Basic Information

Gene Symbol
-
Assembly
None
Location
Contig17:4790546-4797039[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 2e-05 0.0008 19.3 1.5 3 23 214 235 212 235 0.97
2 16 0.014 0.57 10.3 2.5 1 23 256 279 256 279 0.95
3 16 1.2 48 4.2 2.2 2 23 296 318 295 318 0.92
4 16 2.2 91 3.3 2.7 1 23 325 348 325 348 0.94
5 16 0.0027 0.11 12.5 0.4 2 23 459 481 459 481 0.96
6 16 3e-06 0.00012 21.8 4.0 2 23 489 511 488 511 0.95
7 16 0.0048 0.19 11.8 1.8 2 23 752 774 751 774 0.96
8 16 0.3 12 6.1 1.6 1 23 796 819 796 819 0.96
9 16 0.025 1 9.5 1.6 2 23 827 849 826 849 0.96
10 16 9.6e-05 0.0039 17.1 0.4 2 23 950 972 950 972 0.96
11 16 8.3e-07 3.4e-05 23.6 2.5 3 23 981 1002 980 1002 0.97
12 16 0.076 3.1 8.0 4.0 1 23 1024 1046 1024 1047 0.95
13 16 1.8e-05 0.00072 19.4 1.1 1 23 1053 1075 1053 1075 0.96
14 16 2.3e-05 0.00095 19.0 2.6 1 23 1081 1103 1081 1103 0.99
15 16 2.1e-07 8.4e-06 25.5 0.8 2 23 1110 1131 1109 1131 0.98
16 16 2.4e-05 0.00099 19.0 0.2 2 22 1138 1158 1137 1161 0.89

Sequence Information

Coding Sequence
ATGTCTGATAAGGCAGTACAAAAGTGTAGGACTTGTCTAAAGAACAGTACAAAAACTTTTCCTTTAACCAAATATGCCATAGGATGTAACCCAAAGACGACCTATGGTCAACTATTAAAGGAATATGCCAGTTTACAGTTTCCAACCGATTATGAGCGATACATGCCACAAAATTTATGTTTATTATGCTGCCGCGAATTGCGGAACGTTTATACTTTCACTCGACAAGCCCAATATTGTAATAACAAATTAATAAATGTTATTGCTAAACAATTAGCTAGTCTGAAAGAAAAGACAGTTATTTTGCCAGAAAATGGAAACAAATTGGAAAAATCTCTTAACATCAAAATGGAGAATAATATTGATGATTGTAATATCAATCAGCAACAGTTTTCTATGATTAATGAGTTCAGAATTGTAAGCACAAGTGTACTTTTAAAGTCGGAAGTTTTGGAAGAATCTGCAGATAATGAAGGACCAATTCAATACTATGTTGATGATAATGACGAAATGGAAATTAATGAAAACGATCGAAATGACTCAAATGATTCTACGCTGGACTTTTCTATGACCTCTGATTGTAATATAACTGCCAAATATCTAATTGAAAATAATGACAATTCTCAAAATAATACATTCTGTCCGATATGTGATAAAATTAGTAACAGACATGATAATTTAGTAACTCATATGCGCACTCAACATGATTTTGAAGTGCCTAAAGAATTTTTAAACATACAAAAGCCAGTGCTAAAAGCTCAAATGTTTGCCTGTAAAAAATGTCCTTGTAAATTTGCCAATAAGAACAAGTATTTAATTCATTTAAAAGAAGTACATGGGAGTGAAGAGAAAAAAGTAAAACAAAAACCAGTGGATAAAATTATTAAATGTCGTTTTTGTGACTATACATCTCGGACGTATTCGGCTTTAAACTTCCACAATCGTTCGAAACATGGTACCGAAGAAGATAAATTCAAGTGCAAATTTTGCCCCTACATGACCCTGAAAAAATTTAGTTTGTTAACGCATGTAAAAAATTCACATAAAGAATTAATAAAAACACTCAAGGCTGATGCCGAAAACAAAACGGATCAAAGAGGAACCTTAAATAAGGCTAATATTAAAAATAATAATGTTTTAACAACATCTAAATTTGCAACTTCTCAAGAAGACGTAGATAATTCTGTACATGAAAATGAAGACTCTTCTACCGATGATGATAGCCCTTTAGCCCACAAAAACTTTATCAAATCTTTTGATACATCTGAAATGGAAGAGAATAAGAAAGAATTAAGTGAGGAAATGTTTATAAGAAACATTTTCAATATCAAAAAGAGACAATGTAACACAATATCAACAAAATCTTTACCCAGACGATGTGATATCTGCGGAAATATTTATAATAACTACAATGCTCTTAAGACCCATCAAAAAAACGTTCACATTGGCATAGAAAAATACTGTGTATGTTCGCATTGTGGTAAACAATTTAAAAGAAAAGCTAATCTTAGGATCCATATTAAAAATGCTCATGTACCAAAAAAATCCACAGAAATTGTTAAACAACCACCATCAGCTCCCAAAGAGAAACGTTTTATGTGCACAGACTGTTTCTATTTTACATCAGATTATGAGCGCCTCATGCCTCAACATTTATGTGTTTTGTGCTGTCGTGAGTTGAGGTCCACAAATGCATTTGTTCGTAAAGCCAAGCATTCCTATAATGAACTTATAAATCTTATTTCAAAACAATTGGATTGTCTGCAAGAAAAAACTATTGATTTGCCACCAAATGGAAACGAATTGGAAAAATTCCTTGATATCAAAATAGAAGATTATATAGATGAATTCCATGCGATAGAACGAAAAGGCAAAGATAATACAACAGATGGACTCAACATTGTAATCACGAGTACTATGTTGAAGTCTGAAGTATGGGAGGAATCAACAGATAATGGCAAAACTATTAAAAAGGATGAAGATATTGATGAAATGAATATTATTGATAATGTTCAAAATGACTTAAATGATTCAACATTGGAAAGATCAACGATGACCGATACTAATAAAGCTGCCCCATATATAACCGATAACGCTGAGTCTTCTGAATATAAAATTGACACAGTGTGTCTAATAAGTGATCAAACAGAGAGCAGTCCGGATAATTTATTAACACTATTGCATACACAAAATGATATTACAGAAGATAGCAAATCTTTAGACTCACAAAAACCCAAAACAAAAAAAACACTTGTTTGTAAATTATGTCCCATGAAATATACTAATAAAACCACGTACTTGAATCATCTAAAGAAGAAACATGACATTGATGAGAAACAGCACATCAATGAAACAAGCGAAAAAGAAGAGCAGATGCTTAAAATTTATAAATGTCTTTCATGTGATTATACAGCTAAATCTTTTCCTACTCTAAGATATCACACTCGTGCGAAACATGGAAGCGAAAAGGACAAACTCCCTTGCAAGTTTTGTTCACAAACATTTTTGCAGAAATTTGATTTATTAATGCATATGAAAAAATCACACAATGAACTGATAAAGACACTTAAAGGTGAAGCTGAAAATAAAGTGGATGAAGGTGAATCTCTCAAAAATATTAACATGTTGCCACTAGAAGATGATAGTTCTCTAGATGAAAATGAAGACTATTCTAGCGATGACAGCATTCCTTTGGCCCACAAAATCGATAAGTCGCATTCAATGTCAAGCTTAAACACTGCAATGGACGTAGAAAAGGAGGCATTTAGTGATGAAGAGTTCATAAGAAACATGATAAGTTTAAAAAAAAGACCCCCTAAATCGATATCGAACAAATCTCTAGCCAGAAGCTGTGATAAATGTGGAAAAATTTATAAAAACTACGGTACTCTTTATGCCCACCAAAGATACGTTCATATCAGCGAAGAAAAATACAGTTTATGTCCACATTGTGGTAAAAAATTCAAAAGGAAAACTAATCTAAGGATTCACATAAATAATATTCATGTTGCCAACAATTCAAAAGAAATTGTTAAAAAACCCACAGCACCTAAAGTTAAAGAAAAGCGGTTTATGTGTACGGAATGTTCCTACGTTTGCGGTACAATAACCACATTAACAATACACAGAAATCGTCACCATACAGGGGAAAAACCATATAAATGTGAATATTGTCCCAAATCGTTTGTGGTATCGTACGACTTGAAACTTCATCGTTATTTACACACCGGCGAAAGACCTTTCAAATGTTCGATATGTTCAAAGGGATTCCAAGACAATGCCCATCTGGTTAAACACAAACGCATGCACAATAGTTTGCCGCCTAACCAGTGTGACGATTGCGGTAAACGTTTTACCCAGTCGTACAATTTATTAGCTCACAAAAGAATTCATCTCAGAGAGAAAAAACTCAATTGTACGATTTGTGGTAAAGTATTTGAGAATAGATCGTTATTAAATATACATCGTATAAGTGAAAATCATCATGATGAAATTATATAA
Protein Sequence
MSDKAVQKCRTCLKNSTKTFPLTKYAIGCNPKTTYGQLLKEYASLQFPTDYERYMPQNLCLLCCRELRNVYTFTRQAQYCNNKLINVIAKQLASLKEKTVILPENGNKLEKSLNIKMENNIDDCNINQQQFSMINEFRIVSTSVLLKSEVLEESADNEGPIQYYVDDNDEMEINENDRNDSNDSTLDFSMTSDCNITAKYLIENNDNSQNNTFCPICDKISNRHDNLVTHMRTQHDFEVPKEFLNIQKPVLKAQMFACKKCPCKFANKNKYLIHLKEVHGSEEKKVKQKPVDKIIKCRFCDYTSRTYSALNFHNRSKHGTEEDKFKCKFCPYMTLKKFSLLTHVKNSHKELIKTLKADAENKTDQRGTLNKANIKNNNVLTTSKFATSQEDVDNSVHENEDSSTDDDSPLAHKNFIKSFDTSEMEENKKELSEEMFIRNIFNIKKRQCNTISTKSLPRRCDICGNIYNNYNALKTHQKNVHIGIEKYCVCSHCGKQFKRKANLRIHIKNAHVPKKSTEIVKQPPSAPKEKRFMCTDCFYFTSDYERLMPQHLCVLCCRELRSTNAFVRKAKHSYNELINLISKQLDCLQEKTIDLPPNGNELEKFLDIKIEDYIDEFHAIERKGKDNTTDGLNIVITSTMLKSEVWEESTDNGKTIKKDEDIDEMNIIDNVQNDLNDSTLERSTMTDTNKAAPYITDNAESSEYKIDTVCLISDQTESSPDNLLTLLHTQNDITEDSKSLDSQKPKTKKTLVCKLCPMKYTNKTTYLNHLKKKHDIDEKQHINETSEKEEQMLKIYKCLSCDYTAKSFPTLRYHTRAKHGSEKDKLPCKFCSQTFLQKFDLLMHMKKSHNELIKTLKGEAENKVDEGESLKNINMLPLEDDSSLDENEDYSSDDSIPLAHKIDKSHSMSSLNTAMDVEKEAFSDEEFIRNMISLKKRPPKSISNKSLARSCDKCGKIYKNYGTLYAHQRYVHISEEKYSLCPHCGKKFKRKTNLRIHINNIHVANNSKEIVKKPTAPKVKEKRFMCTECSYVCGTITTLTIHRNRHHTGEKPYKCEYCPKSFVVSYDLKLHRYLHTGERPFKCSICSKGFQDNAHLVKHKRMHNSLPPNQCDDCGKRFTQSYNLLAHKRIHLREKKLNCTICGKVFENRSLLNIHRISENHHDEII

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-