 10 6.9 0.7 1 23 607 631 607 631 0.93
8 16 0.0068 0.57 10.9 2.3 2 23 649 671 649 671 0.93
9 16 0.002 0.17 12.5 0.3 1 21 676 696 676 697 0.94
10 16 8.7e-05 0.0073 16.8 0.6 1 23 758 779 758 779 0.99
11 16 0.00028 0.023 15.3 1.3 1 21 785 805 785 806 0.94
12 16 1.6e-05 0.0013 19.1 3.0 1 23 826 848 826 848 0.98
13 16 0.0018 0.15 12.7 0.0 1 23 853 878 853 878 0.96
14 16 0.0025 0.21 12.2 1.6 1 23 887 909 887 909 0.95
15 16 0.017 1.4 9.6 3.2 1 23 918 942 918 942 0.98
16 16 0.002 0.17 12.5 1.7 1 21 948 968 948 973 0.93

Sequence Information

Coding Sequence
ATGGAGAATTACGAGGATGACGATGATACACATTTCTGCATAAAGTGTCACGTGACAGTTAGTGGCCTTGACAATTACGTGCGCCACCGTCAAACCGGATGTCGTCAATCAGAGCAGAAGGATGAAGTCAGATATCCAGAAATCTTGAATGCCGATACGTTCTTCAATTCTCTAGAATTACGCAGCAGTGTCAAGCCAAAATCCAGTGACATTTCGGTGCTAAATGagcgagagaaaaaatcgCGTACAGATAAACGTAAAAAGTCGAAGAGATACGCAGAGATTGAGGAAGTTTCAGCAAAGGAAAAACTCATGACACTATCACCAGTAGTCACAGATTTAGATGATCCAACAGATCACATTGGAATTCCTTCTCTAGTGGGATTCCCCGATCTAGTTGCATTCCCCGAGAAGTCTTCTGCACCAAAGCTGCAGCCCCAAAAATTACCAGAAAAGAAGCGCACAGATGAGCATCGTGTCTGGTTGGATGACCCAATTCTCGAGGATTTAGAGAATAAACCAGCAGTATCACCAAATACCCTGGACAGTGAAGCCGAATACGACTACAGAAACGAGGATGAAACAGACATTGACAGCCCGGATGAAATCCAAGACTCCTACACTGAATCTGACGATGAGCGTGATTATTCTGGACAGGCACACACTGGTGGTAAATGGAAACCAGACCAATTACTCCAAGAAATATCACCACAAAATGACGATGAACTCGAGAATGAAGATTACCGACAGGATAGTCCACCCTCTCATACAGGTGGTAAATGGAAGCCTGAGAAGGCAGAGGAGGATGAGGTGGATGCTGATGAGGAGGACGATGAagatgaggaggaggaggaggataAGGATACCAGACAGCCACCACCAGGACATACGAGGGGCAAATGGATTCCAGGTGGTTCAGTTATTAGCGAAAATACCAGTGGATACTGGTGCACTCCCTGTGGCAGAAGGCTAGCGTCAAAATTACTTTATAACAGGCATTTGAGGTCTGATTTACACGCGAGAAGGAGTATTCAAGAGATTGAGGGCGATCTCAAGCTACCGAGGGCTATTGGTCCATTACTGAGACAGAGAACTCGGACAAGAAGACAACGAGCACTTGATATTAAAACTTCAGATAACAAGAAAGCACTGGCCAATAGACAACAAAAGATGAGGAGAAAGCGAGAAAAATTAGTATTACGATGCGAGATGTGTCATGCCCGTGTACGTCGTTCTCAGCTGGGTAAACACCTGCTCTCGCACTACCATTGCCGTGTAGCTGGATTGAATCCCTGCAGTTCTTCAGCTCGACGCTTTATACTGGAGAACATGGCAAATGTGGTACGCCAGTGTCCATTTCAGTGTACTACCTGTCGCTTTTATTGCAACACTGAGGATACTTTTTTACTGCATTGGCGTTCAGAGCTGCACAACAGTGTACCTCAAGATGAGAACAGCAATCTGACATGCGTCAGCTGTGATTTCTGGTGCGACACTAACGAAACAATGGAGAAGCATCTACTAAGCCAGAAGCATCGTGAGGCAGTGTCAATGATCAATGGATCAGTGCCAATAATAATCCGCAGACAAAGAATTCTATCATGCAACAATTGCAGTCGTCGATTCCGTTACAATCTCCAATTGCGCATTCACTCAAAGGAAACTGGACACACTGATAATTCAACGGCAACCGATGATTATCAACAGCGAATAATCTGTCAGAATTGTAGCCACGTATTTAAATCACTTGTGGCACTTCAACGTCATCAACTGACCAATCACACATCCAAAGACACAGATGGCCAACTAACAGCACCCTATTACTGTTCATTCTGCTCGATCAACTTTGAGACTGCCAGAGACGCTGTATTACATAGAAGAACCACTAGTCACAAGCAGACTGTCAAAGTCCACAAGTTTAACGGAGTTGAAATGTCAAGAAGAAGCTGTGGTCATTGTGGTGAGAAACTGAGGAATTTGGAGGAATTAAAGCAtcatttgattcaatttcattacgATCTTTGTCATCGGTGTGCAAAGTGCGGAATGATTTTTCCACTGCCACAAGACTTGACGAGGCACACGAAGAAACAGGAGtgcaaaaaattgatagattCAAAGGTTAAATCTAAGAGTCACAAATGGACATGCACAAATTGTCCATTATTCAGTACTGATTCACAATCAGAATTAATCTTTCATCAAGTTCTTCATGCTGGGAATATTGAGGCCGATCCGAATGAGGCAGGCTCGAGCAAAGTCTCGGTTAAATATCGCTGTCCATTGTGCGATAAAATATTCCCTAAAGAATCGATGAGGAATCACATCAGAAGACACACAGGAGAACGACCATTTTCATGCACCAAATGCCTCAGATCATTCTCCAGTAGATCCACCCTAAATGTGCATAATAGAAGCTGTTTATCAGGTGATAATATTGACGAGGAGAGCAGCAAGAAGATTCGCATGAGAAATTACGTTTGTTACGAGTGCAATGAAGCTTTTTATACAAAACACACATTAAGACAACACATGCTTCGTCATGCTGGCAAGAATTACAAGTGCGGAGTTCCGGGCTGTCCGACTGTTCTTCGAACAGCGAATGAGCTCAGGAACCATCGTAGACTAATCCACGAGAGTAGTGCTAGCGACCGCAACTTTTTATGCAACGAGTGCACTTATGCAGCTAAAACTAGGACACAACTTCGCCGgCACCGAGAGAAGCACAAGCCTCCGACAACTCAGACCCAATTCACCTGTCCCTATAAGGACTGCCGCTTCACCACCCAGCTCATGTCACACCTGAAGCGCCACATCCGTGTCCACACCGGTGCAAAGCCCTACAAATGTCGCCACTGTCCCTACGCCAGCAATAATCtcgagaaTTTGCGGAAACACGTGTTGTCAACGAGAAGACATCCAGGAAAAACAATTTACGAGTGTGAAACATGCAGTGCAAGTGGTGCATCTGTTTTTGCGACAAATTTCAGTAAAGAATTACGTGCACACTTAGTAGAGACTCATCCAGACTTATTCCCAACTACCAATCATGCAATTGATTACgtatcaaaattatttgatagaaattttgataattaa
Protein Sequence
MENYEDDDDTHFCIKCHVTVSGLDNYVRHRQTGCRQSEQKDEVRYPEILNADTFFNSLELRSSVKPKSSDISVLNEREKKSRTDKRKKSKRYAEIEEVSAKEKLMTLSPVVTDLDDPTDHIGIPSLVGFPDLVAFPEKSSAPKLQPQKLPEKKRTDEHRVWLDDPILEDLENKPAVSPNTLDSEAEYDYRNEDETDIDSPDEIQDSYTESDDERDYSGQAHTGGKWKPDQLLQEISPQNDDELENEDYRQDSPPSHTGGKWKPEKAEEDEVDADEEDDEDEEEEEDKDTRQPPPGHTRGKWIPGGSVISENTSGYWCTPCGRRLASKLLYNRHLRSDLHARRSIQEIEGDLKLPRAIGPLLRQRTRTRRQRALDIKTSDNKKALANRQQKMRRKREKLVLRCEMCHARVRRSQLGKHLLSHYHCRVAGLNPCSSSARRFILENMANVVRQCPFQCTTCRFYCNTEDTFLLHWRSELHNSVPQDENSNLTCVSCDFWCDTNETMEKHLLSQKHREAVSMINGSVPIIIRRQRILSCNNCSRRFRYNLQLRIHSKETGHTDNSTATDDYQQRIICQNCSHVFKSLVALQRHQLTNHTSKDTDGQLTAPYYCSFCSINFETARDAVLHRRTTSHKQTVKVHKFNGVEMSRRSCGHCGEKLRNLEELKHHLIQFHYDLCHRCAKCGMIFPLPQDLTRHTKKQECKKLIDSKVKSKSHKWTCTNCPLFSTDSQSELIFHQVLHAGNIEADPNEAGSSKVSVKYRCPLCDKIFPKESMRNHIRRHTGERPFSCTKCLRSFSSRSTLNVHNRSCLSGDNIDEESSKKIRMRNYVCYECNEAFYTKHTLRQHMLRHAGKNYKCGVPGCPTVLRTANELRNHRRLIHESSASDRNFLCNECTYAAKTRTQLRRHREKHKPPTTQTQFTCPYKDCRFTTQLMSHLKRHIRVHTGAKPYKCRHCPYASNNLENLRKHVLSTRRHPGKTIYECETCSASGASVFATNFSKELRAHLVETHPDLFPTTNHAIDYVSKLFDRNFDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00047566; iTF_00046551;
90% Identity
iTF_00047566;
80% Identity
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